ES2311050T3 - Nuevo procedimiento asimetrico para la preparacion de derivados de diarilmetilpiperazinas y nuevas diarilmetilaminas asimetricas como intermedios. - Google Patents

Nuevo procedimiento asimetrico para la preparacion de derivados de diarilmetilpiperazinas y nuevas diarilmetilaminas asimetricas como intermedios. Download PDF

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Publication number
ES2311050T3
ES2311050T3 ES02701852T ES02701852T ES2311050T3 ES 2311050 T3 ES2311050 T3 ES 2311050T3 ES 02701852 T ES02701852 T ES 02701852T ES 02701852 T ES02701852 T ES 02701852T ES 2311050 T3 ES2311050 T3 ES 2311050T3
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ES
Spain
Prior art keywords
baselineskip
general formula
compound
quad
give
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES02701852T
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English (en)
Spanish (es)
Inventor
William Astrazeneca R & D Montreal Brown
Niklas AstraZeneca R & D Montreal PLOBECK
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
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AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Application granted granted Critical
Publication of ES2311050T3 publication Critical patent/ES2311050T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Quinoline Compounds (AREA)
  • Furan Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ES02701852T 2001-03-07 2002-03-05 Nuevo procedimiento asimetrico para la preparacion de derivados de diarilmetilpiperazinas y nuevas diarilmetilaminas asimetricas como intermedios. Expired - Lifetime ES2311050T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0100764A SE0100764D0 (sv) 2001-03-07 2001-03-07 New assymetric process
SE0100764 2001-03-07

Publications (1)

Publication Number Publication Date
ES2311050T3 true ES2311050T3 (es) 2009-02-01

Family

ID=20283236

Family Applications (1)

Application Number Title Priority Date Filing Date
ES02701852T Expired - Lifetime ES2311050T3 (es) 2001-03-07 2002-03-05 Nuevo procedimiento asimetrico para la preparacion de derivados de diarilmetilpiperazinas y nuevas diarilmetilaminas asimetricas como intermedios.

Country Status (20)

Country Link
US (2) US7045625B2 (enExample)
EP (1) EP1368325B1 (enExample)
JP (1) JP2004522793A (enExample)
KR (1) KR100856996B1 (enExample)
CN (2) CN1244565C (enExample)
AT (1) ATE406354T1 (enExample)
BR (1) BR0207817A (enExample)
CA (1) CA2440104A1 (enExample)
DE (1) DE60228548D1 (enExample)
DK (1) DK1368325T3 (enExample)
ES (1) ES2311050T3 (enExample)
IL (1) IL157460A0 (enExample)
MX (1) MXPA03007889A (enExample)
NO (1) NO325156B1 (enExample)
NZ (1) NZ527656A (enExample)
PT (1) PT1368325E (enExample)
SE (1) SE0100764D0 (enExample)
SI (1) SI1368325T1 (enExample)
WO (1) WO2002070492A1 (enExample)
ZA (1) ZA200306448B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114560781A (zh) * 2022-03-01 2022-05-31 无锡捷化医药科技有限公司 一种n,n-二(2-氯乙基)-4-硝基苯基丙氨酸甲酯的制备方法
CN114702457A (zh) * 2022-03-30 2022-07-05 青岛科技大学 一种二芳基甲胺类化合物的绿色合成方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9202238D0 (en) * 1992-02-03 1992-03-18 Wellcome Found Compounds
DK0711289T3 (da) * 1993-07-30 2000-11-06 Delta Pharmaceuticals Inc Piperazinforbindelser til anvendelse i terapi
SE9504661D0 (sv) * 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
SE9904673D0 (sv) * 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE0001209D0 (sv) 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds

Also Published As

Publication number Publication date
KR100856996B1 (ko) 2008-09-04
DK1368325T3 (da) 2008-11-24
ATE406354T1 (de) 2008-09-15
EP1368325B1 (en) 2008-08-27
CN1721407A (zh) 2006-01-18
BR0207817A (pt) 2004-03-09
DE60228548D1 (de) 2008-10-09
KR20030080075A (ko) 2003-10-10
NO325156B1 (no) 2008-02-11
CN1494532A (zh) 2004-05-05
NO20033944L (no) 2003-10-31
NO20033944D0 (no) 2003-09-05
SI1368325T1 (sl) 2008-12-31
CN1295217C (zh) 2007-01-17
ZA200306448B (en) 2004-09-08
CA2440104A1 (en) 2002-09-12
MXPA03007889A (es) 2003-12-04
US7045625B2 (en) 2006-05-16
WO2002070492A1 (en) 2002-09-12
IL157460A0 (en) 2004-03-28
CN1244565C (zh) 2006-03-08
NZ527656A (en) 2005-04-29
US20040077861A1 (en) 2004-04-22
EP1368325A1 (en) 2003-12-10
US20060074238A1 (en) 2006-04-06
US7423154B2 (en) 2008-09-09
HK1059436A1 (en) 2004-07-02
JP2004522793A (ja) 2004-07-29
SE0100764D0 (sv) 2001-03-07
PT1368325E (pt) 2008-10-27

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