CN1171582C - 口服药用延释剂型 - Google Patents

口服药用延释剂型 Download PDF

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Publication number
CN1171582C
CN1171582C CNB988136163A CN98813616A CN1171582C CN 1171582 C CN1171582 C CN 1171582C CN B988136163 A CNB988136163 A CN B988136163A CN 98813616 A CN98813616 A CN 98813616A CN 1171582 C CN1171582 C CN 1171582C
Authority
CN
China
Prior art keywords
dosage form
core material
atpase inhibitor
omeprazole
tablet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB988136163A
Other languages
English (en)
Chinese (zh)
Other versions
CN1284866A (zh
Inventor
P��-G������ϣ��
P·－G·卡雷希尔
±���
P·J·伦德贝里
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of CN1284866A publication Critical patent/CN1284866A/zh
Application granted granted Critical
Publication of CN1171582C publication Critical patent/CN1171582C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CNB988136163A 1997-12-22 1998-12-17 口服药用延释剂型 Expired - Fee Related CN1171582C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9704869A SE9704869D0 (sv) 1997-12-22 1997-12-22 New pharmaceutical formulaton II
SE970488698 1997-12-22

Publications (2)

Publication Number Publication Date
CN1284866A CN1284866A (zh) 2001-02-21
CN1171582C true CN1171582C (zh) 2004-10-20

Family

ID=20409571

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB988136163A Expired - Fee Related CN1171582C (zh) 1997-12-22 1998-12-17 口服药用延释剂型

Country Status (38)

Country Link
US (1) US6605303B1 (enExample)
EP (1) EP1043976B1 (enExample)
JP (1) JP4865945B2 (enExample)
KR (2) KR20060097069A (enExample)
CN (1) CN1171582C (enExample)
AR (1) AR017201A1 (enExample)
AT (1) ATE312602T1 (enExample)
AU (1) AU759634B2 (enExample)
BG (1) BG65028B1 (enExample)
BR (1) BR9814378A (enExample)
CA (1) CA2315261C (enExample)
CY (1) CY1106072T1 (enExample)
CZ (1) CZ299228B6 (enExample)
DE (1) DE69832816T2 (enExample)
DK (1) DK1043976T3 (enExample)
DZ (1) DZ2685A1 (enExample)
EE (1) EE04901B1 (enExample)
ES (1) ES2252875T3 (enExample)
HR (1) HRP20000380B1 (enExample)
HU (1) HUP0101437A3 (enExample)
IL (2) IL136827A0 (enExample)
IS (1) IS5524A (enExample)
MA (1) MA26576A1 (enExample)
MY (1) MY126555A (enExample)
NO (1) NO20003218L (enExample)
NZ (1) NZ505127A (enExample)
PL (1) PL193776B1 (enExample)
RU (1) RU2214232C2 (enExample)
SA (1) SA99191077B1 (enExample)
SE (1) SE9704869D0 (enExample)
SK (1) SK284988B6 (enExample)
TN (1) TNSN98229A1 (enExample)
TR (1) TR200001981T2 (enExample)
TW (1) TWI249410B (enExample)
UA (1) UA69397C2 (enExample)
WO (1) WO1999032091A1 (enExample)
YU (1) YU36700A (enExample)
ZA (1) ZA9811239B (enExample)

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ATE500815T1 (de) 1997-12-08 2011-03-15 Dietrich Rango Neue suppositoriumsform mit säureempfindlichem wirkstoff
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JP4732696B2 (ja) 2002-04-09 2011-07-27 フラメル・テクノロジー 活性成分の改変された放出のための、マイクロカプセルの水性懸濁液形態での経口医薬品製剤
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KR100591142B1 (ko) * 2005-11-04 2006-06-20 지엘팜텍 주식회사 파록세틴을 활성물질로 함유하는 장용성 서방형 정제
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Also Published As

Publication number Publication date
KR20010033428A (ko) 2001-04-25
CZ20002314A3 (cs) 2000-11-15
HK1034455A1 (en) 2001-10-26
ATE312602T1 (de) 2005-12-15
AU759634B2 (en) 2003-04-17
IL136827A (en) 2007-05-15
TWI249410B (en) 2006-02-21
SK284988B6 (sk) 2006-04-06
BR9814378A (pt) 2000-10-10
TR200001981T2 (tr) 2000-11-21
YU36700A (sh) 2003-01-31
US6605303B1 (en) 2003-08-12
EP1043976A1 (en) 2000-10-18
PL193776B1 (pl) 2007-03-30
IS5524A (is) 2000-06-08
CZ299228B6 (cs) 2008-05-21
BG104620A (en) 2001-04-30
CN1284866A (zh) 2001-02-21
AR017201A1 (es) 2001-08-22
AU1991299A (en) 1999-07-12
DZ2685A1 (fr) 2003-03-29
WO1999032091A1 (en) 1999-07-01
RU2214232C2 (ru) 2003-10-20
MY126555A (en) 2006-10-31
SE9704869D0 (sv) 1997-12-22
EE04901B1 (et) 2007-10-15
EE200000383A (et) 2001-12-17
NZ505127A (en) 2003-02-28
HRP20000380A2 (en) 2001-06-30
TNSN98229A1 (fr) 2005-03-15
SA99191077B1 (ar) 2006-07-11
DE69832816D1 (de) 2006-01-19
MA26576A1 (fr) 2004-12-20
DK1043976T3 (da) 2006-03-20
HRP20000380B1 (en) 2007-08-31
JP2001526211A (ja) 2001-12-18
ZA9811239B (en) 1999-06-22
NO20003218D0 (no) 2000-06-21
KR100755154B1 (ko) 2007-09-04
HUP0101437A2 (hu) 2001-10-28
EP1043976B1 (en) 2005-12-14
CA2315261A1 (en) 1999-07-01
PL341428A1 (en) 2001-04-09
SK8072000A3 (en) 2001-01-18
IL136827A0 (en) 2001-06-14
UA69397C2 (uk) 2004-09-15
ES2252875T3 (es) 2006-05-16
JP4865945B2 (ja) 2012-02-01
CA2315261C (en) 2008-02-12
BG65028B1 (bg) 2006-12-29
NO20003218L (no) 2000-08-22
CY1106072T1 (el) 2011-06-08
HUP0101437A3 (en) 2003-01-28
DE69832816T2 (de) 2006-08-31
KR20060097069A (ko) 2006-09-13

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