CN112262214A - 病毒载体及包装细胞系 - Google Patents

病毒载体及包装细胞系 Download PDF

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Publication number
CN112262214A
CN112262214A CN201980037729.7A CN201980037729A CN112262214A CN 112262214 A CN112262214 A CN 112262214A CN 201980037729 A CN201980037729 A CN 201980037729A CN 112262214 A CN112262214 A CN 112262214A
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cell
nucleic acid
receptor
lentiviral
lentiviral particle
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A·沙伦伯格
L·贝茨
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Youmojia Biopharmaceutical Co ltd
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Youmojia Biopharmaceutical Co ltd
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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CN201980037729.7A 2018-04-12 2019-04-11 病毒载体及包装细胞系 Pending CN112262214A (zh)

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US201862656823P 2018-04-12 2018-04-12
US62/656,823 2018-04-12
PCT/US2019/026923 WO2019200056A2 (en) 2018-04-12 2019-04-11 Viral vectors and packaging cell lines

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CN112262214A true CN112262214A (zh) 2021-01-22

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US (3) US12215337B2 (enExample)
EP (1) EP3775231A2 (enExample)
JP (2) JP7721436B2 (enExample)
CN (1) CN112262214A (enExample)
AU (2) AU2019252285B2 (enExample)
BR (1) BR112020020887A2 (enExample)
CA (1) CA3096458A1 (enExample)
IL (1) IL277936A (enExample)
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Cited By (2)

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CN114981441A (zh) * 2019-10-16 2022-08-30 优莫佳生物制药股份有限公司 用于通用受体疗法的逆转录病毒载体
US12215337B2 (en) 2018-04-12 2025-02-04 Umoja Biopharma, Inc. Viral vectors and packaging cell lines

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US11111505B2 (en) 2016-03-19 2021-09-07 Exuma Biotech, Corp. Methods and compositions for transducing lymphocytes and regulating the activity thereof
US11325948B2 (en) 2016-03-19 2022-05-10 Exuma Biotech Corp. Methods and compositions for genetically modifying lymphocytes to express polypeptides comprising the intracellular domain of MPL
US12144850B2 (en) 2016-04-08 2024-11-19 Purdue Research Foundation Methods and compositions for car T cell therapy
ES3010559T3 (en) 2017-02-28 2025-04-03 Endocyte Inc Compositions and methods for car t cell therapy
JP7549303B2 (ja) 2018-01-22 2024-09-11 エンドサイト・インコーポレイテッド Ｃａｒ ｔ細胞の使用方法
CN112105382A (zh) 2018-02-23 2020-12-18 恩多塞特公司 用于car t细胞疗法的顺序方法
WO2020106992A1 (en) 2018-11-21 2020-05-28 Umoja Biopharma, Inc. Multicistronic vector for surface engineering lentiviral particles
CA3165713A1 (en) 2020-01-30 2021-08-05 Andrew Scharenberg Bispecific transduction enhancer
US20230201440A1 (en) * 2020-05-08 2023-06-29 Innovative Cellular Therapeutics Holdings, Ltd. System and method for gene and/or cellular therapy
MX2023005876A (es) * 2020-11-20 2023-07-20 Umoja Biopharma Inc Sistema de vector para administracion de multiples polinucleotidos y usos del mismo.
AU2022212952A1 (en) 2021-01-27 2023-08-10 Umoja Biopharma, Inc. Lentivirus for generating cells expressing anti-cd19 chimeric antigen receptor
IL316109A (en) * 2022-05-06 2024-12-01 Umoja Biopharma Inc Viral particle with mixed molecules on the surface
IL320319A (en) * 2022-11-04 2025-06-01 Umoja Biopharma Inc Lentivirus particles displaying fusion molecules and their uses
WO2024097992A2 (en) * 2022-11-04 2024-05-10 Umoja Biopharma, Inc. Particles displaying adhesion-molecule fusions
WO2024215989A1 (en) 2023-04-14 2024-10-17 Sotio Biotech Inc. ENGINEERED IMMUNE CELLS FOR TREATING CANCER IN COMBINATION WITH IL-2/IL-15 RECEPTOR βγ AGONISTS
WO2024215987A1 (en) 2023-04-14 2024-10-17 Sotio Biotech Inc. IMMUNE CELLS FOR TREATING CANCER IN COMBINATION WITH IL-15/IL-15Rα CONJUGATES
WO2024223847A1 (en) 2023-04-27 2024-10-31 Miltenyi Biotec B.V. & Co. KG Pseudotyped retroviral vector particle with anti-cd3 display
WO2024238153A1 (en) * 2023-05-15 2024-11-21 Umoja Biopharma, Inc. Lentiviral delivery of anti-cd20 chimeric antigen receptors
WO2024238769A2 (en) * 2023-05-16 2024-11-21 The Regents Of The University Of California Inhibitory chimeric antigen receptors that reduce car-t cell "on-target, off-tumor" toxicity
WO2025078492A1 (en) 2023-10-13 2025-04-17 Miltenyi Biotec B.V. & Co. KG Cd3-targeted nipah-pseudotyped lentiviral vector particles
WO2025162379A1 (zh) * 2024-02-01 2025-08-07 深圳市济因生物科技有限公司 一种多肽及包含所述多肽基因的病毒载体

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