Summary of the invention
The present invention is for making up the deficiencies in the prior art, it is provided that a kind of have good skin care item containing multiple honeycomb active component of good moistening effect, safety and skinfeel and preparation method thereof.
The present invention, for reaching its purpose, adopts technical scheme as follows:
A kind of skin care item containing multiple honeycomb active component, containing weight/mass percentage composition in described skin care item is the honeycomb compositions of 1~3%, and described honeycomb compositions includes each component of following mass parts: Mel extract 10~40 parts, Lac regis apis 10~40 parts, Mel 10~40 parts, propolis extract 10~40 parts.
Possibly together with each component that weight/mass percentage composition is following in described skin care item: 2-Methylpentadecane 3.0%~5.0%, IPIS 1.0%~5.0%, isooctadecanol isostearate 1.0%~3.0%, methyl sesquistearate 1.0%~1.5%, caprylic/capric triglyceride 1.0%~6.0%, butanediol 2.0%~8.0%, PEG-20 methyl sesquistearate 0.8%~1.5%, xanthan gum 0.02%~0.3%, glucosan 0.5%~3.0%, pantothenylol 0.5%~3.0%, bisabolol 0.1%~0.5%.
Possibly together with coloring agent 2%~8% in described skin care item.Further, described coloring agent is specially in foundation product to be allowed the coloring agent used, for instance for titanium dioxide, CI77491, CI77499, CI77492 etc..As a kind of detailed description of the invention, coloring agent is made up of each component that the weight/mass percentage composition in skin care item is following: titanium dioxide 2.0%~7.0%, CI774910.02%~0.3%, CI774990.02%~0.2%, CI774920.02%~0.3%.
Possibly together with preservative 0.1%~0.8% in described skin care item.
Described preservative be phenethanol and 2,4-dybenal.
Described phenethanol and 2,4-dybenal weight/mass percentage composition in skin care item respectively 0.1%~0.5%, 0.1%~0.3%.
Described skin care item are foundation cream.
Described skin care item are made up of each component of following weight/mass percentage composition: the honeycomb compositions of 1~3%, 2-Methylpentadecane 3.0%~5.0%, IPIS 1.0%~5.0%, isooctadecanol isostearate 1.0%~3.0%, methyl sesquistearate 1.0%~1.5%, caprylic/capric triglyceride 1.0%~6.0%, butanediol 2.0%~8.0%, PEG-20 methyl sesquistearate 0.8%~1.5%, xanthan gum 0.02%~0.3%, glucosan 0.5%~3.0%, pantothenylol 0.5%~3.0%, bisabolol 0.1%~0.5%, coloring agent 2%~8%, preservative 0.1~0.8%, the water of surplus.
The preparation method that the present invention also provides for a kind of skin care item containing multiple honeycomb active component mentioned above, comprises the steps:
1) each component is weighed according to formula, described formula includes each component of following weight/mass percentage composition: the honeycomb compositions of 1~3%, 2-Methylpentadecane 3.0%~5.0%, IPIS 1.0%~5.0%, isooctadecanol isostearate 1.0%~3.0%, methyl sesquistearate 1.0%~1.5%, caprylic/capric triglyceride 1.0%~6.0%, butanediol 2.0%~8.0%, PEG-20 methyl sesquistearate 0.8%~1.5%, xanthan gum 0.02%~0.3%, glucosan 0.5%~3.0%, pantothenylol 0.5%~3.0%, bisabolol 0.1%~0.5%, coloring agent 2%~8%, preservative 0.1~0.8%, the water of surplus;
2) xanthan gum is used butanediol moistening, be subsequently adding in aqueous phase pot, stirring, add PEG-20 methyl sesquistearate, water, be warming up to 75~85 DEG C, insulation, until being completely dissolved, standby as B phase;
3) by step 2) gained B phase sucked in emulsifying pot by vacuum, homogenizing;
4) coloring agent, 2-Methylpentadecane, IPIS, isooctadecanol isostearate, methyl sesquistearate, caprylic/capric triglyceride are sequentially added in oil phase pot, it is then heated to 75~85 DEG C, as A phase, then A phase is sucked in emulsifying pot by vacuum, stirring, homogenizing, be cooled to 40~50 DEG C;
5) glucosan, pantothenylol are added in emulsifying pot, stir, be subsequently adding remaining components, continue stirring;
6) less than 38 DEG C it are cooled to, discharging.
Technical scheme provided by the invention has the advantages that
In skin care item provided by the invention, containing the honeycomb compositions being made up of according to specific proportioning Mel extract, Lac regis apis, Mel, propolis extract, each component interaction in this honeycomb compositions, Synergistic, skin played moisturizing, antiinflammatory, releive, antibacterial effect, and natural origin, safe, without any side effects.Moisture of skin regulatory function can be improved on the one hand, provide good moistening effect for keratodermatitis, increase skin elasticity and flexibility;Antibiotic anti-infection can be played on the other hand, play the effect of antiinflammatory.
Several the components description below skin care item of the present invention added are as follows:
Mel extract, its chemical composition contains abundant aminoacid, polysaccharide liquid, lactic acid, carbamide etc..The Mel extract added in the skin care item of the present invention can pass through market and buy acquisition, and that adopt in the embodiment of the present invention is the BIO-HYDRACTYL (Mel extract) of Cobiosa company of Spain.
Lac regis apis, has another name called Lac regis apis, Lac regis apis breast, queen bee breast, Lac regis apis, is the secretions of the young worker bee pharynx gland cultivating larva in honeycomb, is supplied with becoming the food of the larva of queen bee, be also the lifelong food of queen bee.Bought by market and obtain.Containing multivitamin, sugar, protein, lipid, mineral.In the prior art, Lac regis apis can be prepared as follows: producing Lac regis apis should carry out by 48~72h after moving worm, checks and produces slurry group, and as wax cup is made into Nidus Vespae by worker bee, larva therein also grows up, can be with slurry.Take slurry to carry out in the indoor of cleaning, wear working clothing, wear masks.First take off each section of lath, remove larva with pincet, then dig out Lac regis apis, be immediately placed in amber glass bottle, airtight, deepfreeze.Superoxide dismutase (SOD) in Lac regis apis is antioxidative main component.Reparation and the regeneration of cell are had very strong effect by it, and Lac regis apis has antibacterial and wound infection has the effect promoting healing.Test shows, the antimicrobial spectrum of Lac regis apis is escherichia coli, Staphylococcus aureus Bacillus typhi, streptococcus, Bacillus proteus, bacillus subtilis, tubercule bacillus, starlike Trichophyton and epidermophyton etc..Lac regis apis, containing proteohormone and natural antibiotics, is smeared and can be played the effect preventing infecting, promote Hemapoiesis, rear preventing from scar when treatment is scalded.The embodiment of the present invention uses the ACNACIDOL (Lac regis apis) that Vincience company of France provides.
Mel: the nectar that to be Apis adopt from the spending of flowering plant.Nectar or the secretions that Apis takes water content to be about 75% from the spending of plant, it contains substantial amounts of sugar part, aminoacid, several mineral materials etc..The gram positive bacterias such as streptococcus, staphylococcus, diphtheria are had stronger inhibitory action by Mel, when processing wound, can reduce and ooze out, ease the pain, promote wound healing, it is prevented that infect, wound surface has convergence, Nutrition.Mel in Example formulations is provided by Hong Xiang bio tech ltd, Shanghai.
Propolis extract: its chemical composition mainly has flavonoid, phenols, lactone, Coumarins, aldehyde, ketone, steroid, possibly together with vitamin B1, nicotinic acid, provitamin A and several amino acids, sugar, polysaccharide and indispensable element 34 kinds (oxygen, carbon, hydrogen, calcium, phosphorus, nitrogen, potassium, sulfur, sodium, chlorine, magnesium, ferrum, cobalt, copper, molybdenum, fluorine, aluminum etc.).
Preferably, the propolis extract of the present invention is prepared according to the method comprised the steps:
1) acetic acid ethyl dissolution of 1-3 times of quality of propolis is obtained extractum, stand 3-6 hour;It is raw material that propolis used preferably employs fresh propolis
2) to step 1) described in extractum in add 0.5~2 times of quality the NaHCO that mass concentration is 4~6%3Aqueous solution extracts 2-5 hour at normal temperatures;
3) by hcl acidifying step 2) extracting solution of gained so that it is pH is 3-5;The ether adding 1~3 times of quality in the solution after acidified extracts 3-5 hour at normal temperatures, obtains ether extracted liquid;
4) to step 3) ethyl acetate that adds 1~2 times of quality in gained ether extracted liquid extracts 1-2 hour at normal temperatures, obtains acetic acid ethyl acetate extract;
5) by step 4) gained acetic acid ethyl acetate extract under 80-90 DEG C of water bath condition with Rotary Evaporators concentrate, gained concentrate drying obtains propolis extract.
In the market but without this foundation product containing 4 kinds of honeybee active components of the present invention occurs.Foundation product provided by the invention adds novel honeycomb compositions, even if under relatively low addition, also can show good effect.Test result shows, the foundation product safety that the present invention is added with this compositions is high, moistening effect is good, there is skinfeel as snug as a bug in a rug simultaneously, this product does not singly have multiple skin-care effect, also there is the effect hiding the flaw, skin care, integrate nutrition, moisturizing, resist ultraviolet, isolate the effects such as dirty air, be a kind of novel product with good market application foreground.
The foundation cream adopting technical solution of the present invention to prepare, has well patch skin and safety.This foundation cream moistening effect being added with cellular-specific compositions is more preferably, antiinflammatory is functional, antibacterial ability is also significantly improved.This series products is highly suitable for child and sensitivity skin, has significantly widened the range of application of product.
Compared with present propolis product, present invention uses the honeycomb compositions of specific composition, prepared foundation cream moisturizing, antiinflammatory, skin and complexion improving, releive etc. in show the performance of excellence.Compared with common foundation product, the patch skin of foundation cream prepared by the formula of the present invention, moisturizing degree, antibacterial effect is adopted to be obtained for and be obviously improved.The foundation product of the present invention has following feature:
1) with the addition of the foundation product of the specific honeycomb compositions of the present invention, containing the substantial amounts of composition to skin beneficiating, such as proteins,vitamins,minerals and trace element, functional abundanter.
2) compared with common wetting agent, honeycomb compositions has the moisture-keeping efficacy become apparent from, and under low-down addition, product shows the moistening effect of excellence.
3) it is gentleer, has the safety of height, is applicable to sensitive skin crowd and infant, has widened the Sales Channel of product.
4) serviceability of foundation emulsion product gets a promotion, and with the addition of the foundation product of honeycomb compositions of the present invention, and its patch skin is obviously improved, and the skinfeel smeared also is significantly improved, and moistens with rear skin emolliency.
5) the multiple antibacterial composition contained in honeycomb compositions, these compositions have the effect of Synergistic, it is possible to greatly reducing the consumption of preservative in formula, the safety of product is also further promoted.
Propolis extract used in embodiment 1-3 all adopts following steps to prepare:
1) the propolis acetic acid ethyl dissolution of 2 times of quality is obtained extractum, stand 4 hours;Propolis used adopts fresh propolis to be raw material;
2) to step 1) extractum in add 1 times of quality the NaHCO that mass concentration is 5%3Aqueous solution extracts 4 hours at normal temperatures;
3) by hcl acidifying step 2) extracting solution of gained so that it is pH is 4;The ether adding 2 times of quality in the solution after acidified extracts 5 hours at normal temperatures, obtains ether extracted liquid;
4) to step 3) ethyl acetate that adds 1 times of quality in gained ether extracted liquid extracts 2 hours at normal temperatures, obtains acetic acid ethyl acetate extract;
5) by step 4) gained acetic acid ethyl acetate extract under 90 DEG C of water bath condition with Rotary Evaporators concentrate, gained concentrate drying obtains propolis extract.
Reference examples
Formula shown in table 1 below weighs each raw material of reference examples, prepares the foundation product of reference examples referring next to the preparation method of embodiment 1-3.
Table 1
Table 2
Product checking
One, moisture-keeping efficacy evaluation
Method of testing: the trier to the product using embodiment 2 and reference examples, has carried out the test and comparison of human keratinous layer electrical conductivity, and electrical conductivity increase represents the moisturizing degree of skin to be increased.Before testing use respectively, use the horny layer electrical conductivity after 30 minutes, after 1 hour, after 2 hours and after 4 hours.
Test condition: horny layer is separated and places it in a runner plate, this indoor conditions be adjusted 20 DEG C~25 DEG C, in the relative humidity conditions of 44%~60%.
Test result is referring to shown in Fig. 1 and table 3 below.By testing result it can be seen that embodiment 2 is compared with reference examples, moistening effect has to compare and is obviously improved, and uses 2 hours, and electric conductivity increases by 50~60%, and the moisturizing degree that represent product increases by 50~60%.Embodiment 1,3 has been also carried out this test, and its result and embodiment 2 are essentially identical, repeat no more.
Table 3
Two, human skin patch
Evaluation methodology:
1.1 tested materials: the product of embodiment 1~3, and commercially available Korea S famous brand name propolis BB frost (matched group).
1.2 negative controls: blank.
1.3 experimenters: totally 25 people, male 12 people, female 13 people, at 18~30 years old age, meet experimenter and volunteer inclusion criteria.
Speckle method for testing: select speckle examination device, with closed patch test method, tested material is about 0.02ml~0.025ml and is applied in speckle examination device, external special adhesive tape is pasted on experimenter's forearm song side, tested material is removed after 24 hours, 30min after removing tested material speckle examination device, observes dermoreaction after impression disappears, records its result by dermoreaction grade scale in " cosmetics health specification " (version in 2007).
1.4 evaluation of result: record reaction result by table 4 (skin adverse reaction grade scale).
Table 4
1.5 result of the tests: in Table 5.
Table 5: cosmetics human skin patch result
Remarks: matched group is commercially available Korea S famous brand name propolis BB frost.
Result above shows: in embodiment 1,2,3, and 25 subjects skin are all negative reaction (grading system: 0 grade).According to " cosmetics health specification " (version in 2007) human body skin class patch test criterion, sample is to human body without skin adverse reaction, and embodiment all has good safety.Matched group has 2 example 1 order reactions, although have also passed through test, but safety is not good enough.
Three, organoleptic analysis's assessment
Appraisal procedure:
1) tested material: the cosmetics finished product of embodiment 1~3 and reference examples.
2) experimenter: totally 30 people, male 10 people, female 20 people, at 21~49 years old age, meet experimenter and volunteer inclusion criteria.
3) appraisal procedure: the sample of 0.3 gram is applied to the back of the hand, mildly convolution smears 8 times, then by marking in the way of (0~10 point, mark is more high, represent the texture of this product, spreadability, soft and smooth degree, patch skin, more good by rear comfort), the score value of these 5 indexs is added, and numerical value is more high, illustrates that properties of product are more good.
Table 6
Sample |
Texture |
Spreadability |
Soft and smooth degree |
Patch skin |
Comfort |
Total score |
Embodiment 1 |
8.0 |
8.7 |
9.2 |
9.0 |
9.3 |
44.2 |
Embodiment 2 |
8.6 |
8.0 |
8.8 |
9.0 |
9.2 |
43.6 |
Embodiment 3 |
8.2 |
8.8 |
8.5 |
8.5 |
8.8 |
42.8 |
Reference examples |
8.1 |
7.7 |
8.0 |
8.2 |
8.1 |
40.1 |
Assessment result: being coated with and add up with rear comprehensive experimenter scoring, result is as shown in table 6, and result shows, the foundation product of embodiment 1-3, uses rear skin smooth, and soft, skinfeel is comfortable, and effect is more preferably.
The above, it it is only presently preferred embodiments of the present invention, not the present invention is done any pro forma restriction, therefore all contents without departing from technical solution of the present invention, the technical spirit of the foundation present invention, to any simple modification made for any of the above embodiments, equivalent variations and modification, all still falls within the scope of technical solution of the present invention.