CN113166245B - SIRPα结合蛋白及其使用方法 - Google Patents

SIRPα结合蛋白及其使用方法 Download PDF

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CN113166245B
CN113166245B CN201980075667.9A CN201980075667A CN113166245B CN 113166245 B CN113166245 B CN 113166245B CN 201980075667 A CN201980075667 A CN 201980075667A CN 113166245 B CN113166245 B CN 113166245B
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antibody
seq
antigen
binding fragment
amino acid
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CN113166245A (zh
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马汉·阿巴西恩
亨利·H·陈
劳雷·埃斯考伯特
古斯塔沃·费内蒂
坎德萨米·哈里哈兰
莫妮卡·惠玲·梁
康斯坦提诺斯·马夫罗马蒂斯
大卫·P·米科隆
希瑟·K·雷蒙
卡洛·史蒂文·桑托斯
孙正勋
克里斯蒂娜·瓦莱丽·特劳特
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Celgene Corp
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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    • C07K16/2887—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
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    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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CN201980075667.9A 2018-09-27 2019-09-24 SIRPα结合蛋白及其使用方法 Active CN113166245B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862737782P 2018-09-27 2018-09-27
US62/737,782 2018-09-27
US201962853997P 2019-05-29 2019-05-29
US62/853,997 2019-05-29
PCT/US2019/052604 WO2020068752A1 (en) 2018-09-27 2019-09-24 SIRPα BINDING PROTEINS AND METHODS OF USE THEREOF

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CN113166245A CN113166245A (zh) 2021-07-23
CN113166245B true CN113166245B (zh) 2024-12-20

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EP (1) EP3856787A4 (https=)
JP (2) JP7266670B2 (https=)
KR (1) KR20210086619A (https=)
CN (1) CN113166245B (https=)
AU (1) AU2019349651B2 (https=)
BR (1) BR112021005585A2 (https=)
CA (1) CA3113798A1 (https=)
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