CN1294517A - 具有合成可变区和修饰特异性的免疫球蛋白分子 - Google Patents
具有合成可变区和修饰特异性的免疫球蛋白分子 Download PDFInfo
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3046—Stomach, Intestines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/18—Kallidins; Bradykinins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2318/00—Antibody mimetics or scaffolds
- C07K2318/10—Immunoglobulin or domain(s) thereof as scaffolds for inserted non-Ig peptide sequences, e.g. for vaccination purposes
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
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- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
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- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cell Biology (AREA)
- AIDS & HIV (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
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| Application Number | Priority Date | Filing Date | Title |
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| US60/065,716 | 1997-11-14 | ||
| US8140398P | 1998-04-10 | 1998-04-10 | |
| US60/081,403 | 1998-04-10 |
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| CN1294517A true CN1294517A (zh) | 2001-05-09 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN98813117A Pending CN1294517A (zh) | 1997-11-14 | 1998-11-13 | 具有合成可变区和修饰特异性的免疫球蛋白分子 |
| CN98813119A Pending CN1327388A (zh) | 1997-11-14 | 1998-11-13 | 诱导抗独特型反应增强的修饰抗体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
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| CN98813119A Pending CN1327388A (zh) | 1997-11-14 | 1998-11-13 | 诱导抗独特型反应增强的修饰抗体 |
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| EP (2) | EP1032420A4 (pt) |
| JP (2) | JP2001526021A (pt) |
| KR (2) | KR20010015818A (pt) |
| CN (2) | CN1294517A (pt) |
| AU (2) | AU763029B2 (pt) |
| BR (2) | BR9815580A (pt) |
| CA (2) | CA2309990A1 (pt) |
| IL (2) | IL136113A0 (pt) |
| WO (2) | WO1999025379A1 (pt) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101970500B (zh) * | 2008-03-12 | 2013-08-14 | 伊姆克罗尼责任有限公司 | 抗tyrp1抗体 |
| CN103275914A (zh) * | 2013-06-03 | 2013-09-04 | 中国人民解放军军事医学科学院微生物流行病研究所 | 展示保护性抗原的细菌菌蜕及其应用 |
| CN101663321B (zh) * | 2006-08-28 | 2014-10-08 | 协和发酵麒麟株式会社 | 拮抗型人light特异性人源性单克隆抗体 |
| CN105263953A (zh) * | 2014-01-15 | 2016-01-20 | 勃林格殷格翰动物保健公司 | 猪细小病毒5a、使用方法及疫苗 |
| CN107073089A (zh) * | 2014-05-19 | 2017-08-18 | 瓦洛治疗公司 | 用于癌症疫苗的包被的溶瘤腺病毒 |
| CN111978382A (zh) * | 2020-09-03 | 2020-11-24 | 吉林大学第一医院 | 一种球形孢子丝菌Gp70重组蛋白的制备方法及其应用 |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003535021A (ja) * | 1998-11-13 | 2003-11-25 | ユーロ−セルティーク，エス．エイ． | 抗体ワクチン避妊薬 |
| DK1092779T3 (da) * | 1999-10-11 | 2010-02-15 | Pasteur Institut | Lentiviirusvektorer til fremstilling af immunterapeutiske præparater |
| WO2001088159A2 (en) * | 2000-05-16 | 2001-11-22 | Euro-Celtique S.A. | Cd28 synthebody for the modulation of immune responses |
| US7396917B2 (en) | 2000-12-05 | 2008-07-08 | Alexion Pharmaceuticals, Inc. | Rationally designed antibodies |
| DE60118023T2 (de) | 2000-12-05 | 2006-12-28 | Alexion Pharmaceuticals, Inc., Cheshire | Rationell entworfene antikörper |
| GB0103174D0 (en) * | 2001-02-08 | 2001-03-28 | Smithkline Beecham Plc | Novel method of treatment |
| AU2002307064A1 (en) * | 2001-04-02 | 2002-10-15 | Purdue Pharma L.P. | Immunoglobulin construct containing anti-mucin variable domain sequences for eliciting an anti-idiotype anti-tumor response |
| AU2002365926A1 (en) * | 2001-10-25 | 2003-09-02 | Euro-Celtique S.A. | Compositions and methods directed to anthrax toxin |
| ES2301794T3 (es) * | 2002-04-09 | 2008-07-01 | The Curators Of The University Of Missouri | Tratamiento de la diabetes de tipo 1, antes y despues de la expresion de marcadores de predisposicion. |
| IL165256A0 (en) | 2002-05-24 | 2005-12-18 | Schering Corp | Neutralizing human anti-igfr antibody |
| AR040778A1 (es) | 2002-08-06 | 2005-04-20 | Glaxo Group Ltd | Anticuerpos alterados o fragmentos funcionales que se unen a mag (glicoproteina asociada a mielina). |
| AU2003287345A1 (en) | 2002-10-31 | 2004-06-07 | Genentech, Inc. | Methods and compositions for increasing antibody production |
| GB0306309D0 (en) | 2003-03-19 | 2003-04-23 | Glaxo Group Ltd | Method of treatment |
| WO2005021595A1 (en) * | 2003-08-28 | 2005-03-10 | Euro-Celtique S.A. | Methods of antibody engineering using antibody display rules |
| JP2007510434A (ja) | 2003-11-12 | 2007-04-26 | シェーリング コーポレイション | 多重遺伝子発現のためのプラスミドシステム |
| AR046639A1 (es) | 2003-11-21 | 2005-12-14 | Schering Corp | Combinaciones terapeuticas de anticuerpo anti- igfr1 |
| WO2005084708A1 (ja) * | 2004-03-09 | 2005-09-15 | Kyoto University | Ｃｘｃｒ３阻害剤を含有する医薬組成物 |
| ATE493442T1 (de) | 2004-12-03 | 2011-01-15 | Schering Corp | Biologische marker zur vorauswahl von patienten für die anti-igf1r-therapie |
| GB0706070D0 (en) | 2007-03-28 | 2007-05-09 | Scancell Ltd | Nucleic acids |
| AU2010241706B2 (en) * | 2009-04-29 | 2015-07-09 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | ERG monoclonal antibodies |
| CN102816240B (zh) * | 2011-03-08 | 2014-02-12 | 中国人民解放军第三军医大学第二附属医院 | 一种融合蛋白及其融合蛋白表达载体 |
| EP2714083A4 (en) * | 2011-05-27 | 2015-03-04 | Fox Chase Cancer Ct | RATIONAL-DESIGNED TYPE II RECEPTOR ANTIBODIES WITH A MULLERIAN-INHIBITABLE SUBSTANCE |
| US9902760B2 (en) * | 2011-11-23 | 2018-02-27 | Bioven 3 Limited | Recombinant proteins and their therapeutic uses |
| JP5437525B1 (ja) | 2012-12-28 | 2014-03-12 | 株式会社ナード研究所 | チロシン誘導体およびチロシン誘導体の製造方法 |
| JP6549560B2 (ja) * | 2013-05-14 | 2019-07-24 | 上海 ハイチャーム インコーポレーテッドＳｈａｎｇｈａｉ Ｈｙｃｈａｒｍ Ｉｎｃ． | 低免疫原性タンパク質に対するエピトープワクチンおよびその製造方法と使用 |
| CN105693859B (zh) * | 2016-03-22 | 2019-06-21 | 苏州莱泰生物科技有限公司 | 抗人g2a单克隆抗体以及检测人巨噬细胞g2a表达量的试剂盒 |
| CN112646029B (zh) * | 2020-12-30 | 2022-07-29 | 深圳清华大学研究院 | 成熟脑源性神经营养因子的抗体及其应用和诊断试剂盒 |
| CN115856296B (zh) * | 2022-12-16 | 2023-07-25 | 华北理工大学 | 抗志贺氏菌的单克隆抗体及其检测中的应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5688657A (en) * | 1988-03-31 | 1997-11-18 | International Bio-Immune Systems, Inc. | Monoclonal antibodies against human colon carcinoma-associated antigens and uses therefor |
| JP3355351B2 (ja) * | 1989-02-24 | 2002-12-09 | ユーロジェン・ホールディング・ソシエテ・アノニム | 遺伝的に工作されたイムノグロブリン |
| GB9019553D0 (en) * | 1990-09-07 | 1990-10-24 | Unilever Plc | Specific binding agents |
| GB9109645D0 (en) * | 1991-05-03 | 1991-06-26 | Celltech Ltd | Recombinant antibodies |
| GB9223084D0 (en) * | 1992-11-04 | 1992-12-16 | Imp Cancer Res Tech | Compounds to target cells |
| CA2149529C (en) * | 1992-11-16 | 2006-05-02 | Fernado J. R. Do Couto | Peptides and anti-sense peptides with broad neoplastic specificity |
| WO1994014848A1 (en) * | 1992-12-24 | 1994-07-07 | The Regents Of The University Of California | Genetically engineered immunoglobulins |
| WO1994014847A1 (en) * | 1992-12-24 | 1994-07-07 | The Regents Of The University Of California | Genetically engineered immunoglobulins |
| US5476784A (en) * | 1993-04-06 | 1995-12-19 | Rice; Peter A. | Gonococcal anti-idiotypic antibodies and methods and compositions using them |
| US5653977A (en) * | 1993-09-09 | 1997-08-05 | Uab Research Foundation | Anti-idiotypic antibody that mimics the GD2 antigen |
| US5624904A (en) * | 1993-11-17 | 1997-04-29 | Massachusetts Institute Of Technology | Method for treating gram positive septicemia |
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1998
- 1998-11-13 CA CA002309990A patent/CA2309990A1/en not_active Abandoned
- 1998-11-13 JP JP2000520811A patent/JP2001526021A/ja active Pending
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- 1998-11-13 KR KR1020007005263A patent/KR20010015817A/ko not_active Application Discontinuation
- 1998-11-13 EP EP98958583A patent/EP1032420A4/en not_active Withdrawn
- 1998-11-13 EP EP98958584A patent/EP1030684A4/en not_active Withdrawn
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- 1998-11-13 WO PCT/US1998/024303 patent/WO1999025379A1/en not_active Application Discontinuation
- 1998-11-13 IL IL13611498A patent/IL136114A0/xx unknown
- 1998-11-13 CN CN98813117A patent/CN1294517A/zh active Pending
- 1998-11-13 CN CN98813119A patent/CN1327388A/zh active Pending
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- 1998-11-13 WO PCT/US1998/024302 patent/WO1999025378A1/en not_active Application Discontinuation
- 1998-11-13 JP JP2000520812A patent/JP2002507544A/ja active Pending
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2003
- 2003-10-10 AU AU2003252902A patent/AU2003252902A1/en not_active Abandoned
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101663321B (zh) * | 2006-08-28 | 2014-10-08 | 协和发酵麒麟株式会社 | 拮抗型人light特异性人源性单克隆抗体 |
| CN101970500B (zh) * | 2008-03-12 | 2013-08-14 | 伊姆克罗尼责任有限公司 | 抗tyrp1抗体 |
| CN103275914A (zh) * | 2013-06-03 | 2013-09-04 | 中国人民解放军军事医学科学院微生物流行病研究所 | 展示保护性抗原的细菌菌蜕及其应用 |
| CN103275914B (zh) * | 2013-06-03 | 2015-04-01 | 中国人民解放军军事医学科学院微生物流行病研究所 | 展示保护性抗原的细菌菌蜕及其应用 |
| CN105263953A (zh) * | 2014-01-15 | 2016-01-20 | 勃林格殷格翰动物保健公司 | 猪细小病毒5a、使用方法及疫苗 |
| CN105263953B (zh) * | 2014-01-15 | 2020-01-07 | 勃林格殷格翰动物保健美国有限公司 | 猪细小病毒5a、使用方法及疫苗 |
| CN107073089A (zh) * | 2014-05-19 | 2017-08-18 | 瓦洛治疗公司 | 用于癌症疫苗的包被的溶瘤腺病毒 |
| CN111978382A (zh) * | 2020-09-03 | 2020-11-24 | 吉林大学第一医院 | 一种球形孢子丝菌Gp70重组蛋白的制备方法及其应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1032420A4 (en) | 2004-09-15 |
| IL136114A0 (en) | 2001-05-20 |
| KR20010015818A (ko) | 2001-02-26 |
| JP2001526021A (ja) | 2001-12-18 |
| EP1030684A1 (en) | 2000-08-30 |
| EP1030684A4 (en) | 2004-09-15 |
| AU1459899A (en) | 1999-06-07 |
| EP1032420A1 (en) | 2000-09-06 |
| AU2003252902A1 (en) | 2003-11-06 |
| WO1999025379A1 (en) | 1999-05-27 |
| AU763029B2 (en) | 2003-07-10 |
| WO1999025378A9 (en) | 1999-08-12 |
| JP2002507544A (ja) | 2002-03-12 |
| AU1459799A (en) | 1999-06-07 |
| CA2309990A1 (en) | 1999-05-27 |
| BR9815289A (pt) | 2001-12-26 |
| AU737457B2 (en) | 2001-08-23 |
| IL136113A0 (en) | 2001-05-20 |
| CA2310269A1 (en) | 1999-05-27 |
| CN1327388A (zh) | 2001-12-19 |
| WO1999025378A1 (en) | 1999-05-27 |
| BR9815580A (pt) | 2002-01-29 |
| KR20010015817A (ko) | 2001-02-26 |
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