CN110037952A - A kind of crease-resistant and Vitamin K eye mask patch - Google Patents
A kind of crease-resistant and Vitamin K eye mask patch Download PDFInfo
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- CN110037952A CN110037952A CN201910281904.9A CN201910281904A CN110037952A CN 110037952 A CN110037952 A CN 110037952A CN 201910281904 A CN201910281904 A CN 201910281904A CN 110037952 A CN110037952 A CN 110037952A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
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Abstract
The invention discloses a kind of crease-resistant and Vitamin K eye mask patches, mainly contain following components: horse chestnut extract, glucityl aurantiamarin, peony root extractive.Utilize palmityl tripeptides -5 and both small active peptides of carnosine and micromolecule hyaluronic acid, it can promote the effect that collagen and elastic fibers generate in dermal layer of the skin, reach and improve skin water humidity, improve skin elasticity, reduce wrinkle of skin, the effect of anti-aging；It is arranged in pairs or groups with horse chestnut extract, glucityl aurantiamarin, peony root extractive these three plant extracts, promotes the blood circulation of eye, improve the color of eye part skin, Vitamin K, the effect of enhancing product desalination microgroove, free radical resisting；The characteristics of using anion efficient corrosion resisting and low stimulation, promotes the mildness of eye mask patch and uses comfort.
Description
Technical field
The present invention relates to cosmetic fields, are specifically related to a kind of crease-resistant and Vitamin K eye mask patch.
Background technique
Periocualr skin is the place for being easiest to aging in human skin and leading to the problem of.Skin histology around eyes is very
Soft and fine slim, sweat gland and the sebaceous glands distribution of periocualr skin are less, are particularly easy to dry water shortage, while people in present life
The dependence of the electronic equipments such as the mechanical, electrical brain of opponent, plate is increasing, faces these LCD screens for a long time, eyes can be made to produce
Raw fatigue, can also aggravate the burden of eye skin care.It is influenced, is dissociated in skin with advancing age and by environmental stimuli
Free radical is more and more, and free radical destroys collagen, active material in normal cell membrane tissue, makes glue in dermal layer of the skin
The speed that former albumen and elastic fibers generate is unable to catch up with the speed being lost, and loses mesh-supported power, Elastic fibers and glue
Fibrinogen changes and gradually loses skin elasticity and tension, and small microgroove, wrinkle etc. occurs in eye circumference, causes eye skin relaxation, skin
Skin starts evidence for senescence occur.
It is also to annoying another problem of many people that black eye, which occurs, in eye.Regular stays up late, mood swing, with eye
Excessively, sleep insufficiency causes meeting eye part skin vascular flow speed excessively slow, so that forming viscous flow forms black eye, this is common
In many young men；In addition, metabolic waste accumulation is excessive in blood vessel, and chromogenesis is calm since skin histology is for hypoxgia, and
It is emerging on upper and lower eyelid, one layer of black circle occurs, age bigger people, the subcutaneous fat around eyes becomes thinner, black eye
Also it can become apparent from.
Eye mask patch is similar with mask sheet, and Essence is pasted using film cloth as carrier relative to other eye-care product, eye mask
Skin liquid absorption amount is big, and when use is temporarily isolating extraneous air and pollution, improves eye skin temperature, the pore expansion of skin,
Promote sweat gland, secretion and metabolism, active constituent is made to be easier to enter the cuticula of skin, to play more significant skin care
Effect.Eyeware products and solution for lenses and contact lenses in the market is many kinds of, and the eye mask patch for having both Vitamin K and crease-resistant effect is seldom, and
Effect is not to have certain mobility, when use has been easy few it is obvious that simultaneously because eye mask patch Essence consistency is lower
Amount Essence flows into eye accidentally, causes the sense of discomfort of eyes, and the preservative that Form aldehyde release body, Phenoxyethanol etc. are traditional,
Eyes are had with certain irritation.
Summary of the invention
It can effectively keep the skin wet the technical problem to be solved in the present invention is to provide a kind of, remove eye wrinkle-removing, improve eye
Skin elasticity delays eye part skin aging, improves periocualr skin color, and the crease-resistant and Vitamin K non-stimulated to eyes
Eye mask patch and preparation method thereof.
To achieve the goals above, the present invention adopts the following technical scheme:
A kind of eye mask patch, mainly contains the component of following weight percentage:
Horse chestnut extract 0.2~1%,
Glucityl aurantiamarin 0.1~1%,
Peony root extractive 0.5~3%.
In wherein some embodiments, the eye mask patch also contains the component of following weight percentage:
1 ‰ -5 aqueous solution 1~5% of palmityl tripeptides,
Carnosine 0.1~0.5%,
Micromolecule hyaluronic acid sodium 0.1~0.3%.
Further, eye mask patch of the present invention, also contains the component of following weight percentage:
Moisturizer 4.5-13%,
Preservative 0.2-0.5%,
Rheology modifiers 0.15-0.45%.
In wherein some embodiments, the moisturizer by 1,3-PD, glycerol, betaine group at, described 1,
3-propanediol, glycerol, glycine betaine mass ratio be (2-5): (2-5): (1-3).
In wherein some embodiments, the preservative is silver ion antimicrobial agent, and the silver ion antimicrobial agent adds
Dosage is 0.3-0.4wt%.
In wherein some embodiments, the rheology modifiers are carbomer.
In wherein some embodiments, dipotassium glycyrrhizinate, the dipotassium glycyrrhizinate can also be added in the eye mask patch
Additive amount be 0.1~0.5wt%.
The embodiment of the invention also provides the preparation methods of eye mask patch, comprising the following steps:
(1) 1,3- propylene glycol, glycerol, carbomer, micromolecule hyaluronic acid sodium and purified water are mixed and is added in the ratio
Heat is to 85~90 DEG C, and homogeneous 10 minutes, insulated and stirred started to cool down after 30 minutes；
(2) when being cooled to 45 DEG C, sequentially add glycine betaine, horse chestnut extract, glucityl aurantiamarin, dipotassium glycyrrhizinate, carnosine,
Palmityl tripeptides -5 and peony root extractive, stir evenly；
(3) silver ion preservative is added after above-mentioned raw materials are completely dispersed uniformly, stirring to room temperature discharges after detection is qualified.
Further, the preparation method of eye mask patch further includes step (4): eye mask patch Essence is poured into containing film
In the packaging material of cloth, sealing obtains a kind of eye mask patch.
The material of film cloth of the present invention can be non-woven fabrics, biological fibrous material, pectin fiber cloth, silk fiber cloth
In any one.
Technical solution provided in an embodiment of the present invention has the benefit that
(1) anti crease and anti senile old eye mask patch of the invention, wherein anti crease and anti senile old eye mask Essence can be by palmityl tripeptides -5, flesh
The substances such as peptide, horse chestnut extract, glucityl aurantiamarin, micromolecule hyaluronic acid sodium, peony root extractive, silver ion antimicrobial agent
It is reasonably combined to form；
(2) preferred palmityl tripeptides -5 and carnosine belong to small active peptides, and small-molecular peptides can be easier that skin is allowed to absorb, and
Micromolecule hyaluronic acid sodium energy skin permeation skin corium send out skin-care effect, they are applied in combination, can promote skin collagen and
The synthesis of hyaluronic acid improves skin water humidity, improves skin elasticity, reduces wrinkle of skin, delays senescence；
(3) preferred horse chestnut extract, three kinds of glucityl aurantiamarin, peony root extractive natural plant extracts, horse chestnut
Extract is excellent Red blood streak dispelling ingredient, eye pouch significant effect of dispelling, and glucityl aurantiamarin can promote the blood circulation of skin, change
The color of kind eye part skin, Vitamin K, peony root extractive have the effect of thering is very much bright color, antiallergic, free radical resisting；
(4) eye mask Essence is free of traditional preservatives, essence etc. to eyes there may be the substance of stimulation, avoids using eye mask
When patch, because of Essence pleasing to the eye bring sense of discomfort accidentally.The organic collocation of these active materials, it is synergistic, provide a kind of tool
There is the eye mask patch that fine crease-resistant, Vitamin K effect safety is mild.
Detailed description of the invention
The skin elasticity R2 value curve graph of Fig. 1, embodiment 3.
The wrinkle of skin score value curve graph of Fig. 2, embodiment 3.
Specific embodiment
To make the object, technical solutions and advantages of the present invention clearer, embodiment of the present invention will be made into one below
Step ground detailed description, embodiments of the present invention are not limited thereto, for not specifically specified technological parameter or condition, can refer to
Routine techniques carries out.
Part material according to the present invention is described as follows:
Palmityl tripeptides -5 used in the present invention are a kind of small molecule tripeptides for possessing unique sequence, and peptide is made of amino acid,
Amino acid is similarly the chief component of all living cells including Skin Cell, and palmityl tripeptides -5 can simulate people
Body self mechanism generates collagen, increases collagen significantly and protecteds from degradation, wrinkles to caused by various agings
Line all has good effect.
The carnosine that the present invention uses in the present invention, it is one that standard Chinese title: carnosine, natural equivalent, which are present in human body,
The small active peptides of kind high-purity, it can prevent the oxidative damage of Skin Cell, inhibit glycosylation, while stimulating glue
The synthesis of former albumen, thus the effect of reaching delay skin aging.
Horse chestnut extract used in the present invention, cosmetic standard Chinese: horse chestnut (AESCULUS
CHINENSIS) extract, the main active substances in horse chestnut extract are Aescin, and Aescin is generally acknowledged plant
The excellent Red blood streak dispelling ingredient in source has and promotes skin microcirculation, and eye pouch of dispelling is dispelled the effect of ocular edema, while its energy
The synthesis for promoting skin hyaluronic acid, keeps skin close and flexible, reduces the generation of wrinkle.
Glucityl aurantiamarin used in the present invention is a kind of innovation active bio flavones from orange peel, it is
The substance that hesperidin in orange peel is bundled in cornstarch glucose and is formed, solves that hesperidin is water-soluble bad to ask
It inscribes, the active constituent in orange peel can accelerate skin metabolism by the blood circulation of promotion skin, so that it is black to reach desalination
Eyelet, eye pouch of dispelling, the effect for improving skin color.
Micromolecule hyaluronic acid sodium used in the present invention, standard Chinese title: hydrolysis Sodium Hyaluronate, is a kind of ideal
Natural moisturizing factor, molecular weight can promote into fiber finer with rapid osmotic skin, deep layer water lock less than 10000 dalton
The increment and differentiation of born of the same parents has the effect of impaired skin of maintenance, increase skin elasticity, reduction wrinkle, firm skin.
Peony root extractive used in the present invention, cosmetic standard Chinese: tree peony (PAEONIA
SUFFRUTICOSA) root extract, main active are as follows: cortex moutan original, paeonol, Paeoniflorin, tannic acid etc. have brilliance
Antiallergic, anti-inflammatory, itching-relieving action, while it can prevent cutis laxa, anti-oxidant, crease-resistant effect.
Silver ion antimicrobial agent used in the present invention, active matter content are as follows: 3000PPM, standard Chinese title: silver.Silver
Ion antibacterial agent is a kind of nontoxic, tasteless and nonirritant, free of contamination " green bactericide product ", not the nano-carrier of nano silver
Residual does not use rear residual component bring carrying capacity of environment, is widely used in modern medicine, in every-day medical, in order to anti-
Only newborn's gonococcal infection commonly uses the silver nitrate eye drip of 1% concentration.Certain density silver ion is to bacterium, virus, fungi etc.
There is killing effect, using ideal antisepsis in cosmetics, can be played, and also it is extremely low to the irritation of eyes.Suitably
Silver ion antimicrobial agent can be the AGS-WSM3000C product from Japanese Kotobuki company.
Embodiment 1
A kind of crease-resistant and Vitamin K eye mask patch, each component including following mass percentage:
The preparation method of above-mentioned crease-resistant and Vitamin K eye mask patch, comprising the following steps:
(1) 1,3- propylene glycol, glycerol, carbomer, micromolecule hyaluronic acid sodium and purified water are mixed and are added in the ratio by
Heat is to 85~90 DEG C, and homogeneous 10 minutes, insulated and stirred started to cool down after 30 minutes；
(2) when is cooled to 45 DEG C, glycine betaine, horse chestnut extract, glucityl aurantiamarin, dipotassium glycyrrhizinate, flesh are sequentially added
Peptide, 1 ‰ -5 aqueous solution of palmityl tripeptides and peony root extractive, stir evenly.
(3) silver ion is added after above-mentioned raw materials are completely dispersed uniformly, stirring to room temperature is eventually adding triethanolamine adjusting
PH to 5.5-7 discharges after detection is qualified, obtains eye mask and pastes Essence；
(4) crease-resistant and Vitamin K eye mask patch Essence being poured into the packaging material containing film cloth, Essence is adsorbed on film cloth,
Sealing obtains crease-resistant and Vitamin K eye mask patch.
Test the test of 1 preservation challenge
The Essence that the crease-resistant and Vitamin K eye mask of above-described embodiment 1-5 is pasted, according to the U.S. CTFA(cosmetics, washing
Articles and essence association) anti-corrosion single challenge test method, carry out preservation challenge experiment, obtain experimental data such as table 2-3:
The anti-corrosion of 2 embodiment 1-3 of table chooses data
The anti-corrosion of 3 embodiment 4-5 of table chooses data
From upper table 2-3 as it can be seen that the protective system of Samples EXAMPLE 1- embodiment 5 shows as outstanding, preservation challenge can be passed through
Property test.
Test the test of 2 irritations
Irritation test application is chick chorioallantoic membrane blood vessel test (CAMVA), and the test of chick chorioallantoic membrane blood vessel is
A kind of in-vitro method of eye irritant test, for assessing subject to the stimulation degree of eye.
Test method: by using the fertilization chicken embryo for having hatched 10-12 days embryo ages as laboratory sample, fertilization chicken embryo is utilized
Complete, the obvious and transparent feature of chorioallantoic membrane vascular system is black by the crease-resistant of a certain amount of above-described embodiment 1-5 and desalination
Eyelet eye mask patch Essence is contacted with chick chorioallantoic membrane, and effect observes chorioallantoic membrane injury of blood vessel after a period of time, to different
Injury of blood vessel degree scores, and is quantified irritation by vascular effect, objectively embodies reaction of the eyes to stimulation.According to
Scoring is made in the vascular reaction of chick chorioallantoic membrane, and each sample does 10 pieces of chicken embryos, records the irritation score value of sample, adopts
Experimental data is screened with Q value method of inspection, calculates weighted average, which is NC value (normal use
Concentration values).
4 irritation test data of table
As seen from Table 4, Samples EXAMPLE 1-5 Essence is in CAMVA, 0 < NC≤2, show as stress sexual stimulus, belong to nothing
Destructive stimulus, capillary does not have bleeding lesions at this time.Illustrate test sample as mild as a dove, it is very low to the stimulation of eyes,
Essence flows into eyes accidentally, will not generate sense of discomfort.
Test the test of 3 skin wrinkle resistings and skin elasticity test
Test equipment: VISIA face-image analysis system (Canfield company, the U.S.), skin elasticity tester MPA580
(CK company, Germany).
Test method: choose 50 ages between 30-65 year old, eye part skin is loose and has the health of fine wrinkles phenomenon
Volunteer, one group of 10 people of volunteer, the anti crease and anti senile old eye mask patch of above-described embodiment 1-5 of every group of volunteer application a kind of, two
It is used once, and continuous 8 weeks.Periodically taken pictures to subject's face using VISIA face-image analysis system (front, left,
45 degree of right side direction), wrinkle score value and texture score value are extracted, is averaged, the anti-wrinkle effect of Lai Tixian sample；Using skin bullet
Property tester measurement right and left eyes tail and skin elasticity now, calculate the average value for taking R2, R2=Ua/Uf, wherein Ua is from cancellation
Recovery value of the negative pressure to skin when follow-on test skin surface adds negative pressure again next time;Uf is skin maximum tension when having negative pressure
Amount.Test number such as the following table 5.
Table 5 is crease-resistant and skin elasticity evaluates data
From 5 test data of table and Fig. 1, Fig. 2: after the crease-resistant and Vitamin K eye mask patch of embodiment 1-5, volunteer
Skin elasticity be significantly improved, apparent downward trend is presented in wrinkle of skin score value；Comprehensive each embodiment eye mask patch
The effect of formulation cost and effect achieved, the cost performance highest of embodiment 3.
Test the test of 6 Vitamin Ks
Test method: choosing 5 eyes has black-eyed volunteer, black using the crease-resistant of above-described embodiment 1-5 and desalination respectively
Eyelet eye mask patch persistently uses 21 days daily using once, and uses the 0th lasting to this 5 experimenters respectively with chromascope
It, the 7th day, the 14th day, the 21st day eye black eye coloration was tested.Test result is as follows table 6.
6 Vitamin K of table evaluates data
Asian skin colours' coloration is close to 6 under normal circumstances, and the coloration of test in the 21st day shows the present invention all close to 6 in upper table 6
The crease-resistant and Vitamin K eye mask patch that each embodiment is prepared, has the function of Vitamin K.
It can be seen that crease-resistant and Vitamin K eye mask patch of the invention has desalination microgroove, reduces wrinkle, improves skin
Elasticity, delays the effect of eye aging at Vitamin K.
The above described is only a preferred embodiment of the present invention, limitation in any form not is done to the present invention, therefore
All contents without departing from technical solution of the present invention, it is made to the above embodiment according to the technical essence of the invention any simply to repair
Change, equivalent variations and modification, all of which are still within the scope of the technical scheme of the invention.
Claims (10)
1. a kind of eye mask patch, which is characterized in that mainly contain the component of following weight percentage:
Horse chestnut extract 0.2~1%,
Glucityl aurantiamarin 0.1~1%,
Peony root extractive 0.5~3%.
2. eye mask patch according to claim 1, which is characterized in that the eye mask patch also contains following weight percentage
Component:
1 ‰ -5 aqueous solution 1~5% of palmityl tripeptides,
Carnosine 0.1~0.5%,
Micromolecule hyaluronic acid sodium 0.1~0.3%.
3. eye mask patch according to claim 1 or 2, which is characterized in that also contain the component of following weight percentage:
Moisturizer 4.5-13%,
Preservative 0.2-0.5%,
Rheology modifiers 0.15-0.45%.
4. eye mask patch according to claim 3, which is characterized in that the moisturizer is by 1,3-PD, glycerol, beet
Alkali composition, the 1,3-PD, glycerol, glycine betaine mass ratio be (2-5): (2-5): (1-3).
5. eye mask patch according to claim 3, which is characterized in that the preservative is silver ion antimicrobial agent, described
The additive amount of silver ion antimicrobial agent is 0.3-0.4wt%.
6. eye mask patch according to claim 3, which is characterized in that the rheology modifiers are carbomer.
7. eye mask patch according to claim 1 or 2, which is characterized in that the eye mask patch is additionally added dipotassium glycyrrhizinate, institute
The additive amount for the dipotassium glycyrrhizinate stated is 0.1~0.5wt%.
8. the preparation method of any one of the claim 1-7 eye mask patch, which comprises the following steps:
(1) 1,3- propylene glycol, glycerol, carbomer, micromolecule hyaluronic acid sodium and purified water are mixed and is added in the ratio
Heat is to 85~90 DEG C, and homogeneous 10 minutes, insulated and stirred started to cool down after 30 minutes；
(2) when being cooled to 45 DEG C, sequentially add glycine betaine, horse chestnut extract, glucityl aurantiamarin, dipotassium glycyrrhizinate, carnosine,
Palmityl tripeptides -5 and peony root extractive, stir evenly；
(3) silver ion preservative is added after above-mentioned raw materials are completely dispersed uniformly, stirring to room temperature discharges after detection is qualified.
9. eye mask patch according to claim 8, which is characterized in that the preparation method of the eye mask patch further includes step
(4): eye mask patch Essence being poured into the packaging material containing film cloth, sealing obtains a kind of eye mask patch.
10. eye mask patch according to claim 9, which is characterized in that the material of the film cloth is non-woven fabrics, biological fiber
Material, pectin fiber cloth, any one in silk fiber cloth.
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| CN201910281904.9A CN110037952A (en) | 2019-04-09 | 2019-04-09 | A kind of crease-resistant and Vitamin K eye mask patch |
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| CN201910281904.9A CN110037952A (en) | 2019-04-09 | 2019-04-09 | A kind of crease-resistant and Vitamin K eye mask patch |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110585030A (en) * | 2019-09-27 | 2019-12-20 | 广州香枝化妆品有限公司 | High-molecular gel wrinkle-removing eye mask and preparation method thereof |
| CN110721102A (en) * | 2019-10-29 | 2020-01-24 | 佛山科学技术学院 | Eye mask with moisturizing, anti-wrinkle and anti-oxidation effects |
| CN111728936A (en) * | 2020-08-20 | 2020-10-02 | 博雅(广州)生物科技研究院有限公司 | Eye repair essence and preparation method thereof |
| CN111939086A (en) * | 2020-08-24 | 2020-11-17 | 博雅(广州)生物科技研究院有限公司 | Eye mask with moisturizing and blackening functions and preparation method thereof |
| CN111973506A (en) * | 2020-07-23 | 2020-11-24 | 广州市科能化妆品科研有限公司 | Composition for resisting wrinkles, removing dark circles and removing pouches and application thereof |
| CN113813205A (en) * | 2021-09-10 | 2021-12-21 | 仙婷(广州)科技研发有限公司 | Multifunctional eye care composition and application thereof |
| CN113876661A (en) * | 2021-11-04 | 2022-01-04 | 天津郁美净集团有限公司 | Anti-aging composition for eyes and application thereof |
| CN114177279A (en) * | 2021-12-23 | 2022-03-15 | 广西信业生物技术有限公司 | Medical eye patch with nano microcapsule structure and preparation method thereof |
| CN115006322A (en) * | 2022-06-06 | 2022-09-06 | 广东丸美生物技术股份有限公司 | Formula of instant and long-acting multifunctional eye mask and preparation method thereof |
| CN115501163A (en) * | 2021-06-07 | 2022-12-23 | 广州悦荟化妆品有限公司 | Forehead patch with effects of removing wrinkles and tendering skin |
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| CN115501163A (en) * | 2021-06-07 | 2022-12-23 | 广州悦荟化妆品有限公司 | Forehead patch with effects of removing wrinkles and tendering skin |
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| CN115006322A (en) * | 2022-06-06 | 2022-09-06 | 广东丸美生物技术股份有限公司 | Formula of instant and long-acting multifunctional eye mask and preparation method thereof |
| CN115006322B (en) * | 2022-06-06 | 2023-09-19 | 广东丸美生物技术股份有限公司 | Formula and preparation method of multifunctional eye mask with instant and long-acting effects |
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