CN108779160A - 施用工程化t细胞以治疗中枢神经系统中的癌症 - Google Patents

施用工程化t细胞以治疗中枢神经系统中的癌症 Download PDF

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CN108779160A
CN108779160A CN201780017442.9A CN201780017442A CN108779160A CN 108779160 A CN108779160 A CN 108779160A CN 201780017442 A CN201780017442 A CN 201780017442A CN 108779160 A CN108779160 A CN 108779160A
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cell
cells
amino acid
cancer
tumor
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B.巴迪
C.E.布朗
S.J.福曼
S.J.普赖斯曼
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City of Hope
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City of Hope
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CN201780017442.9A 2016-02-05 2017-02-06 施用工程化t细胞以治疗中枢神经系统中的癌症 Pending CN108779160A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662292152P 2016-02-05 2016-02-05
US62/292,152 2016-02-05
US201662309348P 2016-03-16 2016-03-16
US62/309,348 2016-03-16
PCT/US2017/016711 WO2017136829A1 (en) 2016-02-05 2017-02-06 Administration of engineered t cells for treatment of cancers in the central nervous system

Publications (1)

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CN108779160A true CN108779160A (zh) 2018-11-09

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CN201780017442.9A Pending CN108779160A (zh) 2016-02-05 2017-02-06 施用工程化t细胞以治疗中枢神经系统中的癌症

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Country Link
US (3) US20170224733A1 (https=)
EP (2) EP3411393B1 (https=)
JP (2) JP7189019B2 (https=)
KR (1) KR20180105709A (https=)
CN (1) CN108779160A (https=)
AU (2) AU2017213661B2 (https=)
BR (1) BR112018015836A2 (https=)
CA (1) CA3013773A1 (https=)
DK (1) DK3411393T3 (https=)
ES (1) ES2879700T3 (https=)
IL (2) IL287889B2 (https=)
MX (1) MX2023006304A (https=)
RU (1) RU2757308C2 (https=)
WO (1) WO2017136829A1 (https=)

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CN113646433A (zh) * 2020-07-16 2021-11-12 苏州博腾生物制药有限公司 靶向抗TNF-α抗体的组合物和方法
CN115551882A (zh) * 2020-01-31 2022-12-30 希望之城公司 用于治疗IL13Rα2阳性恶性病的靶向性嵌合抗原受体修饰的T细胞

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EP4282419A1 (en) 2012-12-20 2023-11-29 Purdue Research Foundation Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics
US10611837B2 (en) 2014-04-10 2020-04-07 Seattle Children's Hospital Transgene genetic tags and methods of use
AU2016306209B2 (en) 2015-08-07 2023-07-06 Seattle Children's Hospital (dba Seattle Children's Research Institute) Bispecific CAR T-cells for solid tumor targeting
IL287889B2 (en) 2016-02-05 2024-03-01 Hope City Administration of engineered t cells for treatment of cancers in the central nervous system
EP3439675A4 (en) 2016-04-08 2019-12-18 Purdue Research Foundation METHOD AND COMPOSITIONS FOR CAR-T CELL THERAPY
US11408005B2 (en) 2016-12-12 2022-08-09 Seattle Children's Hospital Chimeric transcription factor variants with augmented sensitivity to drug ligand induction of transgene expression in mammalian cells
WO2018160622A1 (en) 2017-02-28 2018-09-07 Endocyte, Inc. Compositions and methods for car t cell therapy
CN109971725B (zh) * 2017-12-28 2024-02-02 上海细胞治疗研究院 抗体修饰的嵌合抗原受体修饰t细胞及其用途
US11311576B2 (en) 2018-01-22 2022-04-26 Seattle Children's Hospital Methods of use for CAR T cells
AU2019225174B2 (en) 2018-02-23 2025-11-20 Endocyte, Inc. Sequencing method for CAR T cell therapy
EA202091984A1 (ru) * 2018-03-14 2021-02-18 Сиэтл Чилдрен'С Хоспитал (Дба Сиэтл Чилдрен'С Ресёрч Инститьют) Направленная дзетакинами т-клеточная иммунотерапия, нацеленная на рецептор il-13 альфа 2
EP3765041A4 (en) 2018-03-14 2021-12-22 Seattle Children's Hospital (DBA Seattle Children's Research Institute) IL-13 CHIMERIC RECEPTOR ALPHA 2 (IL13RA2) ANTIGEN RECEPTOR FOR T-CELL T-CELL IMMUNOTHERAPY
US20190284553A1 (en) 2018-03-15 2019-09-19 KSQ Therapeutics, Inc. Gene-regulating compositions and methods for improved immunotherapy
US12590133B2 (en) 2018-06-01 2026-03-31 The Board Of Trustees Of The Leland Stanford Junior University IL-13/IL-4 superkines: immune cell targeting constructs and methods of use thereof
JP2023520410A (ja) * 2020-03-31 2023-05-17 フレッド ハッチンソン キャンサー センター Ｃｄ３３を標的にするキメラ抗原受容体
CN115348973A (zh) 2020-03-31 2022-11-15 弗莱德哈钦森癌症中心 靶向cd33的嵌合抗原受体
JP2023550148A (ja) 2020-11-20 2023-11-30 シンシア・イノベーション・インコーポレイテッド がん免疫治療に用いられる武装二重ｃａｒ－ｔ組成物及び方法
CN117242090A (zh) * 2021-03-30 2023-12-15 希望之城公司 CAR T细胞疗法和IFNγ
WO2025235801A1 (en) 2024-05-08 2025-11-13 City Of Hope Antibodies targeted to osteopontin and uses thereof for reducing resistance of solid tumors immune cell therapy

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