CN1207302C - 治疗突变引起的疾病的方法和化合物 - Google Patents

治疗突变引起的疾病的方法和化合物 Download PDF

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CN1207302C
CN1207302C CNB971959498A CN97195949A CN1207302C CN 1207302 C CN1207302 C CN 1207302C CN B971959498 A CNB971959498 A CN B971959498A CN 97195949 A CN97195949 A CN 97195949A CN 1207302 C CN1207302 C CN 1207302C
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dna
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CN1223660A (zh
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E·B·克米埃克
A·科勒－斯特劳斯
K·尤恩
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Thomas Jefferson University
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
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    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
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    • C07—ORGANIC CHEMISTRY
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/32—Chemical structure of the sugar
    • C12N2310/321—2'-O-R Modification
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/50—Physical structure
    • C12N2310/53—Physical structure partially self-complementary or closed

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CNB971959498A 1996-05-01 1997-05-01 治疗突变引起的疾病的方法和化合物 Expired - Fee Related CN1207302C (zh)

Applications Claiming Priority (2)

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US08/640,517 US5760012A (en) 1996-05-01 1996-05-01 Methods and compounds for curing diseases caused by mutations
US08/640,517 1996-05-01

Publications (2)

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CN1223660A CN1223660A (zh) 1999-07-21
CN1207302C true CN1207302C (zh) 2005-06-22

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US (1) US5760012A (enExample)
EP (1) EP0906328A4 (enExample)
JP (1) JP2000509282A (enExample)
KR (1) KR20000064969A (enExample)
CN (1) CN1207302C (enExample)
AU (1) AU708658B2 (enExample)
CA (1) CA2252762A1 (enExample)
NZ (1) NZ332297A (enExample)
WO (1) WO1997041141A1 (enExample)

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