CN108125810B - Composite moisturizing and repairing composition and preparation method and application thereof - Google Patents
Composite moisturizing and repairing composition and preparation method and application thereof Download PDFInfo
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Abstract
The invention discloses a composite moisturizing and repairing composition which is prepared from the following components: sodium hyaluronate, dendrobe polysaccharide, tremella heteropolysaccharide, polyglutamic acid, -polylysine, betaine, trehalose, erythritol, glucan, peptide bimolecular lipophilic and hydrophilic surfactant, glycerol, 1,3 propylene glycol, 1,3 butylene glycol and water. The invention also provides a preparation method and application of the composite moisturizing and repairing composition. The composite moisturizing and repairing composition overcomes the defects of a single moisturizing raw material and a single repairing raw material, and achieves the moisturizing and repairing effects which cannot be achieved by the single raw material.
Description
Technical Field
The invention relates to the field of cosmetics, in particular to a composite moisturizing and repairing composition and a preparation method and application thereof.
Background
The skin care product is a product which is necessary for women and even a part of men every day at present, and comprises a facial mask, lotion, moisturizing repair essence milk, moisturizing repair essence cream and the like, wherein the facial mask is the most important and aims to make up the cleaning work of makeup removal and face washing which is still insufficient, and other maintenance functions such as moisturizing, whitening, anti-aging, grease balancing and the like are realized by matching with other essence components on the basis; the toning lotion is a transparent liquid cosmetic, is applied to the surface of skin and is used for cleaning the skin and keeping the skin healthy; the moisturizing repair essence is suitable for various skins, is an extreme product in skin care products, has delicate components, strong efficacy and obvious effect, and has the functions of preventing aging, resisting wrinkles, moisturizing, whitening, removing spots and the like; the moisturizing repair essence emulsion is emulsion-shaped, is slightly thicker than the essence, and has moderate water and oil proportion; essence cream, cream-like, essence cream is equivalent to essence + cream.
At present, with the continuous innovation of modern people along with science, the requirements of the beauty and hairdressing industry on product raw materials are developed from single raw materials to diversification, and in the skin care product, the raw materials of the products on the market are different, and the raw materials are too single, so that the skin care product is more and more not suitable for the requirements of the existing raw materials.
Disclosure of Invention
In order to overcome the defects of the prior art, the invention aims to provide the composite moisturizing and repairing composition, which overcomes the defects of a single moisturizing raw material and a single repairing raw material and has the moisturizing and repairing effects which cannot be achieved by the single raw material.
The invention also aims to provide a preparation method of the composite moisturizing and repairing composition, which has simple steps and simple and convenient operation and is suitable for large-scale industrial production.
The composite moisturizing repair composition can be simultaneously applied to the mask, the lotion, the moisturizing repair essence emulsion or the moisturizing repair essence cream, so that the raw materials are diversified and developed, and a better moisturizing repair effect is shown.
One of the purposes of the invention is realized by adopting the following technical scheme:
the composite moisturizing and repairing composition is prepared from the following components in percentage by mass:
the sum of the mass percentages of the components is 100 percent.
Further, the sodium hyaluronate is one or more than two of sodium hyaluronate A, sodium hyaluronate B, sodium hyaluronate C, sodium hyaluronate D, sodium hyaluronate E, sodium hyaluronate F and sodium hyaluronate G; wherein the molecular weight of the sodium hyaluronate A is more than 200 ten thousand, the molecular weight of the sodium hyaluronate B is 150-190 ten thousand, the molecular weight of the sodium hyaluronate C is 150-150 ten thousand, the molecular weight of the sodium hyaluronate D is 50-100 ten thousand, the molecular weight of the sodium hyaluronate E is 10-50 ten thousand, the molecular weight of the sodium hyaluronate F is 1-10 ten thousand, and the molecular weight of the sodium hyaluronate G is 1-1 ten thousand.
The second purpose of the invention is realized by adopting the following technical scheme:
a preparation method of a composite moisturizing and repairing composition comprises the steps of weighing sodium hyaluronate, dendrobe polysaccharide, polyglutamic acid, polylysine and glucan according to a ratio, dispersing glycerol, 1,3 propanediol and 1,3 butanediol, adding the dispersed glycerol, 1,3 propanediol and 1,3 butanediol into water to dissolve, adding betaine, trehalose, erythritol and peptide bimolecular lipophilic and hydrophilic surfactant while stirring, and uniformly dissolving to obtain the composite moisturizing and repairing composition.
Further, the stirring speed is 800-.
The third purpose of the invention is realized by adopting the following technical scheme:
application of a composite moisturizing and repairing composition in facial masks, astringent, moisturizing and repairing essence emulsion or moisturizing and repairing essence cream.
Further, the mask is prepared from a phase A and a phase B; wherein the phase A comprises 0.1 percent of carbomer 940, 0.2 percent of allantoin, 0.5 percent of nicotinamide and 80.65 percent of water in percentage by mass; the phase B comprises 10.0 percent of composite moisturizing and repairing composition, 0.1 percent of caprylyl hydroximic acid, 0.3 percent of p-hydroxyacetophenone, 0.05 percent of essence and 0.1 percent of triethanolamine in percentage by mass; the preparation method of the mask specifically comprises the following steps: mixing, stirring and heating the phase A raw materials to 80 ℃, preserving heat for 30 minutes, and homogenizing at low speed for 5 minutes; cooling to 45 deg.C, adding the B phase raw material, stirring and dissolving to obtain facial mask containing the compound moisturizing repair composition.
Further, the toning lotion is prepared from a phase C and a phase D; wherein the phase C comprises 0.2% of aloe extract, 0.2% of allantoin, 0.5% of nicotinamide and 93.65% of water by mass percentage; the phase D comprises 5.0 percent of composite moisturizing and repairing composition, 0.1 percent of caprylyl hydroximic acid, 0.3 percent of p-hydroxyacetophenone and 0.05 percent of essence in percentage by mass; the preparation method of the toning lotion comprises the following steps: mixing, stirring and heating the phase C raw materials to 80 ℃ according to the proportion, preserving heat for 30 minutes, and homogenizing for 5 minutes; cooling to 45 deg.C, adding the D phase raw material, stirring and dissolving to obtain cosmetic water containing the composite moisturizing and repairing composition.
Further, the moisturizing and repairing essence is prepared from an E phase and an F phase; wherein the phase E comprises 0.2 percent of carbomer 940, 0.2 percent of allantoin, 0.5 percent of nicotinamide and 48.45 percent of water in percentage by mass; the phase E comprises 50.0 percent of the compound moisturizing and repairing composition, 0.1 percent of caprylyl hydroximic acid, 0.3 percent of hydroxyacetophenone, 0.05 percent of essence and 0.2 percent of triethanolamine; the preparation method of the moisturizing and repairing essence comprises the following steps: mixing, stirring and heating the raw materials of the E phase to 80 ℃ according to the proportion, preserving heat for 30 minutes, and homogenizing at low speed for 5 minutes; cooling to 45 ℃, adding the F-phase raw material, stirring and dissolving to obtain the moisturizing repair essence containing the composite moisturizing repair composition.
Further, the moisturizing and repairing essence milk is prepared from a G phase, an H phase and an I phase; wherein the G phase comprises 0.2 percent of carbomer 941, 0.2 percent of allantoin, 0.2 percent of methylparaben and 76.15 percent of water in percentage by mass; the H phase comprises 1.5 percent of stearic acid, 1.5 percent of cetearyl alcohol, 3.0 percent of squalane, 1.5 percent of glyceryl stearate, 2.0 percent of polyoxyethylene sorbitan monostearate and 3.0 percent of caprylic/capric triglyceride in percentage by mass; the phase I comprises 10.0 percent of composite moisturizing and repairing composition, 0.5 percent of phenoxyethanol, 0.05 percent of essence and 0.2 percent of triethanolamine in percentage by mass; the preparation method of the moisturizing and repairing essence milk comprises the following steps: mixing the raw materials of the G phase and the B phase respectively according to the proportion, stirring and heating to 80 ℃, preserving heat for 20 minutes, adding the H phase into the A phase under stirring, and homogenizing for 5 minutes; cooling to 45 ℃, adding the phase I raw material, and stirring for 10 minutes to obtain the repair essence milk containing the composite moisturizing repair composition.
Further, the moisturizing and repairing essence cream is prepared from a J phase, a K phase and an L phase; wherein the J phase comprises 0.35% of carbomer 934, 0.2% of allantois, 0.2% of methylparaben and 75.85% of water in percentage by mass; the K phase comprises 1.5 percent of stearic acid, 1.5 percent of cetostearyl alcohol, 3.0 percent of squalane, 1.5 percent of glyceryl stearate, 2.0 percent of polyoxyethylene sorbitan monostearate and 3.0 percent of caprylic/capric triglyceride in percentage by mass; the L phase comprises 10.0 percent of composite moisturizing and repairing composition, 0.5 percent of phenoxyethanol, 0.05 percent of essence and 0.35 percent of triethanolamine in percentage by mass; the preparation method of the moisturizing and repairing essence cream comprises the following steps: mixing J-phase raw materials and K-phase raw materials according to a ratio, stirring and heating to 80 ℃, preserving heat for 20 minutes, adding the J-phase raw materials into the K-phase raw materials under stirring, and homogenizing for 5 minutes; and cooling to 45 ℃, adding the L-phase raw material, and stirring for 10 minutes to obtain the moisturizing repair essence cream containing the composite moisturizing repair composition.
Compared with the prior art, the invention has the beneficial effects that:
(1) the composite moisturizing and repairing composition overcomes the defects of a single moisturizing raw material and a repairing raw material, and has the moisturizing and repairing effects which cannot be achieved by the single raw material;
(2) the preparation method of the composite moisturizing and repairing composition is simple in steps, simple and convenient to operate and suitable for large-scale industrial production;
(3) the composite moisturizing repair composition disclosed by the invention is applied to the mask, the lotion, the moisturizing repair essence emulsion or the moisturizing repair essence cream, and can be simultaneously applied to the mask, the lotion, the moisturizing repair essence emulsion or the moisturizing repair essence cream, so that the raw materials are diversified and developed, and a better moisturizing repair effect is shown.
Drawings
FIG. 1 is a graph showing the change in the average content of stratum corneum after application of example 6 and comparative examples 1 to 4;
FIG. 2 is the TEWL of the skin after application of example 6 and comparative examples 1-4.
Detailed Description
The present invention will be further described with reference to the accompanying drawings and the detailed description, and it should be noted that any combination of the embodiments or technical features described below can be used to form a new embodiment without conflict.
The composite moisturizing and repairing composition is prepared from the following components in percentage by mass:
the sum of the mass percentages of the components is 100 percent.
In a further embodiment, the sodium hyaluronate is one or more of sodium hyaluronate A, sodium hyaluronate B, sodium hyaluronate C, sodium hyaluronate D, sodium hyaluronate E, sodium hyaluronate F and sodium hyaluronate G; wherein the molecular weight of the sodium hyaluronate A is more than 200 ten thousand, the molecular weight of the sodium hyaluronate B is 150-190 ten thousand, the molecular weight of the sodium hyaluronate C is 150-150 ten thousand, the molecular weight of the sodium hyaluronate D is 50-100 ten thousand, the molecular weight of the sodium hyaluronate E is 10-50 ten thousand, the molecular weight of the sodium hyaluronate F is 1-10 ten thousand, and the molecular weight of the sodium hyaluronate G is 1-1 ten thousand. In the composite moisturizing and repairing composition, a biological fermented ingredient sodium hyaluronate is adopted.
The preparation method of the composite moisturizing repair composition comprises the steps of weighing sodium hyaluronate, dendrobe polysaccharide, polyglutamic acid, polylysine and glucan according to the proportion, dispersing glycerol, 1, 3-propanediol and 1, 3-butanediol, adding the dispersed glycerol, 1, 3-propanediol and 1, 3-butanediol into water for dissolving, adding betaine, trehalose, erythritol and peptide bimolecular lipophilic and hydrophilic surfactant while stirring, and uniformly dissolving to obtain the composite moisturizing repair composition.
As a further embodiment, the stirring speed is 800-1000r/min, and the stirring time is 10-20 min.
The composite moisturizing and repairing composition is applied to a facial mask, a lotion, a moisturizing and repairing essence emulsion or a moisturizing and repairing essence cream.
As a further embodiment, the mask is prepared from phase a and phase B; wherein the phase A comprises 0.1 percent of carbomer 940, 0.2 percent of allantoin, 0.5 percent of nicotinamide and 80.65 percent of water in percentage by mass; the phase B comprises 10.0 percent of composite moisturizing and repairing composition, 0.1 percent of caprylyl hydroximic acid, 0.3 percent of p-hydroxyacetophenone, 0.05 percent of essence and 0.1 percent of triethanolamine in percentage by mass; the preparation method of the facial mask specifically comprises the following steps: mixing, stirring and heating the phase A raw materials to 80 ℃, preserving heat for 30 minutes, and homogenizing at low speed for 5 minutes; cooling to 45 deg.C, adding the B phase raw material, stirring and dissolving to obtain facial mask containing the compound moisturizing repair composition.
As a further embodiment, the lotion is prepared from phase C and phase D; wherein the phase C comprises 0.2% of aloe extract, 0.2% of allantoin, 0.5% of nicotinamide and 93.65% of water by mass percentage; the phase D comprises 5.0 percent of composite moisturizing and repairing composition, 0.1 percent of caprylyl hydroximic acid, 0.3 percent of p-hydroxyacetophenone and 0.05 percent of essence in percentage by mass; the preparation method of the toning lotion comprises the following steps: mixing, stirring and heating the phase C raw materials to 80 ℃ according to the proportion, preserving heat for 30 minutes, and homogenizing for 5 minutes; cooling to 45 deg.C, adding the D phase raw material, stirring and dissolving to obtain cosmetic water containing the composite moisturizing and repairing composition.
As a further embodiment, the moisturizing repair essence is prepared from phases E and F; wherein the phase E comprises 0.2 percent of carbomer 940, 0.2 percent of allantoin, 0.5 percent of nicotinamide and 48.45 percent of water in percentage by mass; the phase E comprises 50.0 percent of the compound moisturizing and repairing composition, 0.1 percent of caprylyl hydroximic acid, 0.3 percent of hydroxyacetophenone, 0.05 percent of essence and 0.2 percent of triethanolamine; the preparation method of the moisturizing and repairing essence comprises the following steps: mixing, stirring and heating the raw materials of the E phase to 80 ℃ according to the proportion, preserving heat for 30 minutes, and homogenizing at low speed for 5 minutes; cooling to 45 ℃, adding the F-phase raw material, stirring and dissolving to obtain the moisturizing repair essence containing the composite moisturizing repair composition.
As a further embodiment, the moisturizing and repairing essence milk is prepared from a G phase, a H phase and a I phase; wherein the G phase comprises 0.2 percent of carbomer 941, 0.2 percent of allantoin, 0.2 percent of methylparaben and 76.15 percent of water in percentage by mass; the H phase comprises 1.5 percent of stearic acid, 1.5 percent of cetearyl alcohol, 3.0 percent of squalane, 1.5 percent of glyceryl stearate, 2.0 percent of polyoxyethylene sorbitan monostearate and 3.0 percent of caprylic/capric triglyceride in percentage by mass; the phase I comprises 10.0 percent of composite moisturizing and repairing composition, 0.5 percent of phenoxyethanol, 0.05 percent of essence and 0.2 percent of triethanolamine in percentage by mass; the preparation method of the moisturizing and repairing essence milk comprises the following steps: mixing the raw materials of the G phase and the B phase respectively according to the proportion, stirring and heating to 80 ℃, preserving heat for 20 minutes, adding the H phase into the A phase under stirring, and homogenizing for 5 minutes; cooling to 45 ℃, adding the phase I raw material, and stirring for 10 minutes to obtain the repair essence milk containing the composite moisturizing repair composition.
As a further embodiment, the moisturizing and repairing essence cream is prepared from a J phase, a K phase and a L phase; wherein the J phase comprises 0.35% of carbomer 934, 0.2% of allantois, 0.2% of methylparaben and 75.85% of water in percentage by mass; the K phase comprises 1.5 percent of stearic acid, 1.5 percent of cetostearyl alcohol, 3.0 percent of squalane, 1.5 percent of glyceryl stearate, 2.0 percent of polyoxyethylene sorbitan monostearate and 3.0 percent of caprylic/capric triglyceride in percentage by mass; the L phase comprises 10.0 percent of composite moisturizing and repairing composition, 0.5 percent of phenoxyethanol, 0.05 percent of essence and 0.35 percent of triethanolamine in percentage by mass; the preparation method of the moisturizing and repairing essence cream comprises the following steps: mixing J-phase raw materials and K-phase raw materials according to a ratio, stirring and heating to 80 ℃, preserving heat for 20 minutes, adding the J-phase raw materials into the K-phase raw materials under stirring, and homogenizing for 5 minutes; and cooling to 45 ℃, adding the L-phase raw material, and stirring for 10 minutes to obtain the moisturizing repair essence cream containing the composite moisturizing repair composition.
In the composite moisturizing repair composition, natural plant extracts and moisturizing components from plant sources are adopted: dendrobe polysaccharide, tremella heteropolysaccharide, betaine, trehalose, erythritol, glycerol, 1, 3-propanediol and 1, 3-butanediol. The dendrobium polysaccharide manufacturer is Shanghai cangue leaf industry Co., Ltd, the tremella heteropolysaccharide manufacturer is Zhongshan spring tree investment Co., Ltd, the betaine manufacturer is Texas Onlida biotechnology Co., Ltd, the trehalose manufacturer is Japan forest original company, the erythritol manufacturer is Shandong ternary Biotechnology Co., Ltd, the glycerol manufacturer is Malaysia Spirostric, the 1, 3-propanediol manufacturer is American Dow company, and the 1, 3-butanediol manufacturer is American OXEA company.
The composite moisturizing and repairing composition adopts the dendrobe polysaccharide, the dendrobe polysaccharide is derived from dendrobe which is ranked first in the Chinese medicine 'Jiudaoxiancao', and through test comparison, the moisturizing effect of the dendrobe polysaccharide is not inferior to that of sodium hyaluronate.
The composite moisturizing and repairing composition provided by the invention adopts tremella heteropolysaccharide which is a tonic of medicine and food, and is also a natural component with excellent moisturizing effect, 1 g of tremella heteropolysaccharide can adsorb 500 g of water, and the moisturizing effect is not inferior to that of sodium hyaluronate.
The compound moisturizing and repairing composition adopts the trehalose which has a magical protection effect on organisms, and because the trehalose can form a unique protective film on the surface of cells under severe environmental conditions of high temperature, high cold, high osmotic pressure, drying and dehydration and the like, protein molecules are effectively protected from being inactivated without denaturation, so that the life process and biological characteristics of a living body are maintained. Many species that exhibit extraordinary stress tolerance to the harsh environment are directly related to the presence of large amounts of trehalose in their bodies. The unique functional characteristic enables the trehalose to be used as an excellent activity protective agent for protein drugs, enzymes, vaccines and other biological products, also be an important component of cosmetics for keeping cell activity and moisture, and further be used for preventing food deterioration, keeping fresh flavor of food and improving food quality.
The composite moisturizing and repairing composition provided by the invention adopts erythritol, and the erythritol not only has the effects of moisturizing and preventing rough skin, but also has cool skin feeling, and can reduce the sticky skin feeling of other moisturizing agents.
The composite moisturizing and repairing composition adopts polyglutamic acid gamma-PGA which is a main component forming natto viscous colloid and has the function of promoting mineral absorption, and at present, the gamma-PGA is listed in a health-care component table for promoting mineral absorption in Japan. The gamma-PGA has a special molecular structure, so that the gamma-PGA has extremely strong moisturizing capability, and can effectively increase the moisturizing capability of the skin and promote the health of the skin when being added into cosmetics or care products. Compared with Hyaluronic Acid (HA), the moisturizing effect of gamma-PGA exceeds 2-3 times of the effect of HA, and is a new-generation biotechnological moisturizing component.
The composite moisturizing and repairing composition adopts a biological preservative, namely polylysine, polylysine is polypeptide with a bacteriostatic effect, polylysine can be decomposed into lysine in a human body, and the lysine is one of 8 amino acids necessary for the human body and is also an amino acid allowed to be strengthened in food in countries all over the world. Therefore, the polylysine is a nutritional bacteriostatic agent, has higher safety than other chemical preservatives, and has the acute oral toxicity of 5 g/kg. Polylysine has a broad antibacterial spectrum, and can be used for treating Candida acuminata, Rhodotorula farinosa, Pichia pastoris and Sporobolomyces rosea of Saccharomyces; heat-resistant Bacillus stearothermophilus, Bacillus coagulans and Bacillus subtilis in gram-positive bacteria; the gram-negative bacteria such as the aerobacter aerogenes and the escherichia coli have obvious inhibiting and killing effects. The polylysine has obvious inhibition effect on the growth of gram-positive micrococcus, lactobacillus bulgaricus, streptococcus thermophilus, gram-negative escherichia coli, salmonella and saccharomycetes, and the polylysine and acetic acid compound reagent has obvious inhibition effect on bacillus subtilis.
The composite moisturizing and repairing composition disclosed by the invention adopts glucan. The glucan may be a plant-extracted oat glucan, or a biofermented yeast glucan, or a glucose-polymerized glucan. It mainly has the following remarkable effects: 1. improving the capability of resisting infection of viruses, bacteria and the like; 2. effectively regulating the micro-ecology of the digestive tract in vivo, and promoting the proliferation of beneficial bacteria in vivo and the excretion of harmful substances in intestinal tract; 3. can reduce cholesterol content in vivo, reduce low density lipoprotein content in vivo, and increase high density lipoprotein content; 4. effectively improving the feeling of peripheral tissues to insulin, reducing the requirement on insulin, promoting the recovery of glucose, and having obvious inhibiting and preventing effects on diabetes; 5. stimulating the activity of skin cells, enhancing the immune protection function of the skin, efficiently repairing the skin, reducing the generation of skin wrinkles and delaying the skin aging; 6. enhancing the resistance of animals to pathogenic bacteria, promoting the growth of the animals, and improving the production performance and the feed utilization rate of the animals.
The composite moisturizing and repairing composition disclosed by the invention adopts glycerin, propylene glycol and butylene glycol which are plant sources. The traditional moisturizers used most in the beauty cosmetics are glycerin, propylene glycol and butylene glycol, but the glycerin, the propylene glycol and the butylene glycol can bring fever and sticky feeling to the skin, and the moisturizing effect of the glycerin, the propylene glycol and the butylene glycol is exerted through the formula combination of the invention, so that the fever and the sticky feeling are overcome.
In the composite moisturizing and repairing composition, the peptide bi-molecular lipophilic and hydrophilic surfactant is adopted, so that the permeability and the spreadability are improved, and the effect of repairing skin and hair is achieved. The peptide bimolecular lipophilic and hydrophilic surfactant is a peptide bimolecular lipophilic and hydrophilic surfactant which is produced by Asahi Kasei corporation and has the model number of Pellicer LB-10.
The following are specific examples of the present invention, and raw materials, equipments and the like used in the following examples can be obtained by purchasing them unless otherwise specified.
Example 1:
example 2:
example 3:
example 4:
the preparation method of the composite moisturizing repair composition of the embodiments 1 to 4 comprises the following steps of weighing sodium hyaluronate, dendrobe polysaccharide, polyglutamic acid, polylysine and dextran according to a ratio, dispersing glycerol, 1,3 propanediol and 1,3 butanediol, adding the dispersed glycerol, 1,3 propanediol and 1,3 butanediol into water for dissolving, adding betaine, trehalose, erythritol and peptide bimolecular lipophilic and hydrophilic surfactant while stirring, wherein the stirring speed is 800-.
The composite moisturizing repair composition of example 1 is applied to a mask and a lotion, and the composite moisturizing repair compositions of examples 2 to 4 are applied to moisturizing repair essence, moisturizing repair essence milk or moisturizing repair essence cream, respectively, to obtain examples 5 to 9, wherein the proportions of examples 5 to 9 are as follows.
Example 5:
a facial mask containing composite moisturizing and repairing composition is prepared from phase A and phase B; wherein the phase A comprises 0.1 percent of carbomer 940, 0.2 percent of allantoin, 0.5 percent of nicotinamide and 80.65 percent of water in percentage by mass; the phase B comprises 10.0 percent of composite moisturizing and repairing composition, 0.1 percent of caprylyl hydroximic acid, 0.3 percent of p-hydroxyacetophenone, 0.05 percent of essence and 0.1 percent of triethanolamine in percentage by mass; the preparation method of the facial mask specifically comprises the following steps: mixing, stirring and heating the phase A raw materials to 80 ℃, preserving heat for 30 minutes, and homogenizing at low speed for 5 minutes; cooling to 45 deg.C, adding B phase raw material, stirring and dissolving to obtain the final product.
Example 6:
a cosmetic lotion containing composite moisturizing and repairing composition is prepared from phase C and phase D; wherein the phase C comprises 0.2% of aloe extract, 0.2% of allantoin, 0.5% of nicotinamide and 93.65% of water by mass percentage; the phase D comprises 5.0 percent of composite moisturizing and repairing composition, 0.1 percent of caprylyl hydroximic acid, 0.3 percent of p-hydroxyacetophenone and 0.05 percent of essence in percentage by mass; the preparation method of the toning lotion comprises the following steps: mixing, stirring and heating the phase C raw materials to 80 ℃ according to the proportion, preserving heat for 30 minutes, and homogenizing for 5 minutes; cooling to 45 deg.C, adding D phase raw material, stirring and dissolving to obtain the final product.
Example 7:
a moisturizing repair essence containing a composite moisturizing repair composition is prepared from an E phase and an F phase; wherein the phase E comprises 0.2 percent of carbomer 940, 0.2 percent of allantoin, 0.5 percent of nicotinamide and 48.45 percent of water in percentage by mass; the phase E comprises 50.0 percent of the compound moisturizing and repairing composition, 0.1 percent of caprylyl hydroximic acid, 0.3 percent of hydroxyacetophenone, 0.05 percent of essence and 0.2 percent of triethanolamine; the preparation method of the moisturizing and repairing essence comprises the following steps: mixing, stirring and heating the raw materials of the E phase to 80 ℃ according to the proportion, preserving heat for 30 minutes, and homogenizing at low speed for 5 minutes; cooling to 45 deg.C, adding F phase raw material, stirring and dissolving to obtain the final product.
Example 8:
a repair essence milk containing composite moisturizing repair composition is prepared from a G phase, an H phase and an I phase; wherein the G phase comprises 0.2 percent of carbomer 941, 0.2 percent of allantoin, 0.2 percent of methylparaben and 76.15 percent of water in percentage by mass; the H phase comprises 1.5 percent of stearic acid, 1.5 percent of cetearyl alcohol, 3.0 percent of squalane, 1.5 percent of glyceryl stearate, 2.0 percent of polyoxyethylene sorbitan monostearate and 3.0 percent of caprylic/capric triglyceride in percentage by mass; the phase I comprises 10.0 percent of composite moisturizing and repairing composition, 0.5 percent of phenoxyethanol, 0.05 percent of essence and 0.2 percent of triethanolamine in percentage by mass; the preparation method of the moisturizing and repairing essence milk comprises the following steps: mixing the raw materials of the G phase and the B phase respectively according to the proportion, stirring and heating to 80 ℃, preserving heat for 20 minutes, adding the H phase into the A phase under stirring, and homogenizing for 5 minutes; cooling to 45 deg.C, adding phase I raw materials, and stirring for 10 min.
Example 9:
a moisturizing repair essence cream containing a composite moisturizing repair composition is prepared from a J phase, a K phase and an L phase; wherein the J phase comprises 0.35% of carbomer 934, 0.2% of allantois, 0.2% of methylparaben and 75.85% of water in percentage by mass; the K phase comprises 1.5 percent of stearic acid, 1.5 percent of cetostearyl alcohol, 3.0 percent of squalane, 1.5 percent of glyceryl stearate, 2.0 percent of polyoxyethylene sorbitan monostearate and 3.0 percent of caprylic/capric triglyceride in percentage by mass; the L phase comprises 10.0 percent of composite moisturizing and repairing composition, 0.5 percent of phenoxyethanol, 0.05 percent of essence and 0.35 percent of triethanolamine in percentage by mass; the preparation method of the moisturizing and repairing essence cream comprises the following steps: mixing J-phase raw materials and K-phase raw materials according to a ratio, stirring and heating to 80 ℃, preserving heat for 20 minutes, adding the J-phase raw materials into the K-phase raw materials under stirring, and homogenizing for 5 minutes; cooling to 45 deg.C, adding L phase raw materials, and stirring for 10 min.
Comparative examples 1 to 4:
comparative example 1 is different from example 6 in that the composite moisturizing repair composition of example 6 is replaced with hyaluronic acid.
Comparative example 2 differs from example 6 in that the composite moisturizing repair composition of example 6 was replaced with polyglutamic acid.
Comparative example 3 is different from example 6 in that the composite moisturizing repair composition of example 6 is replaced with dendrobii polysaccharide.
Comparative example 4 is a blank solution.
Effect evaluation and Performance detection
1. Purpose of experiment
Moisturizing efficacy comparisons of example 6, comparative examples 1-4 were tested.
2. Test subject
5 women with healthy hand skin aged 20-22 years.
3. Experimental equipment
German CK skin tester Cutomer MPA 580, dry facial tissue, latex finger stall, 10-100 μ L of liquid-transfering gun.
4. Experimental methods
4.1 preparation before testing
(1) Any product (cosmetics and external medicines) can not be used for 2-3 days before the test of the tested part, and water can not be contacted for 1-3 hours. Before the test, the testee needs to uniformly clean the inner sides of the forearms of the hands, and the cleaning method is to wipe the forearms clean by using dry facial tissues.
(2) Before formal test, sitting still in a room meeting the standard for at least 20min, no drinking water or beverage, exposing forearm, and placing in the test state to keep relaxed.
4.2 determination
(3) And starting a laboratory air conditioner at 7:00 in the morning, setting the temperature to be 20 ℃, after one hour, allowing the testee to enter the laboratory after the temperature and the humidity are stable, resting for 20min, determining the tested area of the testee during the resting period, and preparing for cleaning. Subjects were tested at 8:20, 10:20, 12:20, 14:20, 16:20, 18:20, 20:20, respectively, and entered the test laboratory for resting 20 minutes prior to testing.
(4) The product application zone and blank control zone should be randomly distributed over the left and right arm calibration zones to ensure that all product and blank zone positions are statistically balanced.
(5) The test sample was coated in a single pass at a dose of 0.02g, the sample was evenly coated into the test area using a latex finger cot, and the actual amount of sample coating was recorded.
(6) After the instruments are adjusted according to the instructions of a capacitance method skin moisture tester and an epidermis moisture loss tester, the product area and the control area are measured, and each area is tested at least three times in parallel. The initial values for each test area (before sample application) were measured and the test was performed every 2h after sample and reference application for 12 h.
5. Results and discussion
5.1 data on the stratum corneum content of the epidermis are shown in Table 1, and FIG. 1.
TABLE 1 variation of the mean content of the stratum corneum of the skin
| Product application time | Comparative example 1 | Example 6 | Comparative example 2 | Comparative example 3 | Comparative example 4 |
| Before applying the product | 37.976 | 41.192 | 41.08 | 42.508 | 42.744 |
| After 10min | 36.824 | 66.88 | 37.16 | 43.072 | 41.208 |
| After 2h | 40.464 | 61.74 | 42.076 | 43.2 | 41.86 |
| After 4 hours | 39.144 | 60.384 | 39.168 | 44.76 | 43.484 |
| After 6 hours | 42.824 | 59.716 | 42.596 | 46.988 | 45.68 |
| After 8 hours | 40.668 | 59.776 | 42.936 | 46.876 | 44.664 |
| After 10 hours | 40.712 | 60.416 | 45.612 | 47.186 | 44.492 |
| After 12h | 41.268 | 58.024 | 41.416 | 44.636 | 44.172 |
As can be seen from Table 1 and FIG. 1, the water content of the horny layer of example 6 is much higher than that of comparative examples 1 to 4.
5.2 mean values of TEWL (normal value of skin transepidermal water loss) of skin after application of different samples are shown in Table 2, and FIG. 2.
TABLE 2 TEWL in skin after application of no sample
As can be seen from Table 2 and FIG. 2, the TEWL of the skin of example 6 was much lower than that of comparative examples 1-4 after the samples of example 6 and comparative examples 1-4 were applied.
As can be seen from tables 1 to 2 and fig. 1 to 2, the moisturizing lotion containing the composite moisturizing repair composition of the present invention has a high water content and a low water loss of the stratum corneum after use, which indicates that the moisturizing performance of the moisturizing lotion containing the composite moisturizing repair composition of the present invention is good, and compared with comparative examples 1 to 3, the composite moisturizing repair composition overcomes the disadvantages of a single moisturizing raw material and a repair raw material, and achieves the moisturizing and repair effects that cannot be achieved by a single raw material.
The above embodiments are only preferred embodiments of the present invention, and the protection scope of the present invention is not limited thereby, and any insubstantial changes and substitutions made by those skilled in the art based on the present invention are within the protection scope of the present invention.
Claims (3)
1. The composite moisturizing and repairing composition is characterized by being prepared from the following components in percentage by mass:
0.1 to 15 percent of sodium hyaluronate
Dendrobium polysaccharide 0.1-5.0%
0.1 to 0.5 percent of tremella heteropolysaccharide
0.1 to 1.0 percent of polyglutamic acid
0.1 to 0.5 percent of polylysine
Betaine 0.1-3%
Trehalose 0.1-3%
Erythritol 0.1-3%
Dextran 0.1-0.6%
Peptide bimolecular lipophilic and hydrophilic surfactant 0.1-0.6%
1% -20% of glycerin
1, 3-propylene glycol 1% -15%
1 to 10 percent of 1, 3-butanediol
The balance of water;
the sum of the mass percentages of the components is 100 percent;
the peptide bimolecular lipophilic and hydrophilic surfactant is Pellicor LB-10 peptide bimolecular lipophilic and hydrophilic surfactant.
2. The composite moisturizing repair composition of claim 1, wherein the sodium hyaluronate is one or more of sodium hyaluronate A, sodium hyaluronate B, sodium hyaluronate C, sodium hyaluronate D, sodium hyaluronate E, sodium hyaluronate F, and sodium hyaluronate G; wherein the molecular weight of the sodium hyaluronate A is more than 200 ten thousand, the molecular weight of the sodium hyaluronate B is 150-190 ten thousand, the molecular weight of the sodium hyaluronate C is 150-150 ten thousand, the molecular weight of the sodium hyaluronate D is 50-100 ten thousand, the molecular weight of the sodium hyaluronate E is 10-50 ten thousand, the molecular weight of the sodium hyaluronate F is 1-10 ten thousand, and the molecular weight of the sodium hyaluronate G is 1-1 ten thousand.
3. Use of the composite moisturizing repair composition of claim 1 or 2 in the preparation of a mask, a lotion, a moisturizing repair essence cream, or a moisturizing repair essence cream.
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| CN111053726A (en) * | 2019-12-02 | 2020-04-24 | 广州市京妍生物科技有限公司 | Skin care product containing multiple extracts and preparation method thereof |
| CN111437209A (en) * | 2020-04-26 | 2020-07-24 | 华熙生物科技股份有限公司 | Self-luminous photon skin-tendering hyaluronic acid moisturizing mask |
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| WO2014076136A1 (en) * | 2012-11-13 | 2014-05-22 | Galderma S.A. | Bpo wash emulsion composition |
| CN105640796A (en) * | 2016-01-13 | 2016-06-08 | 中山爱护日用品有限公司 | Composition with high moisture retention performance and application of composition to infant cream |
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| WO2014076136A1 (en) * | 2012-11-13 | 2014-05-22 | Galderma S.A. | Bpo wash emulsion composition |
| CN105640796A (en) * | 2016-01-13 | 2016-06-08 | 中山爱护日用品有限公司 | Composition with high moisture retention performance and application of composition to infant cream |
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