CN1842343A - 经修饰环孢菌素用于治疗hcv疾病的用途 - Google Patents

经修饰环孢菌素用于治疗hcv疾病的用途 Download PDF

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Publication number
CN1842343A
CN1842343A CNA2004800246044A CN200480024604A CN1842343A CN 1842343 A CN1842343 A CN 1842343A CN A2004800246044 A CNA2004800246044 A CN A2004800246044A CN 200480024604 A CN200480024604 A CN 200480024604A CN 1842343 A CN1842343 A CN 1842343A
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China
Prior art keywords
cyclosporin
meleu
hcv
ethyl
hydroxyl
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Chinese (zh)
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土方诚
下远野邦忠
渡士幸一
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Novartis AG
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Novartis AG
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CNA2004800246044A 2003-09-03 2004-09-02 经修饰环孢菌素用于治疗hcv疾病的用途 Pending CN1842343A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0320638.0A GB0320638D0 (en) 2003-09-03 2003-09-03 Organic compounds
GB0320638.0 2003-09-03

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CN1842343A true CN1842343A (zh) 2006-10-04

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CNA2004800246044A Pending CN1842343A (zh) 2003-09-03 2004-09-02 经修饰环孢菌素用于治疗hcv疾病的用途

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US (1) US7968518B2 (https=)
EP (2) EP1797892B1 (https=)
JP (1) JP4688806B2 (https=)
KR (1) KR101116968B1 (https=)
CN (1) CN1842343A (https=)
AU (2) AU2004268382A1 (https=)
BR (1) BRPI0414062B8 (https=)
CA (1) CA2537137C (https=)
CY (1) CY1110506T1 (https=)
DE (1) DE602004022061D1 (https=)
DK (1) DK1663287T3 (https=)
ES (1) ES2328361T3 (https=)
GB (1) GB0320638D0 (https=)
HR (1) HRP20090535T1 (https=)
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Cited By (3)

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CN102083852A (zh) * 2008-06-06 2011-06-01 西尼克斯公司 环孢菌素类似物及其在治疗hcv感染中的应用
CN102202679A (zh) * 2008-11-06 2011-09-28 帝柏奥研究制药有限公司 环十一缩酚酸肽化合物及其作为药物的用途
CN105056207A (zh) * 2007-01-04 2015-11-18 德比奥法姆国际股份有限公司 用于治疗Ullrich先天性肌营养不良的非免疫抑制性环孢霉素

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Cited By (4)

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Publication number Priority date Publication date Assignee Title
CN105056207A (zh) * 2007-01-04 2015-11-18 德比奥法姆国际股份有限公司 用于治疗Ullrich先天性肌营养不良的非免疫抑制性环孢霉素
CN102083852A (zh) * 2008-06-06 2011-06-01 西尼克斯公司 环孢菌素类似物及其在治疗hcv感染中的应用
CN102202679A (zh) * 2008-11-06 2011-09-28 帝柏奥研究制药有限公司 环十一缩酚酸肽化合物及其作为药物的用途
CN102202679B (zh) * 2008-11-06 2014-05-07 帝柏奥研究制药有限公司 环十一缩酚酸肽化合物及其作为药物的用途

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HK1091732A1 (en) 2007-01-26
CY1110506T1 (el) 2015-04-29
KR20060132798A (ko) 2006-12-22
BRPI0414062B1 (pt) 2019-06-25
NZ545495A (en) 2010-01-29
EP1663287A1 (en) 2006-06-07
KR101116968B1 (ko) 2012-03-14
US7968518B2 (en) 2011-06-28
IS2917B (is) 2014-12-15
IS8371A (is) 2006-03-24
TWI342782B (en) 2011-06-01
EP1797892A1 (en) 2007-06-20
TW200524626A (en) 2005-08-01
CA2537137C (en) 2013-05-28
HRP20090535T1 (hr) 2009-11-30
JP2007504260A (ja) 2007-03-01
TNSN06071A1 (en) 2007-10-03
WO2005021028A1 (en) 2005-03-10
US20070275884A1 (en) 2007-11-29
NO20061479L (no) 2006-06-02
BRPI0414062A (pt) 2006-10-24
RU2389501C2 (ru) 2010-05-20
PT1663287E (pt) 2009-09-03
AU2008203031A1 (en) 2008-07-31
AU2008203031B2 (en) 2011-04-07
ZA200601550B (en) 2007-05-30
BRPI0414062B8 (pt) 2021-05-25
MA28032A1 (fr) 2006-07-03
DE602004022061D1 (de) 2009-08-27
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