CN1244565C - 对于制备二芳基甲基哌嗪衍生物的新不对称方法和新不对称二芳基甲胺中间体 - Google Patents
对于制备二芳基甲基哌嗪衍生物的新不对称方法和新不对称二芳基甲胺中间体 Download PDFInfo
- Publication number
- CN1244565C CN1244565C CNB028060326A CN02806032A CN1244565C CN 1244565 C CN1244565 C CN 1244565C CN B028060326 A CNB028060326 A CN B028060326A CN 02806032 A CN02806032 A CN 02806032A CN 1244565 C CN1244565 C CN 1244565C
- Authority
- CN
- China
- Prior art keywords
- compound
- general formula
- definition
- methyl
- obtains
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Quinoline Compounds (AREA)
- Furan Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE01007640 | 2001-03-07 | ||
| SE0100764A SE0100764D0 (sv) | 2001-03-07 | 2001-03-07 | New assymetric process |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2005100879382A Division CN1295217C (zh) | 2001-03-07 | 2002-03-05 | 用于制备二芳基甲基哌嗪衍生物的新不对称二芳基甲胺中间体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1494532A CN1494532A (zh) | 2004-05-05 |
| CN1244565C true CN1244565C (zh) | 2006-03-08 |
Family
ID=20283236
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB028060326A Expired - Fee Related CN1244565C (zh) | 2001-03-07 | 2002-03-05 | 对于制备二芳基甲基哌嗪衍生物的新不对称方法和新不对称二芳基甲胺中间体 |
| CNB2005100879382A Expired - Fee Related CN1295217C (zh) | 2001-03-07 | 2002-03-05 | 用于制备二芳基甲基哌嗪衍生物的新不对称二芳基甲胺中间体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2005100879382A Expired - Fee Related CN1295217C (zh) | 2001-03-07 | 2002-03-05 | 用于制备二芳基甲基哌嗪衍生物的新不对称二芳基甲胺中间体 |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US7045625B2 (enExample) |
| EP (1) | EP1368325B1 (enExample) |
| JP (1) | JP2004522793A (enExample) |
| KR (1) | KR100856996B1 (enExample) |
| CN (2) | CN1244565C (enExample) |
| AT (1) | ATE406354T1 (enExample) |
| BR (1) | BR0207817A (enExample) |
| CA (1) | CA2440104A1 (enExample) |
| DE (1) | DE60228548D1 (enExample) |
| DK (1) | DK1368325T3 (enExample) |
| ES (1) | ES2311050T3 (enExample) |
| IL (1) | IL157460A0 (enExample) |
| MX (1) | MXPA03007889A (enExample) |
| NO (1) | NO325156B1 (enExample) |
| NZ (1) | NZ527656A (enExample) |
| PT (1) | PT1368325E (enExample) |
| SE (1) | SE0100764D0 (enExample) |
| SI (1) | SI1368325T1 (enExample) |
| WO (1) | WO2002070492A1 (enExample) |
| ZA (1) | ZA200306448B (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114560781A (zh) * | 2022-03-01 | 2022-05-31 | 无锡捷化医药科技有限公司 | 一种n,n-二(2-氯乙基)-4-硝基苯基丙氨酸甲酯的制备方法 |
| CN114702457A (zh) * | 2022-03-30 | 2022-07-05 | 青岛科技大学 | 一种二芳基甲胺类化合物的绿色合成方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9202238D0 (en) * | 1992-02-03 | 1992-03-18 | Wellcome Found | Compounds |
| DK0711289T3 (da) * | 1993-07-30 | 2000-11-06 | Delta Pharmaceuticals Inc | Piperazinforbindelser til anvendelse i terapi |
| SE9504661D0 (sv) * | 1995-12-22 | 1995-12-22 | Astra Pharma Inc | New compounds |
| SE9904673D0 (sv) * | 1999-12-20 | 1999-12-20 | Astra Pharma Inc | Novel compounds |
| SE0001209D0 (sv) | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
-
2001
- 2001-03-07 SE SE0100764A patent/SE0100764D0/xx unknown
-
2002
- 2002-03-05 US US10/468,989 patent/US7045625B2/en not_active Expired - Fee Related
- 2002-03-05 AT AT02701852T patent/ATE406354T1/de not_active IP Right Cessation
- 2002-03-05 PT PT02701852T patent/PT1368325E/pt unknown
- 2002-03-05 EP EP02701852A patent/EP1368325B1/en not_active Expired - Lifetime
- 2002-03-05 SI SI200230739T patent/SI1368325T1/sl unknown
- 2002-03-05 NZ NZ527656A patent/NZ527656A/en unknown
- 2002-03-05 IL IL15746002A patent/IL157460A0/xx unknown
- 2002-03-05 JP JP2002569812A patent/JP2004522793A/ja active Pending
- 2002-03-05 KR KR1020037011675A patent/KR100856996B1/ko not_active Expired - Fee Related
- 2002-03-05 ES ES02701852T patent/ES2311050T3/es not_active Expired - Lifetime
- 2002-03-05 DE DE60228548T patent/DE60228548D1/de not_active Expired - Fee Related
- 2002-03-05 CA CA002440104A patent/CA2440104A1/en not_active Abandoned
- 2002-03-05 CN CNB028060326A patent/CN1244565C/zh not_active Expired - Fee Related
- 2002-03-05 CN CNB2005100879382A patent/CN1295217C/zh not_active Expired - Fee Related
- 2002-03-05 DK DK02701852T patent/DK1368325T3/da active
- 2002-03-05 BR BR0207817-1A patent/BR0207817A/pt not_active IP Right Cessation
- 2002-03-05 MX MXPA03007889A patent/MXPA03007889A/es active IP Right Grant
- 2002-03-05 WO PCT/SE2002/000376 patent/WO2002070492A1/en not_active Ceased
-
2003
- 2003-08-19 ZA ZA200306448A patent/ZA200306448B/en unknown
- 2003-09-05 NO NO20033944A patent/NO325156B1/no not_active IP Right Cessation
-
2005
- 2005-11-22 US US11/285,672 patent/US7423154B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| KR100856996B1 (ko) | 2008-09-04 |
| DK1368325T3 (da) | 2008-11-24 |
| ATE406354T1 (de) | 2008-09-15 |
| EP1368325B1 (en) | 2008-08-27 |
| CN1721407A (zh) | 2006-01-18 |
| BR0207817A (pt) | 2004-03-09 |
| DE60228548D1 (de) | 2008-10-09 |
| KR20030080075A (ko) | 2003-10-10 |
| NO325156B1 (no) | 2008-02-11 |
| CN1494532A (zh) | 2004-05-05 |
| NO20033944L (no) | 2003-10-31 |
| NO20033944D0 (no) | 2003-09-05 |
| SI1368325T1 (sl) | 2008-12-31 |
| CN1295217C (zh) | 2007-01-17 |
| ZA200306448B (en) | 2004-09-08 |
| CA2440104A1 (en) | 2002-09-12 |
| MXPA03007889A (es) | 2003-12-04 |
| US7045625B2 (en) | 2006-05-16 |
| WO2002070492A1 (en) | 2002-09-12 |
| IL157460A0 (en) | 2004-03-28 |
| NZ527656A (en) | 2005-04-29 |
| US20040077861A1 (en) | 2004-04-22 |
| EP1368325A1 (en) | 2003-12-10 |
| US20060074238A1 (en) | 2006-04-06 |
| US7423154B2 (en) | 2008-09-09 |
| HK1059436A1 (en) | 2004-07-02 |
| JP2004522793A (ja) | 2004-07-29 |
| SE0100764D0 (sv) | 2001-03-07 |
| ES2311050T3 (es) | 2009-02-01 |
| PT1368325E (pt) | 2008-10-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20060308 Termination date: 20100305 |