BR9810917A - Polipeptìdeo isolado, proteìna de fusão, vetor de expressão, célula cultivada, processo para produzir um polipeptìdeo, composição farmacêutica, anticorpo, proteìna de ligação, polinucleotìdeo isolado, e, sonda de oligonucleotìdeo ou iniciador - Google Patents
Polipeptìdeo isolado, proteìna de fusão, vetor de expressão, célula cultivada, processo para produzir um polipeptìdeo, composição farmacêutica, anticorpo, proteìna de ligação, polinucleotìdeo isolado, e, sonda de oligonucleotìdeo ou iniciadorInfo
- Publication number
- BR9810917A BR9810917A BR9810917-0A BR9810917A BR9810917A BR 9810917 A BR9810917 A BR 9810917A BR 9810917 A BR9810917 A BR 9810917A BR 9810917 A BR9810917 A BR 9810917A
- Authority
- BR
- Brazil
- Prior art keywords
- polypeptide
- isolated
- antibody
- pharmaceutical composition
- produce
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 7
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 7
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 7
- 108091033319 polynucleotide Proteins 0.000 title abstract 4
- 102000040430 polynucleotide Human genes 0.000 title abstract 4
- 239000002157 polynucleotide Substances 0.000 title abstract 4
- 239000013604 expression vector Substances 0.000 title abstract 2
- 108020001507 fusion proteins Proteins 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 102000014914 Carrier Proteins Human genes 0.000 title 1
- 108020005187 Oligonucleotide Probes Proteins 0.000 title 1
- -1 antibody Proteins 0.000 title 1
- 108091008324 binding proteins Proteins 0.000 title 1
- 210000004748 cultured cell Anatomy 0.000 title 1
- 102000037865 fusion proteins Human genes 0.000 title 1
- 239000002751 oligonucleotide probe Substances 0.000 title 1
- 239000013615 primer Substances 0.000 title 1
- 239000002987 primer (paints) Substances 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 238000006471 dimerization reaction Methods 0.000 abstract 1
- 238000006384 oligomerization reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5315497P | 1997-07-18 | 1997-07-18 | |
| PCT/US1998/014864 WO1999004000A1 (en) | 1997-07-18 | 1998-07-17 | Adipocyte-specific protein homologs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9810917A true BR9810917A (pt) | 2000-08-15 |
Family
ID=21982287
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9810917-0A BR9810917A (pt) | 1997-07-18 | 1998-07-17 | Polipeptìdeo isolado, proteìna de fusão, vetor de expressão, célula cultivada, processo para produzir um polipeptìdeo, composição farmacêutica, anticorpo, proteìna de ligação, polinucleotìdeo isolado, e, sonda de oligonucleotìdeo ou iniciador |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US6265544B1 (https=) |
| EP (1) | EP1002075B1 (https=) |
| JP (1) | JP3762220B2 (https=) |
| KR (1) | KR100385868B1 (https=) |
| CN (1) | CN1201003C (https=) |
| AT (1) | ATE327328T1 (https=) |
| AU (1) | AU743745B2 (https=) |
| BR (1) | BR9810917A (https=) |
| CA (1) | CA2296530A1 (https=) |
| DE (1) | DE69834643T2 (https=) |
| DK (1) | DK1002075T3 (https=) |
| ES (1) | ES2264207T3 (https=) |
| HU (1) | HUP0003762A3 (https=) |
| IL (1) | IL134011A0 (https=) |
| NO (1) | NO20000215L (https=) |
| PL (1) | PL338139A1 (https=) |
| RU (1) | RU2218402C2 (https=) |
| WO (1) | WO1999004000A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020137890A1 (en) * | 1997-03-31 | 2002-09-26 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| HUP0003762A3 (en) * | 1997-07-18 | 2005-11-28 | Zymogenetics Inc | Adipocyte-specific protein homologs |
| US6566499B1 (en) * | 1997-07-18 | 2003-05-20 | Zymogenetics, Inc. | Adipocyte-specific protein homologs |
| FR2767135B1 (fr) | 1997-08-06 | 2002-07-12 | Genset Sa | Recepteur complexe lsr, activite, clonage, et application au diagnostic, a la prevention et/ou au traitement de d'obesite et des risques ou complications associes |
| US20030129691A1 (en) * | 1998-02-09 | 2003-07-10 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US7300774B1 (en) | 1999-12-09 | 2007-11-27 | The Regents Of The University Of California | Multimeric fusion proteins of the TNF superfamily ligands |
| DE60004015T2 (de) * | 1999-02-19 | 2004-04-15 | Zymogenetics, Inc., Seattle | Inhibitoren für homöostase und immunfunktion |
| US6544946B1 (en) * | 1999-02-19 | 2003-04-08 | Zymogenetics, Inc. | Inhibitors for use in hemostasis and immune function |
| US20040014650A1 (en) * | 2002-07-17 | 2004-01-22 | Sheppard Paul D | Methods for enhancing wound repair |
| AU5037100A (en) * | 1999-05-27 | 2000-12-18 | Zymogenetics Inc. | Adipocyte complement related protein homolog zacrp6 |
| JP2003501027A (ja) * | 1999-05-27 | 2003-01-14 | ザイモジェネティクス，インコーポレイティド | 脂肪細胞補体関連タンパク質同族体ｚａｃｒｐ５ |
| US20050042719A1 (en) * | 1999-05-27 | 2005-02-24 | Zymogenetics, Inc. | Adipocyte complement related protein homolog zacrp5 |
| DE60043367D1 (de) * | 1999-06-15 | 2009-12-31 | Genentech Inc | Sekretierte und Transmembran-Polypeptide sowie Nukleinsäuren zu deren Kodierung |
| MXPA01013444A (es) * | 1999-07-01 | 2002-07-22 | Zymogenetics Inc | Proteina secretada zacrp4. |
| DE19963859A1 (de) * | 1999-12-30 | 2001-07-12 | Apotech Res & Dev Ltd | Bi- oder Oligomer eines Di-, Tri-, Quattro- oder Pentamers von rekombinanten Fusionsproteinen |
| WO2002070704A2 (en) * | 2000-11-29 | 2002-09-12 | Zymogenetics, Inc. | Adipocyte complement related protein zacrp11 |
| EP1421190A2 (en) | 2001-01-16 | 2004-05-26 | Genset | Metabolic gene polynucleotides and polypeptides and uses thereof |
| CA2433841A1 (en) | 2001-01-16 | 2002-08-29 | Mary Ruth Erickson | Gmg-3, gmg-4, and gmg-6 polynucleotides and polypeptides and uses thereof |
| US20030220253A1 (en) * | 2002-03-08 | 2003-11-27 | Lasser Gerald W. | Inhibitors for use in hemostasis |
| JP2008507591A (ja) * | 2004-05-21 | 2008-03-13 | ゼンコー・インコーポレイテッド | 免疫原性が改変されたＣ１ｑファミリーメンバータンパク質 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0679716A4 (en) * | 1993-11-12 | 1999-06-09 | Kenichi Matsubara | GENE SIGNATURE. |
| US5869330A (en) * | 1995-06-05 | 1999-02-09 | Whitehead Institute For Biomedical Research | DNA encoding a novel serum protein produced exclusively in adipocytes |
| HUP0003762A3 (en) * | 1997-07-18 | 2005-11-28 | Zymogenetics Inc | Adipocyte-specific protein homologs |
| NZ527900A (en) * | 1997-12-03 | 2005-02-25 | Genentech Inc | PRO361 polypeptides and nucleic acids with homology to mucin and chitinase |
-
1998
- 1998-07-17 HU HU0003762A patent/HUP0003762A3/hu unknown
- 1998-07-17 DE DE69834643T patent/DE69834643T2/de not_active Expired - Fee Related
- 1998-07-17 AT AT98934630T patent/ATE327328T1/de not_active IP Right Cessation
- 1998-07-17 CA CA002296530A patent/CA2296530A1/en not_active Abandoned
- 1998-07-17 EP EP98934630A patent/EP1002075B1/en not_active Expired - Lifetime
- 1998-07-17 AU AU84113/98A patent/AU743745B2/en not_active Ceased
- 1998-07-17 IL IL13401198A patent/IL134011A0/xx unknown
- 1998-07-17 BR BR9810917-0A patent/BR9810917A/pt not_active Application Discontinuation
- 1998-07-17 CN CNB988089114A patent/CN1201003C/zh not_active Expired - Fee Related
- 1998-07-17 DK DK98934630T patent/DK1002075T3/da active
- 1998-07-17 ES ES98934630T patent/ES2264207T3/es not_active Expired - Lifetime
- 1998-07-17 WO PCT/US1998/014864 patent/WO1999004000A1/en not_active Ceased
- 1998-07-17 RU RU2000103824/13A patent/RU2218402C2/ru not_active IP Right Cessation
- 1998-07-17 PL PL98338139A patent/PL338139A1/xx not_active IP Right Cessation
- 1998-07-17 US US09/118,408 patent/US6265544B1/en not_active Expired - Lifetime
- 1998-07-17 JP JP2000503206A patent/JP3762220B2/ja not_active Expired - Fee Related
- 1998-07-17 KR KR10-2000-7000538A patent/KR100385868B1/ko not_active Expired - Fee Related
-
2000
- 2000-01-17 NO NO20000215A patent/NO20000215L/no not_active Application Discontinuation
-
2001
- 2001-07-23 US US09/911,176 patent/US6518403B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| RU2218402C2 (ru) | 2003-12-10 |
| JP3762220B2 (ja) | 2006-04-05 |
| NO20000215D0 (no) | 2000-01-17 |
| NO20000215L (no) | 2000-03-17 |
| HUP0003762A2 (hu) | 2001-08-28 |
| US20020156243A1 (en) | 2002-10-24 |
| HUP0003762A3 (en) | 2005-11-28 |
| CN1201003C (zh) | 2005-05-11 |
| DK1002075T3 (da) | 2006-09-18 |
| CA2296530A1 (en) | 1999-01-28 |
| WO1999004000A1 (en) | 1999-01-28 |
| AU8411398A (en) | 1999-02-10 |
| ATE327328T1 (de) | 2006-06-15 |
| EP1002075A1 (en) | 2000-05-24 |
| DE69834643T2 (de) | 2007-05-10 |
| ES2264207T3 (es) | 2006-12-16 |
| PL338139A1 (en) | 2000-09-25 |
| US6518403B2 (en) | 2003-02-11 |
| KR20010021973A (ko) | 2001-03-15 |
| AU743745B2 (en) | 2002-02-07 |
| KR100385868B1 (ko) | 2003-06-02 |
| DE69834643D1 (de) | 2006-06-29 |
| IL134011A0 (en) | 2001-04-30 |
| JP2001510045A (ja) | 2001-07-31 |
| CN1272883A (zh) | 2000-11-08 |
| US6265544B1 (en) | 2001-07-24 |
| EP1002075B1 (en) | 2006-05-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR9810917A (pt) | Polipeptìdeo isolado, proteìna de fusão, vetor de expressão, célula cultivada, processo para produzir um polipeptìdeo, composição farmacêutica, anticorpo, proteìna de ligação, polinucleotìdeo isolado, e, sonda de oligonucleotìdeo ou iniciador | |
| Feramisco | Microinjection of fluorescently labeled α-actinin into living fibroblasts | |
| Beyer et al. | Two lactose binding lectins from chicken tissues. Purified lectin from intestine is different from those in liver and muscle. | |
| Savage et al. | Modulation of platelet function through adhesion receptors. A dual role for glycoprotein IIb-IIIa (integrin alpha IIb beta 3) mediated by fibrinogen and glycoprotein Ib-von Willebrand factor. | |
| NO20000934L (no) | Adipocyttspesifikke proteinhomologer | |
| Merenmies et al. | 30-kDa heparin-binding protein of brain (amphoterin) involved in neurite outgrowth. Amino acid sequence and localization in the filopodia of the advancing plasma membrane. | |
| Banerjee et al. | Increased microtubule assembly in bovine brain tubulin lacking the type III isotype of beta-tubulin. | |
| Murphy et al. | Clathrin assembly protein AP-3: The identity of the 155K protein, AP 180, and NP185 and demonstration of a clathrin binding domain | |
| Schwyter et al. | Subtilisin cleavage of actin inhibits in vitro sliding movement of actin filaments over myosin. | |
| Kuznetsov et al. | 18 kDa microtubule‐associated protein: identification as a new light chain (LC‐3) of microtubule‐associated protein 1 (MAP‐1) | |
| KR950032279A (ko) | 인체의 프로그램된 세포 사멸과 관련 있는 펩티드 및 이를 암호하는 디엔에이(dna) | |
| BR0008772A (pt) | Polipeptìdeo isolado, proteìna de fusão, molécula de polinucleotìdeo isolado, vetor de expressão, célula cultivada, anticorpo, processos para produzir uma proteìna e um anticorpo para um polipeptìdeo, para estimular uma resposta imunológica em um mamìfero, para expandir células hematopoiéticas e progenitores de células hematopoiéticas, para reduzir a proliferação de células b ou t neoplásicas e para detectar a presença de rna de ligando zalfa11 e de ligando zalfal11 em uma amostra biológica | |
| DE69619493D1 (de) | Polypeptid-dendrimer komplexe | |
| Van Eldik et al. | Interaction of calmodulin and other calcium-modulated proteins with mammalian and arthropod junctional membrane proteins | |
| DE69536123D1 (de) | Fusionsprotein dass bpTK7 enthält | |
| Nakai et al. | Transformation of BALB/3T3 cells by simian virus 40 causes a decreased synthesis of a collagen-binding heat-shock protein (hsp47). | |
| BR9509172A (pt) | Proteina de via de complemento nativa sequéncia de dna construção de dna conjugado uso de uma proteína processo para reduzir proteina de via de complemento em um mamifero e formulação farmacéutica | |
| Tedeschi et al. | Purification and primary structure of a new bovine spermadhesin | |
| ATE372384T1 (de) | Protein-tyrosin-phosphatase ptp-s31 | |
| Isaacs et al. | Association of titin and myosin heavy chain in developing skeletal muscle. | |
| BR9913942A (pt) | Polinucleotìdeo e polipeptìdeo isolado, vetor de expressão, célula cultivada, constructo de dna codificador de uma proteìna de fusão, processos de produção de uma proteìna, de fusão de um polipeptìdeo e de um anticorpo para o polipeptìdeo e de detecção, em uma amostra de teste, da presença de um modulador da atividade da proteìna zalpha11 e de um ligante de receptor zalpha11 dentro de uma amostra de teste, e, anticorpo | |
| Schwanbeck et al. | Cdc2 and Mitogen-activated Protein Kinases Modulate DNA Binding Properties of the Putative Transcriptional RegulatorChironomus High Mobility Group Protein I | |
| Kumagai et al. | Disulfide‐bonding between Drosophila laminin β and γ chains is essential for α chain to form αβγ trimer | |
| Aizawa et al. | Limited chymotryptic digestion of bovine adrenal 190,000-Mr microtubule-associated protein and preparation of a 27,000-Mr fragment which stimulates microtubule assembly. | |
| Seagar et al. | Photoaffinity labeling of components of the apamin-sensitive K+ channel in neuronal membranes. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: DE ACORDO COM O ART 36 DA LPI (LEI 9.279/96) 2O, O PEDIDO VOLTA A EXAME SENDO CONSIDERADO NAO PATENTEAVEL PELAS RAZOES EXPOSTAS NO PARECER TECNICO ANTERIOR. |