CN112807271A - Moisturizing composition, essence and preparation method of moisturizing composition - Google Patents

Moisturizing composition, essence and preparation method of moisturizing composition Download PDF

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CN112807271A
CN112807271A CN202110308880.9A CN202110308880A CN112807271A CN 112807271 A CN112807271 A CN 112807271A CN 202110308880 A CN202110308880 A CN 202110308880A CN 112807271 A CN112807271 A CN 112807271A
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composition
parts
moisturizing
essence
extract
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CN112807271B (en
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杨惠
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Yifan Shanghai Industrial Co ltd
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Yifan Shanghai Industrial Co ltd
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    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
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    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
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    • A61K8/73Polysaccharides
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    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/731Cellulose; Quaternized cellulose derivatives
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    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9755Gymnosperms [Coniferophyta]
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    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9755Gymnosperms [Coniferophyta]
    • A61K8/9767Pinaceae [Pine family], e.g. pine or cedar
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    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
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    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
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    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A61K8/988Honey; Royal jelly, Propolis
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    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
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Abstract

The application relates to the field of cosmetics, and particularly discloses a moisturizing composition, essence and a preparation method of the moisturizing composition. A moisturizing composition comprises the following raw materials in parts by weight, which are stored separately: 0.1-0.5 part of panthenol; 0.1-10 parts of betaine; 0.1-5 parts of a first composition; 0.01-2 parts of a second composition; 0.01-5 parts of a third composition; 0.001-0.5 parts of barley malt extract; 0.5-10 parts of cedar extract; 0.01-5 parts of a fourth composition; 0.001-1 part of micromolecular sodium hyaluronate; 0.001-0.5 parts of tremella heteropolysaccharide. Adding 83 to 86 parts by weight of deionized water; 0.15-0.25 part of hydroxyethyl cellulose; 0.1-0.2 parts of xanthan gum; 4-6 parts of glycerol; 5-6 parts of 1, 3-propylene glycol; 0.4-0.6 part of p-hydroxyacetophenone; 0.8-1 part of trehalose; 0.5-0.7 part of 1, 2-hexanediol to obtain the essence. The moisturizing composition can be applied to face cleansing milk, cream, lotion, essence, emulsion, facial mask, color cosmetics and the like, wherein the obtained moisturizing essence has an excellent moisturizing effect.

Description

Moisturizing composition, essence and preparation method of moisturizing composition
Technical Field
The application relates to the field of cosmetics, in particular to a moisturizing composition, essence and a preparation method thereof.
Background
The cosmetic composition is mostly applied to face cleansing cream, lotion, essence, emulsion, mask and the like, and the cosmetic essence generally refers to essence which is a skin care product with certain efficacy for the face.
The Chinese invention patent application with the publication number of CN111888281A discloses a nourishing and moisturizing essence, which comprises the following components in percentage by mass: 2-5% of nicotinamide; 0.5-10% of astaxanthin; 5-25% of a skin conditioner; 5-20% of a humectant; the balance of water, and the nourishing and moisturizing essence specifically comprises the following components: 2.5-3.5% of nicotinamide; 1-4% of astaxanthin; 8-20% of a skin conditioner; 5-15% of a humectant; the balance of water, preservative with the mass percent less than or equal to 1 percent, thickener with the mass percent less than 1 percent, and essence with the mass percent less than or equal to 1 percent.
In view of the above-mentioned related technologies, the inventors believe that the active ingredients in the essence can penetrate into the skin basement, but have a defect in self-film-forming property, so that a protective film is difficult to form on the skin surface, moisture is difficult to retain for a long time, and the moisture retention performance still needs to be improved.
Disclosure of Invention
In order to improve the moisturizing performance of cosmetic essence, the application provides a moisturizing composition, essence and a preparation method thereof.
In a first aspect, the present application provides a moisturizing composition, using the following technical scheme:
the moisturizing composition is characterized by comprising the following raw materials in parts by weight which are stored separately:
0.1-0.5 part of panthenol;
0.1-10 parts of betaine;
0.1-5 parts of a first composition;
0.01-2 parts of a second composition;
0.01-5 parts of a third composition;
0.001-0.5 parts of barley malt extract;
0.5-10 parts of cedar extract;
0.01-5 parts of a fourth composition;
0.001-1 part of micromolecular sodium hyaluronate;
0.001-0.5 parts of tremella heteropolysaccharide.
By adopting the technical scheme, the panthenol is also called as provitamin B5, can moisturize the stratum corneum, reduce the water loss of the skin, improve the roughness and dryness of the skin, is beneficial to keeping water and is an important nutrient element in the skin of a human body. The tremella heteropolysaccharide has a spatial network structure in the solution, has excellent film forming property, helps to lock more water and is not easy to evaporate, and can form a layer of uniform film with a certain thickness on the surface of the skin, so that the skin water can be locked for a long time. Meanwhile, the panthenol and the tremella heteropolysaccharide can play a good role in compounding and synergism, help to generate fibroblasts in a middle layer (a layer formed by wrinkles) of the skin, promote the development and generation of collagen, glycan and elastin, can form a stable protective film structure, help to maintain the skin barrier function, and further play an excellent moisturizing effect.
Meanwhile, the betaine can rapidly permeate into skin cells to moisten and luster the skin, is a safe humectant, and can promote the permeation of other effective components. The barley malt extract is rich in vitamin E, crude protein and the like, is rich in various skin benefiting components, and is beneficial to improving the moisture content and the total collagen of skin. The cedar extract has antibacterial, soothing, antiinflammatory, astringent, refreshing, inflammation relieving, skin repairing promoting, and soothing effects.
Preferably, the panthenol is 0.2 part, the first composition is 0.2 part, the second composition is 0.1 part, and the tremella heteropolysaccharide is 0.01 part.
By adopting the technical scheme, the components in the selected proportion can play an excellent moisturizing role in the application process.
Preferably, the first composition comprises at least the following raw materials: saccharide isomerate, water, citric acid and sodium citrate.
By adopting the technical scheme, the saccharide isomer is a natural humectant extracted from a natural plant saccharide complex, is similar to a carbohydrate complex in a human body, has good skin-friendly performance, can be combined with lysine (free-amino) in keratin, and can deeply moisturize. The citric acid and sodium citrate are mainly used for regulating the pH value of cosmetics, can resist oxidation and corrosion, can promote the synthesis of NMF (natural moisturizing factor) and hyaluronic acid, improve the skin water retention capacity and improve the natural skin moisture retention capacity.
Preferably, the second composition comprises at least the following raw materials: water, honey extract and 1, 3-propanediol.
By adopting the technical scheme, the honey extract contains gluconic acid with high concentration, is beneficial to softening cutin, can help trace elements to absorb and can promote the effect of moisturizing components on skin.
Preferably, the third composition comprises at least the following raw materials: butylene glycol, water and cedar bud extract.
By adopting the technical scheme, the cedar bud extract has rich nutrient substances, vitamins and mineral substances, is a source of high-energy and high-nutrient elements of the skin, and can supplement water and establish the self capacity of the skin to keep hydration. Meanwhile, the cedar bud extract can help the epidermis differentiation and the skin barrier repair, improve the cohesion of keratinocytes, ensure the recovery of the skin barrier function, and enable the skin to optimally preserve the moisture content and better self-control.
Preferably, the fourth composition comprises at least the following raw materials: water, butylene glycol, 1, 2-hexanediol, folic acid, sodium hyaluronate, and a bacillus/soy fermentation product extract.
By adopting the technical scheme, folic acid can promote the metabolism of protein in a human body, and can play the roles of anti-allergy, moisture retention and cell growth promotion when being used on skin. The sodium hyaluronate can permeate into the epidermis layer and the dermis layer, and further can help the skin to moisturize. The bacillus/soybean fermentation product extract is a good humectant and skin conditioner, and is beneficial to ensuring that the moisturizing essence has a good moisturizing effect.
Preferably, the moisturizing composition comprises the following raw materials in parts by weight, which are separately stored:
0.2 part of panthenol;
2 parts of betaine;
0.2 part of first composition;
0.1 part of a second composition;
0.1 part of a third composition;
0.1 part of barley malt extract;
0.5 part of cedar extract;
0.2 part of a fourth composition;
0.01 part of micromolecular sodium hyaluronate;
0.01 part of tremella heteropolysaccharide.
By adopting the technical scheme, the moisturizing composition obtained by optimizing the proportion can exert excellent moisturizing effect in the application process.
In a second aspect, the present application provides an essence, which adopts the following technical scheme:
the essence is prepared by mixing the following raw materials in parts by weight:
0.1-0.5 part of panthenol;
0.1-10 parts of betaine;
0.1-5 parts of a first composition;
0.01-2 parts of a second composition;
0.01-5 parts of a third composition;
0.001-0.5 parts of barley malt extract;
0.5-10 parts of cedar extract;
0.01-5 parts of a fourth composition;
0.001-1 part of micromolecular sodium hyaluronate;
0.001-0.5 parts of tremella heteropolysaccharide;
83-86 parts of deionized water;
0.15-0.25 part of hydroxyethyl cellulose;
0.1-0.2 parts of xanthan gum;
4-6 parts of glycerol;
5-6 parts of 1, 3-propylene glycol;
0.4-0.6 part of p-hydroxyacetophenone;
0.8-1 part of trehalose;
0.5-0.7 part of 1, 2-hexanediol.
By adopting the technical scheme, the hydroxyethyl cellulose is a good thickening agent, and is beneficial to fully mixing raw materials of all components. The xanthan gum is beneficial to fully mixing the raw materials of all components, and has good compatibility with each other. The p-hydroxyacetophenone is an excellent preservative, has oxidation resistance and stable performance, and is beneficial to improving the overall quality of the moisturizing essence. Meanwhile, the moisturizing composition is matched with each auxiliary ingredient, so that the essence with stable and excellent performance can be obtained.
Preferably, the essence is prepared by mixing the following raw materials in parts by weight:
0.1 part of panthenol;
2 parts of betaine;
0.2 part of first composition;
0.1 part of a second composition;
0.1 part of a third composition;
0.1 part of barley malt extract;
0.5 part of cedar extract;
0.2 part of a fourth composition;
0.01 part of micromolecular sodium hyaluronate;
0.01 part of tremella heteropolysaccharide;
84.68 parts of deionized water;
0.2 part of hydroxyethyl cellulose;
0.1 part of xanthan gum;
5 parts of glycerol;
5 parts of 1, 3-propylene glycol;
0.5 part of p-hydroxyacetophenone;
1 part of trehalose;
0.6 part of 1, 2-hexanediol.
By adopting the technical scheme, the components in the selected proportion can play an excellent moisturizing role in the application process.
In a third aspect, the application provides a preparation method of essence, which adopts the following technical scheme:
a preparation method of essence comprises the following steps:
(1) preparing deionized water, hydroxyethyl cellulose, xanthan gum, glycerol, 1, 3-propylene glycol, p-hydroxyacetophenone, trehalose, panthenol, betaine, small-molecular sodium hyaluronate and tremella heteropolysaccharide in corresponding parts by weight according to a ratio, uniformly mixing and stirring at the stirring temperature of 75-80 ℃, the stirring speed of 200-400rpm and the stirring time of 25-35min to obtain a semi-finished product;
(2) and (3) cooling the semi-finished product in the step (1) to 35-40 ℃, respectively weighing the first composition, the second composition, the third composition, the fourth composition, the barley malt extract, the cedar extract and 1, 2-hexanediol in corresponding parts by weight, uniformly mixing and stirring at the stirring speed of 100-150rpm for 10-15min to obtain the essence.
By adopting the technical scheme, the preparation method is beneficial to fully mixing the raw materials of all the components together, is simple to operate, has high production efficiency on the premise of ensuring good quality of the moisturizing essence, and has good applicability as a whole.
In summary, the present application has the following beneficial effects:
according to the application, the panthenol and tremella heteropolysaccharide have a compounding synergistic effect, and the first composition and the second composition are used as auxiliary materials, so that the growth of epidermal cells and fibroblasts and the activation and renewal of epidermal cells are stimulated in a middle layer (a layer formed by wrinkles) of skin, the development and production of collagen, polysaccharide and structural protein can be promoted, a stable protective film structure can be formed, the skin barrier function can be maintained, the skin can be repaired and regulated to be normalized, and an excellent moisturizing effect can be achieved.
Detailed Description
The present application will be described in further detail with reference to examples.
Examples
Example 1
The essence comprises the following components in parts by weight (kg) shown in table 1, and is prepared by the following steps:
(1) preparing deionized water, hydroxyethyl cellulose, xanthan gum, glycerol, 1, 3-propylene glycol, p-hydroxyacetophenone, trehalose, panthenol, betaine, small-molecular sodium hyaluronate and tremella heteropolysaccharide in corresponding parts by weight according to a ratio, mixing and stirring uniformly, wherein the stirring temperature is 80 ℃, the stirring speed is 300rpm, and the stirring time is 30min to obtain a semi-finished product;
(2) and (3) cooling the semi-finished product in the step (1) to 40 ℃, weighing the first composition, the second composition, the third composition, the fourth composition, the barley malt extract, the cedar extract and 1, 2-hexanediol in corresponding parts by weight respectively, mixing and stirring uniformly at the stirring speed of 100rpm for 10min, and thus obtaining the moisturizing essence.
Note: the Panthenol in the above steps is purchased from D-Panthenol (D-Panthenol) of Usum Kazuki commercial Co., Ltd; the micromolecular sodium hyaluronate is purchased from enzyme-digested oligomeric sodium hyaluronate of Huaxi biotechnology corporation; tremella heteropolysaccharide is purchased from Tremella polymer heteropolysaccharide-WSK of Shanghai Huiwen biotechnology Limited; the xanthan gum is purchased from Keltrol CG-T of Shanghai Luxiao Biotech limited; barley malt extract is obtained from highland barley seed sprout 60 of Shanghai Rui xi commercial Co., Ltd; cedar extract was purchased from SkinEmo DC of billows biotechnology limited, shanghai; the first composition is a natural polysaccharide purchased from Shanghai autumn-pressed commercial and trade company Limited
Figure BDA0002988880010000062
The second composition was purchased from FE HONEY PG of Shanghai hong Jiu corporation; the third composition was purchased from GATULINE RENEW, Shanghai Puen Biotechnology Ltd; the fourth composition was obtained from MilleCare FE, a chemical company, qian hei.
Examples 2 to 7
The essence is different from the essence in example 1 in that the components and the corresponding parts by weight are shown in table 1.
TABLE 1 Components and parts by weight thereof in examples 1-7
Figure BDA0002988880010000061
Figure BDA0002988880010000071
Comparative example
Comparative example 1
An essence is different from that of example 1 in that the moisturizing composition does not contain panthenol, tremella heteropolysaccharide, the first composition and the second composition.
Comparative example 2
An essence, which is different from that of example 1 in that the moisturizing composition does not contain panthenol, tremella heteropolysaccharide and a second composition.
Comparative example 3
A serum, which is different from example 1 in that panthenol, the first composition and the second composition are not contained in the moisturizing composition.
Comparative example 4
The essence is different from the essence in example 1 in that the moisturizing composition does not contain tremella heteropolysaccharide, the first composition and the second composition.
Comparative example 5
An essence, which is different from that of example 1 in that the moisturizing composition does not contain panthenol, tremella heteropolysaccharide and the first composition.
Comparative example 6
An essence, which is different from the essence in example 1 in that the moisturizing composition does not contain panthenol and tremella heteropolysaccharide.
Comparative example 7
An essence, which is different from example 1 in that panthenol is not contained in the moisturizing composition.
Comparative example 8
An essence is different from the essence in example 1 in that the moisturizing composition does not contain tremella heteropolysaccharide.
Comparative example 9
An essence, which is different from example 1 in that the moisturizing composition does not contain the second composition.
Comparative example 10
An essence, which is different from example 1 in that the moisturizing composition does not contain the first composition.
Comparative example 11
An essence which is different from that of example 1 in that panthenol is 0.09 parts.
Comparative example 12
An essence, which is different from example 1 in that panthenol is 5.1 parts.
Comparative example 13
An essence, which is different from example 1 in that the first composition is 0.09 parts.
Comparative example 14
An essence, which is different from example 1 in that the first composition is 5.1 parts.
Comparative example 15
An essence, which is different from example 1 in that the second composition is 0.009 parts.
Comparative example 16
An essence, which is different from example 1 in that the second composition is 2.01 parts.
Comparative example 17
The essence is different from the essence in example 1 in that 0.501 parts of tremella heteropolysaccharide is added.
Comparative example 18
The essence is different from the essence in example 1 in that 0.0009 part of tremella heteropolysaccharide is added.
Performance testing test samples: the essences obtained in examples 1 to 7 were used as example test samples 1 to 7, and the essences obtained in comparative examples 1 to 18 were used as comparative example control samples 1 to 18.
Skin moisture content test principle:
the first efficacy test index of the invention adopts a Corneometer CM 825 probe of a German CK skin tester to evaluate the efficacy. The probe uses the international Corneometer method: capacitive method. Due to the completely different dielectric constants of water (81) and other substances (< 7), the moisture content of the sample was obtained by measuring the change in capacitance exhibited by the capacitor. A glass plate in the probe separates the metal track (gold) on top of the probe from the skin to prevent conduction of current in the sample. An electromagnetic field is gradually generated which is mutually attracted between the tracks. One orbital establishes an electron excess (-) and the other lacks electrons (+). During the measurement, the scattered field penetrates the first layer of the skin and determines the capacitance, thus measuring the moisture content.
Skin transdermal water loss (TEWL) test principle:
the second index of the efficacy test of the invention, the transdermal water loss (TEWL) is an indispensable parameter for evaluating the skin barrier function and is a basic measurement for various applications. Some water loss from the skin is as part of normal skin metabolism, however once the skin barrier function is slightly compromised, water loss increases (even with minimal damage not visible to the human eye). The experiment was measured using the Tewameter TM 300 probe of the german CK skin tester, which is the most accepted measuring instrument worldwide for evaluation of the transepidermal water loss (TEWL). The Tewameter probe measures the density gradient of skin moisture evaporation directly with two pairs of sensors (temperature and relative humidity) inside the hollow cylinder, an open cavity measurement. The open cavity measurement method is the only method to continuously evaluate the water loss TEWL without affecting the microenvironment. The physical basis for the measurement was the diffusion law found by Adolf Fick in 1855.
Calculating the formula:
a ═ surface [ m2]M is moisture transport [ g ═]T is time [ h]D ═ diffusion constant [ ═ 0.0877g/m (h (mmhg))]P is atmospheric vapour pressure [ mmHg ]]X is the distance from the skin surface to the measurement point [ m]
The diffusion flow dm/dt represents the mass delivered per square centimeter over time, and is proportional to the change in area a and concentration/distance dc/dx. D is the diffusion coefficient of water vapor in air. This law is only valid in homogeneous diffusion regions, presumably formed by hollow cylinders. The density gradient thus generated is measured indirectly by two pairs of sensors (temperature and relative humidity) and analyzed by a microprocessor and expressed as the evaporation capacity g/h/m2
The test method comprises the following steps: the test environment of the experiment is kept constant, the temperature is 20 ℃, and the relative humidity is 50%. Because the heat radiation can cause inaccurate measurement, the measurement is not kept under the direct light of lamplight and sunlight; the experiment selects 20 subjects with healthy skin, 20-35 years old and half male and female. Testing the moisture content transdermal water dispersion amount of the test sample and the control sample, and calculating the change average value of each sample after 20 subjects use for 1 hour and the change average value of each sample for 4 hours to carry out related judgment; according to the informed consent of the testees, the testees are required to be simply cleaned before testing, the testing time is 9 am, 0.5ml of essence of the test sample 1 and the test sample 2 is weighed on the first day, the essence is soaked in 2cm x 2cm non-woven fabric membrane cloth and covers the cheek skin of the first testee for 15min, the non-woven fabric is taken off, the operation is stood for 10min, the moisture content and the transdermal moisture loss are respectively measured in two testing areas of the cheek, the moisture content and the transdermal moisture loss of the test sample and the control sample are respectively recorded as initial values, and the operation is repeated until the testing of 20 testees is completed. The operation was repeated for 1h and 4h after use, and the data were recorded. After 3 days, this procedure was repeated, and two samples were sequentially selected in the order of test samples 3-7 and control samples 1-18 for testing in the left cheek and right cheek regions, respectively, with the last control sample 18 being tested separately and the data being recorded until all samples were completed.
And (3) test result calculation:
mean change in moisture content after 1h Δ 1 ═ after subject 1 used 1 h-initial moisture content before subject 1 used/initial moisture content before subject 1 used + (after subject 2 used 1 h-initial moisture content before subject 2 used)/initial moisture content before subject 2 used +/. 9. + (after subject 20 used 1 h-initial moisture content before subject 20 used)/initial moisture content before subject 20 used ]/100%/mean change in moisture content after 4h 20 Δ 2 [ (after subject 1 used 4 h-initial moisture content before subject 1 used)/initial moisture content before subject 1 used + (after subject 2 used 4 h-initial moisture content before subject 2 used)/initial moisture content after 4h for subject 2 A. + (initial moisture content after subject 20 used 4 h-initial moisture content before subject 20 used)/initial moisture content before subject 20 used 100%/20 average value of change in transdermal water dispersion (TWEL) after 1h ═ [ (initial moisture dispersion after subject 1 used 1 h-initial moisture dispersion before subject 1 used)/initial moisture dispersion before subject 1 used + (initial moisture dispersion after subject 2 used 1 h-initial moisture dispersion before subject 2 used)/initial water dispersion before subject 2 used +/(initial moisture dispersion after subject 20 used 1 h-initial moisture dispersion before subject 20 used)/initial water dispersion before subject 20 used ] +.9. + (initial moisture dispersion after subject 20 used 1 h-initial moisture dispersion before subject 20 used)/initial water dispersion before subject 20 used ] +/20.
Mean change in transdermal water dispersion (TWEL) after 4h, ([ water dispersion after 4h in subject 1-initial water dispersion before use in subject 1)/initial water dispersion before use in subject 1 + (water dispersion after 4h in subject 2-initial water dispersion before use in subject 2)/initial water dispersion after use in subject 2) +. + -. (water dispersion after 4h in subject 20-initial water dispersion before use in subject 20)/initial water dispersion before use in subject 20) ] 100%/20.
And (3) test results: from the comparison between the test results of example 1 and examples 2 to 7, example 1 is the optimal mixture ratio combination of the components of the essence, and the mixture ratio of the components of the moisturizing composition is also the optimal mixture ratio combination. Compared with the test results of example 1 and comparative example 1, the product has good moisturizing effect by using panthenol and tremella heteropolysaccharide and assisting with the first composition and the second composition. The comparison of the test results of the example 1 and the comparative examples 2 to 5 shows that the moisturizing effect of the comparative example 2 and the comparative example 5 is most obviously reduced, and the panthenol and the tremella heteropolysaccharide are not contained in the moisturizing cream, and the comparison of the test results of the comparative example 6 and the comparative examples 9 to 10 shows that the panthenol and the tremella heteropolysaccharide are matched for use and cannot be used at all. On the basis, the test results of the comparative example 6 and the comparative examples 7 to 8 show that the panthenol and the tremella heteropolysaccharide have good synergistic effect.
Mean change in moisture content after 1h and after 4h of administration to 220 subjects in Table
Figure BDA0002988880010000101
Figure BDA0002988880010000111
Figure BDA0002988880010000121
Mean change in transdermal Water Dispersion 1h and 4h after administration to 320 subjects in Table
Figure BDA0002988880010000122
Figure BDA0002988880010000131
The present embodiment is only for explaining the present application, and it is not limited to the present application, and those skilled in the art can make modifications of the present embodiment without inventive contribution as needed after reading the present specification, but all of them are protected by patent law within the scope of the claims of the present application.

Claims (10)

1. The moisturizing composition is characterized by comprising the following raw materials in parts by weight which are stored separately:
0.1-0.5 part of panthenol;
0.1-10 parts of betaine;
0.1-5 parts of a first composition;
0.01-2 parts of a second composition;
0.01-5 parts of a third composition;
0.001-0.5 parts of barley malt extract;
0.5-10 parts of cedar extract;
0.01-5 parts of a fourth composition;
0.001-1 part of micromolecular sodium hyaluronate;
0.001-0.5 parts of tremella heteropolysaccharide.
2. The moisturizing composition of claim 1, characterized in that: the content of the D-panthenol is 0.2 part, the content of the first composition is 0.2 part, the content of the second composition is 0.1 part, and the content of the tremella heteropolysaccharide is 0.01 part.
3. The moisturizing composition of claim 1, characterized in that: the first composition comprises at least the following raw materials: saccharide isomerate, water, citric acid and sodium citrate.
4. The moisturizing composition of claim 1, characterized in that: the second composition at least comprises the following raw materials: water, honey extract and 1, 3-propanediol.
5. The moisturizing composition of claim 1, characterized in that: the third composition at least comprises the following raw materials: butylene glycol, water and cedar bud extract.
6. The moisturizing composition of claim 1, characterized in that: the fourth composition at least comprises the following raw materials: water, butylene glycol, 1, 2-hexanediol, folic acid, sodium hyaluronate, and a bacillus/soy fermentation product extract.
7. The moisturizing composition of claim 1, characterized in that: the moisturizing composition comprises the following raw materials in parts by weight which are stored separately:
0.2 part of panthenol;
2 parts of betaine;
0.2 part of first composition;
0.1 part of a second composition;
0.1 part of a third composition;
0.1 part of barley malt extract;
0.5 part of cedar extract;
0.2 part of a fourth composition;
0.01 part of micromolecular sodium hyaluronate;
0.01 part of tremella heteropolysaccharide.
8. The essence is characterized in that: the moisturizing composition as claimed in any one of claims 1 to 7, which is prepared by mixing the following raw materials in parts by weight:
0.1-0.5 part of panthenol;
0.1-10 parts of betaine;
0.1-5 parts of a first composition;
0.01-2 parts of a second composition;
0.01-5 parts of a third composition;
0.001-0.5 parts of barley malt extract;
0.5-10 parts of cedar extract;
0.01-5 parts of a fourth composition;
0.001-1 part of micromolecular sodium hyaluronate;
0.001-0.5 parts of tremella heteropolysaccharide;
83-86 parts of deionized water;
0.15-0.25 part of hydroxyethyl cellulose;
0.1-0.2 parts of xanthan gum;
4-6 parts of glycerol;
5-6 parts of 1, 3-propylene glycol;
0.4-0.6 part of p-hydroxyacetophenone;
0.8-1 part of trehalose;
0.5-0.7 part of 1, 2-hexanediol.
9. The essence of claim 1, wherein: the composition is prepared by mixing the following raw materials in parts by weight:
0.1 part of panthenol;
2 parts of betaine;
0.2 part of first composition;
0.1 part of a second composition;
0.1 part of a third composition;
0.1 part of barley malt extract;
0.5 part of cedar extract;
0.2 part of a fourth composition;
0.01 part of micromolecular sodium hyaluronate;
0.01 part of tremella heteropolysaccharide;
84.68 parts of deionized water;
0.2 part of hydroxyethyl cellulose;
0.1 part of xanthan gum;
5 parts of glycerol;
5 parts of 1, 3-propylene glycol;
0.5 part of p-hydroxyacetophenone;
1 part of trehalose;
0.6 part of 1, 2-hexanediol.
10. The method for preparing the essence of claim 8, comprising the steps of:
(1) preparing deionized water, hydroxyethyl cellulose, xanthan gum, glycerol, 1, 3-propylene glycol, p-hydroxyacetophenone, trehalose, panthenol, betaine, small-molecular sodium hyaluronate and tremella heteropolysaccharide in corresponding parts by weight according to a ratio, uniformly mixing and stirring at the stirring temperature of 75-80 ℃, the stirring speed of 200-400rpm and the stirring time of 25-35min to obtain a semi-finished product;
(2) and (3) cooling the semi-finished product in the step (1) to 35-40 ℃, respectively weighing the first composition, the second composition, the third composition, the fourth composition, the barley malt extract, the cedar extract and 1, 2-hexanediol in corresponding parts by weight, uniformly mixing and stirring at the stirring speed of 100-150rpm for 10-15min to obtain the essence.
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115317391A (en) * 2022-07-27 2022-11-11 旖帆(上海)实业有限公司 Anti-wrinkle composition, anti-wrinkle essence cream applied to anti-wrinkle composition and preparation method of anti-wrinkle essence cream

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006515311A (en) * 2003-01-27 2006-05-25 ガットフォース・エスアーエス Cedar sprout extract
CN107648109A (en) * 2017-10-20 2018-02-02 伊婕 A kind of whitening and moisturizing specially imitates Essence and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006515311A (en) * 2003-01-27 2006-05-25 ガットフォース・エスアーエス Cedar sprout extract
CN107648109A (en) * 2017-10-20 2018-02-02 伊婕 A kind of whitening and moisturizing specially imitates Essence and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115317391A (en) * 2022-07-27 2022-11-11 旖帆(上海)实业有限公司 Anti-wrinkle composition, anti-wrinkle essence cream applied to anti-wrinkle composition and preparation method of anti-wrinkle essence cream
CN115317391B (en) * 2022-07-27 2023-11-14 旖帆(上海)实业有限公司 Anti-wrinkle composition, anti-wrinkle essence cream applied by anti-wrinkle composition and preparation method of anti-wrinkle essence cream

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