CN110785180B - 溶瘤病毒疗法和免疫疗法 - Google Patents
溶瘤病毒疗法和免疫疗法 Download PDFInfo
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- CN110785180B CN110785180B CN201880042149.2A CN201880042149A CN110785180B CN 110785180 B CN110785180 B CN 110785180B CN 201880042149 A CN201880042149 A CN 201880042149A CN 110785180 B CN110785180 B CN 110785180B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
- A61K35/761—Adenovirus
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- A—HUMAN NECESSITIES
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- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
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- A—HUMAN NECESSITIES
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2319/00—Fusion polypeptide
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- Animal Behavior & Ethology (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762488181P | 2017-04-21 | 2017-04-21 | |
| US62/488,181 | 2017-04-21 | ||
| PCT/US2018/028577 WO2018195427A2 (en) | 2017-04-21 | 2018-04-20 | Oncolytic virotherapy and immunotherapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110785180A CN110785180A (zh) | 2020-02-11 |
| CN110785180B true CN110785180B (zh) | 2024-04-02 |
Family
ID=62196688
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201880042149.2A Active CN110785180B (zh) | 2017-04-21 | 2018-04-20 | 溶瘤病毒疗法和免疫疗法 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US11896634B2 (enExample) |
| EP (1) | EP3612202A2 (enExample) |
| JP (2) | JP7260173B2 (enExample) |
| KR (2) | KR102830905B1 (enExample) |
| CN (1) | CN110785180B (enExample) |
| AU (2) | AU2018254566B2 (enExample) |
| CA (1) | CA3060573A1 (enExample) |
| NZ (1) | NZ758626A (enExample) |
| SG (1) | SG11201909749PA (enExample) |
| TW (1) | TWI799411B (enExample) |
| WO (1) | WO2018195427A2 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6576326B2 (ja) | 2013-03-14 | 2019-09-18 | ソーク インスティテュート フォー バイオロジカル スタディーズ | 腫瘍溶解性アデノウイルス組成物 |
| GB201500319D0 (en) * | 2015-01-09 | 2015-02-25 | Agency Science Tech & Res | Anti-PD-L1 antibodies |
| KR20220163505A (ko) | 2016-02-23 | 2022-12-09 | 솔크 인스티튜트 포 바이올로지칼 스터디즈 | 바이러스 동역학에 미치는 영향 최소화를 위한 치료용 아데노바이러스의 외인성 유전자 발현 |
| JP7054527B2 (ja) | 2016-02-23 | 2022-04-14 | ソーク インスティテュート フォー バイオロジカル スタディーズ | アデノウイルスの複製動態を測定するための高スループットアッセイ |
| JP2019536468A (ja) | 2016-12-12 | 2019-12-19 | ソーク インスティテュート フォー バイオロジカル スタディーズ | 腫瘍を標的にする合成アデノウイルスおよびその使用 |
| SG11201909749PA (en) * | 2017-04-21 | 2019-11-28 | Baylor College Medicine | Oncolytic virotherapy and immunotherapy |
| SG10201801219VA (en) * | 2018-02-13 | 2019-09-27 | Agency Science Tech & Res | Anti-HER2 Antibodies |
| AU2019251356B2 (en) | 2018-04-09 | 2025-06-12 | Salk Institute For Biological Studies | Oncolytic adenovirus compositions with enhanced replication properties |
| WO2019202118A1 (en) * | 2018-04-20 | 2019-10-24 | Baylor College Of Medicine | Oncolytic virotherapy and immunotherapy |
| US11413315B2 (en) * | 2018-04-29 | 2022-08-16 | City Of Hope | Neural stem cell-mediated cancer treatment |
| TWI856035B (zh) * | 2018-10-25 | 2024-09-21 | 貝勒醫學院 | 溶瘤病毒療法及免疫療法 |
| US11407828B2 (en) | 2019-02-01 | 2022-08-09 | Novarock Biotherapeutics, Ltd. | Anti-CLauDiN 18 antibodies and methods of use thereof |
| CN111743923B (zh) * | 2019-03-27 | 2024-11-08 | 北京康万达医药科技有限公司 | 包含分离的重组溶瘤腺病毒和免疫细胞的治疗剂及其应用 |
| CA3138527C (en) * | 2019-04-29 | 2024-03-12 | Mayo Foundation For Medical Education And Research | Multivalent pd-l1 binding compounds for treating cancer |
| WO2021091560A1 (en) * | 2019-11-07 | 2021-05-14 | Baylor College Of Medicine | Oncolytic virotherapy and immunotherapy |
| CN111632146B (zh) * | 2020-05-29 | 2021-09-28 | 中山大学 | Oat抑制剂和溶瘤病毒在制备抗肿瘤药物中的应用 |
| CN111676245B (zh) * | 2020-06-24 | 2022-09-13 | 武汉波睿达生物科技有限公司 | 一种含有HSV-1型溶瘤病毒的NFAT-Cre-CAR-T细胞及其应用 |
| WO2022007804A1 (zh) * | 2020-07-07 | 2022-01-13 | 深圳市菲鹏生物治疗股份有限公司 | T淋巴细胞及其应用 |
| CN113425856B (zh) * | 2021-07-07 | 2022-01-04 | 浙江康佰裕生物科技有限公司 | 一种含有基因修饰的溶瘤病毒的药物组合物及其在治疗癌症的用途 |
| WO2023076469A1 (en) * | 2021-10-29 | 2023-05-04 | Unm Rainforest Innovations | Oncolytic virotherapy compositions and methods |
| CN114032323B (zh) * | 2021-11-17 | 2023-08-08 | 云南省烟草农业科学研究院 | 一种与雪茄烟抗黑胫病基因紧密连锁的共显性ssr标记及其应用 |
| WO2024042231A1 (en) * | 2022-08-26 | 2024-02-29 | Universite De Namur | Adenovirus-based adjuvants for cancer treatment |
| WO2024229083A1 (en) * | 2023-05-03 | 2024-11-07 | Mayo Foundation For Medical Education And Research | Methods and materials for treating cancer |
| CN118930652B (zh) * | 2024-07-29 | 2025-03-11 | 北京肿瘤医院(北京大学肿瘤医院) | 一种免疫检查点pd-l2靶向单链抗体及放射性核素标记物与应用 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005086922A2 (en) * | 2004-03-10 | 2005-09-22 | Board Of Regents, University Of Texas System | Oncolytic adenovirus armed with therapeutic genes |
| CN106831986A (zh) * | 2015-12-04 | 2017-06-13 | 浙江大学 | 一种抗人her2抗体及其编码基因和应用 |
| CN106831987A (zh) * | 2015-12-04 | 2017-06-13 | 浙江大学 | 一种抗人her2抗体及其编码基因和应用 |
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| CN106831986A (zh) * | 2015-12-04 | 2017-06-13 | 浙江大学 | 一种抗人her2抗体及其编码基因和应用 |
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| TW201903154A (zh) | 2019-01-16 |
| CA3060573A1 (en) | 2018-10-25 |
| TWI799411B (zh) | 2023-04-21 |
| CN110785180A (zh) | 2020-02-11 |
| JP7620994B2 (ja) | 2025-01-24 |
| SG11201909749PA (en) | 2019-11-28 |
| KR20240093758A (ko) | 2024-06-24 |
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| JP2020517635A (ja) | 2020-06-18 |
| US10716818B2 (en) | 2020-07-21 |
| AU2018254566A1 (en) | 2019-11-21 |
| US20200323932A1 (en) | 2020-10-15 |
| US20190374589A1 (en) | 2019-12-12 |
| EP3612202A2 (en) | 2020-02-26 |
| AU2025203355A1 (en) | 2025-06-19 |
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