CN110384650A - It is a kind of for skin moisture-keeping, the probiotic composition of barrier protection and its application in cosmetics - Google Patents
It is a kind of for skin moisture-keeping, the probiotic composition of barrier protection and its application in cosmetics Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
Abstract
The invention discloses a kind of for skin moisture-keeping, the probiotic composition of barrier protection and its application in cosmetics.This is for skin moisture-keeping, the composition of barrier protection probiotics; be based on the total weight of the composition, include component: saccharomycete/1-40 parts of rice fermentation product, 1-30 parts of lactic acid bacteria lysate; two split 1-30 parts of lysis object of saccharomycetes to make fermentation product, 1-30 parts of thermus thermophilus tunning.The probiotic composition has effects that stronger moisturizing and repairs skin barrier, effectively pernicious bacteria can be inhibited to survive, prevent skin infection, body self-healing immunity can be assisted to get well with rapid recovery skin problem.
Description
Technical field
The present invention relates to a kind of probiotic composition and its applications, belong to cosmetic technical field, more particularly, to one kind
For skin moisture-keeping, the probiotic composition of barrier protection and its application in cosmetics.
Background technique
Everyone skin surface has one layer of natural skin barrier, it is by human epidermal cuticula and sebum film structure
At.Cuticula is the outermost layer of skin, due to day contained in the hydrophilic of cuticula itself, barrier function and cuticula
The effects of right moisturizing factor, that is, amino acids, lactate and carbohydrate, so that cuticula usually contains 10~30% moisture, it is this
Environment becomes the cradle of skin itself microbe colony growth.But with advancing age, the water content of cuticula can be gradually
It reduces, when moisture content is lower than 10%, the various problems of skin will be caused.
Skin is at every moment all contacted with the external world, cuticula constantly by the challenge of external environment, as temperature, humidity,
Pathogen, pollution and solar UV etc..If not being protected, cuticula just will appear water shortage, skin itself microbial bacteria
The growing environment of group is destroyed, and Microflora is reduced, and then the impaired various problems of barrier occurs.Therefore, it is necessary to both have
Moisture-keeping function can play the product of barrier protection again, just necessary in cosmetic applications.
And probiotics technology can solve these problems, probiotics on cosmetics, can balance skin epidermis flora,
Repair skin barrier.As reported in the literature, probiotics external application can treat atopic dermatitis, that is inhibit other bacteriums
Proliferation, so that the microbial flora of skin surface is reached balance.Meanwhile probiotics external application also can be reduced the release of inflammatory mediator,
Promote the reparation of skin barrier.
Therefore, it as can a variety of prebiotic fungus extracts are combined to form probiotic composition, and is applied in skin care item,
There will be multiple protective skin barrier.But not yet occur cosmetics effectively containing probiotic composition at present,
Even if having, effect is also monistic, it is difficult to meet the multi-efficiencies such as whitening, moisturizing, anti-aging.
Summary of the invention
The purpose of the present invention is to provide a kind of for skin moisture-keeping, the probiotic composition of barrier protection, have compared with
The effect of strong moisturizing and reparation skin barrier, effectively pernicious bacteria can be inhibited to survive, prevent skin infection, it can also be quickly
Alleviate skin problem, body self-healing immunity is assisted to get well.
It is a further object of the present invention to provide a kind of with above-mentioned for skin moisture-keeping, the composition of barrier protection probiotics
Application in cosmetics enables cosmetics to give full play to the multiple skin-care effect such as whitening, moisturizing, anti-aging.
Of the existing technology in order to solve the problems, such as, present invention employs the following technical solutions:
It is a kind of to be based on the total weight of the composition for skin moisture-keeping, the probiotic composition of barrier protection, the probiotics
Composition includes following components:
Saccharomycete/1-40 parts of rice fermentation product；1-30 parts of lactic acid bacteria lysate, two split saccharomycetes to make fermentation product lysis
1-30 parts of object；1-30 parts of thermus thermophilus tunning.
Furthermore, it is based on the total weight of the composition, the probiotic composition includes following components:
Saccharomycete/15-40 parts of rice fermentation product；15-30 parts of lactic acid bacteria lysate, two to split saccharomycetes to make fermentation product molten
15-30 parts of born of the same parents' object；15-30 parts of thermus thermophilus tunning.
Furthermore, the saccharomycete/rice fermentation product is rice fermentation product of the rice after saccharomycetes to make fermentation
Filtrate.
Furthermore, the saccharomycete is brewer's yeast, saccharomyces uvarum, Hansenula yeast, torulopsis, false silk ferment
The one such or several composition of mother, pichia, rhodotorula；Its volume ratio is 1:1-3:1-4:1-5, and concentration is
105-108CFU/ml。
Furthermore, the lactic acid bacteria is lactobacillus bulgaricus, cheese lactic acid bacteria, lactobacillus acidophilus, thermophilus
Bacterium, lactobacillus plantarum, the one such or several composition of Lactobacillus rhamnosus.
Furthermore, the saccharomycete/rice fermentation product bacterium colony concentration is 106-108CFU/ml, preferred concentration are
107-108CFU/ml, more preferably 108CFU/ml；The bacterium colony concentration of the lactic acid bacteria lysate is 106-108CFU/ml, it is excellent
Selecting concentration is 106-107CFU/ml, more preferably 107CFU/ml；Described two split the bacterium colony concentration of saccharomycetes to make fermentation product lysis object
It is 106-108CFU/ml, preferred concentration 106-107CFU/ml, more preferably 107CFU/ml；The thermus thermophilus fermentation produces
The bacterium colony concentration of object is 106-108CFU/ml, preferred concentration 107-108CFU/ml, more preferably 108CFU/ml；Between four
Weight ratio be 1:1-5:1-5:1-5, wherein be preferably in a proportion of 1:2-4:2-4:2-4, most ratio of greater inequality is 1:2:3:4.
In addition, the present invention also provides a kind of above-mentioned probiotic composition for being used for skin moisture-keeping, barrier protection, including it is following
Step:
Respectively by saccharomycete/1-40 parts of rice fermentation product；1-30 parts of lactic acid bacteria lysate, two split saccharomycetes to make fermentation production
1-30 parts of object lysis object；1-30 parts of thermus thermophilus tunning are mixed, and be added to any required skin moisture-keeping,
In the cosmetics of barrier protection.
In addition, the application the present invention also provides a kind of above-mentioned probiotic composition in cosmetics, the cosmetics contain
There is the probiotic composition of 5~10wt%；And the customary adjuvant of 90~99wt%.
Furthermore, the customary adjuvant includes surfactant, thickener, conditioner, moisturizer, preservative, chela
Mixture, essence, one of deionized water or a variety of；The cosmetics are face cream, facial mask, Essence, toner, lotion or wash
Face milk.
By above-mentioned technical proposal, the beneficial effects of the present invention are:
1) present invention employs advanced probiotics fermention and combination techniques, greatly ensure that probiotics fermention produces
The bioactivity of object is more advantageous to it and plays moisturizing and barrier protection effect.
2) probiotics fermention composition component of the invention include saccharomycete/rice fermentation product, lactic acid bacteria lysate,
Two split saccharomycetes to make fermentation product lysis object, thermus thermophilus tunning, wherein lactic acid bacteria lysate have it is antibacterial, repair,
The effect of antiallergic, moisturizing, and two split saccharomycetes to make fermentation product lysis object with very strong anti-immunity inhibitory activity and can promote DNA
It repairs, prevents the light aging of epidermis and corium, can effectively protect skin, therefore the composition that probiotics technology of the invention obtains
Have effects that dual skin ensures and stronger moisture-keeping efficacy.
Detailed description of the invention
Fig. 1 be shown using after the present composition through transepidermal water loss amount variation diagram；
Fig. 2 is shown using cuticula change of moisture content figure after the present composition.
Specific embodiment
Below by way of specific preferred embodiment combination attached drawing, invention is further described in detail, but the present invention and not only
It is limited to embodiment below.
The invention discloses a kind of preparation method and applications for skin moisture-keeping, the probiotic composition of barrier protection.
This is based on the total weight of the composition for skin moisture-keeping, the composition of barrier protection probiotics, includes following raw material components:
Saccharomycete/1-40 parts of rice fermentation product, 1-30 parts of lactic acid bacteria lysate, two split saccharomycetes to make fermentation product lysis
1-30 parts of object, 1-30 parts of thermus thermophilus tunning.
Wherein, important source material of the invention is described below:
1. saccharomycete/rice fermentation product
For rice in the saccharomycete/rice fermentation product from Japanese autumn fields rice, such rice is grown in autumn fields
County is located at Japanese Honshu island northeast, and one year cyclic vibration is up to 40 DEG C or more the temperature difference, 1600 hours accumulated temperature, and 50 is public around planting area
In it is pollution-free, using drinkable 3A water quality Natural Water irrigate, contained vitamin and mineral matter element are significantly larger than general rice.Institute
It is one such or several for saccharomyces uvarum, torulopsis, Candida, pichia to state saccharomycete, volume ratio is
1:1-3:1-4:1-5, concentration 105-108CFU/ml。
The saccharomycete/rice fermentation product has the moisture-retaining capacity for improving skin, prevents from having dry skin, and remolds skin water
Profit and other effects.
2. lactic acid bacteria lysate
Lactic acid bacteria in the lactic acid bacteria lysate is lactobacillus bulgaricus, cheese lactic acid bacteria, and lactobacillus acidophilus is thermophilic
Hot streptococcus, lactobacillus plantarum, Lactobacillus rhamnosus is one such or several, and its ratio be 0.5-2:1-3:1-4:1-5:2-
5:1-3, bacterium colony concentration are 106-108CFU/g.The lactic acid bacteria lysate has antiallergic anti-aging function.
3. two split saccharomycetes to make fermentation product lysis object
Described two to split yeast lysate be the physiology lysate obtained from Bifidobacterium by biotechnology, can be led to
Enhancing endogenous cellular enzymatic education complex system is crossed to prevent damage caused by ultraviolet light, is provided for normal skin and ripe age skin
Prevention nursing.
4. thermus thermophilus tunning
The thermus thermophilus tunning is the physiology lysis obtained from thermus thermophilus by biofermentation technique
Product can generate the superoxide dismutase (SOD) and vitamin B of thermal stability, have and delay senescence, and it is anti-to mitigate scytitis
It answers, resists the damage of daylight, cytothesis is promoted to keep the health of skin.Thermophilic heat of dwelling in the thermophilic hot fermentation product of dwelling
Bacterium is a kind of thermoduric bacteria, is purchased from American Type Culture Collection Center (ATCC), deposit number BAA-163.
The composition of the probiotics has effects that stronger moisturizing and repairs skin barrier, can effectively inhibit harmful bacteria
All living creatures deposits, and prevents skin infection, body self-healing immunity can be assisted to get well with rapid recovery skin problem.
The unit of following parts by weight can be g or kg.
Embodiment 1
It is a kind of for skin moisture-keeping, the probiotic composition of barrier protection, component includes:
Saccharomycete/35 parts of rice fermentation product, 20 parts of lactic acid bacteria lysate, two split saccharomycetes to make fermentation product lysis object 20
Part, 15 parts of thermus thermophilus tunning.
Wherein, saccharomycete/rice fermentation product, lactic acid bacteria lysate, two split saccharomycetes to make fermentation product lysis object, thermophilic
Thermus tunning, bacterium colony concentration C FU are 108/ ml, its ratio be 1:2:2:1.
Above-mentioned composition 5wt% is taken, adds the deionized water of 95wt%, mixes well, be applied to skin lesion sites.
Embodiment 2
It is a kind of for skin moisture-keeping, the probiotic composition of barrier protection, component includes:
Saccharomycete/40 parts of rice fermentation product, 15 parts of lactic acid bacteria lysate, two split saccharomycetes to make fermentation product lysis object 15
Part, 30 parts of thermus thermophilus tunning.
Wherein saccharomycete/rice fermentation product, lactic acid bacteria lysate, two split saccharomycetes to make fermentation product lysis object, thermophilic
Thermus tunning, bacterium colony concentration C FU are 108, its ratio be 2:1:1:2.
Above-mentioned composition 10wt% is taken, adds the deionized water of 90wt%, mixes well, be applied to skin lesion sites.
Embodiment 3
It is a kind of for skin moisture-keeping, the probiotic composition of barrier protection, component includes:
Saccharomycete/15 parts of rice fermentation product, 30 parts of lactic acid bacteria lysate, two split saccharomycetes to make fermentation product lysis object 30
Part, 25 parts of thermus thermophilus tunning.
Wherein, saccharomycete/rice fermentation product, lactic acid bacteria lysate, two split saccharomycetes to make fermentation product lysis object, thermophilic
Thermus tunning, bacterium colony concentration C FU are 108/ ml, its ratio be 1:2:1:2.
Above-mentioned composition 8wt% is taken, adds the deionized water of 92wt%, mixes well, be applied to skin lesion sites.
The following are the contents of effete test embodiment part.
Effete test embodiment 1
1, promote skin barrier function detection:
Sample made from Example 1-3 is as test sample.
Using obtained for skin moisture-keeping, the probiotic composition of barrier protection described in 10% embodiment 1-3, by its with
Lotion mixing, obtains the lotion containing the present composition, which is used for clinical trial.
Subject: 30 people of male, 90 people of women, the age 20-55 years old, average age (30.56 ± 14.44) year, wherein 10
Artificial excessively cleaning causes skin barrier impaired, and 24 people are that improper exfoliating causes skin barrier impaired, and 28 people are laser smoothing wrinkle
Operation causes skin barrier impaired, and 28 people are that the operation of laser nti-freckle causes skin barrier impaired, and 30 people are that the operation of laser anti-acne is led
Cause skin barrier impaired.All subjects, are randomly divided into treatment group and control group.
Experimental method:
Experimental group gives sample made from embodiment 1-3；Control group 1-2 does not smear any sample.Two groups of cleaning skin lesion portions
Behind position, using by test product.It is used 20 days using one-time continuous daily.
Safety evaluatio:
Clinical use examines in the process and the appearance that has no adverse reaction, and conscientiously records, and tracing study, if discovery patient
Have discomfort, should interrupt experiments immediately, and actively take measures.
Skin barrier function detection:
Using the moisture of skin tester (VapoMeter) of DELFIND company, Finland and through transepidermal water loss measuring instrument
(VapoMeterTEWL) water content of stratum corneum is detected and through epidermis fluid loss.It is measured under the conditions of constant temperature and humidity, room temperature 20
~25 DEG C, relative humidity is 40%~60%, and testee cleans skin to be measured before detection and 30 minutes in advance enter test
It is quiet to be measured in environment, the non-cutaneous lesion of cheek is detected respectively.
Statistical method:
Statistical analysis uses SPSS3.0 software, is examined using t and carries out statistical procedures.It is aobvious that P < 0.05 indicates that difference has
Work property.
Two groups of subjects skin's barrier function injury repair settings are compared, statistical result is as shown in table 1 below.
1 two groups of subjects skin's barrier function injury repair settings comparisons of table
As a result as table 1 and Fig. 1 using after the present composition through shown in transepidermal water loss amount variation diagram, skin after skin barrier is impaired
The transepidermal water loss amount of skin is higher, and the water content of cuticula is lower.After treatment, experimental group compared with the control group, subjects skin's screen
Barrier function obviously makes moderate progress, and two Testing index of experimental group are compared with two Testing index of control group after treatment, difference
With conspicuousness, P < 0.05.
Effete test embodiment 2
1, chronic skin moisture-keeping functions detect:
Using obtained for skin moisture-keeping, the probiotic composition of barrier protection described in 5% embodiment 1-3, by its with
Essence mixing, obtains the Essence containing the present composition, which is used for clinical trial.
1) experiment purpose:
Essence that 0.2% present invention mixes is studied to skin chronic skin moistening effect.
2) experimental method
Select 70 age brackets in volunteer's (moisture content of skin is less than 10%) of 30-50 years old dry skin, then will be upper
It states volunteer and is randomly divided into blank control group, control group and experimental group 1-5 group, every group of 10 people.
Then, both hands inner forearm uniformly and in laboratory test personnel is cleaned to subject, is sat quietly in laboratory, during which
Not tender practical joke is drunk water and beverage, and forearm exposure keeps loosening, after spontaneously drying 0.5 hour, choose respectively in both hands inner forearm
3cm2Region as tested area, its corresponding test sample is smeared in inside respectively before the both hands arm of control group and experimental group 1-5 group
0.2mL, the 0.5th after smearing respectively, 1,2,4,6h each time point surveys empire with skin epidermis water content tester and records each
The moisture content in the tested area in inside before subject's both hands arm.
Take the moisture of skin of the average value of the moisture content in the tested area in inside before subject's both hands arm as the subject
Content measuring as a result, take skin of the average value of the moisture content test result of the skin of each group subject as this group of subject again
The moisture content test result of skin.
The difference of the moisture content of skin before and after test sample, and the skin with blank control group are smeared by comparison each group respectively
The difference of water content judges long-term moisture-keeping efficacy of the invention.
3) experimental result
The moisture content test result of each volunteer's skin is as shown in table 2
The specific experiment result of 2 each group experimental group of table and control group
| Group | 0.5h | 1h | 2h | 4h | 6h |
| Blank control | 27.9 | 27.5 | 27.4 | 27.3 | 27.2 |
| Control group | 40.5 | 30.9 | 29.1 | 28.5 | 27.5 |
| 1 group of experimental group | 56.3 | 49.1 | 45.3 | 43.2 | 39.9 |
| 2 groups of experimental group | 56.8 | 49.5 | 46.8 | 43.5 | 40.1 |
| 3 groups of experimental group | 56.9 | 49.9 | 47.1 | 43.9 | 40.5 |
| 4 groups of experimental group | 57.1 | 50.2 | 48.1 | 44.1 | 41.9 |
| 5 groups of experimental group | 56.7 | 49.1 | 46.9 | 43.5 | 39.5 |
By table 2 and Fig. 2 using the experimental result of cuticula change of moisture content figure after the present composition it is found that blank control
Water content in group in volunteer's skin has almost no change, experimental group compared with the control group, after test sample 6h, experimental group
The water content of middle volunteer's skin times is so very high, this illustrates that probiotic composition of the invention has apparent long-term benefit to skin
Water moisture-keeping functions.
The above described is only a preferred embodiment of the present invention, be not intended to limit the present invention in any form, therefore
Without departing from the technical solutions of the present invention, to the above embodiments according to the technical essence of the invention any simply to repair
Change, equivalent variations and modification, all of which are still within the scope of the technical scheme of the invention.
Claims (9)
1. a kind of for skin moisture-keeping, the probiotic composition of barrier protection, it is characterised in that: it is based on the total weight of the composition,
The probiotic composition includes following components:
Saccharomycete/1-40 parts of rice fermentation product；1-30 parts of lactic acid bacteria lysate, two split saccharomycetes to make fermentation product lysis object 1-
30 parts；1-30 parts of thermus thermophilus tunning.
2. probiotic composition as described in claim 1, it is characterised in that: be based on the total weight of the composition, the probiotics
Composition includes following components:
Saccharomycete/15-40 parts of rice fermentation product；15-30 parts of lactic acid bacteria lysate, two split saccharomycetes to make fermentation product lysis object
15-30 parts；15-30 parts of thermus thermophilus tunning.
3. probiotic composition as claimed in claim 2, it is characterised in that: the saccharomycete/rice fermentation product is rice
Rice fermentation Product filtrate after saccharomycetes to make fermentation.
4. as claimed in claim 2 for skin moisture-keeping, the probiotic composition of barrier protection, it is characterised in that: the ferment
Female bacterium is that brewer's yeast, saccharomyces uvarum, Hansenula yeast, torulopsis, Candida, pichia, rhodotorula are therein
One or more of compositions；Its volume ratio is 1:1-3:1-4:1-5, concentration 105-108CFU/ml。
5. as claimed in claim 2 for skin moisture-keeping, the probiotic composition of barrier protection, it is characterised in that: the cream
Sour bacterium is lactobacillus bulgaricus, cheese lactic acid bacteria, lactobacillus acidophilus, streptococcus thermophilus, lactobacillus plantarum, Lactobacillus rhamnosus
One such or several composition.
6. as described in claim 1 for skin moisture-keeping, the probiotic composition of barrier protection, it is characterised in that: the ferment
Female bacterium/rice fermentation product bacterium colony concentration is 106-108CFU/g；The bacterium colony concentration of the lactic acid bacteria lysate is 106-
108CFU/g；The described two bacterium colony concentration for splitting saccharomycetes to make fermentation product lysis object are 106-108CFU/g；The thermus thermophilus hair
The bacterium colony concentration of ferment product is 106-108CFU/g；Weight ratio between four is 1:1-5:1-5:1-5.
7. of any of claims 1-6 for skin moisture-keeping, the probiotic composition of barrier protection, feature exists
In:
Respectively by saccharomycete/1-40 parts of rice fermentation product；1-30 parts of lactic acid bacteria lysate, two to split saccharomycetes to make fermentation product molten
1-30 parts of born of the same parents' object；1-30 parts of thermus thermophilus tunning are mixed, and are added to any required skin moisture-keeping, barrier
In the cosmetics of protection.
8. application of the probiotic composition of any of claims 1-6 in cosmetics, it is characterised in that: describedization
Cosmetic contains the probiotic composition of 5~10wt%；And the customary adjuvant of 90~99wt%.
9. application of the probiotic composition as claimed in claim 8 in cosmetics, it is characterised in that: the customary adjuvant packet
Containing surfactant, thickener, conditioner, moisturizer, preservative, chelating agent, essence, one of deionized water or a variety of；
The cosmetics are face cream, facial mask, Essence, toner, lotion or facial cleanser.
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| CN114652670A (en) * | 2022-04-25 | 2022-06-24 | 广州诺胜化妆品有限公司 | Composition for promoting skin microecological balance |
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| CN111728935A (en) * | 2020-07-08 | 2020-10-02 | 广州澳希亚实业有限公司 | Probiotic-containing micro-ecological particle and preparation method and application thereof |
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| CN113018246A (en) * | 2021-03-16 | 2021-06-25 | 广东格物生物科技有限公司 | Probiotic shampoo capable of relieving scalp inflammation and preparation method thereof |
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| CN113208999A (en) * | 2021-05-21 | 2021-08-06 | 广州市万千粉丝化妆品有限公司 | Probiotic composition for repairing skin and application of probiotic composition in cosmetics |
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