CA2464303A1 - Method for treating retroviral infections - Google Patents

Method for treating retroviral infections Download PDF

Info

Publication number
CA2464303A1
CA2464303A1 CA002464303A CA2464303A CA2464303A1 CA 2464303 A1 CA2464303 A1 CA 2464303A1 CA 002464303 A CA002464303 A CA 002464303A CA 2464303 A CA2464303 A CA 2464303A CA 2464303 A1 CA2464303 A1 CA 2464303A1
Authority
CA
Canada
Prior art keywords
oxide
pyridine
dimethylphenyl
methylsulfonyl
sulfonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002464303A
Other languages
English (en)
French (fr)
Inventor
John A. Lacadie
James Pierce
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Uniroyal Chemical Co Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2464303A1 publication Critical patent/CA2464303A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Quinoline Compounds (AREA)
CA002464303A 2001-10-29 2002-10-03 Method for treating retroviral infections Abandoned CA2464303A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/021,453 US7064139B2 (en) 2001-10-29 2001-10-29 Method for treating retroviral infections
US10/021,453 2001-10-29
PCT/US2002/031836 WO2003037311A2 (en) 2001-10-29 2002-10-03 Method for treating retroviral infections

Publications (1)

Publication Number Publication Date
CA2464303A1 true CA2464303A1 (en) 2003-05-08

Family

ID=21804307

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002464303A Abandoned CA2464303A1 (en) 2001-10-29 2002-10-03 Method for treating retroviral infections

Country Status (8)

Country Link
US (3) US7064139B2 (enExample)
JP (1) JP2005515169A (enExample)
CN (1) CN1602194A (enExample)
AU (1) AU2002330239B2 (enExample)
BR (1) BR0213742A (enExample)
CA (1) CA2464303A1 (enExample)
MX (1) MXPA04004058A (enExample)
WO (1) WO2003037311A2 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1701940E (pt) * 2003-12-23 2008-07-30 Lundbeck & Co As H Derivados de 2-(1h-indolilsulfanil)-benzil-amina como ssri
AR052308A1 (es) * 2004-07-16 2007-03-14 Lundbeck & Co As H Derivados de 2-(1h-indolilsulfanil)-arilamina y una composicion farmaceutica que contiene al compuesto
US7629473B2 (en) * 2005-06-17 2009-12-08 H. Lundbeck A/S 2-(1H-indolylsulfanyl)-aryl amine derivatives
AR054393A1 (es) * 2005-06-17 2007-06-20 Lundbeck & Co As H Derivados de benzo(b)furano y benzo(b)tiofeno, composiciones farmaceuticas que los contienen y su uso en la fabricacion de un medicamento para el tratamiento de enfermedades mediadas por la inhibicion de la reabsorcion de neurotransmisores de amina biogenicos.
EP2099298A4 (en) * 2006-12-07 2010-01-06 Helsinn Healthcare Sa CRYSTALLINE AND AMORPHOUS FORMS OF PALONOSETRON HYDROCHLORIDE
CN106674100A (zh) * 2016-12-22 2017-05-17 江苏燎原环保科技股份有限公司 一种三［2‑(n‑氧化物‑吡啶基‑2‑硫基)乙基］胺的制备方法
CN106674099A (zh) * 2016-12-22 2017-05-17 江苏燎原环保科技股份有限公司 一种二［2‑(n‑氧化物‑吡啶基‑2‑硫基)乙基］胺的制备方法
CN108956809B (zh) * 2018-06-04 2021-03-23 四川科伦药物研究院有限公司 一种检测1-(1-氯乙基)-2,3-二甲苯有关物质的方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1268772A (en) * 1968-03-15 1972-03-29 Glaxo Lab Ltd NOVEL alpha-CARBOLINE DERIVATIVES, THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME
US3960542A (en) * 1975-03-17 1976-06-01 Uniroyal Inc. Herbicidal 2-sulfinyl and 2-sulfonyl pyridine N-oxide derivatives
JPS52125170A (en) * 1976-04-12 1977-10-20 Yoshitomi Pharmaceut Ind Ltd Pyridine derivatives
GB2039218B (en) * 1978-11-30 1983-07-27 Wyeth John & Brother Ltd Pharmaceutical compositions
US4371537A (en) * 1981-08-13 1983-02-01 The Dow Chemical Company Sulfur-substituted phenoxypyridines having antiviral activity
US4616087A (en) * 1982-05-21 1986-10-07 The Dow Chemical Company 2,5-bis alkyl sulfonyl and 2,5-bis alkyl thio substituted-pyridines
US5268389A (en) * 1989-10-16 1993-12-07 Uniroyal Chemical Company, Inc. Thiocarboxylate ester compounds compositions containing the same
WO1992006683A1 (en) * 1990-10-22 1992-04-30 Research Corporation Technologies, Inc. Aryl and heteroaryl compounds having anti-retrovirus activity
US5945425A (en) * 1994-04-29 1999-08-31 G.D. Searle & Co. Method of using (H+ /K+)ATPase inhibitors as antiviral agents
FR2737496B1 (fr) * 1995-07-31 1997-12-19 Centre Nat Rech Scient 4-aryl-thio-pyridin-2(1h)-ones, medicaments les contenant et leurs utilisations dans le traitement de maladies liees aux vih 1 et 2
US5770613A (en) * 1995-09-29 1998-06-23 Geron Corporation Telomerase inhibitors
US5696151A (en) * 1995-11-30 1997-12-09 Uniroyal Chemical Company, Inc. Compounds useful for the inhibition of the replication of HIV-1 and HIV-1 mutants
EP0973513A4 (en) * 1996-10-23 2003-03-19 Zymogenetics Inc COMPILATIONS AND METHOD FOR TREATING BONE DEFICIENCY
NZ505362A (en) * 1997-12-22 2004-12-24 Upjohn Co 4-hydroxyquinoline-3-carboxamides and -hydrazides useful as antiviral agents
JP2000302760A (ja) * 1999-02-17 2000-10-31 Hokuriku Seiyaku Co Ltd ２−メルカプトキノリン誘導体
MXPA01010675A (es) * 1999-04-23 2002-06-04 Takeda Chemical Industries Ltd Compuestos de 5-piridil-1, 3-azol, proceso para su produccion y uso de los mismos.
US6316472B1 (en) * 1999-05-13 2001-11-13 Merck Frosst Canada & Co. Heterosubstituted pyridine derivatives as PDE 4 inhibitors
MXPA02001160A (es) * 1999-08-04 2002-07-02 Millennium Pharm Inc Compuestos que se unen a los receptores para melanocortina-4, y metodo de uso de estos.
US6498254B1 (en) * 2001-10-29 2002-12-24 Uniroyal Chemical Company, Inc. Antiretroviral compounds and compositions

Also Published As

Publication number Publication date
CN1602194A (zh) 2005-03-30
US20040132778A1 (en) 2004-07-08
AU2002330239B2 (en) 2008-06-26
WO2003037311A3 (en) 2003-10-16
US20030139445A1 (en) 2003-07-24
JP2005515169A (ja) 2005-05-26
MXPA04004058A (es) 2004-09-06
WO2003037311A2 (en) 2003-05-08
US7064139B2 (en) 2006-06-20
US20040204451A1 (en) 2004-10-14
BR0213742A (pt) 2006-05-23

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued