CN1471507A - 用于制备加巴喷丁中间体的改进方法 - Google Patents
用于制备加巴喷丁中间体的改进方法 Download PDFInfo
- Publication number
- CN1471507A CN1471507A CNA018181899A CN01818189A CN1471507A CN 1471507 A CN1471507 A CN 1471507A CN A018181899 A CNA018181899 A CN A018181899A CN 01818189 A CN01818189 A CN 01818189A CN 1471507 A CN1471507 A CN 1471507A
- Authority
- CN
- China
- Prior art keywords
- reaction
- prepared according
- ammonium hydroxide
- product prepared
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/86—Oxygen atoms
- C07D211/88—Oxygen atoms attached in positions 2 and 6, e.g. glutarimide
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24489100P | 2000-11-02 | 2000-11-02 | |
| US60/244,891 | 2000-11-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1471507A true CN1471507A (zh) | 2004-01-28 |
Family
ID=22924517
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA018181899A Pending CN1471507A (zh) | 2000-11-02 | 2001-10-26 | 用于制备加巴喷丁中间体的改进方法 |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US6613904B2 (enExample) |
| EP (1) | EP1337506A4 (enExample) |
| JP (1) | JP2004530637A (enExample) |
| KR (1) | KR20030048105A (enExample) |
| CN (1) | CN1471507A (enExample) |
| AU (1) | AU2002213506A1 (enExample) |
| CA (1) | CA2427237A1 (enExample) |
| CZ (1) | CZ20031432A3 (enExample) |
| DE (1) | DE01981893T1 (enExample) |
| ES (1) | ES2209674T1 (enExample) |
| HR (1) | HRP20030443A2 (enExample) |
| HU (1) | HUP0303352A3 (enExample) |
| IL (1) | IL155733A0 (enExample) |
| IS (1) | IS6799A (enExample) |
| MX (1) | MXPA03003899A (enExample) |
| NO (1) | NO20031927L (enExample) |
| PL (1) | PL365569A1 (enExample) |
| SK (1) | SK6372003A3 (enExample) |
| WO (1) | WO2002036545A1 (enExample) |
| YU (1) | YU33303A (enExample) |
| ZA (1) | ZA200303349B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007019752A1 (en) * | 2005-08-19 | 2007-02-22 | Nhwa Pharma. Corporation | Process for the preparation of gabapentin hydrochloride |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050004219A1 (en) * | 2003-07-01 | 2005-01-06 | Medtronic, Inc. | Pump systems including injectable gabapentin compositions |
| US20050090548A1 (en) * | 2003-10-23 | 2005-04-28 | Medtronic, Inc. | Intrathecal gabapentin for treatment of epilepsy |
| US20050090549A1 (en) * | 2003-10-23 | 2005-04-28 | Medtronic, Inc. | Intrathecal gabapentin for treatment of pain |
| US20050187295A1 (en) * | 2004-02-19 | 2005-08-25 | Surendra Kalyan | Processes for the preparation of gabapentin |
| ITMI20040501A1 (it) * | 2004-03-17 | 2004-06-17 | Caffaro Spa Ind Chim | Procedimento per la preparazione della monoaamide dell'acrido ciclosendiacetico |
| ITMI20041271A1 (it) * | 2004-06-24 | 2004-09-24 | Zambon Spa | Processo di preparazione di gabapentina |
| US8495974B2 (en) | 2009-05-18 | 2013-07-30 | Vito Agosta | Fuel system and method for burning liquid ammonia in engines and boilers |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1142168B (de) * | 1959-07-01 | 1963-01-10 | Warner Lambert Pharmaceutical | Verfahren zur Herstellung von ª‰,ª‰-Penta-methylenbutyrolacton bzw. Salzen der 3, 3-Pentamethylen-4-hydroxybuttersaeure |
| DE2460891C2 (de) | 1974-12-21 | 1982-09-23 | Gödecke AG, 1000 Berlin | 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
| DE3928182A1 (de) * | 1989-08-25 | 1991-02-28 | Goedecke Ag | Verfahren zur herstellung von gabapentin |
| PL185991B1 (pl) | 1996-03-14 | 2003-09-30 | Warner Lambert Co | Nowe podstawione cykliczne aminokwasy i kompozycja farmaceutyczna |
-
2001
- 2001-10-26 CA CA002427237A patent/CA2427237A1/en not_active Abandoned
- 2001-10-26 PL PL01365569A patent/PL365569A1/xx not_active Application Discontinuation
- 2001-10-26 SK SK637-2003A patent/SK6372003A3/sk unknown
- 2001-10-26 JP JP2002539305A patent/JP2004530637A/ja not_active Withdrawn
- 2001-10-26 US US09/984,058 patent/US6613904B2/en not_active Expired - Fee Related
- 2001-10-26 MX MXPA03003899A patent/MXPA03003899A/es active IP Right Grant
- 2001-10-26 AU AU2002213506A patent/AU2002213506A1/en not_active Abandoned
- 2001-10-26 HR HR20030443A patent/HRP20030443A2/hr not_active Application Discontinuation
- 2001-10-26 IL IL15573301A patent/IL155733A0/xx unknown
- 2001-10-26 WO PCT/US2001/042783 patent/WO2002036545A1/en not_active Ceased
- 2001-10-26 CZ CZ20031432A patent/CZ20031432A3/cs unknown
- 2001-10-26 DE DE0001337506T patent/DE01981893T1/de active Pending
- 2001-10-26 KR KR10-2003-7006056A patent/KR20030048105A/ko not_active Ceased
- 2001-10-26 ES ES01981893T patent/ES2209674T1/es active Pending
- 2001-10-26 CN CNA018181899A patent/CN1471507A/zh active Pending
- 2001-10-26 HU HU0303352A patent/HUP0303352A3/hu unknown
- 2001-10-26 YU YU33303A patent/YU33303A/sh unknown
- 2001-10-26 EP EP01981893A patent/EP1337506A4/en not_active Withdrawn
-
2003
- 2003-04-29 NO NO20031927A patent/NO20031927L/no not_active Application Discontinuation
- 2003-04-30 IS IS6799A patent/IS6799A/is unknown
- 2003-04-30 ZA ZA200303349A patent/ZA200303349B/en unknown
- 2003-06-06 US US10/455,314 patent/US6881843B2/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007019752A1 (en) * | 2005-08-19 | 2007-02-22 | Nhwa Pharma. Corporation | Process for the preparation of gabapentin hydrochloride |
| US7667071B2 (en) | 2005-08-19 | 2010-02-23 | Nhwa Pharma Corporation | Process for the preparation of gabapentin hydrochloride |
Also Published As
| Publication number | Publication date |
|---|---|
| US20030195358A1 (en) | 2003-10-16 |
| CZ20031432A3 (cs) | 2003-12-17 |
| US6613904B2 (en) | 2003-09-02 |
| HUP0303352A3 (en) | 2005-04-28 |
| NO20031927D0 (no) | 2003-04-29 |
| EP1337506A4 (en) | 2005-05-04 |
| HUP0303352A2 (hu) | 2004-01-28 |
| WO2002036545A1 (en) | 2002-05-10 |
| CA2427237A1 (en) | 2002-05-10 |
| IS6799A (is) | 2003-04-30 |
| PL365569A1 (en) | 2005-01-10 |
| SK6372003A3 (en) | 2003-12-02 |
| EP1337506A1 (en) | 2003-08-27 |
| MXPA03003899A (es) | 2005-02-17 |
| JP2004530637A (ja) | 2004-10-07 |
| YU33303A (sh) | 2006-05-25 |
| KR20030048105A (ko) | 2003-06-18 |
| DE01981893T1 (de) | 2004-05-19 |
| IL155733A0 (en) | 2003-11-23 |
| HRP20030443A2 (en) | 2005-04-30 |
| US20020107395A1 (en) | 2002-08-08 |
| ZA200303349B (en) | 2005-06-09 |
| AU2002213506A1 (en) | 2002-05-15 |
| ES2209674T1 (es) | 2004-07-01 |
| NO20031927L (no) | 2003-04-29 |
| US6881843B2 (en) | 2005-04-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |