CN113272420A - 经改进的肿瘤反应性t细胞的选择 - Google Patents
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- CN113272420A CN113272420A CN201980087609.8A CN201980087609A CN113272420A CN 113272420 A CN113272420 A CN 113272420A CN 201980087609 A CN201980087609 A CN 201980087609A CN 113272420 A CN113272420 A CN 113272420A
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
- C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
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Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862756006P | 2018-11-05 | 2018-11-05 | |
| US62/756,006 | 2018-11-05 | ||
| US201962826831P | 2019-03-29 | 2019-03-29 | |
| US62/826,831 | 2019-03-29 | ||
| US201962903629P | 2019-09-20 | 2019-09-20 | |
| US62/903,629 | 2019-09-20 | ||
| US201962924602P | 2019-10-22 | 2019-10-22 | |
| US62/924,602 | 2019-10-22 | ||
| PCT/US2019/059716 WO2020096986A2 (en) | 2018-11-05 | 2019-11-04 | Selection of improved tumor reactive t-cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113272420A true CN113272420A (zh) | 2021-08-17 |
Family
ID=69159953
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201980087609.8A Pending CN113272420A (zh) | 2018-11-05 | 2019-11-04 | 经改进的肿瘤反应性t细胞的选择 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20230039976A1 (enExample) |
| EP (1) | EP3877512A2 (enExample) |
| JP (1) | JP7854297B2 (enExample) |
| KR (1) | KR20210099573A (enExample) |
| CN (1) | CN113272420A (enExample) |
| AU (1) | AU2019375416B2 (enExample) |
| BR (1) | BR112021008266A2 (enExample) |
| CA (1) | CA3118616A1 (enExample) |
| IL (1) | IL282775A (enExample) |
| MX (1) | MX2021004953A (enExample) |
| SG (1) | SG11202104630PA (enExample) |
| TW (1) | TW202039829A (enExample) |
| WO (1) | WO2020096986A2 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118962104A (zh) * | 2022-03-15 | 2024-11-15 | 上海君赛生物科技有限公司 | 肿瘤特异性免疫细胞标志物及其用途 |
| WO2024260318A1 (zh) * | 2023-06-19 | 2024-12-26 | 苏州沙砾生物科技有限公司 | 一种肿瘤特异性细胞的富集方法和应用 |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201522097D0 (en) | 2015-12-15 | 2016-01-27 | Cellular Therapeutics Ltd | Cells |
| GB201700621D0 (en) | 2017-01-13 | 2017-03-01 | Guest Ryan Dominic | Method,device and kit for the aseptic isolation,enrichment and stabilsation of cells from mammalian solid tissue |
| WO2020232029A1 (en) * | 2019-05-13 | 2020-11-19 | Iovance Biotherapeutics, Inc. | Methods and compositions for selecting tumor infiltrating lymphocytes and uses of the same in immunotherapy |
| BR112022011795A2 (pt) | 2019-12-20 | 2022-08-30 | Instil Bio Uk Ltd | Métodos para preparar e isolar uma população terapêutica de linfócitos e para tratar câncer em um indivíduo, população terapêutica de linfócitos, bolsa criopreservada, recipiente flexível, e, sistema para extração de linfócitos |
| CA3158133A1 (en) | 2020-04-28 | 2021-11-04 | Lyell Immunopharma, Inc. | Methods for culturing cells |
| CA3177413A1 (en) * | 2020-05-04 | 2021-11-11 | Michelle SIMPSON-ABELSON | Selection of improved tumor reactive t-cells |
| CA3176826A1 (en) * | 2020-05-04 | 2021-11-11 | Iovance Biotherapeutics, Inc. | Processes for production of tumor infiltrating lymphocytes and uses of the same in immunotherapy |
| WO2022076606A1 (en) * | 2020-10-06 | 2022-04-14 | Iovance Biotherapeutics, Inc. | Treatment of nsclc patients with tumor infiltrating lymphocyte therapies |
| JP2023546359A (ja) * | 2020-10-06 | 2023-11-02 | アイオバンス バイオセラピューティクス,インコーポレイテッド | 腫瘍浸潤リンパ球療法によるnsclc患者の治療 |
| EP4262828A1 (en) * | 2020-12-18 | 2023-10-25 | Instil Bio (Uk) Limited | Tumor infiltrating lymphocytes and anti-cd47 therapeutics |
| EP4301138A2 (en) | 2021-03-05 | 2024-01-10 | Iovance Biotherapeutics, Inc. | Tumor storage and cell culture compositions |
| JP2024519029A (ja) | 2021-05-17 | 2024-05-08 | アイオバンス バイオセラピューティクス,インコーポレイテッド | Pd-1遺伝子編集された腫瘍浸潤リンパ球及び免疫療法におけるその使用 |
| US20240035027A1 (en) * | 2022-05-04 | 2024-02-01 | University Of Massachusetts | Oligonucleotides for pms2 modulation |
| WO2024054518A1 (en) * | 2022-09-07 | 2024-03-14 | Nextvivo, Inc. | Systems and methods of enhancing tumor-reactive immune populations with organoids |
| EP4612277A1 (en) | 2022-11-04 | 2025-09-10 | Iovance Biotherapeutics, Inc. | Methods for tumor infiltrating lymphocyte (til) expansion related to cd39/cd103 selection |
| KR102867582B1 (ko) * | 2023-11-13 | 2025-10-14 | 주식회사 박셀바이오 | 신규한 골수 침윤 림프구 집단 및 이의 제조방법 |
| WO2025221934A1 (en) * | 2024-04-17 | 2025-10-23 | Ctrl Therapeutics Usa, Inc. | Compositions and methods of enhancing tumor reactive lymphocytes |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018081473A1 (en) * | 2016-10-26 | 2018-05-03 | Iovance Biotherapeutics, Inc. | Restimulation of cryopreserved tumor infiltrating lymphocytes |
| TW201839129A (zh) * | 2017-03-29 | 2018-11-01 | 美商艾歐凡斯生物治療公司 | 產生腫瘤浸潤淋巴球的方法及其在免疫治療中的應用 |
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| EP3877512A2 (en) | 2021-09-15 |
| JP7854297B2 (ja) | 2026-05-01 |
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| US20230039976A1 (en) | 2023-02-09 |
| AU2019375416A1 (en) | 2021-05-27 |
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| IL282775A (en) | 2021-06-30 |
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| CA3118616A1 (en) | 2020-05-14 |
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| KR20210099573A (ko) | 2021-08-12 |
| WO2020096986A3 (en) | 2020-06-18 |
| TW202039829A (zh) | 2020-11-01 |
| AU2019375416B2 (en) | 2026-02-19 |
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