CN113476395A - Moisturizing and skin-activating cosmetic cream and preparation method thereof - Google Patents
Moisturizing and skin-activating cosmetic cream and preparation method thereof Download PDFInfo
- Publication number
- CN113476395A CN113476395A CN202110830614.2A CN202110830614A CN113476395A CN 113476395 A CN113476395 A CN 113476395A CN 202110830614 A CN202110830614 A CN 202110830614A CN 113476395 A CN113476395 A CN 113476395A
- Authority
- CN
- China
- Prior art keywords
- skin
- cosmetic cream
- sodium
- compound
- cosmetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008278 cosmetic cream Substances 0.000 title claims abstract description 20
- 238000002360 preparation method Methods 0.000 title claims abstract description 7
- 230000003020 moisturizing effect Effects 0.000 title abstract description 12
- 239000000284 extract Substances 0.000 claims abstract description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 10
- 235000004727 Opuntia ficus indica Nutrition 0.000 claims abstract description 6
- 240000009297 Opuntia ficus-indica Species 0.000 claims abstract description 6
- 239000002260 anti-inflammatory agent Substances 0.000 claims abstract description 5
- 229940121363 anti-inflammatory agent Drugs 0.000 claims abstract description 5
- 239000003974 emollient agent Substances 0.000 claims abstract description 5
- 239000003906 humectant Substances 0.000 claims abstract description 5
- 239000000043 antiallergic agent Substances 0.000 claims abstract description 4
- 239000008271 cosmetic emulsion Substances 0.000 claims abstract description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 16
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 claims description 16
- -1 glycerol tri (ethyl hexanoate) ester Chemical class 0.000 claims description 13
- XDOFQFKRPWOURC-UHFFFAOYSA-N 16-methylheptadecanoic acid Chemical compound CC(C)CCCCCCCCCCCCCCC(O)=O XDOFQFKRPWOURC-UHFFFAOYSA-N 0.000 claims description 12
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 claims description 12
- 229920006037 cross link polymer Polymers 0.000 claims description 12
- 239000004205 dimethyl polysiloxane Substances 0.000 claims description 12
- 235000013870 dimethyl polysiloxane Nutrition 0.000 claims description 12
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims description 12
- 238000003756 stirring Methods 0.000 claims description 10
- 235000013336 milk Nutrition 0.000 claims description 9
- 210000004080 milk Anatomy 0.000 claims description 9
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims description 8
- 150000001875 compounds Chemical class 0.000 claims description 8
- 238000000855 fermentation Methods 0.000 claims description 8
- 230000004151 fermentation Effects 0.000 claims description 8
- 239000008267 milk Substances 0.000 claims description 8
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 claims description 8
- 229940032094 squalane Drugs 0.000 claims description 8
- 230000001804 emulsifying effect Effects 0.000 claims description 7
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 claims description 7
- 239000000047 product Substances 0.000 claims description 7
- WTVHAMTYZJGJLJ-UHFFFAOYSA-N (+)-(4S,8R)-8-epi-beta-bisabolol Natural products CC(C)=CCCC(C)C1(O)CCC(C)=CC1 WTVHAMTYZJGJLJ-UHFFFAOYSA-N 0.000 claims description 6
- FYGDTMLNYKFZSV-URKRLVJHSA-N (2s,3r,4s,5s,6r)-2-[(2r,4r,5r,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5r,6s)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical group O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1[C@@H](CO)O[C@@H](OC2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-URKRLVJHSA-N 0.000 claims description 6
- KZRXPHCVIMWWDS-AWEZNQCLSA-N (4S)-4-amino-5-dodecanoyloxy-5-oxopentanoic acid Chemical compound CCCCCCCCCCCC(=O)OC(=O)[C@@H](N)CCC(O)=O KZRXPHCVIMWWDS-AWEZNQCLSA-N 0.000 claims description 6
- PQUXFUBNSYCQAL-UHFFFAOYSA-N 1-(2,3-difluorophenyl)ethanone Chemical compound CC(=O)C1=CC=CC(F)=C1F PQUXFUBNSYCQAL-UHFFFAOYSA-N 0.000 claims description 6
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims description 6
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 6
- LEACJMVNYZDSKR-UHFFFAOYSA-N 2-octyldodecan-1-ol Chemical compound CCCCCCCCCCC(CO)CCCCCCCC LEACJMVNYZDSKR-UHFFFAOYSA-N 0.000 claims description 6
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims description 6
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims description 6
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 claims description 6
- 229920002498 Beta-glucan Polymers 0.000 claims description 6
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 claims description 6
- 235000010254 Jasminum officinale Nutrition 0.000 claims description 6
- 240000005385 Jasminum sambac Species 0.000 claims description 6
- 241000186660 Lactobacillus Species 0.000 claims description 6
- 244000178870 Lavandula angustifolia Species 0.000 claims description 6
- 235000010663 Lavandula angustifolia Nutrition 0.000 claims description 6
- 239000004264 Petrolatum Substances 0.000 claims description 6
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims description 6
- 229920002385 Sodium hyaluronate Polymers 0.000 claims description 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 6
- 229940048053 acrylate Drugs 0.000 claims description 6
- 229960000458 allantoin Drugs 0.000 claims description 6
- RGZSQWQPBWRIAQ-LSDHHAIUSA-N alpha-Bisabolol Natural products CC(C)=CCC[C@@](C)(O)[C@@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-LSDHHAIUSA-N 0.000 claims description 6
- BTFJIXJJCSYFAL-UHFFFAOYSA-N arachidyl alcohol Natural products CCCCCCCCCCCCCCCCCCCCO BTFJIXJJCSYFAL-UHFFFAOYSA-N 0.000 claims description 6
- 229940036350 bisabolol Drugs 0.000 claims description 6
- HHGZABIIYIWLGA-UHFFFAOYSA-N bisabolol Natural products CC1CCC(C(C)(O)CCC=C(C)C)CC1 HHGZABIIYIWLGA-UHFFFAOYSA-N 0.000 claims description 6
- 239000003795 chemical substances by application Substances 0.000 claims description 6
- 229920001577 copolymer Polymers 0.000 claims description 6
- 229940008099 dimethicone Drugs 0.000 claims description 6
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 claims description 6
- 239000000706 filtrate Substances 0.000 claims description 6
- 235000011187 glycerol Nutrition 0.000 claims description 6
- 229940039696 lactobacillus Drugs 0.000 claims description 6
- 229940071085 lauroyl glutamate Drugs 0.000 claims description 6
- 239000001102 lavandula vera Substances 0.000 claims description 6
- 235000018219 lavender Nutrition 0.000 claims description 6
- 229940101267 panthenol Drugs 0.000 claims description 6
- 235000020957 pantothenol Nutrition 0.000 claims description 6
- 239000011619 pantothenol Substances 0.000 claims description 6
- 229940066842 petrolatum Drugs 0.000 claims description 6
- 235000019271 petrolatum Nutrition 0.000 claims description 6
- 229960005323 phenoxyethanol Drugs 0.000 claims description 6
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 claims description 6
- 229940047670 sodium acrylate Drugs 0.000 claims description 6
- 229940010747 sodium hyaluronate Drugs 0.000 claims description 6
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 claims description 6
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims description 6
- GYDJEQRTZSCIOI-LJGSYFOKSA-N tranexamic acid Chemical compound NC[C@H]1CC[C@H](C(O)=O)CC1 GYDJEQRTZSCIOI-LJGSYFOKSA-N 0.000 claims description 6
- 229960000401 tranexamic acid Drugs 0.000 claims description 6
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims description 6
- 229920002554 vinyl polymer Polymers 0.000 claims description 6
- RGZSQWQPBWRIAQ-CABCVRRESA-N (-)-alpha-Bisabolol Chemical compound CC(C)=CCC[C@](C)(O)[C@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-CABCVRRESA-N 0.000 claims description 5
- SVTBMSDMJJWYQN-UHFFFAOYSA-N 2-methylpentane-2,4-diol Chemical compound CC(O)CC(C)(C)O SVTBMSDMJJWYQN-UHFFFAOYSA-N 0.000 claims description 4
- 229940126062 Compound A Drugs 0.000 claims description 4
- NLDMNSXOCDLTTB-UHFFFAOYSA-N Heterophylliin A Natural products O1C2COC(=O)C3=CC(O)=C(O)C(O)=C3C3=C(O)C(O)=C(O)C=C3C(=O)OC2C(OC(=O)C=2C=C(O)C(O)=C(O)C=2)C(O)C1OC(=O)C1=CC(O)=C(O)C(O)=C1 NLDMNSXOCDLTTB-UHFFFAOYSA-N 0.000 claims description 4
- 239000003995 emulsifying agent Substances 0.000 claims description 4
- 150000002148 esters Chemical class 0.000 claims description 4
- 238000002156 mixing Methods 0.000 claims description 4
- 229940023750 peg-60 glyceryl isostearate Drugs 0.000 claims description 4
- 239000003755 preservative agent Substances 0.000 claims description 4
- LVTJOONKWUXEFR-FZRMHRINSA-N protoneodioscin Natural products O(C[C@@H](CC[C@]1(O)[C@H](C)[C@@H]2[C@]3(C)[C@H]([C@H]4[C@@H]([C@]5(C)C(=CC4)C[C@@H](O[C@@H]4[C@H](O[C@H]6[C@@H](O)[C@@H](O)[C@@H](O)[C@H](C)O6)[C@@H](O)[C@H](O[C@H]6[C@@H](O)[C@@H](O)[C@@H](O)[C@H](C)O6)[C@H](CO)O4)CC5)CC3)C[C@@H]2O1)C)[C@H]1[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1 LVTJOONKWUXEFR-FZRMHRINSA-N 0.000 claims description 4
- 239000002562 thickening agent Substances 0.000 claims description 4
- QFOHBWFCKVYLES-UHFFFAOYSA-N Butylparaben Chemical compound CCCCOC(=O)C1=CC=C(O)C=C1 QFOHBWFCKVYLES-UHFFFAOYSA-N 0.000 claims description 3
- 235000010469 Glycine max Nutrition 0.000 claims description 3
- 244000068988 Glycine max Species 0.000 claims description 3
- 150000001720 carbohydrates Chemical class 0.000 claims description 3
- 239000003205 fragrance Substances 0.000 claims description 3
- 238000010438 heat treatment Methods 0.000 claims description 3
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 claims description 3
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 claims description 3
- 229960002216 methylparaben Drugs 0.000 claims description 3
- 230000002335 preservative effect Effects 0.000 claims description 3
- QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 claims description 3
- 235000013322 soy milk Nutrition 0.000 claims description 3
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims description 2
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 claims description 2
- DGSZGZSCHSQXFV-UHFFFAOYSA-N 2,3-bis(2-ethylhexanoyloxy)propyl 2-ethylhexanoate Chemical compound CCCCC(CC)C(=O)OCC(OC(=O)C(CC)CCCC)COC(=O)C(CC)CCCC DGSZGZSCHSQXFV-UHFFFAOYSA-N 0.000 claims description 2
- NLMKTBGFQGKQEV-UHFFFAOYSA-N 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hexadecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol Chemical compound CCCCCCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO NLMKTBGFQGKQEV-UHFFFAOYSA-N 0.000 claims description 2
- UIVPNOBLHXUKDX-UHFFFAOYSA-N 3,5,5-trimethylhexyl 3,5,5-trimethylhexanoate Chemical compound CC(C)(C)CC(C)CCOC(=O)CC(C)CC(C)(C)C UIVPNOBLHXUKDX-UHFFFAOYSA-N 0.000 claims description 2
- 229940099451 3-iodo-2-propynylbutylcarbamate Drugs 0.000 claims description 2
- WYVVKGNFXHOCQV-UHFFFAOYSA-N 3-iodoprop-2-yn-1-yl butylcarbamate Chemical compound CCCCNC(=O)OCC#CI WYVVKGNFXHOCQV-UHFFFAOYSA-N 0.000 claims description 2
- 229940100484 5-chloro-2-methyl-4-isothiazolin-3-one Drugs 0.000 claims description 2
- 239000004475 Arginine Substances 0.000 claims description 2
- 241000219357 Cactaceae Species 0.000 claims description 2
- BIVBRWYINDPWKA-VLQRKCJKSA-L Glycyrrhizinate dipotassium Chemical compound [K+].[K+].O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@H]1CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@](C)(CC[C@@]5(CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C)C)C(O)=O)C([O-])=O)[C@@H]1O[C@H](C([O-])=O)[C@@H](O)[C@H](O)[C@H]1O BIVBRWYINDPWKA-VLQRKCJKSA-L 0.000 claims description 2
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 claims description 2
- SSISHJJTAXXQAX-ZETCQYMHSA-N L-ergothioneine Chemical compound C[N+](C)(C)[C@H](C([O-])=O)CC1=CNC(=S)N1 SSISHJJTAXXQAX-ZETCQYMHSA-N 0.000 claims description 2
- 235000019082 Osmanthus Nutrition 0.000 claims description 2
- 241000333181 Osmanthus Species 0.000 claims description 2
- 229920001213 Polysorbate 20 Polymers 0.000 claims description 2
- 240000000851 Vaccinium corymbosum Species 0.000 claims description 2
- 235000003095 Vaccinium corymbosum Nutrition 0.000 claims description 2
- 235000017537 Vaccinium myrtillus Nutrition 0.000 claims description 2
- CBTVGIZVANVGBH-UHFFFAOYSA-N aminomethyl propanol Chemical compound CC(C)(N)CO CBTVGIZVANVGBH-UHFFFAOYSA-N 0.000 claims description 2
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims description 2
- 235000021014 blueberries Nutrition 0.000 claims description 2
- 229940041514 candida albicans extract Drugs 0.000 claims description 2
- DHNRXBZYEKSXIM-UHFFFAOYSA-N chloromethylisothiazolinone Chemical compound CN1SC(Cl)=CC1=O DHNRXBZYEKSXIM-UHFFFAOYSA-N 0.000 claims description 2
- 230000003750 conditioning effect Effects 0.000 claims description 2
- 229940101029 dipotassium glycyrrhizinate Drugs 0.000 claims description 2
- 229940113120 dipropylene glycol Drugs 0.000 claims description 2
- 229940093497 ergothioneine Drugs 0.000 claims description 2
- 229960005150 glycerol Drugs 0.000 claims description 2
- 229940075529 glyceryl stearate Drugs 0.000 claims description 2
- 229940051250 hexylene glycol Drugs 0.000 claims description 2
- 229920013818 hydroxypropyl guar gum Polymers 0.000 claims description 2
- ZCTXEAQXZGPWFG-UHFFFAOYSA-N imidurea Chemical compound O=C1NC(=O)N(CO)C1NC(=O)NCNC(=O)NC1C(=O)NC(=O)N1CO ZCTXEAQXZGPWFG-UHFFFAOYSA-N 0.000 claims description 2
- 229940100554 isononyl isononanoate Drugs 0.000 claims description 2
- XUGNVMKQXJXZCD-UHFFFAOYSA-N isopropyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC(C)C XUGNVMKQXJXZCD-UHFFFAOYSA-N 0.000 claims description 2
- 229940075495 isopropyl palmitate Drugs 0.000 claims description 2
- ASKIVFGGGGIGKH-UHFFFAOYSA-N isostearic acid monoglyceride Natural products CC(C)CCCCCCCCCCCCCCC(=O)OCC(O)CO ASKIVFGGGGIGKH-UHFFFAOYSA-N 0.000 claims description 2
- RGUVUPQQFXCJFC-UHFFFAOYSA-N n-hydroxyoctanamide Chemical compound CCCCCCCC(=O)NO RGUVUPQQFXCJFC-UHFFFAOYSA-N 0.000 claims description 2
- 230000003472 neutralizing effect Effects 0.000 claims description 2
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 claims description 2
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 claims description 2
- 229940068977 polysorbate 20 Drugs 0.000 claims description 2
- 229960003415 propylparaben Drugs 0.000 claims description 2
- 229940109850 royal jelly Drugs 0.000 claims description 2
- CRPCXAMJWCDHFM-UHFFFAOYSA-M sodium;5-oxopyrrolidine-2-carboxylate Chemical compound [Na+].[O-]C(=O)C1CCC(=O)N1 CRPCXAMJWCDHFM-UHFFFAOYSA-M 0.000 claims description 2
- 239000000230 xanthan gum Substances 0.000 claims description 2
- 229920001285 xanthan gum Polymers 0.000 claims description 2
- 235000010493 xanthan gum Nutrition 0.000 claims description 2
- 229940082509 xanthan gum Drugs 0.000 claims description 2
- 239000012138 yeast extract Substances 0.000 claims description 2
- WHBKVWBGTBULQY-UHFFFAOYSA-N 2-propylheptyl octanoate Chemical compound CCCCCCCC(=O)OCC(CCC)CCCCC WHBKVWBGTBULQY-UHFFFAOYSA-N 0.000 claims 1
- 241000207929 Scutellaria Species 0.000 claims 1
- 235000010418 carrageenan Nutrition 0.000 claims 1
- 229940074992 chondrus crispus extract Drugs 0.000 claims 1
- 239000001649 glycyrrhiza glabra l. absolute Substances 0.000 claims 1
- 229940051810 licorice root extract Drugs 0.000 claims 1
- 235000020725 licorice root extract Nutrition 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000002304 perfume Substances 0.000 claims 1
- 230000004060 metabolic process Effects 0.000 abstract description 4
- 230000037394 skin elasticity Effects 0.000 abstract description 2
- 238000012360 testing method Methods 0.000 description 9
- 230000000694 effects Effects 0.000 description 7
- 230000000052 comparative effect Effects 0.000 description 5
- 239000002537 cosmetic Substances 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 238000012935 Averaging Methods 0.000 description 2
- SHZIWNPUGXLXDT-UHFFFAOYSA-N ethyl hexanoate Chemical compound CCCCCC(=O)OCC SHZIWNPUGXLXDT-UHFFFAOYSA-N 0.000 description 2
- 230000002045 lasting effect Effects 0.000 description 2
- 230000037067 skin hydration Effects 0.000 description 2
- 208000002874 Acne Vulgaris Diseases 0.000 description 1
- 241000132012 Atractylodes Species 0.000 description 1
- NMAQSOQOKDHXGW-NOVBDOAMSA-N C(CCCCCCCCCCCCCCCCC)(=O)O.CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.C(CCCCCCCCCCCCCCCCC)(=O)O.C(CCCCCCCCCCCCCCCCC)(=O)O.CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO Chemical compound C(CCCCCCCCCCCCCCCCC)(=O)O.CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.C(CCCCCCCCCCCCCCCCC)(=O)O.C(CCCCCCCCCCCCCCCCC)(=O)O.CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO NMAQSOQOKDHXGW-NOVBDOAMSA-N 0.000 description 1
- 241000206575 Chondrus crispus Species 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 244000044822 Simmondsia californica Species 0.000 description 1
- 235000004433 Simmondsia californica Nutrition 0.000 description 1
- 206010000496 acne Diseases 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 238000003915 air pollution Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 125000002138 bisabolol group Chemical group 0.000 description 1
- 229940067596 butylparaben Drugs 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 238000012512 characterization method Methods 0.000 description 1
- OQBIVESRYIWBPL-UHFFFAOYSA-N decan-4-yl octanoate Chemical compound CCCCCCCC(=O)OC(CCC)CCCCCC OQBIVESRYIWBPL-UHFFFAOYSA-N 0.000 description 1
- 210000001339 epidermal cell Anatomy 0.000 description 1
- 125000005456 glyceride group Chemical group 0.000 description 1
- 230000000887 hydrating effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 235000010232 propyl p-hydroxybenzoate Nutrition 0.000 description 1
- 239000004405 propyl p-hydroxybenzoate Substances 0.000 description 1
- 230000009759 skin aging Effects 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/85—Polyesters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/895—Polysiloxanes containing silicon bound to unsaturated aliphatic groups, e.g. vinyl dimethicone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Dermatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a moisturizing and skin-activating cosmetic cream and a preparation method thereof, wherein the cosmetic cream comprises the following components in percentage by mass: 6-18% of an emollient, 0.05-1% of an anti-inflammatory agent, 0.05-1% of a skin conditioner, 4-12% of a humectant, 0.05-0.8% of an anti-allergy agent, 0.1-1.5% of a stem extract of opuntia ficus-indica and 0.05-1% of a skin conditioner. The moisturizing and skin-activating cosmetic emulsion provided by the invention can effectively promote skin metabolism, improve skin elasticity, replenish water, moisturize, nourish and activate skin, improve the self resistance and water locking capacity of skin, improve fine lines and looseness caused by dryness and water shortage, and reestablish water-oil balance of skin.
Description
Technical Field
The invention belongs to the technical field of cosmetics, and particularly relates to a moisturizing and skin-activating cosmetic cream and a preparation method thereof.
Background
With the coming of summer days with inflammation, the use of air conditioners is more and more frequent, and air pollution and the like cause the problems of skin aging, metabolism slowing and the like to be gradually increased, so that the skin moisture loss is serious.
The water in the skin mainly has the effects of controlling epidermal cells to delay the mature period, reducing metabolism, improving the activity and the plumpness of mature cells and avoiding aging and wrinkle generation. And the water retention can also improve the resistance degree to external stimulation, reduce the appearance of acne and the like, and make the skin moist, soft and elastic. However, the existing skin care products have poor and satisfactory efficacy and are difficult to realize the moisture supplement requirement required by the skin. Therefore, it is eagerly to develop a multi-moisturizing, hydrating and skin-activating cosmetic.
Disclosure of Invention
The first purpose of the invention is to provide the moisturizing and skin-activating cosmetic cream.
The second purpose of the invention is to provide a preparation method of the cosmetic cream.
The technical scheme adopted by the invention is as follows:
in a first aspect of the invention, a cosmetic cream is provided, which comprises the following components by mass percent: 6-18% of an emollient, 0.05-1% of an anti-inflammatory agent, 0.05-1% of a skin conditioner, 4-12% of a humectant, 0.05-0.8% of an anti-allergy agent, 0.1-1.5% of a stem extract of opuntia ficus-indica and 0.05-1% of a skin conditioner.
In some embodiments of the invention, the emollient is at least one of isopropyl palmitate, squalane, isononyl isononanoate, glycerol tri (ethyl hexanoate), petrolatum, propyl heptyl octanoate, dimethicone/vinyl dimethicone crosspolymer, and squalane.
In some embodiments of the invention, the anti-inflammatory agent is at least one of dipotassium glycyrrhizinate, ergothioneine, extract of the root of white atractylodes rhizome and extract of Chondrus CRISPUS, and allantoin.
In some embodiments of the invention, the skin conditioner is at least one of a royal jelly fermentation broth, a hydrolyzed yeast extract, and tranexamic acid.
In some embodiments of the invention, the humectant is at least one of sodium PCA, hexylene glycol, butylene glycol, luba gum, dipropylene glycol, glycerin, panthenol, lactobacillus/soy milk fermentation product filtrate, bioglycan-1, and sodium hyaluronate.
In some embodiments of the invention, the anti-sensitivity agent is bisabolol.
In some embodiments of the invention, the skin conditioning agent is beta-glucan.
In some embodiments of the invention, the cosmetic milk further comprises an emulsifier, a fragrance, a preservative, a thickener, a neutralizer.
In some embodiments of the invention, the emulsifier is at least one of polysorbate-20, methylglucamine sesquistearate, ceteth-25, glyceryl stearate, PEG-60 glyceryl isostearate, phytosterol/octyldodecanol lauroyl glutamate, isostearic acid, and sodium acrylate/sodium acryloyldimethyl taurate copolymer.
In some embodiments of the invention, the fragrance is at least one of osmanthus essence, blueberry essence, lavender essence, and jasmine essence.
In some embodiments of the invention, the preservative is at least one of phenoxyethanol, methylparaben, imidazolidinyl urea, caprylhydroxamic acid, propylparaben, butylparaben, iodopropynyl butylcarbamate, methylparaben, and methylchloroisothiazolinone.
In some embodiments of the invention, the thickener is at least one of xanthan gum, hydroxypropyl guar gum, acrylic acid/C10-30 alkanol acrylate crosspolymer, AVC, and sodium polyacrylate.
In some embodiments of the invention, the neutralizing agent is at least one of triethanolamine, sodium hydroxide, potassium hydroxide, triethanolamine, aminomethyl propanol, and arginine.
In a second aspect of the present invention, there is provided a process for preparing the cosmetic cream according to the first aspect of the present invention, comprising the steps of:
s1: heating and dissolving glycerol tri (ethyl hexanoate) ester, petrolatum, PEG-60 glycerol isostearate and caprylic propyl heptyl ester to obtain a compound A;
s2: mixing phytosterol/octyldodecanol lauroyl glutamate, polydimethylsiloxane/vinyl polydimethylsiloxane cross-linked polymer, isostearic acid, lavender essence, jasmine essence and squalane, and dissolving to obtain compound B;
s3: mixing water, phenoxyethanol, allantoin, tranexamic acid and panthenol, and dissolving to obtain compound C;
s4: c10-30 of acrylic acid (ester) is mixed and dissolved with alkanol acrylate cross-linked polymer, AVC, sodium polyacrylate, luba gum, dipropylene glycol and glycerol to obtain a compound D;
s5: pouring the compound C and the compound D into an emulsifying pot, adding the compound A and the compound B after uniformly stirring, adding triethanolamine after uniformly homogenizing and emulsifying, adding bisabolol, sodium acrylate/sodium acryloyldimethyl taurate copolymer, lactobacillus/soybean milk fermentation product filtrate, biological carbohydrate gum-1, cactus stem extract, beta-glucan and sodium hyaluronate after uniformly stirring.
In some embodiments of the invention, the temperature in step S1 is ≦ 60 ℃.
The invention has the beneficial effects that:
the moisturizing and skin-activating cosmetic emulsion provided by the invention can effectively promote skin metabolism, improve skin elasticity, replenish water, moisturize, nourish and activate skin, improve the self resistance and water locking capacity of skin, improve fine lines and looseness caused by dryness and water shortage, and reestablish water-oil balance of skin.
Detailed Description
The concept and technical effects of the present invention will be clearly and completely described below in conjunction with the embodiments to fully understand the objects, features and effects of the present invention. It is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments, and those skilled in the art can obtain other embodiments without inventive effort based on the embodiments of the present invention, and all embodiments are within the protection scope of the present invention.
The starting materials used in the examples were prepared by conventional means or purchased from commercial sources, except as otherwise specified.
Glycerol tris (ethyl hexanoate) ester from CoGNIS, petrolatum from Tadalla, PEG-60 glyceryl isostearate from Shanghai, propylheptyl octanoate from CoGNIS, phytosterol/octyldodecanol lauroyl glutamate from AJINOMOTO Co., Inc., dimethicone/vinyl dimethicone crosspolymer from COGNIS, isostearic acid from Heda, lavender essence from Aiqile France, jasmine essence from Aiqile France, squalane from GNIS, phenoxyethanol from Inuchem, allantoin from DSM, tranexamic acid from Nibuland, panthenol from Roche, acrylic acid (GN ester)/C10-30 alkanol acrylate crosspolymer from Noveon, AVC from Too, sodium polyacrylate from CoGNIS, Phragamolan gum, dipropylene glycol from CoGNIS, Glycerol is available from COGNIS, triethanolamine from BP CHEMICALS, bisabolol from Ashland, sodium acrylate/sodium acryloyldimethyl taurate copolymer from SEPPIC, Lactobacillus/Soy milk fermentation product filtrate from Ashland, biogum-1 from miBelle AG, Opuntia FICUS-INDICA stem extract from miBell, beta-glucan from SK BIOLAND, sodium hyaluronate from Huaxi Furrida.
Examples and comparative examples
The formulas of the moisturizing and skin-activating cosmetic creams of examples 1 to 4 and comparative examples 1 to 4 are shown in table 1.
The preparation method of the moisturizing and skin-activating cosmetic cream of the embodiments 1 to 4 is as follows:
s1: heating and dissolving tri (ethyl hexanoate) glyceride, petrolatum, PEG-60 glyceryl isostearate, and caprylic propyl heptyl ester in a container (note temperature not higher than 60 deg.C);
s2: adding phytosterol/octyl dodecanol lauroyl glutamate, polydimethylsiloxane/vinyl polydimethylsiloxane cross-linked polymer, isostearic acid, lavender essence, jasmine essence and squalane into a container, and stirring for dissolving;
s3: adding water, phenoxyethanol, allantoin, tranexamic acid and panthenol into a container, stirring and dissolving;
s4: acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, AVC, sodium polyacrylate, jojoba gum, dipropylene glycol, and glycerol, adding into a container, stirring, and dissolving;
s5: pouring the materials in the steps 3 and 4 into an emulsifying pot, uniformly stirring, adding the materials in the steps 1 and 2 into the emulsifying pot, uniformly homogenizing and emulsifying, then adding triethanolamine, uniformly stirring, and adding the rest materials: bisabolol, sodium acrylate/sodium acryloyldimethyl taurate copolymer, lactobacillus/soybean milk fermentation product filtrate, biological carbohydrate gum-1, stem extract of Opuntia FICUS-INDICA (Opuntia FICUS-INDICA), beta-glucan and sodium hyaluronate, and uniformly stirring to obtain the material.
TABLE 1 formulas of moisturizing, skin-revitalizing cosmetic milks of examples 1 to 4 and comparative examples 1 to 4
Effect testing example
1) And (4) testing the moisturizing effect: selecting 80 volunteers aged 18-35 and having skin color L values close to each other, uniformly dividing into 8 groups, measuring the initial skin hydration degree (averaging) of each group of volunteers, respectively using the excellent live milk of examples 1-4 and comparative examples 1-4, lasting for 4 weeks once a day, testing the skin hydration degree (averaging) of each group of volunteers, and evaluating the moisturizing effect of the excellent live milk, wherein the test results are shown in Table 2.
Table 2 characterization test of properties
2) Testing the skin color effect:
selecting 24 volunteers aged 18-35 years and having skin complexion L values close to each other, uniformly dividing the selected volunteers into 8 groups, measuring the initial skin complexion L value of each group of volunteers (taking an average value), respectively using the excellent live milk of the embodiments 1-4 and the comparative examples 1-4, lasting for 4 weeks once a day, testing the skin complexion L value of each group of volunteers (taking an average value), and evaluating the skin activating effect of the excellent live milk, wherein the test results are shown in the following table 3.
Table 3 skin color effect test results
Note: the skin complexion L value was measured using a Colorimeter CL400, a skin color tester manufactured by Courage Khazaka, Germany.
The present invention is not limited to the above embodiments, and various changes can be made without departing from the spirit of the present invention within the knowledge of those skilled in the art. Furthermore, the embodiments of the present invention and the features of the embodiments may be combined with each other without conflict.
Claims (10)
1. A cosmetic cream comprises the following components in percentage by mass: 6-18% of an emollient, 0.05-1% of an anti-inflammatory agent, 0.05-1% of a skin conditioner, 4-12% of a humectant, 0.05-0.8% of an anti-allergy agent, 0.1-1.5% of a stem extract of opuntia ficus-indica and 0.05-1% of a skin conditioner.
2. The cosmetic emulsion of claim 1 wherein the emollient is at least one of isopropyl palmitate, squalane, isononyl isononanoate, glycerol tri (ethyl hexanoate), petrolatum, propyl heptyl caprylate, dimethicone/vinyl dimethicone crosspolymer, and squalane.
3. The cosmetic cream according to claim 1, wherein the anti-inflammatory agent is at least one of dipotassium glycyrrhizinate, ergothioneine, Atractylodis rhizoma root extract, Chondrus crispus extract and allantoin.
4. The cosmetic cream of claim 1, wherein the skin conditioner is at least one of a royal jelly fermentation broth, a hydrolyzed yeast extract, and tranexamic acid.
5. The cosmetic emulsion of claim 1 wherein the humectant is at least one of sodium PCA, hexylene glycol, butylene glycol, luba gum, dipropylene glycol, glycerin, panthenol, lactobacillus/soy milk fermentation product filtrate, bioglycan-1, and sodium hyaluronate.
6. The cosmetic cream of claim 1, wherein the anti-allergy agent is at least one of licorice root extract, scutellaria root extract and bisabolol.
7. The cosmetic cream of claim 1 wherein the skin conditioning agent is β -glucan.
8. The cosmetic cream according to claim 1, wherein the cosmetic cream further comprises emulsifiers, fragrances, preservatives, thickeners, neutralizers.
9. The cosmetic cream according to claim 8, wherein the emulsifier is at least one of polysorbate-20, methylglucoterate hemistearate, ceteth-25, glyceryl stearate, PEG-60 glyceryl isostearate, phytosterol/octyldodecanol lauroyl glutamate, isostearic acid, and sodium acrylate/sodium acryloyldimethyl taurate copolymer;
preferably, the perfume is at least one of osmanthus essence, blueberry essence, lavender essence and jasmine essence;
preferably, the preservative is at least one of phenoxyethanol, methyl hydroxybenzoate, imidazolidinyl urea, caprylhydroxamic acid, propyl hydroxybenzoate, butyl hydroxybenzoate, iodopropynyl butylcarbamate, methyl paraben and methylchloroisothiazolinone;
preferably, the thickener is at least one of xanthan gum, hydroxypropyl guar gum, acrylic acid/C10-30 alkanol acrylate crosspolymer, AVC and sodium polyacrylate;
preferably, the neutralizing agent is at least one of triethanolamine, sodium hydroxide, potassium hydroxide, triethanolamine, aminomethyl propanol, and arginine.
10. A process for the preparation of the cosmetic cream according to claim 9, comprising the steps of:
s1: heating and dissolving glycerol tri (ethyl hexanoate) ester, petrolatum, PEG-60 glycerol isostearate and caprylic propyl heptyl ester to obtain a compound A;
s2: mixing phytosterol/octyldodecanol lauroyl glutamate, polydimethylsiloxane/vinyl polydimethylsiloxane cross-linked polymer, isostearic acid, lavender essence, jasmine essence and squalane, and dissolving to obtain compound B;
s3: mixing water, phenoxyethanol, allantoin, tranexamic acid and panthenol, and dissolving to obtain compound C;
s4: c10-30 of acrylic acid (ester) is mixed and dissolved with alkanol acrylate cross-linked polymer, AVC, sodium polyacrylate, luba gum, dipropylene glycol and glycerol to obtain a compound D;
s5: pouring the compound C and the compound D into an emulsifying pot, adding the compound A and the compound B after uniformly stirring, adding triethanolamine after uniformly homogenizing and emulsifying, adding bisabolol, sodium acrylate/sodium acryloyldimethyl taurate copolymer, lactobacillus/soybean milk fermentation product filtrate, biological carbohydrate gum-1, cactus stem extract, beta-glucan and sodium hyaluronate after uniformly stirring.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110830614.2A CN113476395A (en) | 2021-07-22 | 2021-07-22 | Moisturizing and skin-activating cosmetic cream and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110830614.2A CN113476395A (en) | 2021-07-22 | 2021-07-22 | Moisturizing and skin-activating cosmetic cream and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113476395A true CN113476395A (en) | 2021-10-08 |
Family
ID=77942002
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110830614.2A Pending CN113476395A (en) | 2021-07-22 | 2021-07-22 | Moisturizing and skin-activating cosmetic cream and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN113476395A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114983917A (en) * | 2021-12-31 | 2022-09-02 | 安婕妤化妆品科技股份有限公司 | Soothing deep moisturizing emulsion and preparation method thereof |
| CN115006303A (en) * | 2021-12-31 | 2022-09-06 | 安婕妤化妆品科技股份有限公司 | Anti-allergy moisturizing skin-activating essence lotion and preparation method thereof |
-
2021
- 2021-07-22 CN CN202110830614.2A patent/CN113476395A/en active Pending
Non-Patent Citations (1)
| Title |
|---|
| 安婕妤化妆品科技股份有限公司: "安婕妤优能活水乳", 《国产非特殊用途化妆品备案服务平台》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114983917A (en) * | 2021-12-31 | 2022-09-02 | 安婕妤化妆品科技股份有限公司 | Soothing deep moisturizing emulsion and preparation method thereof |
| CN115006303A (en) * | 2021-12-31 | 2022-09-06 | 安婕妤化妆品科技股份有限公司 | Anti-allergy moisturizing skin-activating essence lotion and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021020887A (en) | Enhanced anti-aging cosmetic composition | |
| CN110731928A (en) | Anti-aging cosmetic composition | |
| CN113476395A (en) | Moisturizing and skin-activating cosmetic cream and preparation method thereof | |
| CN110974720A (en) | Whitening and skin-brightening composition, whitening and skin-brightening cosmetic, whitening and skin-brightening lotion and preparation method thereof, and whitening and skin-brightening emulsion and preparation method thereof | |
| CN113244144B (en) | Face cream for brightening skin color | |
| CN110946784A (en) | Skin care composition with functions of improving skin barrier function and enhancing skin health | |
| CN108451893B (en) | Toning lotion with long-acting moisturizing effect and preparation method thereof | |
| CN113509400A (en) | Skin composition and application thereof, whitening and brightening cosmetic composition and preparation method thereof | |
| CN114931543B (en) | Repairing and anti-aging essence with high content of blue copper peptide and preparation method thereof | |
| CN113616561A (en) | Composition with moisturizing and repairing effects and cosmetic | |
| CN113384497B (en) | Composition and cosmetic for double moisturizing, repairing and improving skin elasticity | |
| CN113599310B (en) | Moisturizing composition and application thereof in cosmetics | |
| CN110787074A (en) | Composition for fading fine lines | |
| CN112353705B (en) | Cosmetic composition, preparation method thereof and cosmetic with wrinkle removing and aging delaying effects | |
| CN114099397A (en) | Mud-shaped mask and preparation method thereof | |
| CN116637042A (en) | Wrinkle-removing anti-aging skin care product and preparation method and application thereof | |
| CN115068389B (en) | Multi-effect composition, essence cream and preparation method thereof | |
| CN114632028B (en) | Lifting and tightening cream and preparation method thereof | |
| CN113749972B (en) | Composition with anti-wrinkle effect and application of composition in cosmetics | |
| CN113197809B (en) | Preparation method of skin care product containing phaeodactylum and tara fermentation compound | |
| CN111773151B (en) | Whitening and freckle-removing antioxidant emulsion and preparation method thereof | |
| CN112773732A (en) | Moisturizing repair cream containing fibroin and preparation method thereof | |
| CN112933010A (en) | Whitening and repairing cream and preparation method thereof | |
| US9040097B2 (en) | Compositions for improving skin appearance | |
| CN110812262A (en) | Anti-wrinkle firming composition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20211008 |
|
| RJ01 | Rejection of invention patent application after publication |