CN1922146A - 四氢喹啉酮及其作为促代谢谷氨酸受体拮抗剂的用途 - Google Patents
四氢喹啉酮及其作为促代谢谷氨酸受体拮抗剂的用途 Download PDFInfo
- Publication number
- CN1922146A CN1922146A CNA2005800060497A CN200580006049A CN1922146A CN 1922146 A CN1922146 A CN 1922146A CN A2005800060497 A CNA2005800060497 A CN A2005800060497A CN 200580006049 A CN200580006049 A CN 200580006049A CN 1922146 A CN1922146 A CN 1922146A
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- Prior art keywords
- quinoline
- dihydro
- ketone
- alkyl
- dimethyl
- Prior art date
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- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
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- Chemical & Material Sciences (AREA)
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- Neurology (AREA)
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- Addiction (AREA)
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- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Diabetes (AREA)
- Psychology (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Hematology (AREA)
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- Endocrinology (AREA)
- Cardiology (AREA)
- Physical Education & Sports Medicine (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54878804P | 2004-02-27 | 2004-02-27 | |
| US60/548,788 | 2004-02-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1922146A true CN1922146A (zh) | 2007-02-28 |
Family
ID=34911013
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2005800060497A Pending CN1922146A (zh) | 2004-02-27 | 2005-02-25 | 四氢喹啉酮及其作为促代谢谷氨酸受体拮抗剂的用途 |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US7598384B2 (https=) |
| EP (1) | EP1723116B1 (https=) |
| JP (1) | JP4712027B2 (https=) |
| KR (1) | KR100846347B1 (https=) |
| CN (1) | CN1922146A (https=) |
| AR (1) | AR049006A1 (https=) |
| AT (1) | ATE409182T1 (https=) |
| AU (1) | AU2005217199B2 (https=) |
| BR (1) | BRPI0508225A (https=) |
| CA (1) | CA2556653C (https=) |
| DE (1) | DE602005009929D1 (https=) |
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| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| CN102838532A (zh) | 2006-11-24 | 2012-12-26 | Ac免疫有限公司 | 用于治疗与淀粉样物质或淀粉样蛋白有关的疾病的吡唑胺和噻唑胺衍生物 |
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| US3501479A (en) * | 1967-05-19 | 1970-03-17 | American Cyanamid Co | Dihydroquinolines and substituted dihydroquinolines and method of preparing the same |
| DE2001572A1 (de) | 1970-01-15 | 1971-07-22 | Agfa Gevaert Ag | Spektral sensibilisiertes lichtempfindliches Material |
| DE2449030A1 (de) | 1974-10-11 | 1976-05-20 | Schering Ag | Neue pyridin-derivate |
| WO1988002251A1 (en) | 1986-09-26 | 1988-04-07 | Ici Australia Operations Proprietary Limited | Sunscreen compositions and compounds for use therein |
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| CN1703403A (zh) * | 2000-10-02 | 2005-11-30 | 詹森药业有限公司 | 趋代谢的谷氨酸盐受体拮抗剂 |
| CN1642580B (zh) * | 2002-03-29 | 2010-05-26 | 詹森药业有限公司 | 放射性标记的喹啉和喹啉酮衍生物及其作为代谢性谷氨酸受体配体的制造用途 |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104262243A (zh) * | 2009-10-15 | 2015-01-07 | Ac免疫有限公司 | 用于治疗与淀粉状蛋白有关的疾病或用于治疗眼部疾病的2,6-二氨基吡啶化合物 |
| CN104262243B (zh) * | 2009-10-15 | 2017-04-12 | Ac免疫有限公司 | 用于治疗与淀粉状蛋白有关的疾病或用于治疗眼部疾病的2,6‑二氨基吡啶化合物 |
| CN103298789A (zh) * | 2010-11-16 | 2013-09-11 | 通用电气健康护理有限公司 | 作为τ蛋白病理成像探针的杂环化合物 |
| CN104755471A (zh) * | 2012-08-30 | 2015-07-01 | 日本新药株式会社 | 吡啶衍生物及药物 |
| CN104513200A (zh) * | 2013-09-26 | 2015-04-15 | 江苏苏中药业集团股份有限公司 | 取代丁烯酰胺的马来酸盐及其晶型 |
| CN104513200B (zh) * | 2013-09-26 | 2017-05-03 | 江苏苏中药业集团股份有限公司 | 取代丁烯酰胺的马来酸盐及其晶型 |
Also Published As
| Publication number | Publication date |
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| CA2556653A1 (en) | 2005-09-09 |
| EP1723116A2 (en) | 2006-11-22 |
| JP4712027B2 (ja) | 2011-06-29 |
| PL1723116T3 (pl) | 2009-04-30 |
| US7598384B2 (en) | 2009-10-06 |
| SI1723116T1 (sl) | 2009-04-30 |
| KR20070001975A (ko) | 2007-01-04 |
| CA2556653C (en) | 2011-08-16 |
| KR100846347B1 (ko) | 2008-07-15 |
| AU2005217199A1 (en) | 2005-09-09 |
| IL177524A0 (en) | 2006-12-10 |
| EP1723116B1 (en) | 2008-09-24 |
| DK1723116T3 (da) | 2009-02-02 |
| JP2007524710A (ja) | 2007-08-30 |
| TW200534857A (en) | 2005-11-01 |
| EA010656B1 (ru) | 2008-10-30 |
| UA83549C2 (uk) | 2008-07-25 |
| UY28775A1 (es) | 2005-04-29 |
| WO2005082856A3 (en) | 2005-11-24 |
| IL177524A (en) | 2012-02-29 |
| PT1723116E (pt) | 2009-01-02 |
| BRPI0508225A (pt) | 2007-07-17 |
| AU2005217199B2 (en) | 2008-06-26 |
| US20050197361A1 (en) | 2005-09-08 |
| EA200601556A1 (ru) | 2007-02-27 |
| WO2005082856A2 (en) | 2005-09-09 |
| ATE409182T1 (de) | 2008-10-15 |
| ES2315853T3 (es) | 2009-04-01 |
| TWI301760B (en) | 2008-10-11 |
| ZA200606686B (en) | 2008-01-30 |
| AR049006A1 (es) | 2006-06-21 |
| DE602005009929D1 (de) | 2008-11-06 |
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