CN108367102B - 用于来自生物流体的物料的过滤的切向流过滤器系统 - Google Patents

用于来自生物流体的物料的过滤的切向流过滤器系统 Download PDF

Info

Publication number
CN108367102B
CN108367102B CN201680058286.6A CN201680058286A CN108367102B CN 108367102 B CN108367102 B CN 108367102B CN 201680058286 A CN201680058286 A CN 201680058286A CN 108367102 B CN108367102 B CN 108367102B
Authority
CN
China
Prior art keywords
fluid
flow rate
filtration
permeate
retentate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201680058286.6A
Other languages
English (en)
Chinese (zh)
Other versions
CN108367102A (zh
Inventor
艾米丽·罗尔夫斯·迈林
盖里·西姆
阿比·瓦塞
本·克雷比尔
布莱克·赫斯托姆
亚伦·麦凯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferro Neuroscience Co ltd
Original Assignee
Minnetronix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Minnetronix Inc filed Critical Minnetronix Inc
Publication of CN108367102A publication Critical patent/CN108367102A/zh
Application granted granted Critical
Publication of CN108367102B publication Critical patent/CN108367102B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/58—Multistep processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/88—Draining devices having means for processing the drained fluid, e.g. an absorber
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/88—Draining devices having means for processing the drained fluid, e.g. an absorber
    • A61M1/884—Draining devices provided with means for filtering out the harmless water content before discarding the drainage container
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/145—Ultrafiltration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/147—Microfiltration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/149—Multistep processes comprising different kinds of membrane processes selected from ultrafiltration or microfiltration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/22—Controlling or regulating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/24—Dialysis ; Membrane extraction
    • B01D61/32—Controlling or regulating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0464—Cerebrospinal fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3327—Measuring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A61M2205/3334—Measuring or controlling the flow rate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/75—General characteristics of the apparatus with filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/11—Laminar flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/005—Parameter used as control input for the apparatus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M27/00—Drainage appliance for wounds or the like, i.e. wound drains, implanted drains
    • A61M27/002—Implant devices for drainage of body fluids from one part of the body to another
    • A61M27/006—Cerebrospinal drainage; Accessories therefor, e.g. valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2311/00—Details relating to membrane separation process operations and control
    • B01D2311/06—Specific process operations in the permeate stream
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2311/00—Details relating to membrane separation process operations and control
    • B01D2311/12—Addition of chemical agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2311/00—Details relating to membrane separation process operations and control
    • B01D2311/16—Flow or flux control
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2313/00—Details relating to membrane modules or apparatus
    • B01D2313/12—Specific discharge elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2313/00—Details relating to membrane modules or apparatus
    • B01D2313/18—Specific valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2315/00—Details relating to the membrane module operation
    • B01D2315/08—Fully permeating type; Dead-end filtration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2315/00—Details relating to the membrane module operation
    • B01D2315/10—Cross-flow filtration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2317/00—Membrane module arrangements within a plant or an apparatus
    • B01D2317/02—Elements in series
    • B01D2317/022—Reject series
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2317/00—Membrane module arrangements within a plant or an apparatus
    • B01D2317/04—Elements in parallel
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2317/00—Membrane module arrangements within a plant or an apparatus
    • B01D2317/08—Use of membrane modules of different kinds

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Water Supply & Treatment (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • External Artificial Organs (AREA)
  • Filtration Of Liquid (AREA)
CN201680058286.6A 2015-08-05 2016-06-09 用于来自生物流体的物料的过滤的切向流过滤器系统 Active CN108367102B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562201287P 2015-08-05 2015-08-05
US62/201,287 2015-08-05
PCT/US2016/036626 WO2017023419A1 (en) 2015-08-05 2016-06-09 Tangential flow filter system for the filtration of materials from biologic fluids

Publications (2)

Publication Number Publication Date
CN108367102A CN108367102A (zh) 2018-08-03
CN108367102B true CN108367102B (zh) 2021-04-30

Family

ID=57943990

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201680058286.6A Active CN108367102B (zh) 2015-08-05 2016-06-09 用于来自生物流体的物料的过滤的切向流过滤器系统

Country Status (8)

Country Link
US (4) US12364952B2 (enExample)
EP (2) EP3714915B1 (enExample)
JP (2) JP7166915B2 (enExample)
CN (1) CN108367102B (enExample)
AU (3) AU2016304020B2 (enExample)
CA (1) CA2994669C (enExample)
ES (2) ES2906952T3 (enExample)
WO (1) WO2017023419A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10632237B2 (en) 2006-10-09 2020-04-28 Minnetronix, Inc. Tangential flow filter system for the filtration of materials from biologic fluids
ES2906952T3 (es) 2015-08-05 2022-04-21 Minnetronix Inc Sistema de filtro de flujo tangencial para la filtración de materiales a partir de fluidos biológicos
US20190105475A1 (en) * 2017-10-05 2019-04-11 Minnetronix, Inc. Systems, catheters, and methods for treating along the central nervous system
AU2019298242B2 (en) * 2018-07-02 2022-09-15 Pharaoh Neuro, Inc. Systems, catheters, and methods for treating along the central nervous system
EP4574196A3 (en) * 2018-08-08 2025-09-03 Minnetronix Neuro, Inc. Systems, catheters, and methods for treating along the central nervous system
ES3039528T3 (en) 2020-02-03 2025-10-22 Minnetronix Neuro Inc Systems for treating along the central nervous system
CA3183415A1 (en) * 2020-05-11 2021-11-18 Minnetronix Neuro, Inc. Filtering cassettes and filtering systems
US20230211265A1 (en) * 2021-12-31 2023-07-06 Pall Corporation Bulk fill system with serial fluid filtration assembly and method of using same for automated air transfer

Citations (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4904237A (en) * 1988-05-16 1990-02-27 Janese Woodrow W Apparatus for the exchange of cerebrospinal fluid and a method of treating brain and spinal cord injuries
US5897528A (en) * 1998-04-30 1999-04-27 Medtronic, Inc. Filtered intracerebroventricular or intraspinal access port with direct cerebrospinal fluid access
CN1110369C (zh) * 1994-11-14 2003-06-04 宾夕法尼亚州大学信托人 用于测定和加工分析物的中尺度样品制备设备和系统
CN1433328A (zh) * 1999-12-03 2003-07-30 神经原治疗公司 人造脑脊液的闭合再循环的方法和设备
EP0921836B1 (en) * 1996-07-11 2004-05-12 Eunoe, Inc. Apparatus for treating adult-onset dementia of the alzheimer's type
EP1600186A1 (en) * 1999-03-03 2005-11-30 UAB Research Foundation Direct central nervous system catheter and temperature control system
WO2008105959A2 (en) * 2006-10-09 2008-09-04 Neurofluidics, Inc. Cerebrospinal fluid purification system
CN101415482A (zh) * 2006-03-31 2009-04-22 金克克国际有限公司 用于化合物分离的切向流动过滤设备、系统和方法
CN101801431A (zh) * 2007-06-22 2010-08-11 循环生物制品有限责任公司 流体浓缩器和自体浓缩体液及其使用方法
WO2010123558A1 (en) * 2009-04-22 2010-10-28 Neurofluidics, Inc. Programmable system for conditioning of cerebrospinal fluid
US20110098623A1 (en) * 2008-06-17 2011-04-28 Georgia Tech Research Corporation Device and method of using superparamagnetic nanoparticles in treatment and removal of cells
US20120234694A1 (en) * 2011-01-25 2012-09-20 President And Fellows Of Harvard College Electrochemical carbon nanotube filter and method
US20150094644A1 (en) * 2013-10-01 2015-04-02 Md Start Sa Systems and methods for moving and circulating fluid to treat alzheimer's disease
CN204352261U (zh) * 2014-12-31 2015-05-27 李思成 主要用于在脑科手术使用的改良型吸引装置
US20150328295A1 (en) * 2014-05-15 2015-11-19 Washington University Vaccination against Cryptococcus

Family Cites Families (246)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2969066A (en) 1956-10-02 1961-01-24 Holter Company Device for draining ventricular fluid in cases of hydrocephalus
US3419010A (en) 1966-01-17 1968-12-31 Cordis Corp Catheter
US3867937A (en) 1972-12-07 1975-02-25 Boris Schwartz Flexible protective sheath for catheter
US3889687A (en) 1974-01-31 1975-06-17 Donald L Harris Shunt system for the transport of cerebrospinal fluid
US4830849A (en) 1980-04-14 1989-05-16 Thomas Jefferson University Extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
US4378797A (en) 1980-04-14 1983-04-05 Thomas Jefferson University Extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
US4686085A (en) 1980-04-14 1987-08-11 Thomas Jefferson University Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
US4446154A (en) 1982-03-03 1984-05-01 Thomas Jefferson University Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
US4451251A (en) 1982-03-03 1984-05-29 Thomas Jefferson University Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders
US4551137A (en) 1982-10-07 1985-11-05 Cook Incorporated Flexible sheath assembly for an indwelling catheter
US4767409A (en) 1983-05-23 1988-08-30 Edward Weck Incorporated Catheter protective shield
US4888115A (en) 1983-12-29 1989-12-19 Cuno, Incorporated Cross-flow filtration
US4695541A (en) 1985-01-31 1987-09-22 Molecular Diagnostics, Inc. Enzymatic detection of bacterial capsular polysaccharide antigens
US4902276A (en) 1986-06-09 1990-02-20 The Regents Of The University Of California Apparatus and method for removing obstructions in bodily organs or cavities
US6022742A (en) 1986-11-26 2000-02-08 Kopf; Henry B. Culture device and method
US4958901A (en) 1987-07-13 1990-09-25 Neurodelivery Technology, Inc. Method for making a multi-lumen epidural-spinal needle and tip and stock configuration for the same
US4950232A (en) 1987-08-11 1990-08-21 Surelab Superior Research Laboratories Cerebrospinal fluid shunt system
US5948441A (en) 1988-03-07 1999-09-07 The Liposome Company, Inc. Method for size separation of particles
US4973312A (en) 1989-05-26 1990-11-27 Andrew Daniel E Method and system for inserting spinal catheters
EP0478842A1 (de) 1990-10-05 1992-04-08 PALL BIOMEDIZIN GmbH Filter zur Filtration menschlicher Cerebronspinalflüssigkeit
US5190529A (en) 1991-05-20 1993-03-02 The Kendall Company Advancement sleeve and adapter for a catheter
US5171226A (en) 1991-05-20 1992-12-15 The Kendall Company Method of long term epidural catherization
US5143630A (en) * 1991-05-30 1992-09-01 Membrex, Inc. Rotary disc filtration device
CA2074671A1 (en) 1991-11-04 1993-05-05 Thomas Bormann Device and method for separating plasma from a biological fluid
US5334315A (en) 1992-01-17 1994-08-02 Pall Corporation Priming system
US5423738A (en) 1992-03-13 1995-06-13 Robinson; Thomas C. Blood pumping and processing system
US5726026A (en) * 1992-05-01 1998-03-10 Trustees Of The University Of Pennsylvania Mesoscale sample preparation device and systems for determination and processing of analytes
US5755968A (en) 1992-07-30 1998-05-26 Stone; Andrew Dialysis system and method for removing toxic matter from the serum of the large intestine
US6620188B1 (en) 1998-08-24 2003-09-16 Radiant Medical, Inc. Methods and apparatus for regional and whole body temperature modification
US5396899A (en) 1993-04-28 1995-03-14 Duke University Spinal puncture fluid collection apparatus
NL9301653A (nl) 1993-09-24 1995-04-18 X Flow Bv Werkwijze voor het verwijderen van troebelheid veroorzakende bestanddelen uit een vloeistof met behulp van microfiltratie.
NL9301716A (nl) 1993-10-06 1995-05-01 X Flow Bv Microfiltratie- en/of ultrafiltratiemembraan, werkwijze voor de bereiding van een dergelijk membraan, alsmede werkwijze voor het filtreren van een vloeistof met behulp van een dergelijk membraan.
US5405316A (en) 1993-11-17 1995-04-11 Magram; Gary Cerebrospinal fluid shunt
US6716216B1 (en) 1998-08-14 2004-04-06 Kyphon Inc. Systems and methods for treating vertebral bodies
RU2100965C1 (ru) 1994-08-31 1998-01-10 Научно-исследовательский институт неврологии РАМН Способ лечения кровоизлияний в мозг и устройство для его осуществления
US7069634B1 (en) 1995-04-28 2006-07-04 Medtronic, Inc. Method for manufacturing a catheter
US5531673A (en) 1995-05-26 1996-07-02 Helenowski; Tomasz K. Ventricular catheter
US5772607A (en) 1995-06-06 1998-06-30 The Nemours Foundation Body fluid collection apparatus
EP0871539B1 (en) 1995-06-16 2002-02-20 University of Washington Tangential flow planar microfabricated fluid filter
US5683357A (en) 1995-12-01 1997-11-04 Magram; Gary External cerebrospinal fluid drain apparatus
US5846220A (en) 1996-04-30 1998-12-08 Medtronic, Inc. Therapeutic method for treatment of Alzheimer's disease
US20030004495A1 (en) 1996-07-11 2003-01-02 Eunoe, Inc. Apparatus and methods for volumetric CSF removal
US6383159B1 (en) 1998-11-10 2002-05-07 Eunoe, Inc. Devices and method for removing cerebrospinal fluids from a patient's CSF space
US6689085B1 (en) 1996-07-11 2004-02-10 Eunoe, Inc. Method and apparatus for treating adult-onset dementia of the Alzheimer's type
EP0824894B1 (en) 1996-08-16 2003-03-12 Smiths Group PLC Needle assemblies
CA2186963C (en) 1996-10-01 1999-03-30 Riad A. Al-Samadi High water recovery membrane purification process
US5836928A (en) 1997-02-04 1998-11-17 Gerber; Allen Spinal fluid collection system
US6326044B1 (en) * 1997-06-19 2001-12-04 Tetra Laval Holdings & Finance S.A. Filter apparatus and method for the production of sterile skimmed milk
US5947689A (en) 1997-05-07 1999-09-07 Scilog, Inc. Automated, quantitative, system for filtration of liquids having a pump controller
US20020198487A1 (en) 2001-04-10 2002-12-26 Renal Tech International Devices, systems, and methods for reducing levels of pro-inflammatory or anti-inflammatory stimulators or mediators in physiologic fluids
US6030358A (en) 1997-08-08 2000-02-29 Odland; Rick Matthew Microcatheter and method for site specific therapy
DE20103363U1 (de) 2001-02-26 2001-05-17 Braun Melsungen Ag Schutzvorrichtung für eine Injektionsnadel
RU2158613C2 (ru) 1997-08-20 2000-11-10 Иркутский институт усовершенствования врачей Способ лечения повреждений центральной нервной системы
US6066149A (en) 1997-09-30 2000-05-23 Target Therapeutics, Inc. Mechanical clot treatment device with distal filter
US6295990B1 (en) 1998-02-03 2001-10-02 Salient Interventional Systems, Inc. Methods and systems for treating ischemia
EP1083836B1 (en) 1998-06-01 2010-10-13 Kyphon SÀRL Expandable preformed structures for deployment in interior body regions
US6013051A (en) 1998-10-22 2000-01-11 Medtronic, Inc. Filtered access port with filter bypass for accessing body fluid samples
US6875192B1 (en) * 1998-11-10 2005-04-05 Eunoe, Inc. Devices and methods for removing cerebrospinal fluids from a patient's CSF space
US7189221B2 (en) 1998-11-10 2007-03-13 Integra Life Sciences Corporation Methods for the treatment of a normal pressure hydrocephalus
US6165199A (en) 1999-01-12 2000-12-26 Coaxia, Inc. Medical device for removing thromboembolic material from cerebral arteries and methods of use
US6161547A (en) 1999-01-15 2000-12-19 Coaxia, Inc. Medical device for flow augmentation in patients with occlusive cerebrovascular disease and methods of use
AU2225600A (en) 1999-01-21 2000-08-07 Thomas M. Kennedy Sheath, epidural catheter system, and method for inserting catheter
DK1154827T3 (da) 1999-02-22 2007-02-19 Ncsrt Inc Oprensning af biologiske stoffer
US6217552B1 (en) 1999-03-01 2001-04-17 Coaxia, Inc. Medical device for selective intrathecal spinal cooling in aortic surgery and spinal trauma
ATE308353T1 (de) 1999-03-03 2005-11-15 Uab Research Foundation Für das zentrale nervensystem bestimmer katheter mit temperaturkontrollsystem
DE60025716T2 (de) 1999-04-30 2006-10-19 Children's Hospital Medical Center, Cincinnati Hämofiltrationssystem
US6849185B1 (en) 1999-05-14 2005-02-01 Pall Corp Charged membrane
US6238382B1 (en) 1999-08-19 2001-05-29 Datascope Investment Corp. Intra-aortic balloon catheter having a tapered Y-fitting
WO2001054766A1 (en) 2000-01-27 2001-08-02 Eunoe, Inc. Systems and methods for exchanging cerebrospinal fluid
US7181289B2 (en) 2000-03-20 2007-02-20 Pflueger D Russell Epidural nerve root access catheter and treatment methods
CA2404430A1 (en) 2000-04-07 2001-10-18 Albert S. Lee Methods and apparatus for thermally affecting tissue
US6468219B1 (en) 2000-04-24 2002-10-22 Philip Chidi Njemanze Implantable telemetric transcranial doppler device
US6447500B1 (en) 2000-04-28 2002-09-10 Medtronic, Inc. Brain fluid ion concentration modification for treating neurological disorders
US8133698B2 (en) * 2000-05-15 2012-03-13 Silver James H Sensors for detecting substances indicative of stroke, ischemia, infection or inflammation
EP1289437A1 (en) 2000-05-31 2003-03-12 Hussain Karim Epidural apparatus
US6350382B1 (en) 2000-06-23 2002-02-26 Scilog, Inc. Enhancing filtration yields in tangential flow filtration
US6607669B2 (en) 2000-06-23 2003-08-19 Scilog, Inc. Method and apparatus for enhancing filtration yields in tangential flow filtration
EP1174177A3 (en) 2000-07-18 2002-12-04 Nitto Denko Corporation Spiral wound membrane element, spiral wound membrane module and treatment system employing the same as well as running method and washing method therefor
GB2365344A (en) 2000-08-04 2002-02-20 Alan David Mogg Catheter adaptor
US6497699B1 (en) 2000-08-09 2002-12-24 The Research Foundation Of State University Of New York Hybrid neuroprosthesis for the treatment of brain disorders
PT1324800E (pt) 2000-09-11 2008-10-14 Csf Dynamics As Sistema de derivação de fluidos para o tratamento de hidrocefalia
GR1003723B (el) 2000-10-19 2001-11-19 Αθανασιου Χρηστος Πανοτοπουλος Καθετηρας πολλαπλων εφαρμογων
US6641563B1 (en) 2000-11-01 2003-11-04 Arrow International, Inc. Stylet-free epidural catheter and thread assist device
US6602241B2 (en) 2001-01-17 2003-08-05 Transvascular, Inc. Methods and apparatus for acute or chronic delivery of substances or apparatus to extravascular treatment sites
US6558353B2 (en) 2001-01-25 2003-05-06 Walter A. Zohmann Spinal needle
US6689756B2 (en) 2001-03-02 2004-02-10 Integra Lifesciences Corporation Treatment of neurological disease
US20020193285A1 (en) 2001-03-02 2002-12-19 Hesson David P. Neuroprotectants formulations and methods
WO2002085431A2 (en) 2001-04-24 2002-10-31 Neuron Therapeutics, Inc. Method of delivering liquid through cerebral spinal pathway
US6699269B2 (en) 2001-04-30 2004-03-02 Rohit K. Khanna Selective brain and spinal cord hypothermia method and apparatus
US20030028137A1 (en) 2001-05-18 2003-02-06 Levin Bruce H. Novel hypothermic modalities and direct application of protective agents to neural structures or into CSF
US7011647B2 (en) 2001-07-13 2006-03-14 Scimed Life Systems, Inc. Introducer sheath
US7150737B2 (en) 2001-07-13 2006-12-19 Sci/Med Life Systems, Inc. Methods and apparatuses for navigating the subarachnoid space
US20030093105A1 (en) 2001-07-13 2003-05-15 Scimed Life Systems, Inc. Guide catheter for introduction into the subarachnoid space and methods of use thereof
US7455666B2 (en) 2001-07-13 2008-11-25 Board Of Regents, The University Of Texas System Methods and apparatuses for navigating the subarachnoid space
US7025739B2 (en) 2001-08-09 2006-04-11 Integra Lifesciences Corporation System and method for treating elevated intracranial pressure
WO2003015710A2 (en) 2001-08-21 2003-02-27 Eunoe, Inc. Combined drug and csf removal therapies and systems
AU2002335658A1 (en) 2001-08-31 2003-03-18 Neuron Therapeutics, Inc. Treatment of neurologic hemorrhage
US6683066B2 (en) 2001-09-24 2004-01-27 Yanming Wang Composition and treatment method for brain and spinal cord injuries
AU2002329570A1 (en) 2001-10-12 2003-01-30 Pfizer Products Inc. Method of monitoring neuroprotective treatment
US20030072761A1 (en) 2001-10-16 2003-04-17 Lebowitz Jonathan Methods and compositions for targeting proteins across the blood brain barrier
US7308303B2 (en) 2001-11-01 2007-12-11 Advanced Bionics Corporation Thrombolysis and chronic anticoagulation therapy
US20030163181A1 (en) 2001-12-07 2003-08-28 Neuron Therapeutics, Inc. Protection of neurological tissue by direct CNS perfusion cooling
US7156867B2 (en) 2001-12-31 2007-01-02 Medcool, Inc. Uniform selective cerebral hypothermia
US6953444B2 (en) 2002-01-24 2005-10-11 Codman & Shurtleff, Inc. Inherent anti-siphon device
US7108680B2 (en) 2002-03-06 2006-09-19 Codman & Shurtleff, Inc. Closed-loop drug delivery system
WO2003089031A1 (en) 2002-04-19 2003-10-30 Neuron Therapeutics Subarachnoid spinal catheter for transporting cerebrospinal fluid
US6830561B2 (en) 2002-05-08 2004-12-14 Scimed Life Systems, Inc. Catheter with protective sleeve
HUE031517T2 (en) 2002-06-19 2017-07-28 Northwest Biotherapeutics Inc Cross-flow filtration equipment and procedures for leukocyte enrichment
US6969383B2 (en) 2002-09-27 2005-11-29 Medtronic, Inc. Method for treating severe tinnitus
US7632413B2 (en) 2002-11-04 2009-12-15 Ashland Licensing And Intellectual Property Llc Process for treating a liquid medium using ultrasound
CA2411569A1 (en) 2002-11-12 2004-05-12 Ross E. Mantle Medical device for the extravascular recirculation of fluid in body cavities at controlled temperature and pressure
EP1581285B1 (en) 2002-12-23 2009-02-25 Medtronic, Inc. Drug solution density adjustment systems and methods
US7004961B2 (en) 2003-01-09 2006-02-28 Edward Wong Medical device and method for temperature control and treatment of the brain and spinal cord
JP2004236792A (ja) 2003-02-05 2004-08-26 Toray Ind Inc 糖尿病合併症因子吸着体
WO2004072647A1 (en) 2003-02-07 2004-08-26 Beyond Genomics Removal of proteins from a sample
US7267671B2 (en) 2003-02-07 2007-09-11 Alfred E. Mann Institute For Biomedical Research At The University Of Southern California Surgical drain with sensors for monitoring fluid lumen
US7963956B2 (en) 2003-04-22 2011-06-21 Antisense Pharma Gmbh Portable equipment for administration of fluids into tissues and tumors by convection enhanced delivery technique
US7241283B2 (en) 2003-04-25 2007-07-10 Ad-Tech Medical Instrument Corp. Method for intracranial catheter treatment of brain tissue
ATE460194T1 (de) 2003-05-29 2010-03-15 Renishaw Ireland Ltd Implantierbare pumpe
US20050004504A1 (en) 2003-06-24 2005-01-06 Frye Mark R. Catheter for extracorporeal treatment
US7220252B2 (en) 2003-07-18 2007-05-22 Polyzen, Inc. Inflatable dual balloon catheter
US8340779B2 (en) 2003-08-29 2012-12-25 Medtronic, Inc. Percutaneous flat lead introducer
US20050085826A1 (en) 2003-10-21 2005-04-21 Scimed Life Systems, Inc. Unfolding balloon catheter for proximal embolus protection
US20050090801A1 (en) 2003-10-27 2005-04-28 Racz N. S. Safety spinal catheter
US7118549B2 (en) 2003-10-31 2006-10-10 Codman & Shurtleff, Inc. Shunt system including a flow control device for controlling the flow of cerebrospinal fluid out of a brain ventricle
US7807777B2 (en) 2003-11-05 2010-10-05 Immuno-Biological Laboratories Co., Ltd. Marker peptide for alzheimer's disease
US7318834B2 (en) 2004-02-09 2008-01-15 Philip Chidi Njemanze Apparatus and method for hypothermia and rewarming by altering the temperature of the cerebrospinal fluid in the brain
US20060015160A1 (en) 2004-07-19 2006-01-19 Seacoast Technologies, Inc. Method and apparatus for cooling spinal cord and fluid
CA2574679C (en) 2004-07-20 2013-06-04 Medtronic, Inc. Implantable cerebral spinal fluid drainage device and method of draining cerebral spinal fluid
US20060016751A1 (en) 2004-07-23 2006-01-26 Rayonier Products And Financial Services Company Method of concentrating pulp mill extracts
US20060030027A1 (en) 2004-08-04 2006-02-09 Aspira Biosystems, Inc. Capture and removal of biomolecules from body fluids using partial molecular imprints
US7993580B2 (en) 2004-08-24 2011-08-09 Baxter International Inc. Methods for the inactivation of microorganisms in biological fluids, flow through reactors and methods of controlling the light sum dose to effectively inactivate microorganisms in batch reactors
US8366735B2 (en) 2004-09-10 2013-02-05 Penumbra, Inc. System and method for treating ischemic stroke
WO2006079007A2 (en) 2005-01-21 2006-07-27 President And Fellows Of Harvard College Microconcentrator/microfilter
US20060175543A1 (en) 2005-02-08 2006-08-10 John Elefteriades Intra-thecal catheter and method for cooling the spinal cord
US20060224102A1 (en) 2005-04-05 2006-10-05 Codman & Shurtleff, Inc Subarachnoid epidural shunt
RU2290974C1 (ru) 2005-04-11 2007-01-10 Ростовский научно-исследовательский онкологический институт МЗ РФ Способ лечения онкологических больных с метастатическим поражением головного мозга
US20060254984A1 (en) 2005-05-16 2006-11-16 Uspolyresearch Hollow Fiber Membrane Adsorber and Process for the Use Thereof
US20060282043A1 (en) 2005-06-14 2006-12-14 Pyles Stephen T Intrathecal catheter having a stylet with a curved tip
US20120330196A1 (en) 2005-06-24 2012-12-27 Penumbra Inc. Methods and Apparatus for Removing Blood Clots and Tissue from the Patient's Head
WO2007013945A2 (en) 2005-07-20 2007-02-01 The Regents Of The University Of California Treating disorders associated with inflammation
US7993821B2 (en) 2005-08-11 2011-08-09 University Of Washington Methods and apparatus for the isolation and enrichment of circulating tumor cells
GR20050100452A (el) 2005-09-02 2007-04-25 Estelle Enterprises Limited Συστημα καθετηρα ανταλλαγης υγρων
RU2314838C2 (ru) 2005-09-19 2008-01-20 ГУ Научный Центр реконструктивной и восстановительной хирургии ВСНЦ СО РАМН (ГУ НЦ РВХ ВСНЦ СО РАМН) Способ лечения внутримозговых кровоизлияний
US7850723B1 (en) 2005-11-28 2010-12-14 Innercool Therapies, Inc. Method and apparatus for patient temperature control employing titration of therapy using EEG signals
US7674240B2 (en) 2005-12-20 2010-03-09 Abbott Cardiovascular Systems Inc. Method and apparatus for controlled vessel occlusion
GB2436527B (en) 2006-03-29 2008-02-20 Zsolt Joel Szarka Needle
US20080154181A1 (en) 2006-05-05 2008-06-26 Khanna Rohit K Central nervous system ultrasonic drain
US9770180B2 (en) 2006-08-17 2017-09-26 Milan Radojicic System and method for monitoring and delivering therapeutics to the spinal cord
US20080045883A1 (en) 2006-08-17 2008-02-21 Milan Radojicic Devices and methods for monitoring and delivering therapeutics to the spinal cord
US8231586B2 (en) 2006-09-15 2012-07-31 Creighton University Cerebrospinal fluid collection tubes and methods
US20160051801A1 (en) 2014-08-19 2016-02-25 Minnetronix, Inc. Devices and Systems for Access and Navigation of Cerebrospinal Fluid Space
US10850235B2 (en) 2006-10-09 2020-12-01 Minnetronix, Inc. Method for filtering cerebrospinal fluid (CSF) including monitoring CSF flow
US10569064B2 (en) 2013-03-13 2020-02-25 Minnetronix, Inc. Devices and methods for providing focal cooling to the brain and spinal cord
US10632237B2 (en) 2006-10-09 2020-04-28 Minnetronix, Inc. Tangential flow filter system for the filtration of materials from biologic fluids
US10695545B2 (en) 2006-10-09 2020-06-30 Minnetronix, Inc. Systems and methods for the conditioning of cerebrospinal fluid
US7776003B2 (en) 2006-10-28 2010-08-17 Alois Zauner Multimodal catheter for focal brain monitoring and ventriculostomy
RU2312678C1 (ru) 2006-12-12 2007-12-20 Государственное образовательное учреждение дополнительного профессионального образования "Иркутский государственный институт усовершенствования врачей" Федерального агентства по здравоохранению и социальному развитию Способ экстракорпоральной очистки цереброспинальной жидкости при заболеваниях нервной системы
US8529761B2 (en) 2007-02-13 2013-09-10 Fluid Equipment Development Company, Llc Central pumping and energy recovery in a reverse osmosis system
KR20090121297A (ko) 2007-03-02 2009-11-25 스미쓰 앤드 네퓨 피엘씨 생물학적 시료의 여과시 초음파, 역세정 및 필터 이동에 의한 필터 세정용 기기 및 방법
US20080249458A1 (en) 2007-04-09 2008-10-09 Medtronic Vascular, Inc. Intraventricular Shunt and Methods of Use Therefor
US20080249501A1 (en) 2007-04-09 2008-10-09 Medtronic Vascular, Inc. Methods for Simultaneous Injection and Aspiration of Fluids During a Medical Procedure
CA2686319C (en) * 2007-05-25 2012-11-13 Gambro Lundia Ab A device for connecting to a liquid source
US7967867B2 (en) 2007-05-31 2011-06-28 Spine Wave, Inc. Expandable interbody fusion device
MX338096B (es) 2007-06-06 2016-04-01 Héctor De Jesús Velez Rivera Aguja espinal con una camara para identificar el liquido cefalorraquideo.
PL2170181T3 (pl) 2007-06-22 2014-08-29 Ekos Corp Sposób i aparat do leczenia wylewów wewnątrzczaszkowych
US7793957B2 (en) 2007-06-29 2010-09-14 Kayaba Industry Co., Ltd. Steering damping device
CA2693139C (en) 2007-07-16 2016-08-23 C.R. Bard, Inc. Foley catheter having sterile barrier
US20140194840A1 (en) 2007-08-25 2014-07-10 Beckersmith Medical, Inc. Portable automated body fluid drain control apparatus
DK2190497T3 (en) 2007-08-25 2014-03-24 Beckersmith Medical Inc APPARATUS FOR AUTOMATED CONTROL OF DRAINAGE OF BODY FLUIDS
US8221366B2 (en) 2007-09-05 2012-07-17 Integra Lifesciences Corporation Volume limiting bodily fluid drainage system
US9034007B2 (en) 2007-09-21 2015-05-19 Insera Therapeutics, Inc. Distal embolic protection devices with a variable thickness microguidewire and methods for their use
US8357296B2 (en) 2007-09-24 2013-01-22 Emd Millipore Corporation Centrifugal filter
US9198687B2 (en) 2007-10-17 2015-12-01 Covidien Lp Acute stroke revascularization/recanalization systems processes and products thereby
US7887503B2 (en) 2007-11-20 2011-02-15 Mark Geiger Method and apparatus for removing harmful proteins from a mammalian's ventricular cerebrospinal fluid
CA2710831A1 (en) 2007-12-27 2009-07-09 Wilson-Cook Medical, Inc. Two-part extraction balloon
JP2011519361A (ja) * 2008-04-14 2011-07-07 ハロザイム インコーポレイテッド 修飾されたヒアルロニダーゼおよびヒアルロナン関連疾患および状態の治療における使用
WO2009140202A1 (en) 2008-05-12 2009-11-19 Cardionephrx, Inc. Implantable fluid separation system
CN100577222C (zh) 2008-05-22 2010-01-06 中国人民解放军第三军医大学第三附属医院 一种颅内血肿清除后残存有害成分的吸附引流装置
US7799016B2 (en) 2008-06-20 2010-09-21 Pharmaco-Kinesis Corporation Magnetic breather pump and a method for treating a brain tumor using the same
US8070694B2 (en) 2008-07-14 2011-12-06 Medtronic Vascular, Inc. Fiber based medical devices and aspiration catheters
WO2010014447A2 (en) 2008-07-29 2010-02-04 University Of Maryland, Baltimore Embolectomy stroke device
EP2320987A1 (en) 2008-07-29 2011-05-18 Medtronic, Inc. Apheresis of a target molecule from cerebrospinal fluid
US8163123B2 (en) 2008-07-31 2012-04-24 Boston Scientific Scimed, Inc. Bifurcation catheter dual balloon bond and methods
US7951110B2 (en) 2008-11-10 2011-05-31 Onset Medical Corporation Expandable spinal sheath and method of use
US20110029050A1 (en) 2008-11-18 2011-02-03 John Elefteriades Intra-ventricular brain cooling catheter
US20100168665A1 (en) 2008-12-30 2010-07-01 Wilson-Cook Medical Inc. Segmented balloon for catheter tip deflection
US9156037B2 (en) 2009-01-15 2015-10-13 Children's Medical Center Corporation Microfluidic device and uses thereof
US20100204672A1 (en) 2009-02-12 2010-08-12 Penumra, Inc. System and method for treating ischemic stroke
US8905968B2 (en) 2009-04-29 2014-12-09 Encephalon Technologies, Llc System for cooling and pressurizing fluid
US20100280438A1 (en) 2009-04-29 2010-11-04 Dr. Jeffrey E. Thomas Bidirectional cerebral spinal fluid infusion catheter with cooling mechanism and method of use
CN102802717A (zh) 2009-06-19 2012-11-28 贝尼奇尔股份有限公司 用于使鼻腔降温的设备
CN101653637B (zh) 2009-08-03 2012-05-23 方乃成 弹头形脑科多孔引流管及采用该引流管的脑科引流装置
US20120296166A1 (en) 2009-11-13 2012-11-22 Kim Daniel H Intradural endoscope
JP5624629B2 (ja) 2009-12-23 2014-11-12 サイトベラ，インコーポレイテッド 粒子を濾過するためのシステム及び方法
US20110190831A1 (en) 2010-01-29 2011-08-04 Kyphon Sarl Steerable balloon catheter
WO2011114260A1 (en) * 2010-03-19 2011-09-22 Pfizer Inc. Cerebrospinal fluid purification system
US9662478B2 (en) 2010-03-19 2017-05-30 University Of Washington Body fluid drainage system
US20120302938A1 (en) 2010-03-19 2012-11-29 University Of Washington Drainage systems for excess body fluids and associated methods
CA2799473C (en) 2010-05-14 2020-03-10 Todd Sheppard Saunders Methods and devices for cooling spinal tissue
US8894584B2 (en) 2010-05-28 2014-11-25 Shuntcheck, Inc. Real time CSF flow measurement system and method
IN2013MN00105A (enExample) 2010-06-13 2015-05-29 Omeq Medical Ltd
US10888657B2 (en) 2010-08-27 2021-01-12 Ekos Corporation Method and apparatus for treatment of intracranial hemorrhages
US9211163B1 (en) 2010-10-26 2015-12-15 Branislav Jaramaz Apparatus and method for minimally invasive intracranial hematoma evacuation with real-time assessment of clot reduction
WO2012066376A1 (en) 2010-11-18 2012-05-24 Centre National De La Recherche Scientifique - Cnrs - Inhibitors of apoptosis and uses thereof
WO2012099984A1 (en) 2011-01-18 2012-07-26 Innerspace, Inc. Stylet that senses csf
US9550041B2 (en) 2011-02-04 2017-01-24 Advanced Pain Center, Llc. Continuous single wire steerable catheter
US20120203290A1 (en) 2011-02-04 2012-08-09 Interventional Spine, Inc. Method and apparatus for spinal fixation
US9220829B2 (en) 2011-03-09 2015-12-29 Zvi Herschman Implantable systems and methods for removing specific impurities from fluids such as blood
US9375522B2 (en) 2011-04-04 2016-06-28 Adnan Iqbal Qureshi Extradural infusion suction system and method to drain fluid collection in the extradural space of spinal cord
CA2841863A1 (en) 2011-07-25 2013-01-31 Neurosave, Inc. Non-invasive systems, devices, and methods for selective brain cooling
WO2013022796A2 (en) 2011-08-05 2013-02-14 Silk Road Medical, Inc. Methods and systems for treatment of acute ischemic stroke
US9402982B2 (en) 2011-09-05 2016-08-02 Steerable Instruments Bvba Minimally-advancing luminal catheter
US20130066331A1 (en) 2011-09-14 2013-03-14 Nevro Corporation Tapered, curved stylets for inserting spinal cord modulation leads and associated systems and methods
US20130126430A1 (en) 2011-09-15 2013-05-23 Deka Products Limited Partnership Systems, Apparatus, and Methods for a Water Purification System
US9345826B2 (en) 2011-09-15 2016-05-24 Deka Products Limited Partnership Recirculating fluid filtration system
WO2013052951A2 (en) 2011-10-07 2013-04-11 The Trustees Of Columbia University In The City Of New York Fluid component separation devices, methods, and systems
CA2852220A1 (en) 2011-10-14 2013-07-18 Cytopherx, Inc. Cartridge and method for increasing myocardial function
CN202409608U (zh) 2011-11-30 2012-09-05 卢天喜 一次性硬脑膜下置管引流套件
CN104114104B (zh) 2011-12-08 2016-12-07 华盛顿大学商业中心 超声探针
EP2695632A1 (en) 2012-08-10 2014-02-12 Irras AB Fluid exchange catheter and process for unblocking a fluid exchange catheter
EP2695633A1 (en) 2012-08-10 2014-02-12 Irras AB Fluid exchange catheter
US10786784B2 (en) 2012-09-06 2020-09-29 Smartflow Technologies, Inc. Permeate channel alterations for counter current filtration for use in cross-flow filtration modules useful in osmotic systems
US9717841B2 (en) * 2012-09-11 2017-08-01 Gary L. McNeil Closed-circuit device and methods for isolation, modification, and re-administration of specific constituents from a biological fluid source
US10159782B2 (en) 2012-09-19 2018-12-25 University Of Virginia Patent Foundation Method and system for enhanced imaging visualization of deep brain anatomy using infusion
CN102973305B (zh) 2012-11-20 2016-03-02 中国人民解放军第三军医大学第一附属医院 一种颅内出血早期血肿微创清除系统
US8721642B1 (en) 2013-01-28 2014-05-13 Neuraxis, Llc Tissue cooling clamps and related methods
WO2014160395A1 (en) 2013-03-13 2014-10-02 Beckersmith Medical, Inc. Fluid drain tube with tissue oxygenation content sensor
WO2014160469A1 (en) 2013-03-13 2014-10-02 Beckersmith Medical, Inc. Fluid drain tube with connector
WO2014160481A1 (en) 2013-03-13 2014-10-02 Beckersmith Medical, Inc. Portable automated body fluid drain control apparatus
US20140299546A1 (en) 2013-04-04 2014-10-09 Chemetics Inc. Nanofiltration process for enhanced brine recovery and sulfate removal
CN105307564A (zh) 2013-04-23 2016-02-03 桑贾伊·德豪 脑脊液冷却装置
ES2723962T3 (es) 2014-01-08 2019-09-04 A V Medical Tech Ltd Dispositivos para la toma de imágenes y el tratamiento de vasos sanguíneos
EP3094242A4 (en) 2014-01-16 2018-03-14 University Of Washington Through Its Center For Commercialization Pressure reference assemblies for body fluid drainage systems and associated methods
US10548630B2 (en) 2014-02-11 2020-02-04 Vanderbilt University System, method, and apparatus for configuration, design, and operation of an active cannula robot
CN203816046U (zh) 2014-03-25 2014-09-10 吴婷 颅内血肿穿刺引流套管
US20170209056A1 (en) 2014-04-07 2017-07-27 University Of Washington Implantable self-calibrating sensor assemblies and associated methods
CN203935243U (zh) 2014-07-03 2014-11-12 任宝龙 颅脑微创穿刺引流装置
WO2016007553A1 (en) 2014-07-08 2016-01-14 The Regents Of The University Of California Image-guided irrigating suction cannula for removal of intracerebral hemorrhage and other lesions
US10272188B1 (en) 2014-07-23 2019-04-30 Mensanan Therapeutics LLC Cerebrospinal fluid treatment
CN106714942B (zh) 2014-08-12 2020-06-23 沃特普兰尼特公司 智能流体过滤管理系统
EP3212275B1 (en) 2014-10-31 2020-08-05 Cerevasc, LLC System for treating hydrocephalus
US10258354B2 (en) 2014-12-22 2019-04-16 Cognition Medical Corp Post-conditioning suction catheter apparatus and methods
US11147540B2 (en) 2015-07-01 2021-10-19 Minnetronix, Inc. Introducer sheath and puncture tool for the introduction and placement of a catheter in tissue
ES2906952T3 (es) 2015-08-05 2022-04-21 Minnetronix Inc Sistema de filtro de flujo tangencial para la filtración de materiales a partir de fluidos biológicos
EP3842080B1 (en) * 2015-12-04 2023-04-12 Minnetronix Inc. Systems for the conditioning of cerebrospinal fluid

Patent Citations (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4904237A (en) * 1988-05-16 1990-02-27 Janese Woodrow W Apparatus for the exchange of cerebrospinal fluid and a method of treating brain and spinal cord injuries
CN1110369C (zh) * 1994-11-14 2003-06-04 宾夕法尼亚州大学信托人 用于测定和加工分析物的中尺度样品制备设备和系统
EP0921836B1 (en) * 1996-07-11 2004-05-12 Eunoe, Inc. Apparatus for treating adult-onset dementia of the alzheimer's type
US5897528A (en) * 1998-04-30 1999-04-27 Medtronic, Inc. Filtered intracerebroventricular or intraspinal access port with direct cerebrospinal fluid access
EP1600186A1 (en) * 1999-03-03 2005-11-30 UAB Research Foundation Direct central nervous system catheter and temperature control system
CN1433328A (zh) * 1999-12-03 2003-07-30 神经原治疗公司 人造脑脊液的闭合再循环的方法和设备
CN101415482A (zh) * 2006-03-31 2009-04-22 金克克国际有限公司 用于化合物分离的切向流动过滤设备、系统和方法
WO2008105959A2 (en) * 2006-10-09 2008-09-04 Neurofluidics, Inc. Cerebrospinal fluid purification system
CN101801431A (zh) * 2007-06-22 2010-08-11 循环生物制品有限责任公司 流体浓缩器和自体浓缩体液及其使用方法
US20110098623A1 (en) * 2008-06-17 2011-04-28 Georgia Tech Research Corporation Device and method of using superparamagnetic nanoparticles in treatment and removal of cells
WO2010123558A1 (en) * 2009-04-22 2010-10-28 Neurofluidics, Inc. Programmable system for conditioning of cerebrospinal fluid
US20120234694A1 (en) * 2011-01-25 2012-09-20 President And Fellows Of Harvard College Electrochemical carbon nanotube filter and method
US20150094644A1 (en) * 2013-10-01 2015-04-02 Md Start Sa Systems and methods for moving and circulating fluid to treat alzheimer's disease
US20150328295A1 (en) * 2014-05-15 2015-11-19 Washington University Vaccination against Cryptococcus
CN204352261U (zh) * 2014-12-31 2015-05-27 李思成 主要用于在脑科手术使用的改良型吸引装置

Also Published As

Publication number Publication date
AU2019283901A1 (en) 2020-01-23
AU2021218067A1 (en) 2021-09-09
AU2016304020A1 (en) 2018-02-22
JP7166915B2 (ja) 2022-11-08
CA2994669C (en) 2020-11-17
AU2019283901B2 (en) 2021-05-20
US12290785B2 (en) 2025-05-06
EP3331586A1 (en) 2018-06-13
JP6995916B2 (ja) 2022-01-17
EP3331586A4 (en) 2019-04-03
JP2018523524A (ja) 2018-08-23
EP3331586B1 (en) 2020-04-29
CN108367102A (zh) 2018-08-03
US20210077951A1 (en) 2021-03-18
AU2021218067B2 (en) 2023-03-16
WO2017023419A1 (en) 2017-02-09
US12364952B2 (en) 2025-07-22
AU2016304020B2 (en) 2019-09-19
EP3714915A1 (en) 2020-09-30
US20230120296A1 (en) 2023-04-20
ES2797223T3 (es) 2020-12-01
JP2020124526A (ja) 2020-08-20
ES2906952T3 (es) 2022-04-21
CA2994669A1 (en) 2017-02-09
US20250229230A1 (en) 2025-07-17
US20250332547A1 (en) 2025-10-30
EP3714915B1 (en) 2021-11-03

Similar Documents

Publication Publication Date Title
US11529452B2 (en) Tangential flow filter system for the filtration of materials from biologic fluids
CN108367102B (zh) 用于来自生物流体的物料的过滤的切向流过滤器系统
US10850235B2 (en) Method for filtering cerebrospinal fluid (CSF) including monitoring CSF flow
JP2020124526A5 (enExample)
JP6002136B2 (ja) 血液浄化装置
EP2231226B1 (de) Verfahren und vorrichtung zur bestimmung des transmembrandrucks bei einer extrakorporalen blutbehandlung
JP2017176847A5 (enExample)
EP2702011B1 (en) Systems and methods of controlling fouling during a filtration procedure
JP2004248844A (ja) フィルタ目詰まり状況検出方法、及びフィルタ目詰まり状況監視装置、並びにベッドサイドシステム
US10625007B2 (en) Blood purification apparatus and blood purification system
EP3646337B1 (en) A system and a method for renal replacement therapy
CN110809803B (zh) 用于肾脏替代治疗的系统和方法
CN115087473A (zh) 使用全血的血液净化器件的封闭系统循环试验装置

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant
TR01 Transfer of patent right

Effective date of registration: 20250724

Address after: American Minnesota

Patentee after: Minette ronix nerve Co.,Ltd.

Country or region after: U.S.A.

Address before: American Minnesota

Patentee before: MINNETRONIX, Inc.

Country or region before: U.S.A.

TR01 Transfer of patent right
CP03 Change of name, title or address

Address after: American Minnesota

Patentee after: Ferro Neuroscience Co.,Ltd.

Country or region after: U.S.A.

Address before: American Minnesota

Patentee before: Minette ronix nerve Co.,Ltd.

Country or region before: U.S.A.

CP03 Change of name, title or address