CN108096081A - The composition of one primary yeast extractive from fermentative and its application in cosmetics - Google Patents

The composition of one primary yeast extractive from fermentative and its application in cosmetics Download PDF

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Publication number
CN108096081A
CN108096081A CN201711447203.5A CN201711447203A CN108096081A CN 108096081 A CN108096081 A CN 108096081A CN 201711447203 A CN201711447203 A CN 201711447203A CN 108096081 A CN108096081 A CN 108096081A
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yeast
composition
fermentative
skin
extractive
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陈瑛
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Shanghai Lalisi Trading Co Ltd
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Shanghai Lalisi Trading Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/004Aftersun preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/10General cosmetic use
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/85Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
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  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses the composition of a primary yeast extractive from fermentative, including:Two split yeast tunning lysis object 75~95% and surplus for polynary ferment compound.Wherein, polynary ferment compound includes lactobacillus-fermented product and saccharomycetes to make fermentation Product filtrate.The invention also discloses application of the composition in cosmetics of this primary yeast extractive from fermentative.The present invention is damaged by splitting the uvioresistant of yeast tunning lysis object and polynary ferment compound with reference to two and purification maintenance, it is anti-oxidant, crease-resistant the effect of, the synergistic effect of skin care is played with polynary yeast simultaneously, is realized for the multiple nursing effect of skin and safety, permanent effective nursing.

Description

The composition of one primary yeast extractive from fermentative and its application in cosmetics
Technical field
The present invention relates to cosmetics preparation field, more particularly to the composition of a primary yeast extractive from fermentative and its making up Application in product.
Background technology
The development of modern cosmetics industry, market to the whitening of cosmetics, moisturizing, hide the multi-functional demand such as the flaw increasingly Urgently.Make a general survey of whitening product on sale in the market, most whitening mechanism are both for causing cutaneous pigmentation and obscure black Pigment, the generation for reducing melanin by inhibiting the activity of tyrosinase or by by the melanin generated carry out Catabolism, reduction and block its to skin surface migrate, so as to achieve the effect that whitening skin lightening.Currently used whitening is lived Property ingredient mainly has the chemical synthesis preparations such as licoflavone, ursin, vitamin C and its derivative, tartaric acid.But these whitenings The action pathway of agent is single, and the colour of skin of skin suffers from the double influence of inherent oneself factor and external environment factor, together Shi Xiaoguo is and not fully up to expectations there are individual difference, and there is also risks for security.
In recent years, biochemical products, as yeast and its metabolin substitute chemical synthesis preparation as cosmetics main component into For upsurge.In fact before 8000, medieval people are known that be made wine using the active material of saccharomycete, Cuba's ratio Human relations people helps wound healing using beer and yeast, Greece women also commonly use the foam of brewing fermentation generation clean face and Body keeps the healthy and beautiful of skin with this.
Mechanism with yeast skin care is mainly that yeast is a kind of fungal cell in itself, and except amino acid, nucleotide, it is also There are monose, disaccharides and a lot of beneficiating ingredients of minerals, vitamin etc.;And yeast extract is carried from unartificial yeast A kind of active matter taken, itself has use value, while can also be used as the material of skin care.At present, if people imagine energy It is enough yeast cells is utilized with control, it is made to generate different metabolins under different life conditions, these metabolins Then it is likely to become the core material of skin anti-aging, whitening etc..
During realizing that yeast metabolism object is converted into skin care item, inventor has found that the prior art is at least asked there are following Topic:1st, yeast is one kind of fungi, and being added directly into skin-protection product can cause the flora on skin exceeded, to skin or even people Body is done harm rather than good;2nd, existing yeast metabolism object skin care item effect is single, is difficult to meet the multi-efficiencies such as whitening, moisturizing, anti-aging.
The content of the invention
In order to solve the problems, such as that yeast metabolism object skin care item effect is single, skin care comprehensive performance is insufficient in the prior art, this The composition and its application in cosmetics that inventive embodiments provide a primary yeast extractive from fermentative.The technical solution is such as Under:
On the one hand, an embodiment of the present invention provides the composition of a primary yeast extractive from fermentative, including following components:
Two split yeast tunning lysis object:75~95%,
Polynary ferment compound:Surplus;
The polynary ferment compound includes lactobacillus-fermented product and saccharomycetes to make fermentation Product filtrate.
Preferably, the composition of a primary yeast extractive from fermentative, including following components:
Two split yeast tunning lysis object:95%,
Polynary ferment compound:4.5%, specifically include lactobacillus-fermented product:2.0% and saccharomycetes to make fermentation product filter Liquid:2.5%.
Optionally, the composition of a primary yeast extractive from fermentative, including following components:
Two split yeast tunning lysis object:75%,
Polynary ferment compound:25.0%, specifically include lactobacillus-fermented product:20.0% and saccharomycetes to make fermentation product filter Liquid:25.0%.
Further, the polynary ferment compound further includes acidophil/grape fermentation product and bright string coccus/radish root Tunning filtrate.
On the other hand, the embodiment of the invention also discloses composition the answering in cosmetics of above-mentioned yeast extractive from fermentative With.
Specifically, application of the composition of above-mentioned yeast extractive from fermentative in Essence is prepared.
Application of the composition of above-mentioned yeast extractive from fermentative in lotion is prepared.
Application of the composition of above-mentioned yeast extractive from fermentative in face cream is prepared.
The advantageous effect that technical solution provided in an embodiment of the present invention is brought is:
1st, the embodiment of the present invention is combined by splitting yeast tunning lysis object by two with polynary ferment compound, comprehensive The synergistic effect that make use of more yeast metabolism object skin cares is closed, softening aging cutin is realized, promotes skin vigor and elasticity, and have The effect of having bright color, making skin profit white fine and smooth;
2nd, the embodiment of the present invention splits yeast tunning lysis object using two has the n DNA after promoting ultraviolet light irradiation Repair mechanism, the UV-induced smooth aging of confrontation prevent ultraviolet light from triggering immunosupress, the work(for preventing double-strand break Effect can protect skin to resist ultraviolet injury, human body is made to maintain vigour;
3rd, the embodiment of the present invention prepares active ingredient using biofermentation and broken wall purification technique, and skin-friendly is good, oozes It is thoroughly fast, make skin-whitening safer, effective, lasting.
Specific embodiment
It to make the object, technical solutions and advantages of the present invention clearer, below will be to the technology in the embodiment of the present invention Scheme is clearly and completely described, it is clear that described embodiment be only part of the embodiment of the present invention rather than entirely The embodiment in portion.Based on the embodiments of the present invention, those of ordinary skill in the art are without making creative work All other embodiments obtained belong to the scope of protection of the invention.
Embodiment 1
An embodiment of the present invention provides the composition of a primary yeast extractive from fermentative, including following components:
Two split yeast tunning lysis object:95%,
Polynary ferment compound:4.5%, specifically include lactobacillus-fermented product:2.0% and saccharomycetes to make fermentation product filter Liquid:2.5%.
Two split yeast tunning lysis object, include the filtrate of metabolite after fermentation, have after promoting ultraviolet light irradiation N DNA repair mechanism, the UV-induced smooth aging of confrontation, prevent ultraviolet light from triggering immunosupress, preventing double-strand The effect of fracture, can protect skin to resist ultraviolet injury, human body is made to maintain vigour.
The present invention additionally uses the compound of polynary yeast, and the extracting solution of a variety of yeast metabolism objects is made full use of to play skin care Synergistic effect, while realizes more effect skin cares, can be effectively improved the tanning severely, dry of skin appearance, pore is coarse, sensitivity is general The problems such as red, the dry line of microgroove, acne print deposition, make flesh bottom healthier.
Yeast has been obtained for being widely applied on skin care item simultaneously, but it is not yeast to be used in skin care item Itself, but the extract of yeast or metabolism filtrate.As a kind of efficient active matter of safe nutrition, yeast in skin care item into It must pass through stringent extraction, test and assessment to divide.The embodiment of the present invention passes through biofermentation and broken wall purification technique system Standby active ingredient.
The biofermentation purifying technique that the embodiment of the present invention uses, using the specific trait and function of yeast, passes through the modern times Chemical industry journey technology and equipment come produce utility or by yeast be directly used in industrialized production obtain purpose product technology body System.Including fermenting and purifying two processes.By required two split yeast and lactic acid bacteria, saccharomycete metabolite from zymotic fluid In the process separated.Specific purifying technique includes clasmatosis, separation, mash conveying, filtering and impurity removing, ion exchange electric osmose Analysis, reverse osmosis, ultrafiltration, gel filtration, precipitation separation and subsequent solvent extraction, evaporate, crystallize, distillation, dry packing etc. Process and unit operation.Compared with common separating-purifying step, the phytomicroorganism elite recovery rate of biofermentation purification is high Up to more than 95%.
The advantageous effect that technical solution provided in an embodiment of the present invention is brought is:
1st, the embodiment of the present invention is combined by splitting yeast tunning lysis object by two with polynary ferment compound, comprehensive The synergistic effect that make use of more yeast metabolism object skin cares is closed, softening aging cutin is realized, promotes skin vigor and elasticity, and have The effect of having bright color, making skin profit white fine and smooth;
2nd, the embodiment of the present invention splits yeast tunning lysis object using two has the n DNA after promoting ultraviolet light irradiation Repair mechanism, the UV-induced smooth aging of confrontation prevent ultraviolet light from triggering immunosupress, the work(for preventing double-strand break Effect can protect skin to resist ultraviolet injury, human body is made to maintain vigour;
3rd, the embodiment of the present invention can prepare the activity of yeast compositions kind by biofermentation and broken wall purification technique Ingredient, has that skin-friendly is good, quick permeation, the advantages of making skin-whitening safer, effective, lasting.
Embodiment 2
Further, the composition the embodiment of the invention also discloses above-mentioned yeast extractive from fermentative is in Essence is prepared Application.
Amino acid, protein, minerals and carbohydrate there are many containing in yeast extract.Therefore with a variety of skin cares Function, yeast have been obtained for being widely applied on skin care item, but be used in skin care item not be yeast in itself, and It is the extract of yeast or metabolism filtrate.As a kind of efficient active matter of safe nutrition, the zymasis in skin care item is certain It is to pass through stringent extraction, test and assessment.
Specifically, the embodiment of the invention discloses composition the answering in Essence is prepared of above-mentioned yeast extractive from fermentative With.
The composition of Essence includes the composition of aqua, emulsion and above-mentioned yeast extractive from fermentative, and specific ratio is as follows:
1st, the aqua of dissolving active component is prepared
The component of the aqua is:
The preparation method of aqua is:
S1, Sodium Hyaluronate is added in deionized water, stirring and dissolving;
S2, remaining component, stirring and dissolving are added in;
S3, pH value is adjusted to 5.5~7.0, that is, aqua is made.
2nd, the emulsion in Essence is prepared
The component of the emulsion is:
The preparation method of emulsion is:
(1) above-mentioned all components are uniformly mixed, are heated to 80 DEG C, stir to dissolve, obtain mixed solution;
(2) acrylic acid (ester) class/C10-30 alkylol acrylamide acid esters cross-linked polymer is added in deionized water, stirring and dissolving Afterwards, mixed solution made from addition (1), is heated to 80 DEG C, stirs to dissolve;
(3) glycerite is added in, stirs emulsifying;
(4) stirring is cooled to 45 DEG C, adjust pH value between 5.5~6.5 to get to emulsion.
3rd, the composition of yeast extractive from fermentative is prepared
The biofermentation purifying technique that the embodiment of the present invention uses, using the specific trait and function of yeast, passes through the modern times Chemical industry journey technology and equipment come produce utility or by yeast be directly used in industrialized production obtain purpose product technology body System.Including fermenting and purifying two processes.The metabolite for required two being split yeast and other yeast divides from zymotic fluid Separate out the process come.Specific purifying technique include clasmatosis, separation, mash conveying, filtering and impurity removing, ion exchange electrodialysis, Reverse osmosis, ultrafiltration, gel filtration, precipitation separation and subsequent solvent extraction, evaporate, crystallize, distillation, dry packing waited Journey and unit operation.Compared with common separating-purifying step, the phytomicroorganism elite recovery rate of biofermentation purification is up to More than 95%.
The yeast extract composition obtained by above-mentioned biofermentation purifying technique is included into following component and ratio:
Two split yeast tunning lysis object:95.0%
Polynary ferment compound:5.0%
Wherein, the polynary ferment compound include lactobacillus fermentation lysate, acidophil/grape fermentation product, Bright string coccus/radish root tunning filtrate, saccharomycetes to make fermentation Product filtrate, proportion is respectively 2.0%, 1.0%, 1.0%th, 1.0%;
Above-mentioned each component is mixed to form the yeast extract composition in corresponding ratio.
4th, the Essence containing yeast metabolism compositions is prepared
The above-mentioned yeast extract group obtained after emulsion and biofermentation purification is added in the aqua being prepared 8 parts of object is closed, that is, the Essence is prepared.
The advantageous effect that technical solution provided in an embodiment of the present invention is brought is:
1st, the embodiment of the present invention is protected by splitting the multicomponent of yeast tunning lysis object and polynary ferment compound by two The synergistic effect of skin realizes softening aging cutin, promotes skin vigor and elasticity, and with bright color, makes skin profit white The effect of fine and smooth;
2nd, the embodiment of the present invention splits yeast tunning lysis object using two has the n DNA after promoting ultraviolet light irradiation Repair mechanism, the UV-induced smooth aging of confrontation prevent ultraviolet light from triggering immunosupress, preventing double-strand break (micronucleus) The effect of, skin can be protected to resist ultraviolet injury, human body is made to maintain vigour;
3rd, the embodiment of the present invention prepares active ingredient using biofermentation and broken wall purification technique, and skin-friendly is good, oozes It is thoroughly fast, make skin-whitening safer, effective, lasting.
Embodiment 3
Further, the composition the embodiment of the invention also discloses above-mentioned yeast extractive from fermentative is in lotion is prepared Using.
Amino acid, protein, minerals and carbohydrate there are many containing in yeast extract.Therefore with a variety of skin cares Function, yeast have been obtained for being widely applied on skin care item, but be used in skin care item not be yeast in itself, and It is the extract of yeast or metabolism filtrate.As a kind of efficient active matter of safe nutrition, the zymasis in skin care item is certain It is to pass through stringent extraction, test and assessment.
Adding the beauty functions of the yeast extract in skin care item includes:(1) cytoactive is increased;(2) cell is increased Repair ability and defense function;(3) oxidation resistance;(4) whitening capability.
Specifically, application of the composition of above-mentioned yeast extractive from fermentative in lotion is prepared.
1st, lotion is prepared
The component of the lotion is:
First phase:
Second phase:
Third phase:
The preparation method of lotion is:
(1) the first phase all components are uniformly mixed, are heated to 80 DEG C, stir to dissolve, obtain the first phase solution;
(2) acrylic acid (ester) class in the second phase/C10-30 alkylol acrylamide acid esters cross-linked polymer is added in into deionized water In, after stirring and dissolving, the phase other raw materials are added in, 80 DEG C is heated to, stirs to dissolve, obtain the second phase solution;
(3) (1) is added to (2) preparation-obtained solution to mix, stirs emulsifying;
(4) stirring is cooled to 45 DEG C, adds in the aminomethyl propanol of third phase, after stirring and dissolving, adds in the phase remaining component, Stirring is cooled to 30~35 DEG C;
(5) pH value is adjusted between 5.5~6.5, that is, lotion is prepared.
2nd, the composition of yeast extractive from fermentative is prepared
The biofermentation purifying technique that the embodiment of the present invention uses, using the specific trait and function of yeast, passes through the modern times Chemical industry journey technology and equipment come produce utility or by yeast be directly used in industrialized production obtain purpose product technology body System.Including fermenting and purifying two processes.The metabolite for required two being split yeast and other yeast divides from zymotic fluid Separate out the process come.Specific purifying technique include clasmatosis, separation, mash conveying, filtering and impurity removing, ion exchange electrodialysis, Reverse osmosis, ultrafiltration, gel filtration, precipitation separation and subsequent solvent extraction, evaporate, crystallize, distillation, dry packing waited Journey and unit operation.Compared with common separating-purifying step, the phytomicroorganism elite recovery rate of biofermentation purification is up to More than 95%.
The yeast extract composition obtained by above-mentioned biofermentation purifying technique is included into following component and ratio:
Two split yeast tunning lysis object:75.0%,
Polynary ferment compound:25.0%.
Wherein, the polynary ferment compound include lactobacillus fermentation lysate, acidophil/grape fermentation product, Bright string coccus/radish root tunning filtrate, saccharomycetes to make fermentation Product filtrate, proportion is respectively 11.0%, 11.0%, 1.0%th, 2.0%;
Above-mentioned each component is mixed to form the yeast extract composition in corresponding ratio.
3rd, the lotion containing yeast metabolism compositions is prepared
The above-mentioned yeast extract group obtained after emulsion and biofermentation purification is added in the aqua being prepared 12 parts of object is closed, that is, the lotion is prepared.
The advantageous effect that technical solution provided in an embodiment of the present invention is brought is:
1st, the embodiment of the present invention is combined by splitting yeast tunning lysis object by two with polynary ferment compound, comprehensive The synergistic effect that make use of more yeast metabolism object skin cares is closed, softening aging cutin is realized, promotes skin vigor and elasticity, and have The effect of having bright color, making skin profit white fine and smooth;
2nd, the embodiment of the present invention splits yeast tunning lysis object using two has the n DNA after promoting ultraviolet light irradiation Repair mechanism, the UV-induced smooth aging of confrontation prevent ultraviolet light from triggering immunosupress, the work(for preventing double-strand break Effect can protect skin to resist ultraviolet injury, human body is made to maintain vigour;
3rd, the embodiment of the present invention can prepare the activity of yeast compositions kind by biofermentation and broken wall purification technique Ingredient, has that skin-friendly is good, quick permeation, the advantages of making skin-whitening safer, effective, lasting.
Embodiment 4
Further, the composition the embodiment of the invention also discloses above-mentioned yeast extractive from fermentative is in face cream is prepared Using.
Amino acid, protein, minerals and carbohydrate there are many containing in yeast extract.Therefore with a variety of skin cares Function, yeast have been obtained for being widely applied on skin care item, but be used in skin care item not be yeast in itself, and It is the extract of yeast or metabolism filtrate.As a kind of efficient active matter of safe nutrition, the zymasis in skin care item is certain It is to pass through stringent extraction, test and assessment.
Adding the beauty functions of the yeast extract in skin care item includes:(1) cytoactive is increased;(2) cell is increased Repair ability and defense function;(3) oxidation resistance;(4) whitening capability.
Specifically, application of the composition of above-mentioned yeast extractive from fermentative in face cream is prepared.
A kind of face cream for including foregoing yeast extractive from fermentative, each raw material weight percentage composition are as follows:
Component A:Lecithin, 2 parts, 1.5 parts of Sucrose Polystearic Acid Esters, 4.5 parts of Parleam, docosyl alcohol polyethers -251 Part, 3 parts of C15-19 alkane, 1.5 parts of ring five dimethyl silicone polymer, 2 parts of dimethyl silicone polymer, 2 parts of avocado oil, tocopherol second 0.3 part of acid esters;
B component:0.1 part of ethylenediamine tetra-acetic acid, 4 parts of glycerine, 4 parts of butanediol, 0.5 part of carbomer;Sodium ascorbate 0.5 Part;Deionized water, surplus;
Component C:0.5 part of triethanolamine;
D components:2 parts of yeast extract composition;
Component E:0.1 part of collargol.
Wherein, the ferment compound in D components is deionized water, two split yeast lysis object and the group of other yeast extracts Object, Phenoxyethanol are closed, deionized water, urea, trehalose, inositol, taurine, glycine betaine, Phenoxyethanol are mixed with Yeast extract composition, additive amount are 2.5% (mass ratio) of total amount.
Wherein, the step of composition for preparing yeast extractive from fermentative, includes:
The biofermentation purifying technique that the embodiment of the present invention uses, using the specific trait and function of yeast, passes through the modern times Chemical industry journey technology and equipment come produce utility or by yeast be directly used in industrialized production obtain purpose product technology body System.Including fermenting and purifying two processes.The metabolite for required two being split yeast and other yeast divides from zymotic fluid Separate out the process come.Specific purifying technique include clasmatosis, separation, mash conveying, filtering and impurity removing, ion exchange electrodialysis, Reverse osmosis, ultrafiltration, gel filtration, precipitation separation and subsequent solvent extraction, evaporate, crystallize, distillation, dry packing waited Journey and unit operation.Compared with common separating-purifying step, the phytomicroorganism elite recovery rate of biofermentation purification is up to More than 95%.
The yeast extract composition obtained by above-mentioned biofermentation purifying technique is included into following component and ratio:
Two split yeast tunning lysis object:75.0%,
Polynary ferment compound:25.0%.
Wherein, the polynary ferment compound includes lactobacillus-fermented lysate, acidophil/grape fermentation product, bright Go here and there coccus/radish root tunning filtrate, saccharomycetes to make fermentation Product filtrate, proportion is respectively 11.0%, 10.0%, 1.0%th, 3.0%;
Above-mentioned each component is mixed to form the yeast extract composition in corresponding ratio..
The preparation method of face cream comprises the following steps:
(1) each ingredient mixing of component A is heated to 75 DEG C;
(2) mixing of B component raw material is heated to 80 DEG C;
(3) when temperature reaches, B component is added in component A uniformly mixed homogeneous and obtains mixed phase;
(4) after mixed phase being cooled to 40 DEG C, C groups, D groups and E groups is added in, stirs evenly, discharges after cooling, that is, be made and contain There is the face cream of yeast metabolism compositions.
The advantageous effect that technical solution provided in an embodiment of the present invention is brought is:
1st, the embodiment of the present invention is combined by splitting yeast tunning lysis object by two with polynary ferment compound, comprehensive The synergistic effect that make use of more yeast metabolism object skin cares is closed, softening aging cutin is realized, promotes skin vigor and elasticity, and have The effect of having bright color, making skin profit white fine and smooth;
2nd, the embodiment of the present invention splits yeast tunning lysis object using two has the n DNA after promoting ultraviolet light irradiation Repair mechanism, the UV-induced smooth aging of confrontation prevent ultraviolet light from triggering immunosupress, the work(for preventing double-strand break Effect can protect skin to resist ultraviolet injury, human body is made to maintain vigour;
3rd, the embodiment of the present invention can prepare the activity of yeast compositions kind by biofermentation and broken wall purification technique Ingredient, has that skin-friendly is good, quick permeation, the advantages of making skin-whitening safer, effective, lasting.
In order to further verify the effect of application of the yeast metabolism compositions in cosmetics possesses, embodiment 2 is made Essence, face cream carries out corresponding human experimentation made from lotion made from embodiment 3 and embodiment 4.Specific experiment mistake Journey and result are as follows:
1st, sample
Essence made from embodiment 2, lotion made from embodiment 3 and face cream made from embodiment 4;
Commercially available cleawhite over-night essences, lotion and face cream (main component:Radix Glycyrrhizae, butter fruit, pearl powder etc.).
2nd, experimental method
Voluntary 120 people of trier (60 people of male, 60 people of women, age 18-25 Sui) is chosen, face has pigementation, skin The problems such as skin is dark yellow, dry, no cosmetic allergic contact dermatitis history.
Volunteer is divided into 6 groups, every group of 20 people, male to female ratio is fifty-fifty.
First group, try out 2 product of embodiment;Second group, try out commercially available cleawhite over-night essences;
3rd group, try out 3 product of embodiment;4th group, try out commercially available whitening emulsion;
5th group, 4 product of embodiment is tried out, the 6th group, tries out commercially available whitening cream.
Application method:Sooner or later after cleaning face, appropriate Evaluation product is taken uniformly to be applied to face, gently pats and absorb, and It gently massages 3-5 minutes, skin is allowed to fully absorb, it is continuous 8 weeks on probation.By questionnaire form, investigation trier is to using production The subjective assessment of product, including freckle effect, the indexs such as whitening effect and the dry and astringent, excitement of product.It the results are shown in Table 1.
3rd, experimental result
1 trier of table is to product evaluation application form
Table 1 is trier to the evaluation table of Evaluation product, in table the results show that in addition yeast metabolism compositions Afterwards, the embodiment of the present invention 2, embodiment 3 and 4 whitening product of embodiment have preferable whitening function, whitening, the work of moist skin With being substantially better than commercial like product;Three kinds of embodiment products are without allergy and excitement, Product Safety height.
The foregoing is merely presently preferred embodiments of the present invention, is not intended to limit the invention, it is all the present invention spirit and Within principle, any modifications, equivalent replacements and improvements are made should all be included in the protection scope of the present invention.

Claims (7)

1. the composition of a primary yeast extractive from fermentative, which is characterized in that including following components:
Two split yeast tunning lysis object:75~95%,
Polynary ferment compound:Surplus;
The polynary ferment compound includes lactobacillus-fermented product and saccharomycetes to make fermentation Product filtrate.
2. the composition of yeast extractive from fermentative according to claim 1, which is characterized in that
Two split yeast tunning lysis object:95%,
Polynary ferment compound:4.5%, specifically include lactobacillus-fermented product:2.0% and saccharomycetes to make fermentation Product filtrate: 2.5%.
3. the composition of yeast extractive from fermentative according to claim 1, which is characterized in that
Two split yeast tunning lysis object:75%,
Polynary ferment compound:25.0%, specifically include lactobacillus-fermented product:20.0% and saccharomycetes to make fermentation Product filtrate: 25.0%.
4. the composition of yeast extractive from fermentative according to claim 1, which is characterized in that the polynary ferment compound Further include acidophil/grape fermentation product and bright string coccus/radish root tunning filtrate.
5. application of the composition of yeast extractive from fermentative as described in claim 1 in Essence is prepared.
6. application of the composition of yeast extractive from fermentative as described in claim 1 in lotion is prepared.
7. application of the composition of yeast extractive from fermentative as described in claim 1 in face cream is prepared.
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