RU2218402C2 - Выделенный полипептид, имеющий гомологию относительно комплемент родственного белка адипоцитов (варианты), гибридный белок (варианты), экспрессирующий вектор, способ получения полипептида, поликлональное антитело, фрагмент выделенного полинуклеотида (варианты) - Google Patents

Выделенный полипептид, имеющий гомологию относительно комплемент родственного белка адипоцитов (варианты), гибридный белок (варианты), экспрессирующий вектор, способ получения полипептида, поликлональное антитело, фрагмент выделенного полинуклеотида (варианты) Download PDF

Info

Publication number
RU2218402C2
RU2218402C2 RU2000103824/13A RU2000103824A RU2218402C2 RU 2218402 C2 RU2218402 C2 RU 2218402C2 RU 2000103824/13 A RU2000103824/13 A RU 2000103824/13A RU 2000103824 A RU2000103824 A RU 2000103824A RU 2218402 C2 RU2218402 C2 RU 2218402C2
Authority
RU
Russia
Prior art keywords
seq
amino acid
acid sequence
polypeptide
positions
Prior art date
Application number
RU2000103824/13A
Other languages
English (en)
Russian (ru)
Other versions
RU2000103824A (ru
Inventor
Пол О. ШЕППАРД
Original Assignee
Займодженетикс, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Займодженетикс, Инк. filed Critical Займодженетикс, Инк.
Publication of RU2000103824A publication Critical patent/RU2000103824A/ru
Application granted granted Critical
Publication of RU2218402C2 publication Critical patent/RU2218402C2/ru

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
RU2000103824/13A 1997-07-18 1998-07-17 Выделенный полипептид, имеющий гомологию относительно комплемент родственного белка адипоцитов (варианты), гибридный белок (варианты), экспрессирующий вектор, способ получения полипептида, поликлональное антитело, фрагмент выделенного полинуклеотида (варианты) RU2218402C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5315497P 1997-07-18 1997-07-18
US60/053,154 1997-07-18

Publications (2)

Publication Number Publication Date
RU2000103824A RU2000103824A (ru) 2001-12-10
RU2218402C2 true RU2218402C2 (ru) 2003-12-10

Family

ID=21982287

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2000103824/13A RU2218402C2 (ru) 1997-07-18 1998-07-17 Выделенный полипептид, имеющий гомологию относительно комплемент родственного белка адипоцитов (варианты), гибридный белок (варианты), экспрессирующий вектор, способ получения полипептида, поликлональное антитело, фрагмент выделенного полинуклеотида (варианты)

Country Status (18)

Country Link
US (2) US6265544B1 (https=)
EP (1) EP1002075B1 (https=)
JP (1) JP3762220B2 (https=)
KR (1) KR100385868B1 (https=)
CN (1) CN1201003C (https=)
AT (1) ATE327328T1 (https=)
AU (1) AU743745B2 (https=)
BR (1) BR9810917A (https=)
CA (1) CA2296530A1 (https=)
DE (1) DE69834643T2 (https=)
DK (1) DK1002075T3 (https=)
ES (1) ES2264207T3 (https=)
HU (1) HUP0003762A3 (https=)
IL (1) IL134011A0 (https=)
NO (1) NO20000215L (https=)
PL (1) PL338139A1 (https=)
RU (1) RU2218402C2 (https=)
WO (1) WO1999004000A1 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020137890A1 (en) * 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
HUP0003762A3 (en) * 1997-07-18 2005-11-28 Zymogenetics Inc Adipocyte-specific protein homologs
US6566499B1 (en) * 1997-07-18 2003-05-20 Zymogenetics, Inc. Adipocyte-specific protein homologs
FR2767135B1 (fr) 1997-08-06 2002-07-12 Genset Sa Recepteur complexe lsr, activite, clonage, et application au diagnostic, a la prevention et/ou au traitement de d'obesite et des risques ou complications associes
US20030129691A1 (en) * 1998-02-09 2003-07-10 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US7300774B1 (en) 1999-12-09 2007-11-27 The Regents Of The University Of California Multimeric fusion proteins of the TNF superfamily ligands
DE60004015T2 (de) * 1999-02-19 2004-04-15 Zymogenetics, Inc., Seattle Inhibitoren für homöostase und immunfunktion
US6544946B1 (en) * 1999-02-19 2003-04-08 Zymogenetics, Inc. Inhibitors for use in hemostasis and immune function
US20040014650A1 (en) * 2002-07-17 2004-01-22 Sheppard Paul D Methods for enhancing wound repair
AU5037100A (en) * 1999-05-27 2000-12-18 Zymogenetics Inc. Adipocyte complement related protein homolog zacrp6
JP2003501027A (ja) * 1999-05-27 2003-01-14 ザイモジェネティクス，インコーポレイティド 脂肪細胞補体関連タンパク質同族体ｚａｃｒｐ５
US20050042719A1 (en) * 1999-05-27 2005-02-24 Zymogenetics, Inc. Adipocyte complement related protein homolog zacrp5
DE60043367D1 (de) * 1999-06-15 2009-12-31 Genentech Inc Sekretierte und Transmembran-Polypeptide sowie Nukleinsäuren zu deren Kodierung
MXPA01013444A (es) * 1999-07-01 2002-07-22 Zymogenetics Inc Proteina secretada zacrp4.
DE19963859A1 (de) * 1999-12-30 2001-07-12 Apotech Res & Dev Ltd Bi- oder Oligomer eines Di-, Tri-, Quattro- oder Pentamers von rekombinanten Fusionsproteinen
WO2002070704A2 (en) * 2000-11-29 2002-09-12 Zymogenetics, Inc. Adipocyte complement related protein zacrp11
EP1421190A2 (en) 2001-01-16 2004-05-26 Genset Metabolic gene polynucleotides and polypeptides and uses thereof
CA2433841A1 (en) 2001-01-16 2002-08-29 Mary Ruth Erickson Gmg-3, gmg-4, and gmg-6 polynucleotides and polypeptides and uses thereof
US20030220253A1 (en) * 2002-03-08 2003-11-27 Lasser Gerald W. Inhibitors for use in hemostasis
JP2008507591A (ja) * 2004-05-21 2008-03-13 ゼンコー・インコーポレイテッド 免疫原性が改変されたＣ１ｑファミリーメンバータンパク質

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0679716A4 (en) * 1993-11-12 1999-06-09 Kenichi Matsubara GENE SIGNATURE.
US5869330A (en) * 1995-06-05 1999-02-09 Whitehead Institute For Biomedical Research DNA encoding a novel serum protein produced exclusively in adipocytes
HUP0003762A3 (en) * 1997-07-18 2005-11-28 Zymogenetics Inc Adipocyte-specific protein homologs
NZ527900A (en) * 1997-12-03 2005-02-25 Genentech Inc PRO361 polypeptides and nucleic acids with homology to mucin and chitinase

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NAKANO Y. et al., Isolation and characterisation. of GBP28, a novel gelatin-binding protein purified from human plasma, Journal of Biochemistry, vol. 120, 1996, p. 803-812. *

Also Published As

Publication number Publication date
JP3762220B2 (ja) 2006-04-05
NO20000215D0 (no) 2000-01-17
NO20000215L (no) 2000-03-17
HUP0003762A2 (hu) 2001-08-28
US20020156243A1 (en) 2002-10-24
HUP0003762A3 (en) 2005-11-28
CN1201003C (zh) 2005-05-11
DK1002075T3 (da) 2006-09-18
CA2296530A1 (en) 1999-01-28
WO1999004000A1 (en) 1999-01-28
AU8411398A (en) 1999-02-10
ATE327328T1 (de) 2006-06-15
EP1002075A1 (en) 2000-05-24
DE69834643T2 (de) 2007-05-10
ES2264207T3 (es) 2006-12-16
PL338139A1 (en) 2000-09-25
US6518403B2 (en) 2003-02-11
KR20010021973A (ko) 2001-03-15
AU743745B2 (en) 2002-02-07
BR9810917A (pt) 2000-08-15
KR100385868B1 (ko) 2003-06-02
DE69834643D1 (de) 2006-06-29
IL134011A0 (en) 2001-04-30
JP2001510045A (ja) 2001-07-31
CN1272883A (zh) 2000-11-08
US6265544B1 (en) 2001-07-24
EP1002075B1 (en) 2006-05-24

Similar Documents

Publication Publication Date Title
RU2218402C2 (ru) Выделенный полипептид, имеющий гомологию относительно комплемент родственного белка адипоцитов (варианты), гибридный белок (варианты), экспрессирующий вектор, способ получения полипептида, поликлональное антитело, фрагмент выделенного полинуклеотида (варианты)
Hartmann et al. A tetrameric complex of membrane proteins in the endoplasmic reticulum
Geisler et al. Hybrid character of a large neurofilament protein (NF‐M): intermediate filament type sequence followed by a long and acidic carboxy‐terminal extension.
RU2000103824A (ru) Адипоцит-специфические белковые гомологи
Shirayoshi et al. Cadherin cell adhesion molecules with distinct binding specificities share a common structure.
CA2339889A1 (en) Identification of specific binding partners binding to (poly)peptides encoded by genomic dna fragments or ests
WO1999055868A3 (en) Fizz proteins
RU2007127624A (ru) Рекомбинантная экспрессия белков в двухцепочечной форме с дисульфидным мостиком
GB0219459D0 (en) Chimeric protein and oligomer thereof
AU2020329616B2 (en) Caspase-2 variants
Harumiya et al. EBP-37, a new elastin-binding protein in human plasma: structural similarity to ficolins, transforming growth factor-β1-binding proteins
WO2000026244A3 (en) A novel tumor necrosis factor family member, drl, and related compositions and methods
CA2302808A1 (en) 50 human secreted proteins
KR870001311A (ko) 단백질 및 폴리펩티드의 제조 방법
JP3781771B2 (ja) 新規ポリペプチド及びそれをコードするｄｎａ
Pohlner et al. A plasmid system for high-level expression and in vitro processing of recombinant proteins
RU2007124731A (ru) Грамположительные бактерии, продуцирующие рекомбинантные белки
BG101226A (bg) Метод за производство на модифициран инхибитор палидипин на колагениндуцирано тромбоцитно натрупване
EP0845004A1 (en) Epitope tagging system
CN102348800A (zh) 融合蛋白、其制备方法及其在重组蛋白表达系统中的应用
Zaltash et al. Secondary structure and limited proteolysis give experimental evidence that the precursor of pulmonary surfactant protein B contains three saposin-like domains
CN116875567A (zh) 一种孝顺竹来源的蛋白连接酶原或酶及其应用
JP6828291B2 (ja) ヒトＦｃＲｎをコードするポリヌクレオチドおよび当該ポリヌクレオチドを利用したヒトＦｃＲｎの製造方法
CN111349585B (zh) 一种海洋来源的胶原蛋白膨胀蛋白酶vp9及其编码基因与应用
CA2374513A1 (en) Il-1 eta dna and polypeptides

Legal Events

Date Code Title Description
MM4A The patent is invalid due to non-payment of fees

Effective date: 20070718