CN109965272A - A kind of children's lead discharging tailored version clinical nutrition formula and preparation method thereof - Google Patents

A kind of children's lead discharging tailored version clinical nutrition formula and preparation method thereof Download PDF

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Publication number
CN109965272A
CN109965272A CN201910267971.5A CN201910267971A CN109965272A CN 109965272 A CN109965272 A CN 109965272A CN 201910267971 A CN201910267971 A CN 201910267971A CN 109965272 A CN109965272 A CN 109965272A
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parts
powder
vitamin
children
lead
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尤俊
季敬东
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Shanghai Olympic Medical Biotechnology Co Ltd
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Shanghai Olympic Medical Biotechnology Co Ltd
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L13/00—Meat products; Meat meal; Preparation or treatment thereof
    • A23L13/20—Meat products; Meat meal; Preparation or treatment thereof from offal, e.g. rinds, skins, marrow, tripes, feet, ears or snouts
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L13/00—Meat products; Meat meal; Preparation or treatment thereof
    • A23L13/30—Meat extracts
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L17/00—Food-from-the-sea products; Fish products; Fish meal; Fish-egg substitutes; Preparation or treatment thereof
    • A23L17/40—Shell-fish
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L17/00—Food-from-the-sea products; Fish products; Fish meal; Fish-egg substitutes; Preparation or treatment thereof
    • A23L17/60—Edible seaweed
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
    • A23L19/10—Products from fruits or vegetables; Preparation or treatment thereof of tuberous or like starch containing root crops
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L31/00—Edible extracts or preparations of fungi; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/185—Vegetable proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Abstract

The present invention relates to a kind of children's lead discharging tailored version clinical nutrition formulas comprising: 25-30 parts of protein, 0.2-2 parts of fat, 48-55 parts of carbohydrate, 8-12 parts of dietary fibers, 0.3-0.8 parts of macroelements, 0.1-0.25 parts of microelements, 0.01-0.05 parts of liposoluble vitamins, 0.15-0.3 parts of water soluble vitamins, 0.4-5 parts of diet essence, 0.3-2.5 parts of integration of drinking and medicinal herbs ingredients and 0.2-0.5 parts of new resource foods；The invention further relates to the preparation methods of above-mentioned clinical nutrition formula.The present invention is based on the intracorporal lead accumulations of children, add the specific nutrients such as integration of drinking and medicinal herbs ingredient, diet essence and the new resource food with radiation protection lead discharging, resistance building and other effects, and it adjusts its proportion and carries out compatibility synergy with basal nutrient element, the supplement daily required nutritional ingredient of children comprehensively, and the nutrient formulation is easier to be absorbed by digestant for baby, the effect of giving full play to its each component, effectively prevent the lead poisoning of children, and promote the discharge of excessive lead in vivo, guarantee growing up healthy and sound in all respects for children.

Description

A kind of children's lead discharging tailored version clinical nutrition formula and preparation method thereof
Technical field
The present invention relates to special medicine purposes formula food fields, and in particular to a kind of children's lead discharging tailored version clinical nutrition Formula and preparation method thereof.
Background technique
Radioactive substance is widely used in science and technology, production and daily life, inevitably gives people's lives environment And human body causes radioactive pollution and radiation to cause harm, wherein being also people institute growing interest for the seriousness that human body is caused harm.So far Until the present, when malignant tumor patient clinical treatment, about 70% or more cancer patient be unable to do without radiotherapy, if only by The harm for avoiding contact with or eliminating by physical protection radiation has obviously been not enough to carry out effective protection.Give exogenous material To body recovery immune function is helped, mitigating radiation injury has positive effect.
Lead is a kind of polyaffinity poisonous substance, into body after have an adverse effect to body multisystem, and subclinical Level has made body generate a variety of physiological changes, and main is the intellectual development and growth and development for influencing child.90% lead exists Skeletal system, it is other to be present in blood.Lead Toxicity is lasting, and long half time was not easy to be discharged by human body up to 10 years, because of this person The content of internal lead is 5 times in environment, and lower limit is not present in lead contamination, and the lead contamination of any degree has can be strong to human body Health has an adverse effect.And even if being detached from Lead pollution environment, carry out driving lead treatment, Pb-B decline, but can not make Original normal level is restored to through impaired neural cell development.
U.S. CDC (national Center for Disease Control) nineteen eighty-two " children's lead poisoning guide " regulation " Pb-B be more than or Equal to 100 μ g/L, regardless of whether having corresponding clinical symptoms, Signs and the variation of other blood biochemicals that can be diagnosed as " children's lead Poisoning ", and the Pb-B of children is divided into Pyatyi, to indicate different lead load states.It endangers in view of lead poisoning to children It is harmful without threshold value, developed country and the Chinese government propose to carry out " zero splicer's journey " that (i.e. internal lead tolerance is " zero's " in recent years Desirable level).Currently, the metropolitan medical child health care mechanism of Systems in Certain Developed Countries and China is by the diagnosis of children's lead poisoning Standard is determined as 50 μ g/L.
Occur all kinds of common lead discharging drugs currently on the market, although lead-eliminating effect preferably, is generally both needed to for a long time Intravenous injection, and other microelements can be discharged simultaneously, the reduction of relevant enzyme physiological activity is caused, Emergency use is suitable only for.Cause This, it is very necessary for developing a kind of nutrient that can be taken for a long time comprehensively and facilitating the infant nutrition formula of lead discharging.
Summary of the invention
The purpose of the present invention is to overcome the defects in the prior art, provides a kind of for children's lead discharging tailored version clinic battalion Formula is supported, the daily nutrition demand of children can be met, and help to excrete heavy metal lead, enhances children's resistance, To guarantee the normal growth of children.
To achieve the above object, the present invention adopts the following technical scheme:
The first purpose of the invention is to provide a kind of children's lead discharging tailored version clinical nutrition formulas comprising following component And its parts by weight: 25-30 parts of protein, 0.2-2 parts of fat, 48-55 parts of carbohydrate, 8-12 parts of dietary fibers, 0.3- 0.8 part of macroelement, 0.1-0.25 parts of microelements, 0.01-0.05 parts of liposoluble vitamins, 0.15-0.3 parts of water soluble vitamins are raw Element, 0.4-5 parts of diet essence, 0.3-2.5 parts of integration of drinking and medicinal herbs ingredients and 0.2-0.5 parts of new resource foods.
In order to advanced optimize above-mentioned clinical nutrition formula, technical measures adopted by the present invention further include:
Further, the protein is selected from concentrated whey protein powder, soybean protein isolate, Isin glue collagen peptide, full-cream At least one of milk powder, dried whole-egg, lactoferrin, bovine colostrum, amino acid, protein peptides.
Wherein, the amino acid is selected from L-lysine-Pidolidone, Pidolidone, L-arginine, L-Trp, L- paddy At least one of glutamine, taurine, Valine, l-Isoleucine, L-Leu；The protein peptides are selected from hydrolyzed whey Albumen, soybean oligopeptide, wheat protein peptide, pupa albumen peptide, ocean fish oligopeptide powder, laughable peptide, amino peptide, ovalbumin peptide At least one of.
Further, the protein includes concentrated whey protein powder, soybean protein isolate, bovine colostrum and ox sulphur Acid.
Further, the fat includes saturated fatty acid, polyunsaturated fatty acid, monounsaturated fatty acids, OPO knot At least one of structure rouge, DHA, EPA, ARA, phosphatide, the more specifically described fat includes safflower seed oil, walnut oil, peanut Oil, soybean oil, Ah's glycerol, olive oil, tea oil, oil and fat of sacha inchi, olive oil, coconut oil, cupu oil, palm oil, butter, cream, Lard, medium chain triglyceride, lecithin, Purple Perilla Seed Oil, DHA algal oil, arachidonic acid oil, phosphatide etc.；More preferably purple perilla Seed oil, the form which is prepared into Purple Perilla Seed Oil microcapsule powder are added.
Further, the carbohydrate includes fructose, rock sugar, lactose, maltodextrin, tapioca, resistant starch At least one of；More preferably maltodextrin.
Further, the dietary fiber includes inulin, konjaku flour, galactooligosaccharide, oligofructose, oligomeric different malt At least one of sugar, soybean polyoses, cyclodextrin, resistant dextrin, soybean fiber；It is highly preferred that the dietary fiber includes low Fructooligosaccharides and resistant dextrin.
Further, the macroelement is selected from calcium citrate, L-calcium lactate, calcium monohydrogen phosphate, K-IAO, citric acid At least one of sodium and magnesium gluconate；More preferably: calcium, wherein calcium is with calcium citrate, L- calcium lactate, calcium monohydrogen phosphate Any one or several form additions.
Further, the microelement is selected from ferrous gluconate, zinc gluconate, potassium iodide, copper gluconate, sulphur At least one of sour manganese, more preferably: iron and zinc, wherein iron is added in the form of ferrous gluconate, and zinc is with gluconic acid The form of zinc is added.
Further, the liposoluble vitamin is selected from vitamin A, beta carotene, vitamin D3, vitamin E, dimension life Plain K1At least one of；More preferably: vitamin A, beta carotene, vitamin D3, vitamin E.
Further, the water soluble vitamin is selected from vitamin B1, vitamin B2, vitamin B6, vitamin B12, dimension life At least one of plain C, pantothenic acid, folic acid, niacin, choline, inositol, biotin；More preferably: vitamin B1, vitamin B2, dimension Raw element B6, vitamin B12, vitamin C, niacin, folic acid, pantothenic acid.
Further, the diet essence be selected from oatmeal, buckwheat, red bean powder, garlic powder, carrot meal, Kelp Powder, At least one of tremella powder, pork liver powder；More preferably: garlic powder, carrot meal, Kelp Powder, tremella powder, pork liver powder.
Further, the integration of drinking and medicinal herbs ingredient is selected from Radix Glycyrrhizae, lophatherum gracile powder, lotus seeds, honeysuckle, hawthorn, orange peel, black sesame One of fiber crops, cordate houttuynia, fructus lycii, endothelium corneum gigeriae galli more preferably include Semen sesami nigrum, cordate houttuynia, fructus lycii, endothelium corneum gigeriae galli.
Further, it is few to be selected from first milk basic protein, hydrolysis yolk powder, γ-aminobutyric acid, shell for the new resource food Sugar, eucommia Bark male flower, bamboo-leaves flavones, casein phosphopeptide, fish oil, avenabeta glucosan, Oligomeric manna sugar, Rosa roxburghii Tratt, yeast β-Portugal At least one of glycan, newborn mineral salt, pueraria root powder, Rosa roxburghii Tratt, xylo-oligosaccharide；More preferably Oligomeric manna sugar.
Further, in above-mentioned clinical nutrition formula, the protein includes concentrated whey protein powder, soybean separation protein White, bovine colostrum and amino acid；The fat includes Purple Perilla Seed Oil；The carbohydrate includes maltodextrin；The diet Fiber includes oligofructose and resistant dextrin；The diet essence includes garlic powder, carrot meal, Kelp Powder, tremella powder, pork liver Powder；The integration of drinking and medicinal herbs ingredient includes Semen sesami nigrum, cordate houttuynia, fructus lycii, endothelium corneum gigeriae galli；The macroelement includes calcium；It is described micro Element includes iron and zinc；The liposoluble vitamin includes vitamin A, beta carotene, vitamin D3, vitamin E；The water Soluble vitamin includes vitamin B1, vitamin B2, vitamin B6, vitamin B12, vitamin C, niacin, folic acid, pantothenic acid；It is described New resource food includes Oligomeric manna sugar.
Further, the integration of drinking and medicinal herbs ingredient includes: 0.1-0.5 portions of Semen sesami nigrums, 0.1-0.5 parts of cordate houttuynias, 0.1- 0.5 portion of fructus lycii, 0.1-0.5 parts of endothelium corneum gigeriae gallis.
Further, the amino acid includes 0.12 part of taurine.
Further, the nutrient formulation further includes metallothionein, shrimp powder, black fungus powder and alginic acid, weight Number is 0.2~0.8 part.
Further, the clinical nutrition formula include: 50 portions of maltodextrins, 20 parts of concentrated whey protein powders, 6 parts it is low Fructooligosaccharides, 6 parts of soybean protein isolates, 4 parts of resistant dextrins, 0.2-2 parts of Purple Perilla Seed Oil microcapsule powders, 0.6 part of bovine colostrum, 0.1-1 Part garlic powder, 0.1-1 parts of carrot meals, 0.1-1 parts of Kelp Powders, 0.1-1 parts of tremella powder, 0.1-0.5 parts of pork liver powders, 0.1-0.5 Part Semen sesami nigrum, 0.1-0.5 portions of cordate houttuynias, 0.1-0.5 portions of fructus lyciis, 0.1-0.5 parts of endothelium corneum gigeriae gallis, 0.4 part of Oligomeric manna sugar, 0.42 Part calcium, 0.018 part of iron, 0.016 part of zinc, 0.002 part of vitamin A, 0.005 part of beta carotene, 0.000002 part of vitamin D3, 0.016 part of vitamin E, 0.002 part of vitamin B1, 0.002 part of vitamin B2, 0.002 part of vitamin B6, 0.000004 part Vitamin B12, 0.2 part of vitamin C, 0.02 part of niacin, 0.0004 part of folic acid, 0.006 part of pantothenic acid, 0.12 part of taurine.
A second object of the present invention is to provide a kind of preparation methods of above-mentioned children's lead discharging tailored version clinical nutrition formula Method comprising following steps:
Step 1) prepares fat powder, liposoluble vitamin powder and water soluble vitamin powder using micro-capsule embedding techniques End；
Step 2) mentioned using crushing, alcohol extracting, water, be spray-dried and sifting step prepares integration of drinking and medicinal herbs component powders；
Step 3) is smart by the protein of predetermined weight, carbohydrate, dietary fiber, macroelement, microelement, diet China and new resource food are prepared into the powder that partial size is 150~250 μm respectively, if necessary can be preparatory by above-mentioned raw materials It carries out baking processing；
Step 4) is by step 1)~3) powder of preparation sterilize after mixing it is spare；
The mixed powder of step 4) is prepared into nutrient powder, nutrition emulsion, capsule according to conventional technical means by step 5) At least one of agent, tablet, pill or oral solution；
Wherein, step 1) -3) sequence can mutually replace.
Finally, the present invention relates to a kind of products prepared by above-mentioned children's brain growth tailored version clinical nutrition formula, including Nutrient powder, nutrition emulsion, capsule, tablet, pill, oral solution etc..
In the above preparation method, wherein the raw material of the integration of drinking and medicinal herbs ingredient crushed, alcohol extracting concentration, water concentrate Contracting, and concentrate is subjected to spray drying, integration of drinking and medicinal herbs component powders are made；Wherein, the vitamin and fat are respectively by micro- Encapsulated processing is prepared into vitamin powder and fat powder.
Preferably, the preparation process of the integration of drinking and medicinal herbs component powders is as follows: using pulverizer to predetermined weight number Raw material is crushed, and the raw material of crushing is placed in container, and 7~8 times of 30~40% second that weight is raw material weight are added Alcohol is impregnated, is extracted 3 times, is merged alcohol extract and is concentrated into no alcohol taste；After the raw medicine dregs of a decoction fling to ethyl alcohol, it is original that weight, which is added, 3~4 times of water of material weight is impregnated, and carries out 15~20min of decoction to soak, filtering removal raw material leaves and takes decoction Liquid；Alcohol extract and decoction liquor after merging concentration, and it is spray-dried, it is same finally to prepare medicine food with 60~80 meshes point Derived components powder.
Preferably, specific step is as follows for the microencapsulation processing of the vitamin: 1) using liposoluble vitamin as core Material selects sodium carboxymethylcellulose, gelatin, carragheen, xanthan gum, Arabic gum, maltodextrin, lipoprotein, corn syrup, big Beans protein isolate, whole-fat milk powder, dietary fiber, inulin, PURE WHEY, oligoisomaltose, soybean fiber, lactose, rock sugar One of powder, emulsifier, stabilizer are a variety of as wall material, and high-pressure homogeneous emulsification is spraying instantaneous dry, with 60~80 meshes Divide and prepares liposoluble vitamin powder；2) using water soluble vitamin as core material, sodium carboxymethylcellulose, gelatin, OK a karaoke club are selected Glue, xanthan gum, Arabic gum, maltodextrin, lipoprotein, corn syrup, soybean protein isolate, whole-fat milk powder, dietary fiber, chrysanthemum One of powder, PURE WHEY, oligoisomaltose, soybean fiber, lactose, candy sugar powder, emulsifier, stabilizer or a variety of works For wall material, it is uniformly mixed, it is spraying instantaneous dry, water soluble vitamin powder is prepared with 60~80 meshes point.
Preferably, the specific implementation step of the micro-capsule embedding techniques of the fat is as follows: by fat, emulsifier, wall material with Water mixed dissolution prepares emulsion；After above-mentioned emulsion is stirred, emulsifying homogeneous processing is carried out, is then done by spraying Dry, screening prepares fat powder, and fat powder is compared with conventional grease, and dispersibility, water solubility, emulsibility, inoxidizability are all It improves a lot；Wherein, the emulsifier be selected from fatty acid glyceride (glyceride), methyl glycol fatty acid ester (propylene glycol ester), Sorbitan aliphatic ester (sorbitan acid), sucrose fatty ester (sucrose ester), lecithin, monoglyceride, one in Tween 80 Kind is a variety of；The wall material is selected from sodium carboxymethylcellulose, gelatin, carragheen, xanthan gum, Arabic gum, maltodextrin, rouge egg White, corn syrup, soybean protein isolate, whole-fat milk powder, dietary fiber, inulin, PURE WHEY, oligoisomaltose, soybean One of fiber, lactose, candy sugar powder, emulsifier, stabilizer are a variety of.
The present invention also provides a kind of preparation methods of above-mentioned children's lead discharging tailored version clinical nutrition formula, are wet process work Skill includes the following steps:
Step 1) prepare the protein containing predetermined weight number, fat, carbohydrate, dietary fiber, macroelement, Microelement, vitamin, diet essence, integration of drinking and medicinal herbs ingredient and new resource food raw material pressed in the water of predetermined amount It according to the physical behavior of raw material, successively adds according to sequencing, is stirred while addition, the mixing cream of raw material is made Liquid；
The mixed emulsion temperature that step 1) obtains is maintained at 40-50 DEG C by step 2), and adjustment homogenization pressure protects it always It holds between 10-18Mpa, emulsifying homogeneous is carried out to mixed emulsion, is then placed emulsion in evaporator, with preset technology Parameter is concentrated, and is sterilized at 85-88 DEG C, and concentrate is obtained；
The concentrate that step 2) obtains is spray-dried by step 3), is crossed 60~80 meshes, is prepared into powder；Using upper It states powder and is prepared at least one of nutrient powder, nutrition emulsion, capsule, tablet, pill or oral solution.
Compared with prior art, the invention has the following advantages:
In the present invention using including Semen sesami nigrum, cordate houttuynia, fructus lycii, endothelium corneum gigeriae galli integration of drinking and medicinal herbs ingredient；Wherein, Semen sesami nigrum, Have effects that nourishing liver and kidney, moisturizing viscera, benefiting energy, long muscle, fill out brains, theory of traditional Chinese medical science thinks that black enters kidney, " Shen controls bone liter Marrow passes through brain ", various radiation hazradial bundles mainly influence human brain and marrow, compromised immune is made one, and edible Semen sesami nigrum can Enhance Cellular Immunity and humoral immune function, it can effective protection human health；Cordate houttuynia total flavones in cordate houttuynia are to spoke Penetrating damage mouse has good protective action, and mouse alcohol extracting general flavone is given in stomach-filling to Bao Jun et al. by oral administration, using 60Co- γ Radiographic source is disposably irradiated, measurement peripheral white blood cells, lymphocyte number and weight, to cordate houttuynia total flavones Radiation protection is verified；It is living that fructus lycii can increase peripheral white blood cell, reduction micronuclear rates, raising proliferation of bone marrow cells Property, have the function of Antiradiation injury, in thunder et al. by carrying out the stomach-filling of fructus lycii solution to kunming mice, then carries out accumulated dose and be The activity of the full-body exposure of 2.0Gy, detection peripheral blood white blood cell count, Bone Marrow Micronuclear Rates and proliferation of bone marrow cells prevents fructus lycii Radiation effects is verified；Endothelium corneum gigeriae galli, it is sweet in flavor mild-natured, have stomach invigorating and digestion promoting effects, dissolving and expelling accumulated stones, relieving dyspepsia, width in invigorating the spleen, invigorating the spleen The effect of stomach function regulating, can promote the digestion and absorption of each nutriment.
The present invention use including garlic powder, carrot meal, Kelp Powder, tremella powder, pork liver powder diet essence；Wherein, greatly The garlic oil contained in garlic powder has radiation resistance, and Wang Hongxin et al. passes through the experiment side with garlic oil soft capsule feeding mouse Method, influence of the observation gamma Rays front and back to Micronucleus, peripheral white blood cell, bone marrow cell DNA, is tested The radiation resistance of garlic oil is demonstrate,proved；Carrot meal contains a large amount of pectin, can reduce the toxicity of lead in vivo, reduces the suction of lead It receives；Laminarin in Kelp Powder can remove intracorporal lipid peroxide, reduce and prevent active oxygen, free radical to tissue Damage, at the same in experimental study, it has been found that the activity that LJP has anti-apoptotic, protects immune function, to radiation-induced rat Salivary gland apoptosis is inhibited, has the radiation proof effect of absurd fantastic gland；Tremella polysaccharides contained by tremella powder have it is anti-radiation, Anti-oxidant, strengthen immunity, increase leucocyte, it is hypoglycemic and antitumor the effects of, can treat hypertension, hyperlipidemia, diabetes, The various diseases such as hepatitis B；Vitamin A rich in pork liver can protect eyes, maintain twenty-twenty vision, and pork liver also contains Abundant vitamin B2, this completes body and plays an important role to the detoxification of some toxic components, also to the important coenzyme of body is supplemented Containing vitamin C and trace elements of selenium, the immune response of human body can be enhanced, promote the discharge of heavy metal.
The present invention also adds beta carotene, quenching singlet oxygen and can capture free radical, is a kind of very effective Lipid antioxidant, make oxygen radical chemical activity lose, mitigate the damaging action of free radical.Meanwhile beta carotene is again VA can be converted into and play " anti-infective ".VE is also one of most important Biological Free Radicals scavenger in organism, it can lead to It crosses reduction and interrupts unsaturated fat acid oxidase, formation+free radical can be combined well with oxygen radical, reduces the damage of DNA, Referred to as antidote and antimutanen.Therefore, beta carotene and VE are played important as second defense system in vivo Anti-oxidation function, to radiation injury have important defense reaction.Vitamin C inhibits human body to play very your writing to the absorption of lead With.
The soybean protein that the present invention adds essential amino acid glutamine rich in and various essential nutrients, With radiation resistance；And by the study found that soybean protein effectively reduce radiation to the damage of intestinal mucosa, promote damaging mucosal It repairs and radiation insult intestinal mucosa regenerates, can treat radiation-induced radiation enteritis.
The present invention also provides metallothionein, shrimp powder, black fungus powder and alginic acids；Wherein, metallothionein is a kind of Small protein rich in cysteine plays the role of preventing from heavy metal toxicity in the cell, contained by sulfydryl can be with Lead forms low toxicity or nontoxic chelate, and stable structure can be excreted by metabolism, avoid the accumulation of lead in vivo；Shrimp Calcium rich in skin, facilitates the excretion of lead；Black fungus has good anticancer function, and has the function for removing lead poisoning Can, it is often edible, it can effectively remove intracorporal lead poisoning and other harmful substances；Alginic acid is polysaccharide macromolecular substance, Free-OH and-COOH group abundant can be complexed with lead on sugar chain, and formation is difficult to the gel absorbed, and effectively prevention lead is in stomach The absorption of enteron aisle is played the role of promoting lead discharging.
The present invention is by selecting reasonable basal nutrient element, based on the intracorporal lead accumulation of children, to the proportion of each component into Row be adaptively adjusted, while add have radiation protection lead discharging, resistance building and other effects integration of drinking and medicinal herbs ingredient, diet essence and The specific nutrients such as new resource food, and adjust its proportion and carry out compatibility synergy with basal nutrient element, it is daily that children are supplemented comprehensively Required nutritional ingredient, and the nutrient formulation is easier the effect of being absorbed by digestant for baby, giving full play to its each component, effectively Prevent the lead poisoning of children, and promote the discharge of excessive lead in vivo, guarantees growing up healthy and sound in all respects for children.
Specific embodiment
The present invention provides a kind of children's lead discharging tailored version clinical nutrition formula, including following component and its parts by weight: 25- 30 parts of protein, 0.2-2 parts of fat, 48-55 parts of carbohydrate, 8-12 parts of dietary fibers, 0.3-0.8 parts of macroelements, 0.1-0.25 parts of microelements, 0.01-0.05 parts of liposoluble vitamins, 0.15-0.3 parts of water soluble vitamins, 0.4-5 portions of diets Essence, 0.3-2.5 parts of integration of drinking and medicinal herbs ingredients and 0.2-0.5 parts of new resource foods.
With reference to embodiment, the specific embodiment of the present invention is further described.Following embodiment is only used for more Add and clearly demonstrate technical solution of the present invention, and not intended to limit the protection scope of the present invention.
Embodiment 1
Children's lead discharging tailored version clinical nutrition formula of the present invention includes maltodextrin 50g, concentrated whey protein powder 20g, oligofructose 6g, soybean protein isolate 6g, resistant dextrin 4g, Purple Perilla Seed Oil microcapsule powder 2g, bovine colostrum 0.6g, garlic powder 1g, carrot meal 1g, Kelp Powder 1g, tremella powder 1g, pork liver powder 0.5g, Semen sesami nigrum 0.5g, cordate houttuynia 0.5g, fructus lycii 0.5g, chicken Interior gold 0.5g, Oligomeric manna sugar 0.4g, calcium 0.42g, iron 0.018g, zinc 0.16g, vitamin A 0.002g, beta carotene 0.005g, vitamin D30.000002g, vitamin E 0.016g, vitamin B10.002g, vitamin B20.002g, vitamin B60.002g, vitamin B120.000004g, vitamin C 0.2g, niacin 0.02g, folic acid 0.0004g, pantothenic acid 0.006g, ox Sulfonic acid 0.12g.
Embodiment 2
Children's lead discharging tailored version clinical nutrition formula of the present invention includes maltodextrin 50g, concentrated whey protein powder 20g, oligofructose 6g, soybean protein isolate 6g, resistant dextrin 4g, Purple Perilla Seed Oil microcapsule powder 2g, bovine colostrum 0.6g, garlic powder 0.1g, carrot meal 0.1g, Kelp Powder 0.1g, tremella powder 0.1g, pork liver powder 0.1g, Semen sesami nigrum 0.1g, cordate houttuynia 0.1g, Chinese holly Qi 0.1g, endothelium corneum gigeriae galli 0.1g, Oligomeric manna sugar 0.4g, calcium 0.42g, iron 0.018g, zinc 0.16g, vitamin A 0.002g, β- Carrotene 0.005g, vitamin D30.000002g, vitamin E 0.016g, vitamin B10.002g, vitamin B2 0.002g, vitamin B60.002g, vitamin B120.000004g, vitamin C 0.2g, niacin 0.02g, folic acid 0.0004g, Pantothenic acid 0.006g, taurine 0.12g.
Embodiment 3
Children's lead discharging tailored version clinical nutrition formula of the present invention includes maltodextrin 50g, concentrated whey protein powder 20g, oligofructose 6g, soybean protein isolate 6g, resistant dextrin 4g, Purple Perilla Seed Oil microcapsule powder 0.2g, bovine colostrum 0.6g, garlic Powder 0.1g, carrot meal 0.1g, Kelp Powder 0.1g, tremella powder 0.1g, pork liver powder 0.1g, Semen sesami nigrum 0.1g, cordate houttuynia 0.1g, Fructus lycii 0.1g, endothelium corneum gigeriae galli 0.1g, Oligomeric manna sugar 0.4g, calcium 0.42g, iron 0.018g, zinc 0.16g, vitamin A 0.002g, Beta carotene 0.005g, vitamin D30.000002g, vitamin E 0.016g, vitamin B10.002g, vitamin B2 0.002g, vitamin B60.002g, vitamin B120.000004g, vitamin C 0.2g, niacin 0.02g, folic acid 0.0004g, Pantothenic acid 0.006g, taurine 0.12g.
Embodiment 4
Children's lead discharging tailored version clinical nutrition formula of the present invention includes maltodextrin 50g, whey protein concentrate Powder 20g, oligofructose 6g, soybean protein isolate 6g, resistant dextrin 4g, Purple Perilla Seed Oil microcapsule powder 2g, bovine colostrum 0.6g, garlic Powder 1g, carrot meal 1g, Kelp Powder 1g, tremella powder 1g, pork liver powder 0.5g, black sesame powder 0.5g, cordate houttuynia 0.5g, fructus lycii 0.5g, endothelium corneum gigeriae galli 0.5g, Oligomeric manna sugar 0.4g, calcium 0.42g, iron 0.018g, zinc 0.16g, vitamin A 0.002g, β-Hu Luo Bu Su 0.005g, vitamin D30.000002g, vitamin E 0.016g, vitamin B10.002g, vitamin B20.002g, dimension Raw element B60.002g, vitamin B120.000004g, vitamin C 0.2g, niacin 0.02g, folic acid 0.0004g, pantothenic acid 0.006g, taurine 0.12g, metallothionein 0.2g, shrimp powder 0.3g, black fungus powder 0.5g and alginic acid 0.4g.
Embodiment 5
A kind of children's lead discharging tailored version clinical nutrition formula as described in Example 1 the preparation method is as follows:
1) powdered oil (powder fat) is prepared:
A) it prepares wall material aqueous solution: taking 8 grams of maltodextrin, 4 grams of soybean protein isolate, 11 grams of whole-fat milk powder, dietary fiber 2 Gram (resistant dextrin), 0.5 gram of inulin, 5 grams of PURE WHEY, 0.2 gram of Arabic gum, 2 grams of candy sugar powder, 50 milliliters of water stir evenly (have ready conditions and heat while stirring to 60 DEG C, be cooled to room temperature after being kept for 30 minutes).
B) 0.1 gram (total solid concentration is 0.2%) is taken uniformly to be dissolved in (Purple Perilla Seed Oil in 25 milliliters of greases monoglyceride 25ml)。
C) 0.1 gram (total solid concentration is 0.2%) is taken uniformly to be dissolved in wall material aqueous solution Tween 80.
D) the wall material aqueous solution of the mixed plant grease and addition Over emulsfication agent Tween 80 of Over emulsfication agent monoglyceride will be added It is sufficiently mixed.
E) addition stabilizer agar takes 0.1 gram (total solid concentration be 0.2%) into after mixed solution, is settled to water 200 milliliters (total solid concentration be 25%), high speed dispersion 2 minutes under 20000r/min.
F) homogenization pressure is 25MPa, and homogeneous 3 times (every time 5 minutes), homogeneous emulsion is made.
G) emulsion obtained is spray-dried, inlet air temperature is 195 DEG C, and leaving air temp is 80 DEG C.
Collect powdered oil (powder fat)；
2) integration of drinking and medicinal herbs component powders are prepared: being crushed, will be crushed using raw material of the pulverizer to predetermined weight number Raw material be placed in container, crushed using raw material of the pulverizer to predetermined weight number, the raw material of crushing be placed in container In, be added weight be raw material weight 3~8 times of water, carry out immersion 3~4 hours, then to soak carry out decoction 30~ 60min, filtering removal raw material, leaves and takes decoction liquor, is spray-dried to decoction liquor, prepares integration of drinking and medicinal herbs with 60~80 meshes point Component powders；
3) prepare vitamin powder: using the liposoluble vitamin of predetermined weight number as core material, select carragheen, I Primary glue carries out 2 emulsifying homogeneous processing as wall material under high pressure, and the emulsifying homogeneous time is 10~15min, is then sprayed Mist is instantaneously dried, and prepares liposoluble vitamin powder with 60~80 meshes point；The water soluble vitamin of predetermined weight number is made For core material, selects maltodextrin, lipoprotein as wall material, be uniformly mixed, it is spraying instantaneous dry, water is prepared with 60~80 meshes point Soluble vitamin powder；
4) by the protein of predetermined weight, carbohydrate, dietary fiber, macroelement, microelement, diet essence with And new resource food is prepared into the powder that partial size is 150~250 μm respectively；(step 1) -4) sequence can mutually replace)
5) by step 1) -4) powder of preparation sequentially adds the mixing machines of cone-type mixer or other forms and is uniformly mixed system Formula mixture is obtained, it is spare after sterilization processing；
6) according to conventional technical means by the formula mixture in step 5) be prepared into nutrient powder, nutrition emulsion, capsule, At least one of tablet, pill or oral solution.
In step 6), optionally increase suitable food thickening agent, food additives and related dosage form auxiliary material. The food thickening agent is guar gum, in xanthan gum, locust bean gum, konjac glucomannan, pectin, carragheen, agar, gelatin, Arabic gum At least one, the food additives be at least one of xylitol, edible essence fragrance, brown sugar；More preferable carragheen, Arabic gum, guar gum, Aspartame, edible essence fragrance.
Aforesaid operations step is both needed to carry out under the protection of inert gas, such as nitrogen, argon gas, helium etc., to prevent from producing The danger of green powder explosion.
It can be prepared into the classifications such as powdery, graininess, capsule shape, tablet shape, beverage according to the formula.
Application Example 1
50 progress blood lead analysis of -5 years old 1 years old infants are chosen, result is as follows:
Group 1 2
Blood lead range (μ g/L) 0~50 50~100
Number 28 22
The experimenter for choosing the lead doping in group 2 tests.
Test method: choosing nutrient powder prepared by above-described embodiment 1, and each 15mg is brewed with 90ml warm water, 3 times a day, It is continuous 14 days edible.
Experimenter after edible nutrient formulation of the present invention 14 days is re-started into blood lead analysis, blood lead concentration there are 15 people 50 μ g/L are dropped to hereinafter, remaining 7 people at least has dropped 5~10 μ g/L.
By above-mentioned test it is found that the lead discharging nutrient powder of embodiment 1 to reduce children's blood lead value have the function of it is obvious.
Specific embodiments of the present invention are described in detail above, but it is only used as example, the present invention is not intended to limit In particular embodiments described above.To those skilled in the art, the equivalent modifications and replace that any couple of present invention carries out In generation, is also all among scope of the invention.Therefore, without departing from the spirit and scope of the invention made by equal transformation and repair Change, all should be contained within the scope of the invention.

Claims (10)

1. a kind of children's lead discharging tailored version clinical nutrition formula, which is characterized in that including following component and its parts by weight: 25- 30 parts of protein, 0.2-2 parts of fat, 48-55 parts of carbohydrate, 8-12 parts of dietary fibers, 0.3-0.8 parts of macroelements, 0.1-0.25 parts of microelements, 0.01-0.05 parts of liposoluble vitamins, 0.15-0.3 parts of water soluble vitamins, 0.4-5 portions of diets Essence, 0.3-2.5 parts of integration of drinking and medicinal herbs ingredients and 0.2-0.5 parts of new resource foods；
Wherein, the protein includes concentrated whey protein powder, soybean protein isolate, bovine colostrum and amino acid；The fat Including Purple Perilla Seed Oil；The carbohydrate includes maltodextrin；The dietary fiber includes oligofructose and resistant dextrin；Institute Stating diet essence includes garlic powder, carrot meal, Kelp Powder, tremella powder, pork liver powder；The integration of drinking and medicinal herbs ingredient includes black sesame Fiber crops, cordate houttuynia, fructus lycii, endothelium corneum gigeriae galli.
2. a kind of children's lead discharging tailored version clinical nutrition formula according to claim 1, which is characterized in that the new resources Food includes first milk basic protein, hydrolysis yolk powder, γ-aminobutyric acid, chitosan oligosaccharide, eucommia Bark male flower, bamboo-leaves flavones, casein phosphorus Sour peptide, fish oil, avenabeta glucosan, Oligomeric manna sugar, Rosa roxburghii Tratt, Oligomeric manna sugar, yeast beta-dextran, newborn mineral salt, maca At least one of powder, Rosa roxburghii Tratt, xylo-oligosaccharide.
3. a kind of children's lead discharging tailored version clinical nutrition formula according to claim 1, which is characterized in that the amino acid Including 0.12 part of taurine.
4. a kind of children's lead discharging tailored version clinical nutrition formula according to claim 1, which is characterized in that the constant member Element includes calcium；The microelement includes iron and zinc.
5. a kind of children's lead discharging tailored version clinical nutrition formula according to claim 1, which is characterized in that described fat-soluble Vitamin includes vitamin A, beta carotene, vitamin D3, vitamin E；The water soluble vitamin includes vitamin B1, dimension Raw element B2, vitamin B6, vitamin B12, vitamin C, niacin, folic acid, pantothenic acid.
6. a kind of children's lead discharging tailored version clinical nutrition formula according to claim 1, which is characterized in that the medicine food is same Derived components include: 0.1-0.5 portions of Semen sesami nigrums, 0.1-0.5 portions of cordate houttuynias, 0.1-0.5 portions of fructus lyciis, 0.1-0.5 parts of endothelium corneum gigeriae gallis.
7. a kind of children's lead discharging tailored version clinical nutrition formula according to claim 1, which is characterized in that the clinical battalion Feeding formula further includes metallothionein, shrimp powder, black fungus powder and alginic acid, and parts by weight are 0.2~0.8 part.
8. a kind of children's lead discharging tailored version clinical nutrition formula according to claim 1, which is characterized in that the clinical battalion Supporting formula includes 50 portions of maltodextrins, 20 parts of concentrated whey protein powders, 6 parts of oligofructose, 6 parts of soybean protein isolates, 4 parts of resistances Dextrin, 0.2-2 parts of Purple Perilla Seed Oil microcapsule powders, 0.6 part of bovine colostrum, 0.1-1 parts of garlic powders, 0.1-1 parts of carrot meals, 0.1-1 Part Kelp Powder, 0.1-1 parts of tremella powder, 0.1-0.5 parts of pork liver powders, 0.1-0.5 portions of Semen sesami nigrums, 0.1-0.5 parts of cordate houttuynias, 0.1- 0.5 portion of fructus lycii, 0.1-0.5 parts of endothelium corneum gigeriae gallis, 0.4 part of Oligomeric manna sugar, 0.42 part of calcium, 0.018 part of iron, 0.016 part of zinc, 0.002 Part vitamin A, 0.005 part of beta carotene, 0.000002 part of vitamin D3, 0.016 part of vitamin E, 0.002 part of vitamin B1、 0.002 part of vitamin B2, 0.002 part of vitamin B6, 0.000004 part of vitamin B12, 0.2 part of vitamin C, 0.02 part of niacin, 0.0004 part of folic acid, 0.006 part of pantothenic acid, 0.12 part of taurine.
9. a kind of preparation method of such as children's lead discharging tailored version clinical nutrition formula according to any one of claims 1 to 8, It is characterized in that, includes the following steps:
The preparation of micro-capsule embedding techniques is respectively adopted simultaneously in the fat, liposoluble vitamin, water soluble vitamin of step (1) predetermined weight It crosses 60~80 meshes and powder is made；
The integration of drinking and medicinal herbs ingredient of step (2) predetermined weight is mentioned by crushing, alcohol extracting, water, is spray-dried and cross 60-80 mesh and is made Powder；
Remaining component of step (3) predetermined weight is prepared into the powder that partial size is 150~250 μm respectively；
Step (4) sterilizes powder prepared by step (1)~(3) spare after mixing；
Direct-edible pharmaceutical formulation is made in step (4) mixed powder by step (5)；
Wherein, step (1)~(3) sequence can be replaced mutually；The pharmaceutical formulation include nutrient powder, nutrition emulsion, capsule, Tablet, pill, oral solution.
10. the preparation method of children's lead discharging tailored version clinical nutrition formula described according to claim 1~any one of 8, It is characterized in that, includes the following steps:
Step 1) prepares the protein containing predetermined weight number, fat, carbohydrate, dietary fiber, macroelement, micro Element, vitamin, diet essence, integration of drinking and medicinal herbs ingredient and new resource food raw material powder pressed in the water of predetermined amount It according to the physical behavior of raw material, successively adds according to sequencing, is stirred while addition, the mixing cream of raw material is made Liquid；
The mixed emulsion that step 2) obtains step 1) carries out emulsifying homogeneous, concentrating sterilizing, obtains concentrate；
The concentrate that step 2) obtains is spray-dried by step 3), and sieving is prepared into powder, and above-mentioned powder is prepared into At least one of nutrient powder, nutrition emulsion, capsule, tablet, pill or oral solution.
CN201910267971.5A 2019-04-03 2019-04-03 A kind of children's lead discharging tailored version clinical nutrition formula and preparation method thereof Withdrawn CN109965272A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111956762A (en) * 2020-07-24 2020-11-20 恩施硒谷科技股份有限公司 Selenium-rich traditional Chinese medicine for promoting lead discharge and preparation method thereof
CN114158736A (en) * 2021-12-10 2022-03-11 青岛圣桐营养食品有限公司 Compound vitamin suitable for full-nutrition formula food with special medical application

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111956762A (en) * 2020-07-24 2020-11-20 恩施硒谷科技股份有限公司 Selenium-rich traditional Chinese medicine for promoting lead discharge and preparation method thereof
CN114158736A (en) * 2021-12-10 2022-03-11 青岛圣桐营养食品有限公司 Compound vitamin suitable for full-nutrition formula food with special medical application

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Application publication date: 20190705