CN1674930A - 包含组合物的酶,所述组合物的生产工艺及其用途 - Google Patents

包含组合物的酶,所述组合物的生产工艺及其用途 Download PDF

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Publication number
CN1674930A
CN1674930A CNA038194724A CN03819472A CN1674930A CN 1674930 A CN1674930 A CN 1674930A CN A038194724 A CNA038194724 A CN A038194724A CN 03819472 A CN03819472 A CN 03819472A CN 1674930 A CN1674930 A CN 1674930A
Authority
CN
China
Prior art keywords
described compositions
enzyme
compositions
component
pepsin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA038194724A
Other languages
English (en)
Chinese (zh)
Inventor
I·哈伯莱恩
R·古根伯格
W·维恩曼
O·卡普勒
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
3M Deutschland GmbH
Original Assignee
3M Espe AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3M Espe AG filed Critical 3M Espe AG
Publication of CN1674930A publication Critical patent/CN1674930A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/488—Aspartic endopeptidases (3.4.23), e.g. pepsin, chymosin, renin, cathepsin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
CNA038194724A 2002-08-15 2003-05-16 包含组合物的酶,所述组合物的生产工艺及其用途 Pending CN1674930A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10237317A DE10237317B4 (de) 2002-08-15 2002-08-15 Enzymhaltige Zusammensetzung, Verfahren zu deren Herstellung und deren Verwendung
DE10237317.5 2002-08-15

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201010147372.9A Division CN101810856B (zh) 2002-08-15 2003-05-16 包含酶的组合物及酶的用途

Publications (1)

Publication Number Publication Date
CN1674930A true CN1674930A (zh) 2005-09-28

Family

ID=31501753

Family Applications (2)

Application Number Title Priority Date Filing Date
CNA038194724A Pending CN1674930A (zh) 2002-08-15 2003-05-16 包含组合物的酶,所述组合物的生产工艺及其用途
CN201010147372.9A Expired - Fee Related CN101810856B (zh) 2002-08-15 2003-05-16 包含酶的组合物及酶的用途

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201010147372.9A Expired - Fee Related CN101810856B (zh) 2002-08-15 2003-05-16 包含酶的组合物及酶的用途

Country Status (9)

Country Link
US (2) US20060115436A1 (https=)
EP (2) EP1530481B1 (https=)
JP (2) JP4571859B2 (https=)
CN (2) CN1674930A (https=)
AT (1) ATE541583T1 (https=)
AU (2) AU2003240667C1 (https=)
CA (1) CA2490721A1 (https=)
DE (1) DE10237317B4 (https=)
WO (1) WO2004017988A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106604930A (zh) * 2014-05-30 2017-04-26 新英格兰生物实验室公司 去糖基化试剂和方法

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10237317B4 (de) * 2002-08-15 2010-04-08 3M Espe Ag Enzymhaltige Zusammensetzung, Verfahren zu deren Herstellung und deren Verwendung
EP1720661B1 (en) 2004-02-27 2008-12-24 3M Espe Ag Dose delivery system
EP1600141B1 (en) 2004-05-24 2013-04-17 3M Deutschland GmbH Collagenolytic active enzyme containing compositions for the treatment of dental caries
EP1634948A1 (en) 2004-09-10 2006-03-15 Basf Aktiengesellschaft Means and methods for preventing and/or treating caries
EP1754464A1 (en) * 2005-08-17 2007-02-21 3M Innovative Properties Company Enzyme comprising dental composition
EP1844727A1 (en) 2006-04-12 2007-10-17 3M Innovative Properties Company Dental instrument for removing solely unremineralisable carious dentin
EP2094830B1 (en) 2006-12-19 2013-04-10 Basf Se Uses and methods for preventing and/or treating caries caused by mutans streptococci
EP2139979B1 (en) 2007-03-27 2015-02-25 Novozymes A/S Stable enzyme solutions and method of manufacturing
USD588446S1 (en) * 2007-12-12 2009-03-17 Hashim Paul R Tree nail
WO2009100456A2 (en) * 2008-02-08 2009-08-13 Prothera, Inc. Inhibition and treatment of gastrointestinal biofilms
MX2012009705A (es) 2010-02-25 2012-12-17 Novozymes As Variantes de lisozima y polinucleotidos que codifican la misma.
WO2012035103A1 (en) 2010-09-16 2012-03-22 Novozymes A/S Lysozymes
RU2619051C2 (ru) 2011-11-25 2017-05-11 Новозимс А/С Полипептиды с лизоцимной активностью и полинуклеотиды, кодирующие их
ES2582802T3 (es) 2012-01-23 2016-09-15 Morphosys Ag Uso de lisozima como marcador
US11685911B2 (en) 2016-02-16 2023-06-27 Monaghan Mushroom S Group Fungal polypeptides having lysozyme activity
US10451599B2 (en) 2016-09-02 2019-10-22 Zepto Life Technology, LLC Methods of isolating and detecting metal ions from proteins
CN110621779B (zh) 2017-05-12 2024-05-14 诺维信公司 具有溶菌酶活性的多肽、编码其的多核苷酸以及其用途和组合物
US11571367B2 (en) * 2018-04-05 2023-02-07 Terrell F. Pannkuk Composition and method for endodontic debridement
EP4629838A1 (en) 2022-12-08 2025-10-15 Novozymes A/S Polypeptide having lysozyme activity and polynucleotides encoding same

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1265468A (en) * 1917-09-18 1918-05-07 Chresten Torben Madsen Level.
DE1467951A1 (de) * 1963-09-04 1969-02-13 Iptor Pharmazeutische Praepara Proteolytische Enzyme enthaltende Zahnreinigungsmittel
NL148236B (nl) * 1967-07-28 1976-01-15 Merck & Co Inc Werkwijze voor het bereiden van enzym bevattende tand- en mondverzorgingsmiddelen en aldus verkregen gevormde produkten.
BE755331A (fr) * 1969-09-01 1971-02-01 Blendax Werke Schneider Co Produits de soins buccaux et dentaires
DE2309440A1 (de) * 1973-02-26 1974-09-05 Katz Verfahren zum isolieren von lysozym
JPS56106593A (en) * 1980-01-24 1981-08-24 Dainippon Pharmaceut Co Ltd Alkali protease m3
JPS57142910A (en) 1981-02-28 1982-09-03 Sankin Kogyo Kk Water-soluble solid agent for cleaning artificial denture
US4355022A (en) * 1981-07-01 1982-10-19 Interon, Inc. Method of dental treatment
JPS58148828A (ja) * 1982-02-27 1983-09-05 Advance Res & Dev Co Ltd 歯根管処理剤並びに同処理用キツト
EP0115974B1 (fr) * 1983-01-05 1988-09-07 Institut Pasteur Préparation à activité collagénolytique ayant une activité élevée et compositions pharmaceutiques la contenant
US4693888A (en) * 1983-08-11 1987-09-15 Lion Corporation Caries-preventive composition
JPH024710A (ja) 1988-06-23 1990-01-09 Nippon Soda Co Ltd 感染根管及び根尖性歯周組織炎治療用製剤
FR2651433B1 (fr) * 1989-09-07 1994-01-14 Dominique Dana Complexe enzymatique a activite sur le tartre et la carie dentaire.
GB8926904D0 (en) * 1989-11-28 1990-01-17 Unilever Plc Thickening system
JP2566676B2 (ja) 1990-03-28 1996-12-25 株式会社クラレ 歯科用組成物
EP0514520A1 (en) 1990-12-05 1992-11-25 Warner-Lambert Company Enzyme containing denture cleanser
GB9207280D0 (en) * 1992-04-02 1992-05-13 Unilever Plc Skin care method and composition
SE9201628D0 (sv) 1992-05-22 1992-05-22 Phairson Medical Ab Pharmaceutical composition
JP3144102B2 (ja) 1992-12-08 2001-03-12 三菱マテリアル株式会社 歯牙根管消毒剤
US5386024A (en) * 1993-02-10 1995-01-31 Gen-Probe Incorporated Method to prepare nucleic acids from a biological sample using low pH and acid protease
JPH0769854A (ja) * 1993-09-02 1995-03-14 Lion Corp 義歯洗浄剤
JP3396934B2 (ja) * 1993-12-01 2003-04-14 ライオン株式会社 義歯洗浄剤
RU2083215C1 (ru) 1994-05-11 1997-07-10 Петр Григорьевич Сторожук Средство для лечения секреторной недостаточности желудка преимущественно у новорожденных детей - пепсирен
CA2199478A1 (en) * 1994-09-09 1996-03-14 Allan L. Delisle Bacteriophage-encoded enzymes for the treatment and prevention of dental caries and periodontal diseases
US5670132A (en) * 1994-09-20 1997-09-23 Immunomedics, Inc. Modified radioantibody fragments for reduced renal uptake
JPH11502527A (ja) * 1995-03-28 1999-03-02 ノボ ノルディスク アクティーゼルスカブ 口内ケア組成物
US5625341A (en) 1995-08-31 1997-04-29 Sensormatic Electronics Corporation Multi-bit EAS marker powered by interrogation signal in the eight MHz band
JP2000506845A (ja) 1996-03-06 2000-06-06 ノボ ノルディスク アクティーゼルスカブ 微生物細胞を死滅又は抑制する方法
CN1216463A (zh) 1996-04-16 1999-05-12 诺沃挪第克公司 祛除齿斑的组合物
SE507437C2 (sv) 1996-11-14 1998-06-08 Medi Team Dentalutveckling I G Preparat för användning vid kemisk-mekanisk behandling av kariesangrepp och förfarande för framställning av preparatet
US6287550B1 (en) * 1996-12-17 2001-09-11 The Procter & Gamble Company Animal care system and litter with reduced malodor impression
US6100080A (en) 1996-12-18 2000-08-08 Novo Nordisk A/S Method for enzymatic treatment of biofilm
US6090381A (en) * 1997-02-11 2000-07-18 Immunomedics, Inc. Stimulation of an immune response with antibodies labeled with the . .alpha-galactosyl epitope
AU2198097A (en) * 1997-03-07 1998-09-22 Procter & Gamble Company, The Cleaning compositions comprising xylan degrading alkaline enzyme and non-plant cell walls degrading enzyme
AU3799897A (en) * 1997-07-09 1999-02-08 Procter & Gamble Company, The Cleaning compositions comprising a specific oxygenase
DE29714246U1 (de) 1997-08-08 1998-12-10 THERA Patent GmbH & Co. KG Gesellschaft für industrielle Schutzrechte, 82229 Seefeld Vorrichtung zum Lagern und Auftragen einer fließfähigen Substanz
ATE238669T1 (de) 1998-11-09 2003-05-15 Novozymes As Antimikorbielle zusammensetzung, die eine oxidoreduktase und ein verstärkungsmittel vom n- hydroxyanilid-typ enthält
US6521215B2 (en) * 1999-05-28 2003-02-18 Devin Okay Compositions and methods for tooth treatment
JP4175746B2 (ja) * 1999-08-30 2008-11-05 独立行政法人科学技術振興機構 新規な耐熱性コラーゲン分解酵素、前記酵素を産生する新規な微生物および前記酵素の製造方法
DE19955746B4 (de) * 1999-11-19 2004-01-29 3M Espe Ag Oberflächenbehandlungsmittel für Hartgewebe und Verwendung von die Enzymaktivität begrenzenden Mitteln zu dessen Herstellung
DE10034647C1 (de) * 2000-07-14 2002-04-04 3M Espe Ag Verfahren zur Durchführung einer Speichelanalyse
JP2002078489A (ja) 2000-09-04 2002-03-19 Daiwa Kasei Kk セリン残基が活性発現に関与する新規酸性プロテアーゼ
DE10056212B4 (de) * 2000-11-13 2005-08-18 3M Espe Ag Vorrichtung zum Lagern und Ausbringen von fließfähigen Zusammensetzungen, Verfahren zur Herstellung und Verwendung der Vorrichtung
US7402416B2 (en) * 2002-05-10 2008-07-22 Colgate-Palmolive Company Antibacterial dentifrice exhibiting antiplaque and breath freshening properties
WO2004000222A2 (en) 2002-06-21 2003-12-31 New Horizons Diagnostics Corporation The use of bacterial phage associated lysing proteins for treating bacterial dental caries
DE10237317B4 (de) 2002-08-15 2010-04-08 3M Espe Ag Enzymhaltige Zusammensetzung, Verfahren zu deren Herstellung und deren Verwendung
AU2003285325A1 (en) 2002-11-22 2004-06-18 Unilever Plc Oral compositions comprising salts of alkyl hydroxybenzoates
US20040120901A1 (en) 2002-12-20 2004-06-24 Dong Wu Dental compositions including enzymes and methods
EP1600141B1 (en) * 2004-05-24 2013-04-17 3M Deutschland GmbH Collagenolytic active enzyme containing compositions for the treatment of dental caries
EP1754464A1 (en) * 2005-08-17 2007-02-21 3M Innovative Properties Company Enzyme comprising dental composition

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106604930A (zh) * 2014-05-30 2017-04-26 新英格兰生物实验室公司 去糖基化试剂和方法
CN106604930B (zh) * 2014-05-30 2021-10-29 新英格兰生物实验室公司 去糖基化试剂和方法

Also Published As

Publication number Publication date
JP2006501225A (ja) 2006-01-12
JP5087611B2 (ja) 2012-12-05
AU2003240667A1 (en) 2004-03-11
AU2003240667C1 (en) 2010-07-15
JP2010090164A (ja) 2010-04-22
JP4571859B2 (ja) 2010-10-27
AU2010201297B2 (en) 2012-12-13
EP1530481B1 (en) 2012-01-18
US9050332B2 (en) 2015-06-09
CA2490721A1 (en) 2004-03-04
DE10237317A1 (de) 2004-03-11
EP2314307B1 (en) 2014-03-12
DE10237317B4 (de) 2010-04-08
CN101810856B (zh) 2015-05-13
AU2010201297A1 (en) 2010-04-22
WO2004017988A1 (en) 2004-03-04
ATE541583T1 (de) 2012-02-15
EP2314307A1 (en) 2011-04-27
EP1530481A1 (en) 2005-05-18
US20060115436A1 (en) 2006-06-01
US20080213196A1 (en) 2008-09-04
CN101810856A (zh) 2010-08-25

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Open date: 20050928