CN1201003C - 脂肪细胞特异性蛋白质同系物 - Google Patents

脂肪细胞特异性蛋白质同系物 Download PDF

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Publication number
CN1201003C
CN1201003C CNB988089114A CN98808911A CN1201003C CN 1201003 C CN1201003 C CN 1201003C CN B988089114 A CNB988089114 A CN B988089114A CN 98808911 A CN98808911 A CN 98808911A CN 1201003 C CN1201003 C CN 1201003C
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China
Prior art keywords
polypeptide
seq
sequence
gly
residue
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Expired - Fee Related
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CNB988089114A
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English (en)
Chinese (zh)
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CN1272883A (zh
Inventor
P·O·施帕德
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Zymogenetics Inc
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Zymogenetics Inc
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Publication of CN1272883A publication Critical patent/CN1272883A/zh
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Publication of CN1201003C publication Critical patent/CN1201003C/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CNB988089114A 1997-07-18 1998-07-17 脂肪细胞特异性蛋白质同系物 Expired - Fee Related CN1201003C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5315497P 1997-07-18 1997-07-18
US60/053,154 1997-07-18

Publications (2)

Publication Number Publication Date
CN1272883A CN1272883A (zh) 2000-11-08
CN1201003C true CN1201003C (zh) 2005-05-11

Family

ID=21982287

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB988089114A Expired - Fee Related CN1201003C (zh) 1997-07-18 1998-07-17 脂肪细胞特异性蛋白质同系物

Country Status (18)

Country Link
US (2) US6265544B1 (https=)
EP (1) EP1002075B1 (https=)
JP (1) JP3762220B2 (https=)
KR (1) KR100385868B1 (https=)
CN (1) CN1201003C (https=)
AT (1) ATE327328T1 (https=)
AU (1) AU743745B2 (https=)
BR (1) BR9810917A (https=)
CA (1) CA2296530A1 (https=)
DE (1) DE69834643T2 (https=)
DK (1) DK1002075T3 (https=)
ES (1) ES2264207T3 (https=)
HU (1) HUP0003762A3 (https=)
IL (1) IL134011A0 (https=)
NO (1) NO20000215L (https=)
PL (1) PL338139A1 (https=)
RU (1) RU2218402C2 (https=)
WO (1) WO1999004000A1 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020137890A1 (en) * 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
HUP0003762A3 (en) * 1997-07-18 2005-11-28 Zymogenetics Inc Adipocyte-specific protein homologs
US6566499B1 (en) * 1997-07-18 2003-05-20 Zymogenetics, Inc. Adipocyte-specific protein homologs
FR2767135B1 (fr) 1997-08-06 2002-07-12 Genset Sa Recepteur complexe lsr, activite, clonage, et application au diagnostic, a la prevention et/ou au traitement de d'obesite et des risques ou complications associes
US20030129691A1 (en) * 1998-02-09 2003-07-10 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US7300774B1 (en) 1999-12-09 2007-11-27 The Regents Of The University Of California Multimeric fusion proteins of the TNF superfamily ligands
DE60004015T2 (de) * 1999-02-19 2004-04-15 Zymogenetics, Inc., Seattle Inhibitoren für homöostase und immunfunktion
US6544946B1 (en) * 1999-02-19 2003-04-08 Zymogenetics, Inc. Inhibitors for use in hemostasis and immune function
US20040014650A1 (en) * 2002-07-17 2004-01-22 Sheppard Paul D Methods for enhancing wound repair
AU5037100A (en) * 1999-05-27 2000-12-18 Zymogenetics Inc. Adipocyte complement related protein homolog zacrp6
JP2003501027A (ja) * 1999-05-27 2003-01-14 ザイモジェネティクス，インコーポレイティド 脂肪細胞補体関連タンパク質同族体ｚａｃｒｐ５
US20050042719A1 (en) * 1999-05-27 2005-02-24 Zymogenetics, Inc. Adipocyte complement related protein homolog zacrp5
DE60043367D1 (de) * 1999-06-15 2009-12-31 Genentech Inc Sekretierte und Transmembran-Polypeptide sowie Nukleinsäuren zu deren Kodierung
MXPA01013444A (es) * 1999-07-01 2002-07-22 Zymogenetics Inc Proteina secretada zacrp4.
DE19963859A1 (de) * 1999-12-30 2001-07-12 Apotech Res & Dev Ltd Bi- oder Oligomer eines Di-, Tri-, Quattro- oder Pentamers von rekombinanten Fusionsproteinen
WO2002070704A2 (en) * 2000-11-29 2002-09-12 Zymogenetics, Inc. Adipocyte complement related protein zacrp11
EP1421190A2 (en) 2001-01-16 2004-05-26 Genset Metabolic gene polynucleotides and polypeptides and uses thereof
CA2433841A1 (en) 2001-01-16 2002-08-29 Mary Ruth Erickson Gmg-3, gmg-4, and gmg-6 polynucleotides and polypeptides and uses thereof
US20030220253A1 (en) * 2002-03-08 2003-11-27 Lasser Gerald W. Inhibitors for use in hemostasis
JP2008507591A (ja) * 2004-05-21 2008-03-13 ゼンコー・インコーポレイテッド 免疫原性が改変されたＣ１ｑファミリーメンバータンパク質

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0679716A4 (en) * 1993-11-12 1999-06-09 Kenichi Matsubara GENE SIGNATURE.
US5869330A (en) * 1995-06-05 1999-02-09 Whitehead Institute For Biomedical Research DNA encoding a novel serum protein produced exclusively in adipocytes
HUP0003762A3 (en) * 1997-07-18 2005-11-28 Zymogenetics Inc Adipocyte-specific protein homologs
NZ527900A (en) * 1997-12-03 2005-02-25 Genentech Inc PRO361 polypeptides and nucleic acids with homology to mucin and chitinase

Also Published As

Publication number Publication date
RU2218402C2 (ru) 2003-12-10
JP3762220B2 (ja) 2006-04-05
NO20000215D0 (no) 2000-01-17
NO20000215L (no) 2000-03-17
HUP0003762A2 (hu) 2001-08-28
US20020156243A1 (en) 2002-10-24
HUP0003762A3 (en) 2005-11-28
DK1002075T3 (da) 2006-09-18
CA2296530A1 (en) 1999-01-28
WO1999004000A1 (en) 1999-01-28
AU8411398A (en) 1999-02-10
ATE327328T1 (de) 2006-06-15
EP1002075A1 (en) 2000-05-24
DE69834643T2 (de) 2007-05-10
ES2264207T3 (es) 2006-12-16
PL338139A1 (en) 2000-09-25
US6518403B2 (en) 2003-02-11
KR20010021973A (ko) 2001-03-15
AU743745B2 (en) 2002-02-07
BR9810917A (pt) 2000-08-15
KR100385868B1 (ko) 2003-06-02
DE69834643D1 (de) 2006-06-29
IL134011A0 (en) 2001-04-30
JP2001510045A (ja) 2001-07-31
CN1272883A (zh) 2000-11-08
US6265544B1 (en) 2001-07-24
EP1002075B1 (en) 2006-05-24

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