CN107789301A - A kind of anti-acne skin care compositions and its application - Google Patents

A kind of anti-acne skin care compositions and its application Download PDF

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Publication number
CN107789301A
CN107789301A CN201711303376.XA CN201711303376A CN107789301A CN 107789301 A CN107789301 A CN 107789301A CN 201711303376 A CN201711303376 A CN 201711303376A CN 107789301 A CN107789301 A CN 107789301A
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China
Prior art keywords
extract
skin care
parts
acne skin
acne
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Application number
CN201711303376.XA
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Chinese (zh)
Inventor
王飞
王一飞
陈海佳
葛啸虎
王小燕
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Guangzhou Saliai StemCell Science and Technology Co Ltd
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Guangzhou Saliai StemCell Science and Technology Co Ltd
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Priority to CN201711303376.XA priority Critical patent/CN107789301A/en
Publication of CN107789301A publication Critical patent/CN107789301A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/981Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

Abstract

A kind of application the invention discloses anti-acne skin care compositions and its in anti-acne skin care item are prepared, the anti-acne skin care compositions contain birds nest extract, strawflower extract, Lagotis glauca extract, coptis extract, Herba Oxalidis Corniculatae extract and poplar flower extract.The anti-acne skin care item contain the component of following weight percentage:Anti-acne skin care compositions 0.1%~5%, NMF 0.5~3%, emulsifying agent 1~2.5%, thickener 0.1~1% and deionized water surplus.The anti-acne active component of the present invention has the synergistic function of acne-removing inflammation-diminishing, hence it is evident that improves skin microenvironment, alleviates and eliminate pockmark, so as to assign the new life of skin and vigor.

Description

A kind of anti-acne skin care compositions and its application
Technical field
The present invention relates to skin care field, and in particular to a kind of anti-acne skin care compositions and its application.
Background technology
Acne also known as whelk, it is the chronic inflammatory skin of most common pilosebaceous follicle.Because of sebaceous gland duct and hair The blocking in hole, the not smooth or endocrinopathy of sebum outflow, caused by 3male hormone secretion is vigorous.From after adolescence, almost Everyone can be on the face or whelk was given birth at other positions, and simply some people's quantity are few, and the time is short, typically after 25 years old from So tend to recovery from illness, so need not be present to the mind;Somebody's quantity is more, shows as papule, blackhead, warts, abscess, tubercle, tumour, Even scar, often hinders attractive in appearance, has a strong impact on appearance, employment, social activity and marriage and childbirth of people etc..The genesis mechanism of whelk mainly with Three big factors are relevant:1) the not clear aggravation of the reason for reacting androgenic steroids, causes sebum to produce and increases;2) acne propionic acid Bacillus hyperplasia;3) capsular epithelium cell quantity increases, and has adherence, and it is excessive to form hair follicle tetention keratosis.
In order to improve the acne-removing of acne-eliminating cosmetic, researcher actively seeks various anti-acne active materials.Market at present On product for resolving poxes be primarily present problems with:1) it is big to skin irritation, easily cause allergic;2) anti-acne added is antibacterial Agent destroys the normal bacterium colony of skin;3) disabling hormone is added, causes to rely on.How the pathophysiologic features of acne-prone skin are directed to, It is the direction that researcher needs to be made great efforts to develop efficient and safe anti-acne class cosmetics.Using safe, efficiency high plant Thing extract, from keratoderma is improved, establishes effective active material Transmission system, efficiently as anti-acne active material Antibacterial and intelligent balance grease.
The content of the invention
A kind of anti-acne skin care compositions is provided it is an object of the invention to overcome the deficiencies in the prior art, dispelled with collaboration Acne anti-inflammatory, hence it is evident that improve skin microenvironment, the effect of alleviating and eliminate pockmark.
It is another object of the present invention to provide a kind of application of anti-acne skin care compositions.
It is another object of the present invention to provide a kind of anti-acne skin care item.
To achieve the above object, the technical scheme that the present invention takes is as follows:
A kind of anti-acne skin care compositions, containing birds nest extract, strawflower extract, Lagotis glauca extract, coptis extract, Herba Oxalidis Corniculatae extract and poplar flower extract.
Anti-acne active component in above-mentioned skin care compositions is birds nest extract, strawflower extract, Lagotis glauca extract, Huang Coptis extract, Herba Oxalidis Corniculatae extract and poplar flower extract, be all the extract of natural origin, it is gentle non-stimulated, do not produce according to Lai Xing, security are good;The effective inhibiting bacteria and diminishing inflammation of birds nest extract, there is the effect of releiving red swelling of the skin inflammation;Strawflower extract, rabbit Auricled Hedyotis Herb extract and coptis extract can be obviously improved skin microenvironment, inhibiting bacteria and diminishing inflammation, cure acne, alleviate and eliminate acne Trace;Herba Oxalidis Corniculatae extract and poplar flower extraction can effectively dissolve grease, dredge blockage hair follicle, inhibiting bacteria and diminishing inflammation.The present invention's dispels Acne active component has the synergistic function of acne-removing inflammation-diminishing, hence it is evident that improves skin microenvironment, alleviates and eliminate pockmark, so as to assign Give the life and vigor that skin is new.
As the preferred embodiment of anti-acne skin care compositions of the present invention, under the anti-acne skin care compositions contains State the component of parts by weight:1~4 part of birds nest extract, 2~9 parts of strawflower extract, 3~10 parts of Lagotis glauca extract, coptis extraction 0.5~4 part of 1~5 part of thing, 3~12 parts of Herba Oxalidis Corniculatae extract and poplar flower extract.
As the preferred embodiment of anti-acne skin care compositions of the present invention, under the anti-acne skin care compositions contains State the component of parts by weight:1.5~2.5 parts of birds nest extract, 3~6 parts of strawflower extract, 5~7 parts of Lagotis glauca extract, the coptis 1.5~2.5 parts of 2.5~4 parts of extract, 4~9 parts of Herba Oxalidis Corniculatae extract and poplar flower extract.
As the preferred embodiment of anti-acne skin care compositions of the present invention, under the anti-acne skin care compositions contains State the component of parts by weight:2 parts of birds nest extract, 5 parts of strawflower extract, 5.5 parts of Lagotis glauca extract, 3 parts of coptis extract, jealous woman Starch 2 parts of 8 parts of careless extract and poplar flower extract.
The present invention also provides application of the above-mentioned anti-acne skin care compositions in anti-acne skin care item are prepared.
Present invention also offers a kind of anti-acne skin care item, the component containing following weight percentage:Above-mentioned anti-acne skin care Composition 0.1~5%, NMF 0.5~3%, emulsifying agent 1~2.5%, thickener 0.1~1% and deionized water surplus.
As the preferred embodiment of anti-acne skin care item of the present invention, the NMF be Sodium Hyaluronate, glycerine, At least one of polyglutamic acid sodium, algal polysaccharides, sorbierite.
As the preferred embodiment of anti-acne skin care item of the present invention, the emulsifying agent is beeswax, polyoxyethylene sheep At least one of hair fat, polyoxyethylene lanonol, Tween-80.
As the preferred embodiment of anti-acne skin care item of the present invention, the thickener is carragheen, carbomer, fruit At least one of glue, cellulose.
Present invention also offers the preparation method of above-mentioned anti-acne skin care item, comprise the following steps:
1) each component raw material is weighed in proportion;
2) NMF, emulsifying agent, thickener and deionized water are stirred in 65~80 DEG C of rotating speeds with 800~2000rpm Uniformly, mixture is obtained;
3) mixture for obtaining step 2) is cooled to 45~50 DEG C, adds above-mentioned anti-acne skin care compositions, with 1000~ 1500rpm rotating speed is well mixed, and obtains described anti-acne skin care item.
Prior art is compared, the invention has the advantages that:
The anti-acne active component of the present invention is the extract of natural origin, gentle non-stimulated, does not produce dependence, security It is good;The effective inhibiting bacteria and diminishing inflammation of birds nest extract, there is the effect of releiving red swelling of the skin inflammation;Strawflower extract, Lagotis glauca extract Skin microenvironment can be obviously improved with coptis extract, inhibiting bacteria and diminishing inflammation, cures acne, alleviates and eliminates pockmark;Creeping oxalis carries Thing and poplar flower extraction is taken effectively to dissolve grease, dredge blockage hair follicle, inhibiting bacteria and diminishing inflammation.The anti-acne active component tool of the present invention There is the synergistic function of acne-removing inflammation-diminishing, hence it is evident that improve skin microenvironment, alleviate and eliminate pockmark, so as to assign skin new life Machine and vigor.
Embodiment
For the object, technical solutions and advantages of the present invention are better described, below in conjunction with specific embodiment to the present invention Further illustrate.It will be appreciated by those skilled in the art that specific embodiment described herein is only to explain the present invention, not For limiting the present invention.
Test method used in following embodiments is conventional method unless otherwise specified;Institute in following embodiments The material that uses, reagent etc., unless otherwise specified, are commercially obtained.
Birds nest extract, strawflower extract, Lagotis glauca extract, coptis extract, Herba Oxalidis Corniculatae extract and poplar flower carry Thing is taken to be purchased from Xi'an You Shuo bio tech ltd.
Embodiment 1
A kind of embodiment of anti-acne skin care compositions of the present invention, anti-acne skin care compositions contains following heavy described in the present embodiment Measure the component of part:2 parts of birds nest extract, 5 parts of strawflower extract, 5.5 parts of Lagotis glauca extract, 3 parts of coptis extract, creeping oxalis 2 parts of 8 parts of extract and poplar flower extract.
Embodiment 2
A kind of embodiment of anti-acne skin care compositions of the present invention, anti-acne skin care compositions contains following heavy described in the present embodiment Measure the component of part:1.5 parts of birds nest extract, 3 parts of strawflower extract, 7 parts of Lagotis glauca extract, 4 parts of coptis extract, creeping oxalis 1.5 parts of 4 parts of extract and poplar flower extract.
Embodiment 3
A kind of embodiment of anti-acne skin care compositions of the present invention, anti-acne skin care compositions contains following heavy described in the present embodiment Measure the component of part:2.5 parts of birds nest extract, 6 parts of strawflower extract, 5 parts of Lagotis glauca extract, 2.5 parts of coptis extract, jealous woman slurry 2.5 parts of 9 parts of careless extract and poplar flower extract.
Embodiment 4
A kind of embodiment of anti-acne skin care compositions of the present invention, anti-acne skin care compositions contains following heavy described in the present embodiment Measure the component of part:1 part of birds nest extract, 9 parts of strawflower extract, 3 parts of Lagotis glauca extract, 5 parts of coptis extract, creeping oxalis carry Take 4 parts of 3 parts of thing and poplar flower extract.
Embodiment 5
A kind of embodiment of anti-acne skin care compositions of the present invention, anti-acne skin care compositions contains following heavy described in the present embodiment Measure the component of part:4 parts of birds nest extract, 2 parts of strawflower extract, 10 parts of Lagotis glauca extract, 1 part of coptis extract, creeping oxalis 0.5 part of 12 parts of extract and poplar flower extract.
Embodiment 6
A kind of embodiment of anti-acne skin care item of the present invention, anti-acne skin care item contain following weight percentage described in the present embodiment Component:Anti-acne skin care compositions 3%, Sodium Hyaluronate 0.5%, Tween-80 2.5%, the and of carragheen 0.1% of embodiment 1 Deionized water surplus.
The anti-acne skin care item preparation method of the present embodiment is:
1) each component raw material is weighed in proportion;
2) Sodium Hyaluronate, Tween-80, carragheen and deionized water are stirred at 70 DEG C with 1500rpm rotating speed, Obtain mixture;
3) mixture for obtaining step 2) is cooled to 45 DEG C, adds the anti-acne skin care compositions of embodiment 1, with 1200rpm rotating speed is well mixed, and obtains described anti-acne skin care item.
Embodiment 7
A kind of embodiment of anti-acne skin care item of the present invention, anti-acne skin care item contain following weight percentage described in the present embodiment Component:The anti-acne skin care compositions 5% of embodiment 2, glycerine 0.5%, polyglutamic acid sodium 0.5%, algal polysaccharides 2%, beeswax 0.5%th, polyoxyethylene lanonol 0.5%, pectin 0.5%, cellulose 0.5% and deionized water surplus.
The anti-acne skin care item preparation method of the present embodiment is:
1) each component raw material is weighed in proportion;
2) by glycerine, polyglutamic acid sodium, algal polysaccharides, beeswax, polyoxyethylene lanonol, pectin, fiber and deionized water Stirred at 80 DEG C with 2000rpm rotating speed, obtain mixture;
3) mixture for obtaining step 2) is cooled to 50 DEG C, adds the anti-acne skin care compositions of embodiment 2, with 1000rpm rotating speed is well mixed, and obtains described anti-acne skin care item.
Embodiment 8
A kind of embodiment of anti-acne skin care item of the present invention, anti-acne skin care item contain following weight percentage described in the present embodiment Component:Anti-acne skin care compositions 0.1%, sorbierite 2%, algal polysaccharides 0.5%, the Wool wax alcohols,ethoxylated of embodiment 4 2%th, carbomer 0.5% and deionized water surplus.
The anti-acne skin care item preparation method of the present embodiment is:
1) each component raw material is weighed in proportion;
2) sorbierite, algal polysaccharides, Wool wax alcohols,ethoxylated, carbomer and deionized water are turned at 65 DEG C with 800rpm Speed stirs, and obtains mixture;
3) mixture for obtaining step 2) is cooled to 50 DEG C, adds the anti-acne skin care compositions of embodiment 4, with 1500rpm rotating speed is well mixed, and obtains described anti-acne skin care item.
Comparative example 1
Anti-acne skin care compositions contains following components in parts by weight:3 parts of birds nest extract, 11 parts of strawflower extract, rabbit ear Careless 11.5 parts of extract.
Comparative example 2
Anti-acne skin care compositions contains following components in parts by weight:5.5 parts of Lagotis glauca extract, 6 parts of coptis extract, jealous woman Starch 4 parts of 10 parts of careless extract and poplar flower extract.
Comparative example 3
This comparative example anti-acne skin care item contain the component of following weight percentage:The anti-acne skin care compositions of comparative example 1 3%th, Sodium Hyaluronate 0.5%, Tween-80 2.5%, carragheen 0.1% and deionized water surplus.
The anti-acne skin care item preparation method of this comparative example is:
1) each component raw material is weighed in proportion;
2) Sodium Hyaluronate, Tween-80, carragheen and deionized water are stirred at 70 DEG C with 1500rpm rotating speed, Obtain mixture;
3) mixture for obtaining step 2) is cooled to 45 DEG C, adds the anti-acne skin care compositions of embodiment 1, with 1200rpm rotating speed is well mixed, and obtains described anti-acne skin care item.
Comparative example 4
Anti-acne skin care item contain the component of following weight percentage described in this comparative example:The anti-acne skincare composition of comparative example 2 Thing 3%, Sodium Hyaluronate 0.5%, Tween-80 2.5%, carragheen 0.1% and deionized water surplus.
The anti-acne skin care item preparation method of this comparative example is:
1) each component raw material is weighed in proportion;
2) Sodium Hyaluronate, Tween-80, carragheen and deionized water are stirred at 70 DEG C with 1500rpm rotating speed, Obtain mixture;
3) mixture for obtaining step 2) is cooled to 45 DEG C, adds the anti-acne skin care compositions of embodiment 1, with 1200rpm rotating speed is well mixed, and obtains described anti-acne skin care item.
Skin care item effect determines
(1) antibacterial experiment in vitro
The anti-acne skin care compositions of embodiment 1, embodiment 2, embodiment 4 and comparative example 1~2 is prepared as concentration and is The 50mg/mL aqueous solution, blank control group is set.Bacteriostatic activity uses agar diffusion method, is fallen in a diameter of 9cm culture dish Enter 10mL or so sterile letheen solution, Oxford cup is being placed above after solidification, is being added after culture medium cooling with every 100mL culture mediums Enter 2mL bacteria suspension, shake up and pour into rapidly in the culture dish for laying Oxford cup afterwards, 150 μ L skin care item solution, knot are added per hole Fruit is as shown in table 1.
Table 1
It can be seen that the anti-acne skin care compositions of embodiment preparation to salmonella, golden yellow grape bacillus by the result of table 1 There is obvious inhibitory action with Escherichia coli, and fungistatic effect is substantially better than the anti-acne skin care compositions of comparative example 1~2, table Anti-acne skin care compositions prepared by the bright present invention has preferably collaboration fungistatic effect.
(2) anti-acne anti-inflammatory is tested
100 16~25 years old volunteers for suffering from whelk are chosen, are divided into 5 groups, experimental group is the embodiment of the present invention 6,7,8 The anti-acne skin care item of preparation, control group are the anti-acne skin care item of comparative example 3~4.Skin care is uniformly smeared after the daily face cleaning of volunteer Product twice, observe change of skin, as a result as shown in table 2 after 30 days.
Slip=(using the rear inflammation skin damage number of proinflammatory skin damage number-use) × 100%/uses proinflammatory skin Damage number;
It is almost recovered:Inflammation skin damages number slip >=90%;
It is effective:Inflammation skin damage number slip 60%~90%;
Take a turn for the better:Inflammation skin damage number slip 20%~60%;
It is invalid:Inflammation skin damages number slip<20% or aggravate.
Efficient=(it is almost recovered+effective+take a turn for the better) × 100%/number of cases
Table 2
As seen from the results in Table 2, the anti-acne anti-inflammatory of anti-acne skin care item prepared by the embodiment of the present invention 6~8 is efficient obvious high In comparative example 3~4, show anti-acne active component birds nest extract of the invention, strawflower extract, Lagotis glauca extract, the coptis Extract, Herba Oxalidis Corniculatae extract and poplar flower extract have the synergistic function of acne-removing inflammation-diminishing, hence it is evident that improve skin micro-loop Border, alleviate and eliminate pockmark, so as to assign the new life of skin and vigor.
(3) human body skin adverse reaction is tested
The volunteer 90 that the age is 16~25 years old is chosen, is randomly divided into 3 groups, every group of each 30 people.Reference《Cosmetics health Specification》The related request of " human skin patch " carries out human body skin adverse reaction experiment in (2007 editions).Respectively will Anti-acne skin care item prepared by 0.025g embodiment 6~8 are added on spot examination device, and spot examination device is attached into will with non-stimulated adhesive tape The forearm song side of hope person, is gently pressed with hand and is allowed to uniformly be attached on skin, except despeckle examination device after 24h, respectively in 30min, 1h, Dermoreaction is observed after 2h, 24h, and according to table 3《Skin adverse reaction grade scale table》Record reaction result.
Table 3
Table 4
Grading system Number of cases Ratio
0 30 100%
1 0 0
2 0 0
3 0 0
4 0 0
Table 4 is the skin adverse reaction result of anti-acne skin care item prepared by embodiment 6.Anti-acne prepared by embodiment 7~8 The skin adverse reaction result of skin care item is same as Example 6.Result of the test shows that the volunteer of the embodiment of the present invention 6~8 tries It is feminine gender to test result, is occurred without bad dermoreaction, shows that anti-acne skin care item prepared by the present invention are gently non-stimulated, security It is good.
Result above shows that it is micro- to be obviously improved skin in anti-acne skin care compositions and anti-acne skin care item of the invention Environment, inhibiting bacteria and diminishing inflammation, acne is cured, alleviate and eliminate pockmark, shine the new life of skin and vigor.
Finally, it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention rather than the present invention is protected The limitation of scope is protected, although being explained in detail with reference to preferred embodiment to the present invention, one of ordinary skill in the art should Understand, technical scheme can be modified or equivalent substitution, without departing from the essence of technical solution of the present invention And scope.

Claims (10)

1. a kind of anti-acne skin care compositions, it is characterised in that the anti-acne skin care compositions contains birds nest extract, strawflower extraction Thing, Lagotis glauca extract, coptis extract, Herba Oxalidis Corniculatae extract and poplar flower extract.
2. anti-acne skin care compositions according to claim 1, it is characterised in that the anti-acne skin care compositions contains following The component of parts by weight:1~4 part of birds nest extract, 2~9 parts of strawflower extract, 3~10 parts of Lagotis glauca extract, coptis extract 0.5~4 part of 1~5 part, 3~12 parts of Herba Oxalidis Corniculatae extract and poplar flower extract.
3. anti-acne skin care compositions according to claim 1, it is characterised in that the anti-acne skin care compositions contains following The component of parts by weight:1.5~2.5 parts of birds nest extract, 3~6 parts of strawflower extract, 5~7 parts of Lagotis glauca extract, the coptis carry Take 1.5~2.5 parts of 2.5~4 parts of thing, 4~9 parts of Herba Oxalidis Corniculatae extract and poplar flower extract.
4. anti-acne skin care compositions according to claim 1, it is characterised in that the anti-acne skin care compositions contains following The component of parts by weight:2 parts of birds nest extract, 5 parts of strawflower extract, 5.5 parts of Lagotis glauca extract, 3 parts of coptis extract, jealous woman slurry 2 parts of 8 parts of careless extract and poplar flower extract.
5. application of the anti-acne skin care compositions in anti-acne skin care item are prepared as described in any one of Claims 1 to 4.
A kind of 6. anti-acne skin care item, it is characterised in that the component containing following weight percentage:Any one of Claims 1 to 4 institute The anti-acne skin care compositions 0.1~5% stated, NMF 0.5~3%, emulsifying agent 1~2.5%, thickener 0.1~1% and go from Sub- water surplus.
7. anti-acne skin care item according to claim 6, it is characterised in that the NMF is Sodium Hyaluronate, glycerine, gathered At least one of sodium glutamate, algal polysaccharides, sorbierite.
8. anti-acne skin care item according to claim 6, it is characterised in that the emulsifying agent is beeswax, polyoxyethylene wool At least one of fat, polyoxyethylene lanonol, Tween-80.
9. anti-acne skin care item according to claim 6, it is characterised in that the thickener is carragheen, carbomer, fruit At least one of glue, cellulose.
10. the preparation method of anti-acne skin care item according to claim 6, it is characterised in that comprise the following steps:
1) each component raw material is weighed in proportion;
2) NMF, emulsifying agent, thickener and deionized water are stirred at 65~80 DEG C with 800~2000rpm rotating speed, Obtain mixture;
3) mixture for obtaining step 2) is cooled to 45~50 DEG C, anti-acne skin care compositions is added, with 1000~1500rpm's Rotating speed is well mixed, and obtains described anti-acne skin care item.
CN201711303376.XA 2017-12-06 2017-12-06 A kind of anti-acne skin care compositions and its application Withdrawn CN107789301A (en)

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CN109276499A (en) * 2018-11-14 2019-01-29 浙江海洋大学 A kind of the natural plants hand cleanser and preparation method of preservative free
CN111450036A (en) * 2020-05-09 2020-07-28 四川万物本草健康科技有限公司 Product composition containing houttuynia cordata and application of product composition in skin care products
CN114085294A (en) * 2021-11-18 2022-02-25 青岛农业大学 Structure representation and activity research method of Tibetan coptis polysaccharide selenium nanoparticles
CN115054549A (en) * 2022-06-30 2022-09-16 两面针(江苏)实业有限公司 Oil-controlling and bacteriostatic coptis shampoo

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109276499A (en) * 2018-11-14 2019-01-29 浙江海洋大学 A kind of the natural plants hand cleanser and preparation method of preservative free
CN111450036A (en) * 2020-05-09 2020-07-28 四川万物本草健康科技有限公司 Product composition containing houttuynia cordata and application of product composition in skin care products
CN114085294A (en) * 2021-11-18 2022-02-25 青岛农业大学 Structure representation and activity research method of Tibetan coptis polysaccharide selenium nanoparticles
CN114085294B (en) * 2021-11-18 2022-10-14 青岛农业大学 Structure representation and activity research method of Tibetan coptis polysaccharide selenium nanoparticles
CN115054549A (en) * 2022-06-30 2022-09-16 两面针(江苏)实业有限公司 Oil-controlling and bacteriostatic coptis shampoo
CN115054549B (en) * 2022-06-30 2023-07-28 两面针(江苏)实业有限公司 Oil-control and antibacterial coptis chinensis shampoo

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Application publication date: 20180313