CN1198166A - 检测牙周病的遗传素因 - Google Patents

检测牙周病的遗传素因 Download PDF

Info

Publication number
CN1198166A
CN1198166A CN96197316A CN96197316A CN1198166A CN 1198166 A CN1198166 A CN 1198166A CN 96197316 A CN96197316 A CN 96197316A CN 96197316 A CN96197316 A CN 96197316A CN 1198166 A CN1198166 A CN 1198166A
Authority
CN
China
Prior art keywords
seq
genetic polymorphism
dna
allelotrope
severity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN96197316A
Other languages
English (en)
Chinese (zh)
Inventor
肯尼思S·科恩曼
G·W·杜夫
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medical Science Systems Inc
Original Assignee
Medical Science Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Science Systems Inc filed Critical Medical Science Systems Inc
Publication of CN1198166A publication Critical patent/CN1198166A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN96197316A 1995-08-03 1996-08-02 检测牙周病的遗传素因 Pending CN1198166A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/510,696 1995-08-03
US08/510,696 US5686246A (en) 1995-08-03 1995-08-03 Detecting genetic predisposition to periodontal disease

Publications (1)

Publication Number Publication Date
CN1198166A true CN1198166A (zh) 1998-11-04

Family

ID=24031795

Family Applications (1)

Application Number Title Priority Date Filing Date
CN96197316A Pending CN1198166A (zh) 1995-08-03 1996-08-02 检测牙周病的遗传素因

Country Status (25)

Country Link
US (1) US5686246A (enExample)
EP (2) EP0853630A4 (enExample)
JP (1) JP4042811B2 (enExample)
KR (1) KR19990036067A (enExample)
CN (1) CN1198166A (enExample)
AR (1) AR003182A1 (enExample)
AT (1) ATE207927T1 (enExample)
AU (1) AU719965B2 (enExample)
BR (1) BR9604044A (enExample)
CA (1) CA2228424C (enExample)
DE (1) DE69616478T2 (enExample)
DK (1) DK0769560T3 (enExample)
ES (1) ES2166866T3 (enExample)
ID (1) ID17246A (enExample)
IL (1) IL123053A (enExample)
IS (1) IS4653A (enExample)
MX (1) MX9800941A (enExample)
MY (1) MY132156A (enExample)
NO (1) NO980439L (enExample)
NZ (1) NZ315836A (enExample)
PT (1) PT769560E (enExample)
SI (1) SI9620098A (enExample)
TW (1) TW406130B (enExample)
WO (1) WO1997006180A1 (enExample)
ZA (1) ZA966585B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100453650C (zh) * 2002-09-30 2009-01-21 诺瓦提斯公司 预测免疫抑制治疗期间胆固醇升高的方法

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6951721B2 (en) * 1996-02-12 2005-10-04 Gene Logic Inc. Method for determining the haplotype of a human BRCA1 gene
GB9621129D0 (en) 1996-10-10 1996-11-27 Duff Gordon W Detecting genetic predisposition to sight-threatening diabetic retinopathy
US6210877B1 (en) * 1997-03-10 2001-04-03 Interleukin Genetics, Inc. Prediction of coronary artery disease
US6524795B1 (en) * 1997-03-10 2003-02-25 Interleukin Genetics, Inc. Diagnostics for cardiovascular disorders
US7820383B2 (en) 1997-03-10 2010-10-26 Interleukin Genetics, Inc. Method for diagnosing myocardial infarction
GB9723553D0 (en) * 1997-11-07 1998-01-07 Duff Gordon W Prediction of the risk of chronic obstructive airway disease
GB9711040D0 (en) 1997-05-29 1997-07-23 Duff Gordon W Prediction of inflammatory disease
US20050282198A1 (en) * 1997-05-29 2005-12-22 Interleukin Genetics, Inc. Diagnostics and therapeutics for diseases associated with an IL-1 inflammatory haplotype
AU9217198A (en) * 1997-09-03 1999-03-22 Oncormed Method for predicting prognosis and treatment response for genetically based abnormalities
IL135957A0 (en) * 1997-11-07 2001-05-20 Interleukin Genetics Inc Diagnostics and therapeutics for chronic obstructive airway disease
US6746839B1 (en) 1998-01-12 2004-06-08 Interleukin Genetics, Inc. Diagnostics and therapeutics for an obstructive airway disease
US6130042A (en) * 1998-03-05 2000-10-10 The United States Of America As Represented By The Department Of Health And Human Services Compositions and methods for diagnosing periodontal disease
US20050032077A1 (en) * 1998-03-10 2005-02-10 Duff Gordon W. Detecting genetic predisposition to sight-threatening diabetic retinopathy
WO1999054707A2 (en) * 1998-04-21 1999-10-28 Interleukin Genetics, Inc. Fetal testing for prediction of low birth weight
US6733967B1 (en) 1998-04-21 2004-05-11 Interleukin Genetics, Inc. Fetal testing for prediction of low birth weight
US6251598B1 (en) * 1998-10-30 2001-06-26 Interleukin Genetics, Inc. Methods for diagnosing sepsis
US20090023147A1 (en) * 1999-08-30 2009-01-22 Kenneth Kornman Diagnostics and therapeutics for osteoporosis
US6225069B1 (en) * 2000-02-29 2001-05-01 The Board Of Trustees Of The University Of Arkansas Methods to identify genetic predisposition to alzheimer's disease
US20030124524A1 (en) * 2000-06-23 2003-07-03 Kenneth Kornman Screening assays for identifying modulators of the inflammatory or immune response
US7054758B2 (en) * 2001-01-30 2006-05-30 Sciona Limited Computer-assisted means for assessing lifestyle risk factors
DE10112348A1 (de) * 2001-03-13 2002-10-02 Antje Roetger Nukleotidträger zur Diagnose und Therapie oraler Erkrankungen
US20030152947A1 (en) * 2001-06-15 2003-08-14 Crossman David C. Methods for detecting and treating the early onset of aging-related conditions
EP1463745A4 (en) * 2001-11-19 2007-11-07 Interleukin Genetics Inc FUNCTIONAL POLYMORPHISMS OF THE INTERLEUKIN-1 SITE AFFECTING TRANSCRIPTION AND SUSCEPTIBILITY TO INFLAMMATORY AND INFECTIOUS DISEASES
US20080311581A1 (en) * 2001-11-19 2008-12-18 David Wyllie Functional polymorphisms of the interleukin-1 locus affecting transcription and susceptibility to inflammatory and infectious diseases
US20070264645A1 (en) * 2002-01-25 2007-11-15 Kenneth Kornman IL-1 gene cluster and associated inflammatory polymorphisms and haplotypes
US20030148288A1 (en) * 2002-02-01 2003-08-07 Yi-Wei Tang Colorimetric genetic test for clinically significant TNF polymorphism and methods of use thereof
US20040229228A1 (en) * 2002-07-25 2004-11-18 Northwestern University Il-1 genotype in early kidney allograft rejection
EP1680513B1 (en) * 2003-08-08 2010-12-01 Interleukin Genetics, Inc. Diagnostic for osteoporosis
US20070003947A1 (en) * 2005-01-18 2007-01-04 Decarlo Arthur A Detecting genetic risk for periodontal disease
EP1851245B1 (en) 2005-01-26 2012-10-10 Amgen Fremont Inc. Antibodies against interleukin-1 beta
US8105775B2 (en) * 2005-10-25 2012-01-31 Interleukin Genetics, Inc. IL-1 gene cluster and associated inflammatory polymorphisms and haplotypes
WO2008060627A2 (en) * 2006-11-15 2008-05-22 Interleukin Genetics, Inc. The il-1 gene cluster, insulin resistance and coronary artery disease associated polymorphisms and haplotypes and methods of using same
US7925192B2 (en) * 2007-09-04 2011-04-12 Ricoh Company, Ltd. Developing roller, developing device, process cartridge, and image forming apparatus
US20090170105A1 (en) * 2007-11-08 2009-07-02 Interleukin Genetics, Inc. Diagnostics for Aging-Related Dermatologic Disorders
EP2304052A2 (en) * 2008-05-02 2011-04-06 Interleukin Genetics, Inc. Detecting genetic predisposition to osteoarthritis associated conditions
ES2708826T3 (es) 2008-05-02 2019-04-11 Orig3N Inc Detección de la predisposición genética a afecciones asociadas a la osteoartritis
SG191078A1 (en) 2010-12-09 2013-07-31 Interleukin Genetics Inc Improved method and kit for determining severity and progression of periodontal disease
CA3011363A1 (en) 2016-01-12 2017-07-20 Interleukin Genetics, Inc. Methods for predicting response to treatment
US10329620B2 (en) 2017-01-12 2019-06-25 Cardioforecast Ltd. Methods and kits for treating cardiovascular disease
KR101894018B1 (ko) * 2017-02-09 2018-08-31 주식회사 테라젠이텍스 치주 질환의 위험도를 예측하기 위한 조성물, 마이크로어레이, 및 키트, 및 이를 이용한 방법
CA3142662A1 (en) 2019-06-06 2020-12-10 Sitokine Limited Compositions and methods for treating lung, colorectal and breast cancer
WO2021028469A1 (en) 2019-08-12 2021-02-18 Sitokine Limited Compositions and methods for treating cytokine release syndrome and neurotoxicity
WO2021205013A1 (en) 2020-04-09 2021-10-14 Sitokine Limited Compositions and methods for treating covid-19

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5110920A (en) * 1982-01-22 1992-05-05 Cetus Corporation HLA typing method and DNA probes used therein
US4582788A (en) * 1982-01-22 1986-04-15 Cetus Corporation HLA typing method and cDNA probes used therein
DE3377363D1 (en) * 1982-03-31 1988-08-18 Ajinomoto Kk Gene coding for interleukin-2 polypeptide, recombinant dna carrying said gene, cell lines possessing the recombinant dna,and method for producing interleukin-2 using said cells
US4666828A (en) * 1984-08-15 1987-05-19 The General Hospital Corporation Test for Huntington's disease
US4801531A (en) * 1985-04-17 1989-01-31 Biotechnology Research Partners, Ltd. Apo AI/CIII genomic polymorphisms predictive of atherosclerosis
US5206344A (en) * 1985-06-26 1993-04-27 Cetus Oncology Corporation Interleukin-2 muteins and polymer conjugation thereof
US4772685A (en) * 1985-10-02 1988-09-20 Merck & Co., Inc. Immunogenic peptides of human interleukin-1 and the corresponding anti-peptide antibodies
US4992367A (en) * 1986-05-12 1991-02-12 Hoffmann-La Roche Inc. Enhanced expression of human interleukin-2 in mammalian cells
US5268267A (en) * 1987-08-21 1993-12-07 The General Hospital Corporation Method for diagnosing small cell carcinoma
US5158871A (en) * 1988-02-12 1992-10-27 University Of Connecticut Method of using magnetic particles for isolating, collecting and assaying diagnostic ligates
US5272057A (en) * 1988-10-14 1993-12-21 Georgetown University Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
US5215895A (en) * 1989-11-22 1993-06-01 Genetics Institute, Inc. Dna encoding a mammalian cytokine, interleukin-11
US5328829A (en) * 1990-07-05 1994-07-12 Forsyth Dental Infirmary For Children Method of determining sites of active periodontal disease

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100453650C (zh) * 2002-09-30 2009-01-21 诺瓦提斯公司 预测免疫抑制治疗期间胆固醇升高的方法

Also Published As

Publication number Publication date
EP0853630A4 (en) 1999-10-27
US5686246A (en) 1997-11-11
JP4042811B2 (ja) 2008-02-06
DE69616478T2 (de) 2002-08-08
EP0853630A1 (en) 1998-07-22
SI9620098A (sl) 1998-10-31
WO1997006180A1 (en) 1997-02-20
DK0769560T3 (da) 2002-02-18
KR19990036067A (ko) 1999-05-25
BR9604044A (pt) 1998-06-09
JP2001517067A (ja) 2001-10-02
ES2166866T3 (es) 2002-05-01
ID17246A (id) 1997-12-11
NO980439L (no) 1998-03-13
AR003182A1 (es) 1998-07-08
IS4653A (is) 1998-01-19
MY132156A (en) 2007-09-28
NO980439D0 (no) 1998-02-02
ATE207927T1 (de) 2001-11-15
EP0769560A3 (en) 1999-11-24
EP0769560A2 (en) 1997-04-23
IL123053A (en) 2000-01-31
EP0769560B1 (en) 2001-10-31
MX9800941A (es) 1998-10-31
ZA966585B (en) 1997-02-26
IL123053A0 (en) 1998-12-06
PT769560E (pt) 2002-04-29
CA2228424A1 (en) 1997-02-20
AU719965B2 (en) 2000-05-18
AU6763396A (en) 1997-03-05
TW406130B (en) 2000-09-21
NZ315836A (en) 1999-10-28
CA2228424C (en) 2005-12-27
DE69616478D1 (de) 2001-12-06

Similar Documents

Publication Publication Date Title
CN1198166A (zh) 检测牙周病的遗传素因
CN100347313C (zh) 检测骨质疏松症的遗传素因
CN1177059C (zh) 与il-1基因座多态性相关之炎性疾病的预测方法
CN1665937A (zh) 测定甲基化图谱的方法和组合物
JP2000508912A (ja) 多型形態と複数の表現型との相関付け
CN101054601A (zh) 一种检测细胞色素p450酶系突变位点的寡核苷酸探针及基因芯片
CN1932041A (zh) 对于赤鹿、梅花鹿、马鹿以及驯鹿的基因特异的引物以及利用该引物识别鹿茸品种的方法
CN1753903A (zh) 影响转录和对炎性和传染性疾病的敏感性的白细胞介素－1基因座的功能多态性
CN1187456C (zh) CpG岛甲基化检测试剂盒及其应用
CN1285002A (zh) 根据人呼吸道胰蛋白酶基因多态性分析体质
Ouryouji et al. Analysis of mutations in the amelogenin and the enamelin genes in severe caries in Japanese pediatric patients
CN1282338A (zh) 编码前神经肽y原突变体,一种信号肽的突变体,的dna分子及其应用
CN1202205A (zh) 冠痉挛相关性疾病的诊断
CN1257987C (zh) 利用等位基因特异性pcr检测与鸡生长发育和产蛋性状相关基因的分子标记方法及其应用
CN1763196A (zh) 基因突变类型及基因测序方法
CN100342011C (zh) 猪免疫性状相关基因psmc5的克隆及其应用
CN1442487A (zh) 犬尿氨酸水解酶多态性及其诊断用途
CN1976942A (zh) 用于鉴定fc受体多态性的核酸分析方法
CN1300337C (zh) 一种细胞因子基因型检测芯片及其用途
CN1699595A (zh) 检测与人类遗传性耳聋相关的wfs1基因突变的方法
CN1291038C (zh) 一种21号染色体数目的快速检测方法
CN1548552A (zh) 精神分裂症易感基因检测方法及易感基因和用途
CN1683554A (zh) 与鸡产蛋量相关的mhc b－lb基因pcr－rflp标记
CN101065499A (zh) 通过多重pcr进行rhd和abo基因分型
CN1844408A (zh) 一种筛查唐氏综合征高危胎儿的方法

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C53 Correction of patent of invention or patent application
CB02 Change of applicant information

Applicant after: Medical Science Systems, Inc.

Applicant before: Medical Science Systems, Inc.

Applicant before: Kenneth S. Kornman

COR Change of bibliographic data

Free format text: CORRECT: APPLICANT; FROM: MEDICAL SCIENCE SYSTEMS, INC.; KENNETH S. KORNMAN TO: MEDICAL SCIENCE SYSTEMS, INC.

C01 Deemed withdrawal of patent application (patent law 1993)
WD01 Invention patent application deemed withdrawn after publication