CN1602194A - 反转录病毒感染的治疗方法 - Google Patents

反转录病毒感染的治疗方法 Download PDF

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Publication number
CN1602194A
CN1602194A CNA028216873A CN02821687A CN1602194A CN 1602194 A CN1602194 A CN 1602194A CN A028216873 A CNA028216873 A CN A028216873A CN 02821687 A CN02821687 A CN 02821687A CN 1602194 A CN1602194 A CN 1602194A
Authority
CN
China
Prior art keywords
oxide
pyridine
dimethylphenyl
sulfonyl
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA028216873A
Other languages
English (en)
Chinese (zh)
Inventor
J·A·莱卡迪
J·皮尔斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Uniroyal Chemical Co Inc
Original Assignee
Uniroyal Chemical Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniroyal Chemical Co Inc filed Critical Uniroyal Chemical Co Inc
Publication of CN1602194A publication Critical patent/CN1602194A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Quinoline Compounds (AREA)
CNA028216873A 2001-10-29 2002-10-03 反转录病毒感染的治疗方法 Pending CN1602194A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/021,453 2001-10-29
US10/021,453 US7064139B2 (en) 2001-10-29 2001-10-29 Method for treating retroviral infections

Publications (1)

Publication Number Publication Date
CN1602194A true CN1602194A (zh) 2005-03-30

Family

ID=21804307

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA028216873A Pending CN1602194A (zh) 2001-10-29 2002-10-03 反转录病毒感染的治疗方法

Country Status (8)

Country Link
US (3) US7064139B2 (enExample)
JP (1) JP2005515169A (enExample)
CN (1) CN1602194A (enExample)
AU (1) AU2002330239B2 (enExample)
BR (1) BR0213742A (enExample)
CA (1) CA2464303A1 (enExample)
MX (1) MXPA04004058A (enExample)
WO (1) WO2003037311A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108956809A (zh) * 2018-06-04 2018-12-07 四川科伦药物研究院有限公司 一种检测1-(1-氯乙基)-2,3-二甲苯有关物质的方法

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* Cited by examiner, † Cited by third party
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JP4090491B2 (ja) * 2003-12-23 2008-05-28 ハー・ルンドベック・アクチエゼルスカベット ２−（１ｈ−インドリルスルファニル）−ベンジルアミン誘導体
AR052308A1 (es) * 2004-07-16 2007-03-14 Lundbeck & Co As H Derivados de 2-(1h-indolilsulfanil)-arilamina y una composicion farmaceutica que contiene al compuesto
US7629473B2 (en) * 2005-06-17 2009-12-08 H. Lundbeck A/S 2-(1H-indolylsulfanyl)-aryl amine derivatives
AR054393A1 (es) * 2005-06-17 2007-06-20 Lundbeck & Co As H Derivados de benzo(b)furano y benzo(b)tiofeno, composiciones farmaceuticas que los contienen y su uso en la fabricacion de un medicamento para el tratamiento de enfermedades mediadas por la inhibicion de la reabsorcion de neurotransmisores de amina biogenicos.
EP2099298A4 (en) * 2006-12-07 2010-01-06 Helsinn Healthcare Sa CRYSTALLINE AND AMORPHOUS FORMS OF PALONOSETRON HYDROCHLORIDE
CN106674099A (zh) * 2016-12-22 2017-05-17 江苏燎原环保科技股份有限公司 一种二［2‑(n‑氧化物‑吡啶基‑2‑硫基)乙基］胺的制备方法
CN106674100A (zh) * 2016-12-22 2017-05-17 江苏燎原环保科技股份有限公司 一种三［2‑(n‑氧化物‑吡啶基‑2‑硫基)乙基］胺的制备方法

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GB1268772A (en) * 1968-03-15 1972-03-29 Glaxo Lab Ltd NOVEL alpha-CARBOLINE DERIVATIVES, THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME
US3960542A (en) * 1975-03-17 1976-06-01 Uniroyal Inc. Herbicidal 2-sulfinyl and 2-sulfonyl pyridine N-oxide derivatives
JPS52125170A (en) * 1976-04-12 1977-10-20 Yoshitomi Pharmaceut Ind Ltd Pyridine derivatives
GB2039218B (en) * 1978-11-30 1983-07-27 Wyeth John & Brother Ltd Pharmaceutical compositions
US4371537A (en) * 1981-08-13 1983-02-01 The Dow Chemical Company Sulfur-substituted phenoxypyridines having antiviral activity
US4616087A (en) * 1982-05-21 1986-10-07 The Dow Chemical Company 2,5-bis alkyl sulfonyl and 2,5-bis alkyl thio substituted-pyridines
US5268389A (en) * 1989-10-16 1993-12-07 Uniroyal Chemical Company, Inc. Thiocarboxylate ester compounds compositions containing the same
NZ240313A (en) * 1990-10-22 1994-04-27 Res Corp Technologies Inc Anti-retrovirus compositions containing aryl and heteroaryl derivatives
AU2395095A (en) * 1994-04-29 1995-11-29 G.D. Searle & Co. Method of using (h+/k+) atpase inhibitors as antiviral agents
FR2737496B1 (fr) * 1995-07-31 1997-12-19 Centre Nat Rech Scient 4-aryl-thio-pyridin-2(1h)-ones, medicaments les contenant et leurs utilisations dans le traitement de maladies liees aux vih 1 et 2
US5770613A (en) * 1995-09-29 1998-06-23 Geron Corporation Telomerase inhibitors
US5696151A (en) * 1995-11-30 1997-12-09 Uniroyal Chemical Company, Inc. Compounds useful for the inhibition of the replication of HIV-1 and HIV-1 mutants
EP0973513A4 (en) * 1996-10-23 2003-03-19 Zymogenetics Inc COMPILATIONS AND METHOD FOR TREATING BONE DEFICIENCY
ATE303993T1 (de) * 1997-12-22 2005-09-15 Pharmacia & Upjohn Co Llc 4-hydroxychinolin-3-carboxamide und hydrazide als antivirale wirkstoffe
JP2000302760A (ja) * 1999-02-17 2000-10-31 Hokuriku Seiyaku Co Ltd ２−メルカプトキノリン誘導体
CN1156471C (zh) * 1999-04-23 2004-07-07 武田药品工业株式会社 5-吡啶基-1,3-唑系化合物、它们的制备方法及用途
US6316472B1 (en) * 1999-05-13 2001-11-13 Merck Frosst Canada & Co. Heterosubstituted pyridine derivatives as PDE 4 inhibitors
JP2003528810A (ja) * 1999-08-04 2003-09-30 ミレニアム ファーマスーティカルズ インク メラノコルチン−４受容体結合化合物及びその使用方法
US6498254B1 (en) * 2001-10-29 2002-12-24 Uniroyal Chemical Company, Inc. Antiretroviral compounds and compositions

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108956809A (zh) * 2018-06-04 2018-12-07 四川科伦药物研究院有限公司 一种检测1-(1-氯乙基)-2,3-二甲苯有关物质的方法
CN108956809B (zh) * 2018-06-04 2021-03-23 四川科伦药物研究院有限公司 一种检测1-(1-氯乙基)-2,3-二甲苯有关物质的方法

Also Published As

Publication number Publication date
US20040132778A1 (en) 2004-07-08
BR0213742A (pt) 2006-05-23
CA2464303A1 (en) 2003-05-08
AU2002330239B2 (en) 2008-06-26
US20040204451A1 (en) 2004-10-14
WO2003037311A2 (en) 2003-05-08
MXPA04004058A (es) 2004-09-06
US7064139B2 (en) 2006-06-20
US20030139445A1 (en) 2003-07-24
WO2003037311A3 (en) 2003-10-16
JP2005515169A (ja) 2005-05-26

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Open date: 20050330