CN112004543A - 包含细菌菌株的组合物 - Google Patents

包含细菌菌株的组合物 Download PDF

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Publication number
CN112004543A
CN112004543A CN201980026687.7A CN201980026687A CN112004543A CN 112004543 A CN112004543 A CN 112004543A CN 201980026687 A CN201980026687 A CN 201980026687A CN 112004543 A CN112004543 A CN 112004543A
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CN
China
Prior art keywords
present
cells
compositions
seq
composition
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Pending
Application number
CN201980026687.7A
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English (en)
Chinese (zh)
Inventor
多梅尼科·潘兹卡
艾米·贝丝·霍尔特
苏阿德·艾哈迈德
安娜·埃托尔
伊姆克·伊丽莎白·马尔德
菲利普·科威
艾玛·拉夫缇斯
艾玛·伊丽莎白·克莱尔·汉尼斯
黛尔芬·路易丝·克劳黛特·劳特卡里
奥雷利·帕斯卡·帕特里夏·库蒂里耶梅拉德
玛格丽特·英克斯特·黛尔德
马西里奥·阿德里亚尼
玛丽亚·克里斯托弗
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4D Pharma Research Ltd
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4D Pharma Research Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1804384.4A external-priority patent/GB201804384D0/en
Priority claimed from GBGB1809953.1A external-priority patent/GB201809953D0/en
Priority claimed from GBGB1811900.8A external-priority patent/GB201811900D0/en
Priority claimed from GBGB1812378.6A external-priority patent/GB201812378D0/en
Priority claimed from GBGB1813444.5A external-priority patent/GB201813444D0/en
Priority claimed from GBGB1813423.9A external-priority patent/GB201813423D0/en
Priority claimed from GBGB1816834.4A external-priority patent/GB201816834D0/en
Priority claimed from GBGB1817641.2A external-priority patent/GB201817641D0/en
Priority claimed from GBGB1901218.6A external-priority patent/GB201901218D0/en
Priority claimed from GBGB1901199.8A external-priority patent/GB201901199D0/en
Priority claimed from GBGB1901992.6A external-priority patent/GB201901992D0/en
Priority claimed from GBGB1901993.4A external-priority patent/GB201901993D0/en
Application filed by 4D Pharma Research Ltd filed Critical 4D Pharma Research Ltd
Publication of CN112004543A publication Critical patent/CN112004543A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55588—Adjuvants of undefined constitution
    • A61K2039/55594—Adjuvants of undefined constitution from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/46—Streptococcus ; Enterococcus; Lactococcus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
CN201980026687.7A 2018-03-19 2019-03-19 包含细菌菌株的组合物 Pending CN112004543A (zh)

Applications Claiming Priority (27)

Application Number Priority Date Filing Date Title
GBGB1804384.4A GB201804384D0 (en) 2018-03-19 2018-03-19 Compositions
GB1804384.4 2018-03-19
EP18178350.7 2018-06-18
GBGB1809953.1A GB201809953D0 (en) 2018-06-18 2018-06-18 Compositions
GB1809953.1 2018-06-18
EP18178350 2018-06-18
GB1811900.8 2018-07-20
GBGB1811900.8A GB201811900D0 (en) 2018-07-20 2018-07-20 Compositions comprising bacterial strains
GB1812378.6 2018-07-30
GBGB1812378.6A GB201812378D0 (en) 2018-07-30 2018-07-30 Compositions comprising bacterial strains
GB1813423.9 2018-08-17
GB1813444.5 2018-08-17
GBGB1813444.5A GB201813444D0 (en) 2018-08-17 2018-08-17 Compositions
GBGB1813423.9A GB201813423D0 (en) 2018-08-17 2018-08-17 Compositions comprising bacterial strains
GB1816834.4 2018-10-16
GBGB1816834.4A GB201816834D0 (en) 2018-10-16 2018-10-16 Compositions
GBGB1817641.2A GB201817641D0 (en) 2018-10-29 2018-10-29 Compositions comprising bacterial strains
GB1817641.2 2018-10-29
GBGB1901218.6A GB201901218D0 (en) 2019-01-29 2019-01-29 Compositions
GBGB1901199.8A GB201901199D0 (en) 2019-01-29 2019-01-29 Compositions comprising bacterial strains
GB1901218.6 2019-01-29
GB1901199.8 2019-01-29
GB1901993.4 2019-02-13
GBGB1901992.6A GB201901992D0 (en) 2019-02-13 2019-02-13 Compositions comprising bacterial strains
GB1901992.6 2019-02-13
GBGB1901993.4A GB201901993D0 (en) 2019-02-13 2019-02-13 Compositions
PCT/EP2019/056894 WO2019180051A1 (en) 2018-03-19 2019-03-19 Compositions comprising bacterial strains

Publications (1)

Publication Number Publication Date
CN112004543A true CN112004543A (zh) 2020-11-27

Family

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CN201980026687.7A Pending CN112004543A (zh) 2018-03-19 2019-03-19 包含细菌菌株的组合物
CN201980020532.2A Pending CN111886018A (zh) 2018-03-19 2019-03-19 组合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201980020532.2A Pending CN111886018A (zh) 2018-03-19 2019-03-19 组合物

Country Status (25)

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US (3) US11419931B2 (https=)
EP (3) EP3768284B1 (https=)
JP (3) JP2021518414A (https=)
KR (2) KR20210003096A (https=)
CN (2) CN112004543A (https=)
AU (2) AU2019238358A1 (https=)
BR (2) BR112020019008A2 (https=)
CA (2) CA3094297A1 (https=)
CY (1) CY1125104T1 (https=)
DK (1) DK3768284T3 (https=)
ES (1) ES2908826T3 (https=)
HR (1) HRP20220368T1 (https=)
HU (1) HUE058151T2 (https=)
IL (2) IL277422A (https=)
LT (1) LT3768284T (https=)
MA (1) MA52128A (https=)
MD (1) MD3768284T2 (https=)
MX (2) MX2020009736A (https=)
PL (1) PL3768284T3 (https=)
RS (1) RS63090B1 (https=)
SG (2) SG11202009254YA (https=)
SI (1) SI3768284T1 (https=)
SM (1) SMT202200111T1 (https=)
TW (2) TW202003001A (https=)
WO (2) WO2019180051A1 (https=)

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WO2019180051A1 (en) 2018-03-19 2019-09-26 4D Pharma Research Limited Compositions comprising bacterial strains
US20230022045A1 (en) * 2019-12-03 2023-01-26 Board Of Regents, The University Of Texas System Combination therapies for the treatment of cancer
EP4161541A4 (en) * 2020-06-09 2024-09-11 Flagship Pioneering Innovations VI, LLC PHYSIOLOGICALLY ACCEPTABLE COMPOSITIONS CONTAINING MICROORGANISMS OR MICROBIAL PRODUCTS
US12350300B2 (en) 2021-10-08 2025-07-08 Iowa State University Research Foundation, Inc. Use of dopamine producing products to increase vaccine efficacy
CN113999923B (zh) * 2021-11-25 2024-05-14 上海金翌生物科技有限公司 小柳-原田综合症标志微生物及其应用
CN115287243B (zh) * 2022-04-15 2023-06-06 集美大学 一株变形假单胞菌flgK基因沉默菌株及其构建方法
JPWO2024096122A1 (https=) * 2022-11-04 2024-05-10
KR102878250B1 (ko) 2023-01-11 2025-10-31 서울대학교산학협력단 코리스메이트 뮤테이즈 단백질 또는 이를 암호화하는 폴리뉴클레오티드를 포함하는 암 예방 또는 치료용 조성물

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SMT202200111T1 (it) 2022-05-12
US11857614B2 (en) 2024-01-02
JP2021518129A (ja) 2021-08-02
KR20210003096A (ko) 2021-01-11
CA3094297A1 (en) 2019-09-26
DK3768284T3 (da) 2022-03-07
HRP20220368T1 (hr) 2022-06-24
CA3094139A1 (en) 2019-09-26
KR20200134255A (ko) 2020-12-01
US20210169950A1 (en) 2021-06-10
IL277421A (en) 2020-11-30
US20220257745A1 (en) 2022-08-18
BR112020018818A2 (pt) 2021-05-04
WO2019180051A1 (en) 2019-09-26
BR112020019008A2 (pt) 2020-12-29
WO2019180000A1 (en) 2019-09-26
AU2019239048B2 (en) 2022-07-21
PL3768284T3 (pl) 2022-04-11
JP2021518414A (ja) 2021-08-02
SG11202009254YA (en) 2020-10-29
SI3768284T1 (sl) 2022-04-29
EP3768284A1 (en) 2021-01-27
TW202003000A (zh) 2020-01-16
MX2020009733A (es) 2022-10-27
TW202003001A (zh) 2020-01-16
SG11202009259VA (en) 2020-10-29
JP2023100747A (ja) 2023-07-19
IL277422A (en) 2020-11-30
EP3768285A1 (en) 2021-01-27
EP3768284B1 (en) 2022-01-05
EP4046644A1 (en) 2022-08-24
ES2908826T3 (es) 2022-05-04
RS63090B1 (sr) 2022-04-29
IL277421B (en) 2022-04-01
MA52128A (fr) 2021-01-27
HUE058151T2 (hu) 2022-07-28
AU2019238358A1 (en) 2020-10-08
CY1125104T1 (el) 2024-02-16
LT3768284T (lt) 2022-04-11
AU2019239048A1 (en) 2020-11-05
KR102578117B1 (ko) 2023-09-12
MX2020009736A (es) 2021-01-08
US11419931B2 (en) 2022-08-23
CN111886018A (zh) 2020-11-03
MD3768284T2 (ro) 2022-06-30
US20210138058A1 (en) 2021-05-13

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