BR112016026956A2 - método para a produção enzimática de d-eritrose e acetilfosfato". - Google Patents

método para a produção enzimática de d-eritrose e acetilfosfato".

Info

Publication number
BR112016026956A2
BR112016026956A2 BR112016026956A BR112016026956A BR112016026956A2 BR 112016026956 A2 BR112016026956 A2 BR 112016026956A2 BR 112016026956 A BR112016026956 A BR 112016026956A BR 112016026956 A BR112016026956 A BR 112016026956A BR 112016026956 A2 BR112016026956 A2 BR 112016026956A2
Authority
BR
Brazil
Prior art keywords
erythrose
glycolaldehyde
acetyl phosphate
aldolase
enzymatic production
Prior art date
Application number
BR112016026956A
Other languages
English (en)
Inventor
Marliere Philippe
Original Assignee
Scientist Of Fortune Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scientist Of Fortune Sa filed Critical Scientist Of Fortune Sa
Publication of BR112016026956A2 publication Critical patent/BR112016026956A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C12N9/92—Glucose isomerase (5.3.1.5; 5.3.1.9; 5.3.1.18)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/02—Monosaccharides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/38—Nucleosides
    • C12P19/40—Nucleosides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same ring, e.g. purine nucleosides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26—Ketones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P9/00—Preparation of organic compounds containing a metal or atom other than H, N, C, O, S or halogen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01008—Phosphate acetyltransferase (2.3.1.8)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/03—Acyl groups converted into alkyl on transfer (2.3.3)
    • C12Y203/03015—Sulfoacetaldehyde acetyltransferase (2.3.3.15)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y401/00—Carbon-carbon lyases (4.1)
    • C12Y401/02—Aldehyde-lyases (4.1.2)
    • C12Y401/02004—Deoxyribose-phosphate aldolase (4.1.2.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y401/00—Carbon-carbon lyases (4.1)
    • C12Y401/02—Aldehyde-lyases (4.1.2)
    • C12Y401/02009—Phosphoketolase (4.1.2.9)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y503/00—Intramolecular oxidoreductases (5.3)
    • C12Y503/01—Intramolecular oxidoreductases (5.3) interconverting aldoses and ketoses (5.3.1)
    • C12Y503/01005—Xylose isomerase (5.3.1.5)

Abstract

é descrito um método para a produção de d-eritrose e acetilfosfato, que compreende a conversão enzimática de d-frutose em d-eritrose e acetilfosfato fazendo uso de uma fosfocetolase. a d-eritrose produzida pode ainda ser convertida em glicolaldeído por um método para a produção de glicolaldeído que compreende a conversão enzimática de d-eritrose em glicolaldeído fazendo uso de uma aldolase, em que a referida aldolase é uma 2-desoxirribose-5-fosfato aldolase (ec 4.1.2.4) ou uma frutose-bisfosfato aldolase (ec 4.1.2.13). o glicolaldeído produzido pode finalmente ser convertido em acetilfosfato por conversão enzimática do assim produzido glicolaldeído em acetilfosfato, fazendo uso de uma fosfocetolase ou de uma sulfoacetaldeído acetiltransferase.
BR112016026956A 2014-05-26 2015-05-22 método para a produção enzimática de d-eritrose e acetilfosfato". BR112016026956A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14169813 2014-05-26
PCT/EP2015/061391 WO2015181074A1 (en) 2014-05-26 2015-05-22 Method for the enzymatic production of d-erythrose and acetyl phosphate

Publications (1)

Publication Number Publication Date
BR112016026956A2 true BR112016026956A2 (pt) 2017-10-31

Family

ID=50774718

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016026956A BR112016026956A2 (pt) 2014-05-26 2015-05-22 método para a produção enzimática de d-eritrose e acetilfosfato".

Country Status (8)

Country Link
US (1) US10415067B2 (pt)
EP (1) EP3149180B1 (pt)
JP (1) JP2017516475A (pt)
CN (1) CN106536742B (pt)
AU (1) AU2015266132A1 (pt)
BR (1) BR112016026956A2 (pt)
CA (1) CA2947212A1 (pt)
WO (1) WO2015181074A1 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017516475A (ja) * 2014-05-26 2017-06-22 サイエンティスト・オブ・フォーチュン・ソシエテ・アノニム Ｄ−エリトロースおよびアセチルリン酸の酵素的生成方法
JP2018527937A (ja) * 2015-09-10 2018-09-27 サイエンティスト・オブ・フォーチュン・ソシエテ・アノニム ２−ヒドロキシアルデヒドからのアシルリン酸の酵素的産生
GB201605354D0 (en) * 2016-03-30 2016-05-11 Zuvasyntha Ltd Modified enzyme
CN106755172B (zh) * 2016-12-16 2020-07-28 中国科学院天津工业生物技术研究所 利用乙醇醛合成乙酰辅酶a及其衍生产品的新途径
CN106916794B (zh) * 2017-02-22 2019-10-11 中国科学院天津工业生物技术研究所 催化甲醛合成羟基乙醛的酶及其应用
EP3821015A4 (en) 2018-07-09 2022-07-13 Codexis, Inc. DEOXYRIBOSE-PHOSPHATE MODIFIED ALDOLASES
CN112513282A (zh) * 2018-07-27 2021-03-16 环球生物能源公司 从磷酸二羟丙酮和甘油醛-3-磷酸产生果糖-6-磷酸的方法
JP2022520814A (ja) 2019-02-15 2022-04-01 ブラスケム エス．エー． 逆グリオキシル酸短絡を通じたグリコール酸およびグリシンの生成のための微生物および方法
EP3927816A1 (en) * 2019-02-20 2021-12-29 Braskem S.A. Degradation pathway for pentose and hexose sugars
CN110283733B (zh) * 2019-06-20 2020-10-27 浙江工业大学 土星轮头酵母zjph1807及其应用
WO2021063958A1 (en) * 2019-09-30 2021-04-08 Global Bioenergies Improved means and methods for increasing the yield of acetyl-coa from glucose
KR20230048250A (ko) * 2020-05-12 2023-04-11 아처 다니엘 미드랜드 캄파니 C-4 당 및 케토스 당의 제조 공정
CN112852890A (zh) * 2020-08-27 2021-05-28 中国科学院天津工业生物技术研究所 多羟基二酮以及羟基呋喃酮类化合物的生物合成方法
CN114540331B (zh) * 2021-11-01 2024-02-02 北京化工大学 具有催化乙醇醛合成d-赤藓糖功能的酶及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7253001B2 (en) 2002-03-19 2007-08-07 Forskarpatent I Syd Ab Metabolic engineering for improved xylose utilisation of Saccharomyces cerevisiae
EP1734129B1 (en) * 2004-03-29 2016-02-24 Mitsui Chemicals, Inc. Process for production of chiral hydroxyaldehydes
RU2004124226A (ru) 2004-08-10 2006-01-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) Использование фосфокетолазы для продукции полезных метаболитов
EP2773978A1 (en) * 2011-10-31 2014-09-10 Raytheon Company Methods and apparatus for wide area synthetic aperture radar detection
JP2017516475A (ja) * 2014-05-26 2017-06-22 サイエンティスト・オブ・フォーチュン・ソシエテ・アノニム Ｄ−エリトロースおよびアセチルリン酸の酵素的生成方法

Also Published As

Publication number Publication date
CN106536742B (zh) 2021-08-27
EP3149180A1 (en) 2017-04-05
WO2015181074A1 (en) 2015-12-03
EP3149180B1 (en) 2020-07-22
AU2015266132A1 (en) 2016-11-17
US20170191095A1 (en) 2017-07-06
US10415067B2 (en) 2019-09-17
JP2017516475A (ja) 2017-06-22
CN106536742A (zh) 2017-03-22
CA2947212A1 (en) 2015-12-03

Similar Documents

Publication Publication Date Title
BR112016026956A2 (pt) método para a produção enzimática de d-eritrose e acetilfosfato".
BR112017004744A2 (pt) corpo vegetal enxertado e método para a produção do mesmo
CL2019001607A1 (es) Producción enzimática de d-alulosa.
BR112018006587A2 (pt) produção enzimática de d-tagatose
BR112017002918A2 (pt) sistema e método para gerar as formas de onda e a utilização das mesmas
BR112017010923A2 (pt) misturas de milho que incluem milho com alto teor de óleo e métodos de fabricar um ou mais produtos bioquímicos usando milho com alto teor de óleo ou misturas de milho que incluem milho com alto teor de óleo
BR112016001026A2 (pt) organismo geneticamente modificado
BR112014004929A2 (pt) conversão de unidades de alquilação de hf para processos de alquilação catalisada por líquido iônico
AR103077A1 (es) Método para la producción de un sistema de administración farmacéutica
BR112017019057A2 (pt) ?variantes de piruvato desidrogenase, um micro- organismo que compreende as mesmas e um método para produzir l-aminoácido com o uso das mesmas?
BR112018001231A2 (pt) microrganismos para produzir putrescina ou ornitina e processo para produzir putrescina ou ornitina usando os mesmos
BR112017004231A2 (pt) processo para produzir um precipitado estável enriquecido em ficobiliproteínas
BR112017008595A2 (pt) composições e métodos referentes à beta-glucosidase
BR112015032121A2 (pt) Mutante de subunidade beta-prime (subunidade b') de rna polimerase, microrganismo do gênero corynebacterium e método para produzir l-lisina
CO2017000367A2 (es) Producción microbiana de dioles grasos
BR112016029391A2 (pt) métodos, reagentes e células para biossintetizar compostos
BR112017010654A2 (pt) processos para conversão de ácido mevalônico biologicamente derivado
BR112016028527A2 (pt) micro-organismo produtor de o-acetil-homoserina e método para produção de o-acetil homoserina usando o mesmo
BR112015027721A2 (pt) variantes da enol-desidratase
FI20165756A (fi) Menetelmä ja järjestelmä biokaasun tuottamiseksi
BR112016002105A2 (pt) Microrganismo modificado, método para produzir alanina e uso de um microrganismo modificado
BR112015032655A2 (pt) Micro-organismo recombinante, sistema livre de células, planta, parte de planta ou célula de planta, produto, método para aumentar biomassa ou produção de óleo em uma planta, e, semente de planta
BR112017023969A2 (pt) ?microrganismo do gênero escherichia que produz l-triptofano e um método para produzir l- triptofano com o uso do mesmo?
AR112587A1 (es) Psicosa-6-fosfato fosfatasa, composición para producir d-psicosa que comprende la enzima y métodos para producir d-psicosa utilizando la enzima
BR112016027689A2 (pt) produção de ésteres alquílicos de ácidos graxos usando tratamento cáustico

Legal Events

Date Code Title Description
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A ANUIDADE.

B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements