CN1277824C - 哌嗪衍生物 - Google Patents
哌嗪衍生物 Download PDFInfo
- Publication number
- CN1277824C CN1277824C CNB018206115A CN01820611A CN1277824C CN 1277824 C CN1277824 C CN 1277824C CN B018206115 A CNB018206115 A CN B018206115A CN 01820611 A CN01820611 A CN 01820611A CN 1277824 C CN1277824 C CN 1277824C
- Authority
- CN
- China
- Prior art keywords
- piperazine
- carboxylic acid
- ester
- cis
- carboxylate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
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- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Diabetes (AREA)
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- Obesity (AREA)
- Addiction (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0030710.8 | 2000-12-15 | ||
| GBGB0030710.8A GB0030710D0 (en) | 2000-12-15 | 2000-12-15 | Piperazine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1533382A CN1533382A (zh) | 2004-09-29 |
| CN1277824C true CN1277824C (zh) | 2006-10-04 |
Family
ID=9905222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB018206115A Expired - Fee Related CN1277824C (zh) | 2000-12-15 | 2001-12-06 | 哌嗪衍生物 |
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| Country | Link |
|---|---|
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- 2001-12-06 EP EP01990522A patent/EP1343775B1/en not_active Expired - Lifetime
- 2001-12-06 WO PCT/EP2001/014343 patent/WO2002048124A2/en not_active Ceased
- 2001-12-06 BR BR0116201-2A patent/BR0116201A/pt not_active IP Right Cessation
- 2001-12-06 AU AU2962602A patent/AU2962602A/xx active Pending
- 2001-12-06 KR KR1020037008003A patent/KR100623833B1/ko not_active Expired - Fee Related
- 2001-12-06 CN CNB018206115A patent/CN1277824C/zh not_active Expired - Fee Related
- 2001-12-06 JP JP2002549655A patent/JP4047724B2/ja not_active Expired - Fee Related
- 2001-12-06 ES ES01990522T patent/ES2306736T3/es not_active Expired - Lifetime
- 2001-12-06 DE DE60134338T patent/DE60134338D1/de not_active Expired - Lifetime
- 2001-12-06 AT AT01990522T patent/ATE397595T1/de not_active IP Right Cessation
- 2001-12-06 MX MXPA03005270A patent/MXPA03005270A/es unknown
- 2001-12-07 US US10/010,058 patent/US20020143020A1/en not_active Abandoned
- 2001-12-12 AR ARP010105788A patent/AR035517A1/es not_active Application Discontinuation
- 2001-12-12 PA PA20018534801A patent/PA8534801A1/es unknown
- 2001-12-13 PE PE2001001247A patent/PE20020667A1/es not_active Application Discontinuation
- 2001-12-14 UY UY27075A patent/UY27075A1/es not_active Application Discontinuation
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2003
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111646949A (zh) * | 2020-06-12 | 2020-09-11 | 上海馨远医药科技有限公司 | 一种2,6-二甲基哌嗪二盐酸盐的制备方法 |
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| ATE397595T1 (de) | 2008-06-15 |
| EP1343775B1 (en) | 2008-06-04 |
| AR035517A1 (es) | 2004-06-02 |
| CA2430601A1 (en) | 2002-06-20 |
| CN1533382A (zh) | 2004-09-29 |
| UY27075A1 (es) | 2002-07-31 |
| ES2306736T3 (es) | 2008-11-16 |
| PE20020667A1 (es) | 2002-07-27 |
| WO2002048124A2 (en) | 2002-06-20 |
| GB0030710D0 (en) | 2001-01-31 |
| JP4047724B2 (ja) | 2008-02-13 |
| DE60134338D1 (de) | 2008-07-17 |
| KR20030072563A (ko) | 2003-09-15 |
| ZA200304346B (en) | 2004-09-03 |
| EP1343775A2 (en) | 2003-09-17 |
| JP2004519438A (ja) | 2004-07-02 |
| WO2002048124A3 (en) | 2003-06-05 |
| US20020143020A1 (en) | 2002-10-03 |
| US7022707B2 (en) | 2006-04-04 |
| CA2430601C (en) | 2008-05-06 |
| AU2962602A (en) | 2002-06-24 |
| MXPA03005270A (es) | 2003-09-25 |
| BR0116201A (pt) | 2004-03-02 |
| US20040235859A1 (en) | 2004-11-25 |
| KR100623833B1 (ko) | 2006-09-18 |
| PA8534801A1 (es) | 2002-08-26 |
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