KR20070086814A - 축합 인돌린 유도체들과 5ｈｔ, 특히 5ｈｔ2ｃ, 수용체리간드로서 이들의 사용 - Google Patents

축합 인돌린 유도체들과 5ｈｔ, 특히 5ｈｔ2ｃ, 수용체리간드로서 이들의 사용 Download PDF

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KR20070086814A
KR20070086814A KR1020077014953A KR20077014953A KR20070086814A KR 20070086814 A KR20070086814 A KR 20070086814A KR 1020077014953 A KR1020077014953 A KR 1020077014953A KR 20077014953 A KR20077014953 A KR 20077014953A KR 20070086814 A KR20070086814 A KR 20070086814A
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indole
mixture
alkyl
propylamine
saturated
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조나단 리차드 안토니 로페이
제임스 에드워드 폴 데이비드슨
하워드 랑햄 만셀
리차드 존 햄린
데이비드 레지날드 아담스
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베르날리스 리서치 리미티드
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Publication of KR20070086814A publication Critical patent/KR20070086814A/ko
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
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    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
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    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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    • C07D209/80—[b, c]- or [b, d]-condensed
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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KR1020077014953A 1999-08-11 2000-08-04 축합 인돌린 유도체들과 5ｈｔ, 특히 5ｈｔ2ｃ, 수용체리간드로서 이들의 사용 Ceased KR20070086814A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9918965.6 1999-08-11
GBGB9918965.6A GB9918965D0 (en) 1999-08-11 1999-08-11 Chemical compounds xxi

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KR1020027001107A Division KR20020015077A (ko) 1999-08-11 2000-08-04 축합 인돌린 유도체들과 5ｈｔ, 특히 5ｈｔ2ｃ, 수용체리간드로서 이들의 사용

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KR20070086814A true KR20070086814A (ko) 2007-08-27

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KR1020077014953A Ceased KR20070086814A (ko) 1999-08-11 2000-08-04 축합 인돌린 유도체들과 5ｈｔ, 특히 5ｈｔ2ｃ, 수용체리간드로서 이들의 사용
KR1020027001107A Abandoned KR20020015077A (ko) 1999-08-11 2000-08-04 축합 인돌린 유도체들과 5ｈｔ, 특히 5ｈｔ2ｃ, 수용체리간드로서 이들의 사용

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US (10) US6962939B1 (enExample)
EP (1) EP1202964B1 (enExample)
JP (1) JP2003507366A (enExample)
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CN (1) CN1167681C (enExample)
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GB9918965D0 (en) * 1999-08-11 1999-10-13 Cerebrus Ltd Chemical compounds xxi
SE0004245D0 (sv) 2000-11-20 2000-11-20 Pharmacia Ab Novel compounds and their use
JP4204315B2 (ja) 2000-11-20 2009-01-07 ビオヴィトルム・アクチボラゲット（プブリクト） セロトニン５−ｈｔ２レセプターのアンタゴニストとしてのピペラジニルピラジン化合物
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US6962939B1 (en) 2005-11-08
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US20070099981A1 (en) 2007-05-03
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US20070105889A1 (en) 2007-05-10
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US7323487B2 (en) 2008-01-29
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