CN1218692C - 新型薄膜包衣 - Google Patents

新型薄膜包衣 Download PDF

Info

Publication number
CN1218692C
CN1218692C CNB028040813A CN02804081A CN1218692C CN 1218692 C CN1218692 C CN 1218692C CN B028040813 A CNB028040813 A CN B028040813A CN 02804081 A CN02804081 A CN 02804081A CN 1218692 C CN1218692 C CN 1218692C
Authority
CN
China
Prior art keywords
film coating
surfactant
preparation
acrylic polymer
sodium stearyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB028040813A
Other languages
English (en)
Chinese (zh)
Other versions
CN1487828A (zh
Inventor
A·赫尔泽尔
J·－E·勒夫罗斯
S·尚茨
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of CN1487828A publication Critical patent/CN1487828A/zh
Application granted granted Critical
Publication of CN1218692C publication Critical patent/CN1218692C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Paints Or Removers (AREA)
  • Surface Treatment Of Glass Fibres Or Filaments (AREA)
  • Laminated Bodies (AREA)
CNB028040813A 2001-01-24 2002-01-22 新型薄膜包衣 Expired - Fee Related CN1218692C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0100200A SE0100200D0 (sv) 2001-01-24 2001-01-24 New film coating
SE01002005 2001-01-24

Publications (2)

Publication Number Publication Date
CN1487828A CN1487828A (zh) 2004-04-07
CN1218692C true CN1218692C (zh) 2005-09-14

Family

ID=20282714

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB028040813A Expired - Fee Related CN1218692C (zh) 2001-01-24 2002-01-22 新型薄膜包衣

Country Status (21)

Country Link
US (1) US7959947B2 (enExample)
EP (1) EP1355635B1 (enExample)
JP (1) JP4303471B2 (enExample)
KR (1) KR100874582B1 (enExample)
CN (1) CN1218692C (enExample)
AT (1) ATE285229T1 (enExample)
AU (1) AU2002225573B2 (enExample)
BR (1) BR0206515A (enExample)
CA (1) CA2433530A1 (enExample)
DE (2) DE60202351T2 (enExample)
DK (1) DK1355635T3 (enExample)
ES (1) ES2233804T3 (enExample)
IL (2) IL156623A0 (enExample)
MX (1) MXPA03006419A (enExample)
NO (1) NO20033305L (enExample)
NZ (1) NZ526792A (enExample)
PT (1) PT1355635E (enExample)
SE (1) SE0100200D0 (enExample)
SI (1) SI1355635T1 (enExample)
WO (1) WO2002058677A1 (enExample)
ZA (1) ZA200305457B (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0100200D0 (sv) 2001-01-24 2001-01-24 Astrazeneca Ab New film coating
EP1355633B1 (en) * 2001-12-19 2005-01-19 AstraZeneca AB NEW FILM COATING containing an ethyl acrylate/methyl methacrylate copolymer and polyvinyl acetate
US8323692B2 (en) 2002-02-21 2012-12-04 Valeant International Bermuda Controlled release dosage forms
ES2377729T3 (es) * 2002-02-21 2012-03-30 Valeant International (Barbados) Srl Formulaciones de liberación modificada de al menos una forma de tramadol
SE0201110D0 (sv) * 2002-04-12 2002-04-12 Astrazeneca Ab New film coating
SE0202353D0 (sv) * 2002-08-01 2002-08-01 Astrazeneca Ab New film coating
AU2003282375A1 (en) * 2003-02-05 2004-08-30 Ipca Laboratories Limited Pharmaceutical compositions and process of production thereof
RU2372893C2 (ru) * 2003-10-31 2009-11-20 Хексал Аг Содержащий фармацевтический агент состав с покрытием
GB0403098D0 (en) 2004-02-12 2004-03-17 Euro Celtique Sa Extrusion
TWI350762B (en) 2004-02-12 2011-10-21 Euro Celtique Sa Particulates
DE14172396T1 (de) 2004-10-08 2015-01-08 Forward Pharma A/S Gesteuerte Freisetzung von pharmazeutischen Zusammensetzungen mit Fumarinsäureester
CN102369000A (zh) * 2009-01-09 2012-03-07 前进制药公司 包含一种或多种富马酸酯的药用组合物
CN109044985A (zh) 2009-01-09 2018-12-21 前进制药知识产权有限公司 包含溶蚀骨架中的一种或多种富马酸酯的药物制剂
US20100303920A1 (en) * 2009-05-27 2010-12-02 Johan Hjartstam Aqueous Film Coating Composition / 841
US20110229564A1 (en) * 2010-03-22 2011-09-22 Amneal Pharmaceuticals, L.L.C. Pharmaceutical Compositions Of Carvedilol Salts And Process For Preparation Thereof
EP2844296B1 (en) * 2012-05-02 2019-03-13 Capsugel Belgium NV Aqueous dispersions of hydroxypropyl methylcellulose acetate succinate (hpmcas)
MX2015010449A (es) 2013-02-13 2015-10-30 Evonik Roehm Gmbh Composicion farmaceutica multiparticulada que comprende una multitud de dos clases de granulos.
EP3065720A1 (en) 2013-11-04 2016-09-14 Capsugel Belgium NV Methods and systems for improved bioavailability of active pharmaceutical ingredients including esomeprazole
CN105085778B (zh) * 2014-04-22 2018-11-16 广东华润涂料有限公司 用于缓释功能成分的涂料组合物用水性胶乳、其制备方法以及应用
RS62275B1 (sr) * 2015-03-03 2021-09-30 Saniona As Kombinovana formulacija tesofensina i metoprolola
MA45553A (fr) * 2016-06-30 2019-05-08 Beckman Coulter Inc Substrats chimioluminescents
WO2019183470A2 (en) 2018-03-22 2019-09-26 Incarda Therapeutics, Inc. A novel method to slow ventricular rate

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB878234A (en) 1958-12-18 1961-09-27 Roehm & Haas Gmbh Pharmaceutical coating compositions
DE1228757B (de) * 1962-06-28 1966-11-17 Haessle Ab Verfahren zur Herstellung eines in Wasser und Magensaft rasch zerfallenden UEberzuges auf festen Arzneiformen
US3341338A (en) * 1965-05-28 1967-09-12 Union Carbide Corp Polysiloxane polish formulations
DE2031871C3 (de) * 1970-06-27 1974-06-27 Roehm Gmbh, 6100 Darmstadt Überzugsmasse für Arzneiformen
US4330338A (en) * 1978-10-02 1982-05-18 Purdue Research Foundation Pharmaceutical coating composition, and preparation and dosages so coated
US4353887A (en) * 1979-08-16 1982-10-12 Ciba-Geigy Corporation Divisible tablet having controlled and delayed release of the active substance
US4916171A (en) * 1984-07-25 1990-04-10 Rohm And Haas Company Polymers comprising alkali-insoluble core/alkali-soluble shell and copositions thereof
SE8404467D0 (sv) 1984-09-06 1984-09-06 Ferrosan Ab Controlled-release medical preparations
CH666405A5 (de) * 1985-06-24 1988-07-29 Ciba Geigy Ag Feste, haltbare darreichungsformen mit elastischem filmueberzug.
SE455836B (sv) * 1985-10-11 1988-08-15 Haessle Ab Beredning med kontrollerad frisettning innehallande ett salt av metoprolol samt metod for framstellning av denna beredning
US5246714A (en) * 1985-10-11 1993-09-21 Aktiebolaget Hassle Drug preparation
SE450087B (sv) * 1985-10-11 1987-06-09 Haessle Ab Korn med kontrollerad frisettning av farmaceutiskt aktiva emnen som anbringats teckande pa ett kompakt olosligt kernmaterial
US4975283A (en) * 1985-12-12 1990-12-04 Bristol-Myers Squibb Company Stabilized enteric coated aspirin granules and process for preparation
US4800087A (en) * 1986-11-24 1989-01-24 Mehta Atul M Taste-masked pharmaceutical compositions
US4871546A (en) * 1987-06-29 1989-10-03 Sandoz Pharm. Corp. Gastrointestinal protective coating formulations
EP0313845A1 (en) 1987-09-29 1989-05-03 Warner-Lambert Company Stabilization of enteric coated dosage form
FR2655266B1 (fr) 1989-12-05 1992-04-03 Smith Kline French Lab Compositions pharmaceutiques a base de cimetidine.
JP2558396B2 (ja) 1990-06-28 1996-11-27 田辺製薬株式会社 放出制御型製剤
GB9200607D0 (en) * 1992-01-13 1992-03-11 Ethical Pharma Ltd Pharmaceutical compositions containing nifedipine and process for the preparation thereof
US5656296A (en) * 1992-04-29 1997-08-12 Warner-Lambert Company Dual control sustained release drug delivery systems and methods for preparing same
US5376384A (en) * 1992-12-23 1994-12-27 Kinaform Technology, Inc. Delayed, sustained-release pharmaceutical preparation
PT621032E (pt) * 1993-04-23 2001-01-31 Novartis Ag Dispositivo de distribuicao de libertacao controlada de farmaco
US5484597A (en) * 1993-07-30 1996-01-16 Chesebrough-Pond's Usa Co. Clear hydroalcholic cosmetic microemulsions
FR2725623A1 (fr) 1994-10-18 1996-04-19 Flamel Tech Sa Microcapsules medicamenteuses et/ou nutritionnelles pour administration per os
DE4444051A1 (de) * 1994-12-10 1996-06-13 Rhone Poulenc Rorer Gmbh Pharmazeutische, oral anwendbare Zubereitung
US5948438A (en) * 1995-01-09 1999-09-07 Edward Mendell Co., Inc. Pharmaceutical formulations having improved disintegration and/or absorptivity
US5871776A (en) * 1995-01-31 1999-02-16 Mehta; Atul M. Controlled-release nifedipine
DE69713948D1 (de) * 1996-04-23 2002-08-22 Janssen Pharmaceutica Nv Rasch-freisetzende pH-unabhängige feste Dosisformen enthaltend Cisaprid
US6046177A (en) * 1997-05-05 2000-04-04 Cydex, Inc. Sulfoalkyl ether cyclodextrin based controlled release solid pharmaceutical formulations
US6627223B2 (en) * 2000-02-11 2003-09-30 Eurand Pharmaceuticals Ltd. Timed pulsatile drug delivery systems
SE0100200D0 (sv) 2001-01-24 2001-01-24 Astrazeneca Ab New film coating
EP1355633B1 (en) * 2001-12-19 2005-01-19 AstraZeneca AB NEW FILM COATING containing an ethyl acrylate/methyl methacrylate copolymer and polyvinyl acetate
SE0201110D0 (sv) * 2002-04-12 2002-04-12 Astrazeneca Ab New film coating
SE0202353D0 (sv) * 2002-08-01 2002-08-01 Astrazeneca Ab New film coating

Also Published As

Publication number Publication date
NZ526792A (en) 2004-12-24
SE0100200D0 (sv) 2001-01-24
WO2002058677A1 (en) 2002-08-01
JP4303471B2 (ja) 2009-07-29
ES2233804T3 (es) 2005-06-16
SI1355635T1 (en) 2005-06-30
MXPA03006419A (es) 2003-10-15
CA2433530A1 (en) 2002-08-01
US7959947B2 (en) 2011-06-14
AU2002225573B2 (en) 2006-09-07
DE20220901U1 (de) 2004-06-17
EP1355635A1 (en) 2003-10-29
ATE285229T1 (de) 2005-01-15
KR20030070122A (ko) 2003-08-27
HK1063432A1 (en) 2004-12-31
NO20033305D0 (no) 2003-07-22
DE60202351T2 (de) 2005-12-01
US20040058001A1 (en) 2004-03-25
ZA200305457B (en) 2004-10-15
IL156623A (en) 2007-12-03
BR0206515A (pt) 2004-02-17
IL156623A0 (en) 2004-01-04
DK1355635T3 (da) 2005-03-29
EP1355635B1 (en) 2004-12-22
NO20033305L (no) 2003-07-22
KR100874582B1 (ko) 2008-12-16
JP2004522741A (ja) 2004-07-29
PT1355635E (pt) 2005-04-29
DE60202351D1 (de) 2005-01-27
CN1487828A (zh) 2004-04-07

Similar Documents

Publication Publication Date Title
CN1218692C (zh) 新型薄膜包衣
CN1278678C (zh) 具有高生物利用率的非诺贝特药物组合物及其制备方法
CN1142212C (zh) 用于口服或皮肤用药物剂型的涂层和粘结剂
CN1201732C (zh) 缓释的口服药物形式
CN1298317C (zh) 坦洛新片剂
CN1292742C (zh) 阿片类药物延缓控释制剂
CN1025283C (zh) 生产控制释放产品时用的小珠的制备方法
CN1419445A (zh) 用于提高了储存稳定性的药物制剂的包衣及粘合剂
CN1625390A (zh) 多级口服药物控释系统
CN1503663A (zh) 新的膜衣
CN1697649A (zh) 药物剂型及其制备方法
CN1308520A (zh) 具有单一核心的控释口服片剂
AU2002225573A1 (en) New film coating
US20130034604A1 (en) Extended release formulations of desvenlafaxine base
CN1942173A (zh) 稳定性提高的固体制剂及其制造方法
CN1929839A (zh) 托哌酮的口服控释药物组合物
CN1092957C (zh) β－苯基苯基·乙基酮衍生物的缓释微粒药片
US9668998B2 (en) Solid molecular dispersion of fesoterodine hydrogen fumarate and polymeric binder
CN1549705A (zh) 新的缓释口服剂型
HK1063432B (en) New film coating
CN1822818A (zh) 含有共沉淀剂形式的活性剂的颗粒
CN1732925A (zh) 一种洛伐他汀缓释微丸及其制备方法
CN1946376A (zh) 包衣片剂组合物及其制法
HK1098057A (en) Pharmaceutical agent-containing formulation comprising a coating
HK1054867A (en) Sustained-release formulations for treating cns-mediated disorders

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1063432

Country of ref document: HK

C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20050914

Termination date: 20170122

CF01 Termination of patent right due to non-payment of annual fee