CN1376070A - 用于治疗子宫内膜组织子宫外增生、慢性骨盆疼痛和输卵管梗阻的方法 - Google Patents

用于治疗子宫内膜组织子宫外增生、慢性骨盆疼痛和输卵管梗阻的方法 Download PDF

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Publication number
CN1376070A
CN1376070A CN00813196A CN00813196A CN1376070A CN 1376070 A CN1376070 A CN 1376070A CN 00813196 A CN00813196 A CN 00813196A CN 00813196 A CN00813196 A CN 00813196A CN 1376070 A CN1376070 A CN 1376070A
Authority
CN
China
Prior art keywords
antagonist
administered
short
lhrh antagonist
lhrh
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN00813196A
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English (en)
Chinese (zh)
Inventor
J·恩格尔
H·利瑟穆勒-温赞
R·费尔比尔保穆
K·狄德里啻
W·库皮克尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aeterna Zentaris GmbH
Original Assignee
Zentaris AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zentaris AG filed Critical Zentaris AG
Publication of CN1376070A publication Critical patent/CN1376070A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/09Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06Antiabortive agents; Labour repressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/02Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A61P5/04Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A61P5/08Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26Androgens

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN00813196A 1999-09-23 2000-09-20 用于治疗子宫内膜组织子宫外增生、慢性骨盆疼痛和输卵管梗阻的方法 Pending CN1376070A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15547899P 1999-09-23 1999-09-23
US60/155,478 1999-09-23

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CNA2007100789192A Division CN101045155A (zh) 1999-09-23 2000-09-20 用于治疗子宫内膜组织子宫外增生、慢性骨盆疼痛和输卵管梗阻的方法

Publications (1)

Publication Number Publication Date
CN1376070A true CN1376070A (zh) 2002-10-23

Family

ID=22555601

Family Applications (2)

Application Number Title Priority Date Filing Date
CN00813196A Pending CN1376070A (zh) 1999-09-23 2000-09-20 用于治疗子宫内膜组织子宫外增生、慢性骨盆疼痛和输卵管梗阻的方法
CNA2007100789192A Pending CN101045155A (zh) 1999-09-23 2000-09-20 用于治疗子宫内膜组织子宫外增生、慢性骨盆疼痛和输卵管梗阻的方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
CNA2007100789192A Pending CN101045155A (zh) 1999-09-23 2000-09-20 用于治疗子宫内膜组织子宫外增生、慢性骨盆疼痛和输卵管梗阻的方法

Country Status (22)

Country Link
EP (1) EP1214086A2 (https=)
JP (2) JP2003509467A (https=)
KR (1) KR100772852B1 (https=)
CN (2) CN1376070A (https=)
AU (1) AU769482B2 (https=)
BG (1) BG66128B1 (https=)
BR (1) BR0014198A (https=)
CA (1) CA2383510A1 (https=)
HK (1) HK1049117A1 (https=)
HU (1) HUP0202741A3 (https=)
IL (1) IL148185A0 (https=)
MX (1) MXPA02002436A (https=)
NO (1) NO331198B1 (https=)
NZ (1) NZ534836A (https=)
PL (1) PL201898B1 (https=)
RU (1) RU2255759C2 (https=)
SK (1) SK3752002A3 (https=)
TR (1) TR200200738T2 (https=)
TW (1) TWI267373B (https=)
UA (1) UA73956C2 (https=)
WO (1) WO2001021194A2 (https=)
ZA (1) ZA200201374B (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10157628A1 (de) * 2001-11-26 2003-06-12 Zentaris Ag Injektionslösung eines LHRH-Antagonisten
US7214662B2 (en) 2001-11-27 2007-05-08 Zentaris Gmbh Injectable solution of an LHRH antagonist
PT2252627T (pt) 2008-01-24 2017-07-24 Esperance Pharmaceuticals Constructos de fusão de domínio lítico e métodos para produzir e utilizar os mesmos
US20120053122A1 (en) * 2009-01-22 2012-03-01 Maatschap Interne Geneeskunde Rijnstate Method for the prophylaxis or treatment of flushing
AU2013337926B2 (en) 2012-10-30 2017-12-21 Esperance Pharmaceuticals, Inc. Antibody/drug conjugates and methods of use
US10881659B2 (en) 2013-03-15 2021-01-05 Abbvie Inc. Methods of treating heavy menstrual bleeding
US12083227B2 (en) 2017-08-18 2024-09-10 Abbvie Inc. Solid pharmaceutical formulations for treating endometriosis, uterine fibroids, polycystic ovary syndrome or adenomyosis
MX2020001877A (es) 2017-08-18 2020-09-14 Abbvie Inc Formulaciones farmacéuticas para tratar la endometriosis, los fibromas uterinos, el síndrome de ovario poliquístico o la adenomiosis.
CN112261942A (zh) 2018-04-19 2021-01-22 艾伯维公司 治疗重度月经出血的方法
EP3560555A1 (en) * 2018-04-26 2019-10-30 LifeArc A composition for treating one or more estrogen related diseases

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5064939A (en) * 1990-02-06 1991-11-12 The Salk Institute For Biological Studies Cyclic gnrh antagonists
SE9301606D0 (sv) * 1993-05-07 1993-05-07 Per-Christer Oden Composition for the treatment of impaired hair growth
IL114655A (en) * 1994-07-22 2005-08-31 Hampton Roads Medical College USE OF GnRH ANTAGONIST IN THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF A GONADAL-STEROID DEPENDENT CONDITION IN A MAMMAL
US5658884A (en) * 1994-07-22 1997-08-19 The Medical College Of Hampton Roads Establishment of tonic ovarian estrogen secretion for extended therapeutic regimens
DE19513662A1 (de) * 1995-04-08 1996-10-10 Schering Ag Pharmazeutisches Kombinationspräparat zur hormonalen Kontrazeption
DE19604231A1 (de) * 1996-01-29 1997-07-31 Schering Ag Pharmazeutisches Kombinationspräparat und seine Verwendung zur Behandlung von gynäkologischen Störungen
RU2108583C1 (ru) * 1996-07-29 1998-04-10 Николай Владимирович Рымашевский Способ определения показаний к проведению гормонотерапии у больных генитальным эндометриозом
WO1998009645A1 (en) * 1996-09-04 1998-03-12 Dott Research Laboratory Peptide-containing drug compositions for oral administration
WO1998055470A1 (en) * 1997-06-05 1998-12-10 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
DE19911771B4 (de) * 1999-03-17 2006-03-30 Zentaris Gmbh LHRH-Antagonist, Verfahren zu seiner Herstellung und seiner Verwendung

Also Published As

Publication number Publication date
CA2383510A1 (en) 2001-03-29
NO20021430D0 (no) 2002-03-21
RU2255759C2 (ru) 2005-07-10
BG66128B1 (bg) 2011-06-30
NO20021430L (no) 2002-05-07
NO331198B1 (no) 2011-10-31
TWI267373B (en) 2006-12-01
WO2001021194A2 (en) 2001-03-29
JP2012051920A (ja) 2012-03-15
JP2003509467A (ja) 2003-03-11
HUP0202741A3 (en) 2003-12-29
PL201898B1 (pl) 2009-05-29
TR200200738T2 (tr) 2002-08-21
KR20020035879A (ko) 2002-05-15
KR100772852B1 (ko) 2007-11-02
EP1214086A2 (en) 2002-06-19
IL148185A0 (en) 2002-09-12
WO2001021194A3 (en) 2002-03-14
AU769482B2 (en) 2004-01-29
NZ534836A (en) 2007-07-27
HK1049117A1 (zh) 2003-05-02
PL353244A1 (en) 2003-11-03
CN101045155A (zh) 2007-10-03
ZA200201374B (en) 2002-10-30
UA73956C2 (en) 2005-10-17
AU7779200A (en) 2001-04-24
BR0014198A (pt) 2002-05-21
HUP0202741A2 (hu) 2003-01-28
BG106584A (bg) 2003-02-28
MXPA02002436A (es) 2003-02-12
SK3752002A3 (en) 2003-06-03

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