CN1167681C - 稠合二氢吲哚衍生物及其作为5ht特别是5ht2c受体配体的用途 - Google Patents

稠合二氢吲哚衍生物及其作为5ht特别是5ht2c受体配体的用途 Download PDF

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CN1167681C
CN1167681C CNB008115168A CN00811516A CN1167681C CN 1167681 C CN1167681 C CN 1167681C CN B008115168 A CNB008115168 A CN B008115168A CN 00811516 A CN00811516 A CN 00811516A CN 1167681 C CN1167681 C CN 1167681C
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compound
indole
pharmaceutically acceptable
acceptable salt
mixture
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CN1379761A (zh
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J��R��A������˹
J·R·A·罗菲
P��ά����ɭ
J·E·P·达维森
H·L·曼塞尔
��������ķ������
R·J·哈姆利恩
�ǵ�˹
D·R·亚当斯
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Ligand UK Research Ltd
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Vernalis Research Ltd
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CNB008115168A 1999-08-11 2000-08-04 稠合二氢吲哚衍生物及其作为5ht特别是5ht2c受体配体的用途 Expired - Fee Related CN1167681C (zh)

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GB9918965.6 1999-08-11
GBGB9918965.6A GB9918965D0 (en) 1999-08-11 1999-08-11 Chemical compounds xxi

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CN1379761A CN1379761A (zh) 2002-11-13
CN1167681C true CN1167681C (zh) 2004-09-22

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US (10) US6962939B1 (enExample)
EP (1) EP1202964B1 (enExample)
JP (1) JP2003507366A (enExample)
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CN (1) CN1167681C (enExample)
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AT (1) ATE306470T1 (enExample)
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GB9918965D0 (en) * 1999-08-11 1999-10-13 Cerebrus Ltd Chemical compounds xxi
SE0004245D0 (sv) 2000-11-20 2000-11-20 Pharmacia Ab Novel compounds and their use
JP4204315B2 (ja) 2000-11-20 2009-01-07 ビオヴィトルム・アクチボラゲット（プブリクト） セロトニン５−ｈｔ２レセプターのアンタゴニストとしてのピペラジニルピラジン化合物
JPWO2002074746A1 (ja) * 2001-03-16 2004-07-08 山之内製薬株式会社 ベンゾアゼピン誘導体
BR0211140A (pt) * 2001-07-13 2005-10-25 Upjohn Co Compostos e composições de indóis de hexaidroazepina (4, 5-g) e indolinas como ligantes de receptores 5-ht
TWI312781B (en) 2002-04-25 2009-08-01 [1,4]diazepino[6,7,1-ij]quinoline derivatives as antipsychotic and antiobesity agents
TW200307682A (en) 2002-04-25 2003-12-16 Wyeth Corp 1,2,3,4,7,8-Hexahydro-6H-[1,4]diazepino[6,7,1-ij]quinoline derivatives as antipsychotic and antiobesity agents
TW200307540A (en) * 2002-04-25 2003-12-16 Wyeth Corp [1, 4]Diazocino[7, 8, 1-hi] indole derivatives as antipsychotic and antiobesity agents
BR0311970A (pt) 2002-06-19 2005-03-29 Biovitrum Ab Novos compostos, seu uso e preparação
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