CN1163607C - 具有氨肽酶活性的多肽及其编码核酸 - Google Patents

具有氨肽酶活性的多肽及其编码核酸 Download PDF

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Publication number
CN1163607C
CN1163607C CNB988051745A CN98805174A CN1163607C CN 1163607 C CN1163607 C CN 1163607C CN B988051745 A CNB988051745 A CN B988051745A CN 98805174 A CN98805174 A CN 98805174A CN 1163607 C CN1163607 C CN 1163607C
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CN
China
Prior art keywords
polypeptide
sequence
cell
gene
ala
Prior art date
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Expired - Fee Related
Application number
CNB988051745A
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English (en)
Chinese (zh)
Other versions
CN1276012A (zh
Inventor
A�������ֿ�
A·布林克沃斯凯
K·布朗
E·格莱特里
T·博恩
�Ƹ���
L·V·科弗德
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Novozymes AS
Original Assignee
Novozymes AS
Novozymes Biotech Inc
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Publication date
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Publication of CN1276012A publication Critical patent/CN1276012A/zh
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Publication of CN1163607C publication Critical patent/CN1163607C/zh
Anticipated expiration legal-status Critical
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A21—BAKING; EDIBLE DOUGHS
    • A21D—TREATMENT OF FLOUR OR DOUGH FOR BAKING, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS
    • A21D2/00—Treatment of flour or dough by adding materials thereto before or during baking
    • A21D2/08—Treatment of flour or dough by adding materials thereto before or during baking by adding organic substances
    • A21D2/24—Organic nitrogen compounds
    • A21D2/26—Proteins
    • A21D2/267—Microbial proteins
    • A—HUMAN NECESSITIES
    • A21—BAKING; EDIBLE DOUGHS
    • A21D—TREATMENT OF FLOUR OR DOUGH FOR BAKING, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS
    • A21D2/00—Treatment of flour or dough by adding materials thereto before or during baking
    • A21D2/08—Treatment of flour or dough by adding materials thereto before or during baking by adding organic substances
    • A21D2/24—Organic nitrogen compounds
    • A21D2/26—Proteins
    • A21D2/268—Hydrolysates from proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00—Working-up of proteins for foodstuffs
    • A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
    • A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
    • A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/20—Synthetic spices, flavouring agents or condiments
    • A23L27/21—Synthetic spices, flavouring agents or condiments containing amino acids

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Bakery Products And Manufacturing Methods Therefor (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CNB988051745A 1997-05-16 1998-05-15 具有氨肽酶活性的多肽及其编码核酸 Expired - Fee Related CN1163607C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US85788697A 1997-05-16 1997-05-16
US08/857,886 1997-05-16
US6289397P 1997-10-20 1997-10-20
US60/062,893 1997-10-20

Publications (2)

Publication Number Publication Date
CN1276012A CN1276012A (zh) 2000-12-06
CN1163607C true CN1163607C (zh) 2004-08-25

Family

ID=26742835

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB988051745A Expired - Fee Related CN1163607C (zh) 1997-05-16 1998-05-15 具有氨肽酶活性的多肽及其编码核酸

Country Status (10)

Country Link
US (2) US6800467B1 (https=)
EP (1) EP0981631B1 (https=)
JP (1) JP4128632B2 (https=)
CN (1) CN1163607C (https=)
AT (1) ATE358725T1 (https=)
AU (1) AU7489098A (https=)
DE (1) DE69837475T2 (https=)
DK (1) DK0981631T3 (https=)
ES (1) ES2285771T3 (https=)
WO (1) WO1998051804A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103361287A (zh) * 2013-06-25 2013-10-23 江南大学 一株耐热氨肽酶的产生菌及该酶的纯化方法

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6800467B1 (en) * 1997-05-16 2004-10-05 Novozymes Biotech, Inc. Polypeptides having aminopeptidase activity and nucleic acids encoding same
JP3727780B2 (ja) * 1998-06-12 2005-12-14 キッコーマン株式会社 ロイシンアミノペプチダーゼ遺伝子、組み換え体ｄｎａ及びロイシンアミノペプチダーゼの製造法
US6303359B1 (en) * 1999-03-15 2001-10-16 Ajinomoto Co., Inc. DNA molecule encoding new aminopeptidase, and method of producing the aminopeptidase
ES2316469T3 (es) * 2000-08-23 2009-04-16 Dsm Ip Assets B.V. Amenopeptidasa.
WO2002068623A2 (en) * 2001-02-23 2002-09-06 Dsm Ip Assets B.V. Genes encoding proteolytic enzymes from aspargilli
WO2004104203A1 (ja) 2003-05-21 2004-12-02 Asahi Kasei Pharma Corporation ヘモグロビンA1c測定法およびそれに用いる酵素とその製造法
JP4529183B2 (ja) * 2003-05-27 2010-08-25 味の素株式会社 飲食品の呈味および／または風味の改善方法
US20070190226A1 (en) * 2003-06-10 2007-08-16 Kyowa Hakko Food Specialites Co., Ltd. Seasoning
JP2008526261A (ja) * 2005-01-17 2008-07-24 ノボザイムス ノース アメリカ，インコーポレイティド 香味増強方法
JP4862759B2 (ja) 2006-06-30 2012-01-25 味の素株式会社 澱粉含有食品の製造方法及び澱粉含有食品改質用の酵素製剤
US9493759B2 (en) 2008-12-12 2016-11-15 Novozymes, Inc. Polypeptides having aspartic endopeptidase activity and polynucleotides encoding same
CN102492646A (zh) * 2011-11-22 2012-06-13 江南大学 一种高产氨肽酶的重组大肠杆菌及其构建方法
WO2013092731A1 (en) * 2011-12-21 2013-06-27 Dsm Ip Assets B.V. Method for making a dough with a glutamyl endopeptidase
KR101421534B1 (ko) 2012-05-04 2014-07-24 전북대학교산학협력단 항균 활성 및 항암 활성이 강화된 리소좀의 제조방법
EP3314004A1 (en) * 2015-06-26 2018-05-02 DuPont Nutrition Biosciences ApS Aminopeptidases for protein hydrolyzates
CN104975060A (zh) * 2015-07-28 2015-10-14 中国科学院海洋研究所 一种假交替单胞菌重组氨肽酶的应用
WO2017089408A1 (en) * 2015-11-24 2017-06-01 Novozymes A/S Method for producing bile acids
EP4317428A4 (en) * 2021-03-31 2025-04-23 Nagase Viita Co., Ltd. Enzyme composition for food

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3905194A1 (de) 1989-02-21 1990-08-23 Roehm Gmbh Verfahren zur herstellung von protein-hydrolysaten mit niedrigem gehalt an bitterstoffen
NL194258C (nl) * 1989-09-01 2001-11-05 Protein Technologies Internat Werkwijze voor het behandelen van een eiwithoudend materiaal.
JPH0795951B2 (ja) * 1989-10-27 1995-10-18 わかもと製薬株式会社 広域ｐＨ作用を有する新規なロイシンアミノペプチダーゼ
CN1057127C (zh) * 1993-04-23 2000-10-04 北京大学 固定化复合外肽酶蛋白质全水解及脱苦方法
WO1996014404A1 (en) * 1994-11-08 1996-05-17 Novo Nordisk A/S Tripeptidyl aminopeptidase
AU4939396A (en) 1995-03-16 1996-10-02 Novo Nordisk A/S An enzyme with aminopeptidase activity
DE19526485A1 (de) * 1995-07-20 1997-01-23 Roehm Gmbh Rekombinant hergestellte Leucinaminopeptidase aus Aspergillus sojae
CN1099839C (zh) 1996-05-20 2003-01-29 诺沃奇梅兹有限公司 一种获得蛋白质水解物的方法
US6800467B1 (en) * 1997-05-16 2004-10-05 Novozymes Biotech, Inc. Polypeptides having aminopeptidase activity and nucleic acids encoding same

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103361287A (zh) * 2013-06-25 2013-10-23 江南大学 一株耐热氨肽酶的产生菌及该酶的纯化方法
CN103361287B (zh) * 2013-06-25 2014-07-23 江南大学 一株耐热氨肽酶的产生菌及该酶的纯化方法

Also Published As

Publication number Publication date
ES2285771T3 (es) 2007-11-16
DE69837475D1 (de) 2007-05-16
ATE358725T1 (de) 2007-04-15
EP0981631B1 (en) 2007-04-04
US7279308B2 (en) 2007-10-09
US6800467B1 (en) 2004-10-05
DK0981631T3 (da) 2007-08-06
DE69837475T2 (de) 2007-12-13
JP4128632B2 (ja) 2008-07-30
CN1276012A (zh) 2000-12-06
JP2002514920A (ja) 2002-05-21
AU7489098A (en) 1998-12-08
US20050118610A1 (en) 2005-06-02
EP0981631A1 (en) 2000-03-01
WO1998051804A1 (en) 1998-11-19

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Address after: American California

Applicant after: NOVOZYMES BIOTECH, Inc.

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Free format text: CORRECT: APPLICANT; FROM: NOVO NORDISK BIOTECH, INC. TO: NOVO NORDISK BIOTECH INC.

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