CN111386263A - 调节嵌合抗原受体 - Google Patents

调节嵌合抗原受体 Download PDF

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Publication number
CN111386263A
CN111386263A CN201880024542.9A CN201880024542A CN111386263A CN 111386263 A CN111386263 A CN 111386263A CN 201880024542 A CN201880024542 A CN 201880024542A CN 111386263 A CN111386263 A CN 111386263A
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dtag
immune effector
amino acid
cells
car
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CN201880024542.9A
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Chinese (zh)
Inventor
J·布拉德纳
J·罗伯茨
B·纳贝特
G·温特
A·J·菲利普斯
T·P·赫弗南
D·巴克利
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Dana Farber Cancer Institute Inc
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Dana Farber Cancer Institute Inc
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CN201880024542.9A 2017-02-08 2018-02-08 调节嵌合抗原受体 Pending CN111386263A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762456649P 2017-02-08 2017-02-08
US62/456,649 2017-02-08
US201762457124P 2017-02-09 2017-02-09
US62/457,124 2017-02-09
PCT/US2018/017464 WO2018148440A1 (en) 2017-02-08 2018-02-08 Regulating chimeric antigen receptors

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CN111386263A true CN111386263A (zh) 2020-07-07

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US (1) US11311609B2 (https=)
EP (2) EP3580212A4 (https=)
JP (1) JP7227912B2 (https=)
CN (1) CN111386263A (https=)
AU (1) AU2018219289A1 (https=)
CA (1) CA3053006C (https=)
WO (1) WO2018148440A1 (https=)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112194726A (zh) * 2020-09-02 2021-01-08 沣潮医药科技(上海)有限公司 用于病理性蛋白聚集物清除的嵌合抗原受体及其应用
CN112321713A (zh) * 2020-12-31 2021-02-05 北京艺妙神州医药科技有限公司 一种抗bcma的抗体及其应用
CN113234162A (zh) * 2020-12-24 2021-08-10 四川大学华西医院 一种靶向cd133的嵌合抗原受体t细胞
CN114874132A (zh) * 2022-05-24 2022-08-09 无锡捷化医药科技有限公司 一种重组人受体蛋白fkbp12配体的制备方法
CN115677667A (zh) * 2021-07-30 2023-02-03 海创药业股份有限公司 一种双功能嵌合体杂环化合物及其作为雄激素受体降解剂的用途
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CN116323570A (zh) * 2020-09-30 2023-06-23 上海睿跃生物科技有限公司 治疗疾病的化合物和方法
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CN112194726B (zh) * 2020-09-02 2023-06-23 沣潮医药科技(上海)有限公司 用于病理性蛋白聚集物清除的嵌合抗原受体及其应用
CN116323570A (zh) * 2020-09-30 2023-06-23 上海睿跃生物科技有限公司 治疗疾病的化合物和方法
CN116615429B (zh) * 2020-10-14 2026-02-27 珃诺生物医药科技(杭州)有限公司 用于靶向蛋白降解的方法和组合物
CN116615429A (zh) * 2020-10-14 2023-08-18 珃诺生物医药科技(杭州)有限公司 用于靶向蛋白降解的方法和组合物
CN113234162A (zh) * 2020-12-24 2021-08-10 四川大学华西医院 一种靶向cd133的嵌合抗原受体t细胞
CN112321713A (zh) * 2020-12-31 2021-02-05 北京艺妙神州医药科技有限公司 一种抗bcma的抗体及其应用
CN115677667B (zh) * 2021-07-30 2024-11-15 海创药业股份有限公司 一种双功能嵌合体杂环化合物及其作为雄激素受体降解剂的用途
CN115677667A (zh) * 2021-07-30 2023-02-03 海创药业股份有限公司 一种双功能嵌合体杂环化合物及其作为雄激素受体降解剂的用途
WO2023070527A1 (zh) * 2021-10-29 2023-05-04 上海鑫湾生物科技有限公司 一种条件控制的可剪接嵌合抗原受体分子及其应用
CN114874132A (zh) * 2022-05-24 2022-08-09 无锡捷化医药科技有限公司 一种重组人受体蛋白fkbp12配体的制备方法
CN114874132B (zh) * 2022-05-24 2023-06-06 无锡捷化医药科技有限公司 一种重组人受体蛋白fkbp12配体的制备方法
CN119410598A (zh) * 2024-09-27 2025-02-11 武汉大学 一种靶标识别系统及其应用

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