CN119954801A - Tau蛋白靶向化合物及相关使用方法 - Google Patents

Tau蛋白靶向化合物及相关使用方法 Download PDF

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Publication number
CN119954801A
CN119954801A CN202510130079.8A CN202510130079A CN119954801A CN 119954801 A CN119954801 A CN 119954801A CN 202510130079 A CN202510130079 A CN 202510130079A CN 119954801 A CN119954801 A CN 119954801A
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alkyl
optionally substituted
ptm
group
methyl
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安德鲁·P·克鲁
迈克尔·贝尔林
H·董
亚力克西·伊先科
安格拉·M·卡卡切
朱利安·T·钱德勒
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Arvinas Inc
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Arvinas Inc
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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CN202510130079.8A 2019-07-17 2020-07-17 Tau蛋白靶向化合物及相关使用方法 Pending CN119954801A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201962875500P 2019-07-17 2019-07-17
US62/875,500 2019-07-17
CN202080063078.1A CN114867727B (zh) 2019-07-17 2020-07-17 Tau蛋白靶向化合物及相关使用方法
PCT/US2020/042645 WO2021011913A1 (en) 2019-07-17 2020-07-17 Tau-protein targeting compounds and associated methods of use

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US (2) US11912699B2 (enExample)
EP (1) EP3999182A1 (enExample)
JP (2) JP7548992B2 (enExample)
CN (2) CN119954801A (enExample)
WO (1) WO2021011913A1 (enExample)

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CN116283512B (zh) * 2023-02-24 2025-04-25 博诺康源(北京)药业科技有限公司 一种合成维兰特罗及其盐的方法
WO2024182633A2 (en) * 2023-03-01 2024-09-06 The Regents Of The University Of California Targeted dephosphorylation of tau
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