CN1276978C - 制备3－[2－{(甲基磺酰基)氧)乙氧基)－4－(三苯基甲氧基)－1－丁醇甲烷磺酸酯的方法 - Google Patents

制备3－[2－{(甲基磺酰基)氧)乙氧基)－4－(三苯基甲氧基)－1－丁醇甲烷磺酸酯的方法 Download PDF

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Publication number
CN1276978C
CN1276978C CNB018207529A CN01820752A CN1276978C CN 1276978 C CN1276978 C CN 1276978C CN B018207529 A CNB018207529 A CN B018207529A CN 01820752 A CN01820752 A CN 01820752A CN 1276978 C CN1276978 C CN 1276978C
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China
Prior art keywords
isomer
dihydropyrane
compound
reaction
racemic mixture
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CNB018207529A
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English (en)
Chinese (zh)
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CN1633504A (zh
Inventor
J－C·卡耶
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PPG Industries Ohio Inc
PPG Industries Inc
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PPG Industries Inc
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Publication of CN1276978C publication Critical patent/CN1276978C/zh
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/001—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by metabolizing one of the enantiomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/26—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of esters of sulfonic acids
    • C07C303/28—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of esters of sulfonic acids by reaction of hydroxy compounds with sulfonic acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/20—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hydrogen atoms and substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D309/22—Radicals substituted by oxygen atoms
    • C07D309/24—Methylol radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P11/00—Preparation of sulfur-containing organic compounds

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CNB018207529A 2000-11-22 2001-10-30 制备3－[2－{(甲基磺酰基)氧)乙氧基)－4－(三苯基甲氧基)－1－丁醇甲烷磺酸酯的方法 Expired - Fee Related CN1276978C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/718,711 US6300106B1 (en) 2000-11-22 2000-11-22 Method of preparing 3-[2-{(Methylsulfonyl)oxy}-ethoxy ]-4-(triphenylmethoxy)-1-butanol, methane sulfonate
US09/718,711 2000-11-22

Publications (2)

Publication Number Publication Date
CN1633504A CN1633504A (zh) 2005-06-29
CN1276978C true CN1276978C (zh) 2006-09-27

Family

ID=24887178

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB018207529A Expired - Fee Related CN1276978C (zh) 2000-11-22 2001-10-30 制备3－[2－{(甲基磺酰基)氧)乙氧基)－4－(三苯基甲氧基)－1－丁醇甲烷磺酸酯的方法

Country Status (11)

Country Link
US (1) US6300106B1 (pt)
EP (1) EP1341927B1 (pt)
JP (2) JP4133328B2 (pt)
CN (1) CN1276978C (pt)
AT (1) ATE335090T1 (pt)
CA (1) CA2429775A1 (pt)
DE (1) DE60121994T2 (pt)
DK (1) DK1341927T3 (pt)
ES (1) ES2267857T3 (pt)
PT (1) PT1341927E (pt)
WO (1) WO2002059342A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2181999A1 (en) 2008-11-03 2010-05-05 Zentiva, A.S. Method of manufacturing ruboxistarin

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2655341B1 (fr) * 1989-12-01 1992-02-21 Rhone Poulenc Sante Derives dihydropyranniques, leurs procedes de preparation et leur utilisation.
DK0776899T3 (da) 1995-11-20 2000-07-10 Lilly Co Eli Mellemprodukter og deres anvendelse til fremstilling af N,N'-forbundne bisindolylmaleimider
NZ323571A (en) * 1995-11-20 1998-12-23 Lilly Co Eli Protein kinase c inhibitor
US5721272A (en) * 1996-11-18 1998-02-24 Eli Lilly And Company Intermediates and their use to prepare N,N'-bridged bisindolylmaleimides

Also Published As

Publication number Publication date
ES2267857T3 (es) 2007-03-16
JP4133328B2 (ja) 2008-08-13
JP2008263985A (ja) 2008-11-06
CA2429775A1 (en) 2002-08-01
ATE335090T1 (de) 2006-08-15
DE60121994D1 (de) 2006-09-14
CN1633504A (zh) 2005-06-29
EP1341927A1 (en) 2003-09-10
WO2002059342A1 (en) 2002-08-01
EP1341927B1 (en) 2006-08-02
US6300106B1 (en) 2001-10-09
PT1341927E (pt) 2006-12-29
DE60121994T2 (de) 2007-03-15
DK1341927T3 (da) 2006-11-13
JP2006506941A (ja) 2006-03-02

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