CN1117731A - 具有抑制精神病活性的芳香杂环化合物 - Google Patents
具有抑制精神病活性的芳香杂环化合物 Download PDFInfo
- Publication number
- CN1117731A CN1117731A CN94191142A CN94191142A CN1117731A CN 1117731 A CN1117731 A CN 1117731A CN 94191142 A CN94191142 A CN 94191142A CN 94191142 A CN94191142 A CN 94191142A CN 1117731 A CN1117731 A CN 1117731A
- Authority
- CN
- China
- Prior art keywords
- compound
- benzisothiazole
- butyl
- piperazinyl
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939302622A GB9302622D0 (en) | 1993-02-10 | 1993-02-10 | Heteroaromatic compounds |
| GB9302622.7 | 1993-02-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1117731A true CN1117731A (zh) | 1996-02-28 |
Family
ID=10730183
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN94191142A Pending CN1117731A (zh) | 1993-02-10 | 1994-02-10 | 具有抑制精神病活性的芳香杂环化合物 |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0683778A1 (hu) |
| JP (1) | JPH08506337A (hu) |
| CN (1) | CN1117731A (hu) |
| AU (1) | AU6005194A (hu) |
| BG (1) | BG99839A (hu) |
| CA (1) | CA2155758A1 (hu) |
| CZ (1) | CZ204495A3 (hu) |
| FI (1) | FI953777A0 (hu) |
| GB (1) | GB9302622D0 (hu) |
| HU (1) | HUT73654A (hu) |
| IL (1) | IL108601A0 (hu) |
| MX (1) | MX9401080A (hu) |
| SK (1) | SK99195A3 (hu) |
| WO (1) | WO1994018196A1 (hu) |
| ZA (1) | ZA94891B (hu) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5364866A (en) | 1989-05-19 | 1994-11-15 | Hoechst-Roussel Pharmaceuticals, Inc. | Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics |
| US5776963A (en) | 1989-05-19 | 1998-07-07 | Hoechst Marion Roussel, Inc. | 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility |
| GB9420521D0 (en) * | 1994-10-12 | 1994-11-30 | Smithkline Beecham Plc | Novel compounds |
| JP3274579B2 (ja) * | 1995-01-12 | 2002-04-15 | 住友製薬株式会社 | 脳血管障害に伴う精神症候治療剤 |
| DK0732332T3 (da) * | 1995-03-17 | 2002-04-15 | Aventis Pharma Inc | Substituerede benzothienylpiperaziner, deres anvendelse som lægemidler og fremgangsmåder til fremstilling deraf |
| UA73981C2 (en) | 2000-03-10 | 2005-10-17 | Merck Patent Gmbh | (r)-(-)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane for treatment of extrapyramidal movement disorders (variants), pharmaceutical composition and kit |
| RU2283648C2 (ru) * | 2000-11-14 | 2006-09-20 | Мерк Патент Гмбх | Новое применение комбинированных селективных антагонистов допаминового рецептора d2 и агонистов рецептора 5-нт 1a |
| JP4497815B2 (ja) * | 2001-02-16 | 2010-07-07 | アベンティス・ファーマスーティカルズ・インコーポレイテツド | 新規な複素環式アミド誘導体およびドーパミンｄ３受容体リガンドとしてのその使用 |
| SI1408964T1 (sl) | 2001-07-26 | 2007-06-30 | Merck Patent Gmbh | Uporaba 2- 5-(4-fluorofenil)-3-piridilmetil-aminometil -kromana in njegovih fizioloĺ ko sprejemljivih soli |
| GB0222912D0 (en) | 2002-10-03 | 2002-11-13 | Astrazeneca Ab | Novel process and intermediates |
| GB0222909D0 (en) * | 2002-10-03 | 2002-11-13 | Astrazeneca Ab | Novel process and intermediates |
| ZA200700527B (en) * | 2004-07-20 | 2008-08-27 | Siena Biotech Spa | Modulators of alpha7 nicotinic acetylcholine receptors and therapeutic uses thereof |
| CL2008000119A1 (es) | 2007-01-16 | 2008-05-16 | Wyeth Corp | Compuestos derivados de pirazol, antagonistas del receptor nicotinico de acetilcolina; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como demencia senil, alzheimer y esquizofrenia. |
| EP2736905A4 (en) * | 2011-07-28 | 2015-07-29 | Mapi Pharma Ltd | INTERMEDIATE COMPOUNDS AND PROCESS FOR THE PREPARATION OF LURASIDONE AND SALTS THEREOF |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0625181B2 (ja) * | 1985-03-27 | 1994-04-06 | 住友製薬株式会社 | 新規なイミド誘導体 |
| AU593194B2 (en) * | 1986-09-26 | 1990-02-01 | Sumitomo Pharmaceuticals Company, Limited | Imide derivatives ,and their production and use |
| US5143923B1 (en) * | 1991-04-29 | 1993-11-02 | Hoechst-Roussel Pharmaceuticals Incorporated | Benzoisothiazole-and benzisoxazole-3-carboxamides |
| IL101722A (en) * | 1991-05-02 | 1996-05-14 | Wyeth John & Brother Ltd | History of piperazine, their preparation and pharmaceutical preparations containing them |
-
1993
- 1993-02-10 GB GB939302622A patent/GB9302622D0/en active Pending
-
1994
- 1994-02-09 ZA ZA94891A patent/ZA94891B/xx unknown
- 1994-02-09 IL IL10860194A patent/IL108601A0/xx unknown
- 1994-02-10 AU AU60051/94A patent/AU6005194A/en not_active Abandoned
- 1994-02-10 JP JP6517819A patent/JPH08506337A/ja active Pending
- 1994-02-10 HU HU9501881A patent/HUT73654A/hu unknown
- 1994-02-10 WO PCT/GB1994/000265 patent/WO1994018196A1/en not_active Application Discontinuation
- 1994-02-10 SK SK991-95A patent/SK99195A3/sk unknown
- 1994-02-10 EP EP94906290A patent/EP0683778A1/en not_active Withdrawn
- 1994-02-10 CN CN94191142A patent/CN1117731A/zh active Pending
- 1994-02-10 CA CA002155758A patent/CA2155758A1/en not_active Abandoned
- 1994-02-10 MX MX9401080A patent/MX9401080A/es unknown
- 1994-02-10 CZ CZ952044A patent/CZ204495A3/cs unknown
-
1995
- 1995-08-02 BG BG99839A patent/BG99839A/bg unknown
- 1995-08-09 FI FI953777A patent/FI953777A0/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU6005194A (en) | 1994-08-29 |
| CA2155758A1 (en) | 1994-08-18 |
| HU9501881D0 (en) | 1995-08-28 |
| EP0683778A1 (en) | 1995-11-29 |
| MX9401080A (es) | 1994-08-31 |
| IL108601A0 (en) | 1994-05-30 |
| CZ204495A3 (en) | 1996-03-13 |
| WO1994018196A1 (en) | 1994-08-18 |
| JPH08506337A (ja) | 1996-07-09 |
| HUT73654A (en) | 1996-09-30 |
| GB9302622D0 (en) | 1993-03-24 |
| FI953777A (fi) | 1995-08-09 |
| SK99195A3 (en) | 1995-12-06 |
| ZA94891B (en) | 1995-08-10 |
| BG99839A (bg) | 1996-02-28 |
| FI953777A0 (fi) | 1995-08-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |