CN104434740A - Traditional Chinese medicine gel for removing acnes and preparation method of traditional Chinese medicine gel - Google Patents
Traditional Chinese medicine gel for removing acnes and preparation method of traditional Chinese medicine gel Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine gel for removing acnes and a preparation method of the traditional Chinese medicine gel. The traditional Chinese medicine gel for removing acnes comprises the following substances: a burdock extract liquid, a pine needle extract liquid, a mother chrysanthemum extract liquid, an aubergine root extract liquid, royal jelly, a honeysuckle extract liquid, sodium carboxymethylcellulose, sodium alginate tech grade, a cross-linked polymer QM of polyvinylmethyl ether/methyl acrylate and decadiene, glycerinum, essence, ethylparaben, distilled water and 1,2-propylene glycol. The traditional Chinese medicine gel for removing acnes prepared by the method is faint yellow, glittering and translucent, transparent, appropriate in viscosity and thickness, good in stability, and fresh and pleasant in smell; the skin is fine, rosy and glossy after the traditional Chinese medicine gel is used; the acnes and acne marks can be removed; and the traditional Chinese medicine gel has the effects of removing the acnes and protecting the skin.
Description
Technical field
The present invention relates to a kind of anti-acne skin care item and preparation method thereof, particularly relate to a kind of Chinese medicine blemish clearing gel agent and preparation method thereof, belong to household chemicals field.
Background technology
Acne (having another name called small pox) is a kind of chronic hair follicle sebum gland disease, is one of modal dermatosis of department of dermatologry.Its morbidity mainly raises fast with Serum Testosterone Levels, hypersteatosis, propionibacterium acnes bacterium breed in a large number, the abnormal factor such as (blocking) and inflammatory reaction of the keratinization of pilosebaceous duct is relevant.Mainly betide the position that the sebum secretion such as face, chest and back is vigorous.Because acne is easily sent out in adolescence, so be otherwise known as " comedo ".Often can naturally retreat or fully recover after adolescence, but also have generation in crowd more than 30 years old.Although acne is the tendency with spontaneous recovery, but acne itself and acne treatment not in time or the malpractice cicatrix, the pox hole that cause can have a strong impact on quality of life of patient, cause patient to subject immense pressure in spirit, and even become certain financial burden.
The method of current Acne treatment is mainly divided into chemotherapy and naturopathy, (skin irritation is larger mainly with tretinoin for its drug treatment, restricted application, side effect is more), antibiotics (selectivity is poor, and the course for the treatment of is longer, and thalline easily produces resistance), (dosage is wayward for hormones, safety is poor) etc. be main component, but therapeutic effect is not satisfactory, easy scar, more importantly the suitability of medicine to allergic skin of some Acne treatments is poor.Naturopathy is also because operating the reasons such as compliance that is complicated, expensive, patient is poor and being difficult to popularize.
Summary of the invention
For the shortcoming of above-mentioned prior art, the invention provides kind Chinese medicine blemish clearing gel agent and preparation method thereof, overcome, side effect more, easy allergy comparatively large to skin irritation,
A unsafe difficult problem, has removing dampness to relieve itching, clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, detumescence and promoting granulation, conditioning and protection face skin simultaneously, promotes effect of cell metabolism, slow down aging, and can not produce drug dependence.
To achieve these goals, the invention provides the agent of a kind of Chinese medicine blemish clearing gel, it is characterized in that, containing following material and content thereof in the agent of described Chinese medicine blemish clearing gel:
Fructus Arctii extracting solution 0.5-5ml
Pine needle extract 0.5-5ml
Flos Chrysanthemi Indici extracting solution 0.5-5ml
Root extracting solution 0.5-5ml
Flos Lonicerae extractive solution 0.5-5ml
Royal jelly solution 0.5-5ml
Sodium carboxymethyl cellulose 0.01-1.5g
Sodium alginate 0.01-1g
The cross linked polymer QM 0.01-1g of polyvinyl methyl ethermaleic anhydride/acrylic acid methyl ester. and decadinene
Glycerol 1-6ml
1,2-PD 1-6ml
Essence 0.01-0.05g
75% ethyl hydroxybenzoate alcoholic solution 0.01-1.5g
Distilled water 21-35ml.
Can add essence according to different demands, described essence can be one or more in rose essence, peach flavor, flavoring pineapple essence, Fructus Citri Limoniae essence, green cucumber essence, jasmin essence, osmanthus flower fragrance.
Described Chinese medicine blemish clearing gel agent preparation method, comprises the steps:
Step one: get sodium carboxymethyl cellulose powder 0.01-1.5g, add 10-20ml distilled water, stirs, fully dissolves to obtain carboxymethylcellulose sodium solution;
Step 2: get sodium alginate powder 0.01-1g, adds 5-16ml distilled water, stirs, fully dissolves to obtain sodium alginate soln;
Step 3: get QM powder 0.01-1g, add 1-10ml distilled water, stirs, fully dissolves to obtain QM solution;
Step 4: by above-mentioned three kinds of solution mixing, fully stirs to obtain clear, gel substrate that viscosity is good;
Step 5: get Fructus Arctii extracting solution 0.5-5ml, pine needle extract 0.5-5ml, Flos Chrysanthemi Indici extracting solution 0.5-5ml, Flos Chrysanthemi Indici get liquid 0.5-5ml, royal jelly solution 0.5-5ml, Flos Lonicerae extractive solution 0.5-5ml, glycerol 1-6ml, 1,2-propylene glycol 1-6ml, essence 0.01-0.05g, 75% ethyl hydroxybenzoate alcoholic solution 0.01-1.5g, add in above-mentioned prepared gel-type vehicle successively, stir, make mix homogeneously, obtain the agent of Chinese medicine blemish clearing gel.
Described Fructus Arctii extracting solution is prepared by the following method: get fresh burdock root and thinly slice, and heating decocts extracts, and Extracting temperature is 80-100 DEG C, extracts 3 times, adds the water of 10-16 times amount for the 1st time, extracts 0.5-2h; Add the water of 8-15 times amount for 2nd time, extract 0.5-2h; Add the water of 6-10 times amount for 3rd time, extract 0.5-2h; Each use three layers of filtered through gauze, merging filtrate, concentrates filtrate to 1-5 times of g/ml of Radix Arctii weight, obtains Fructus Arctii extracting solution.
Described pine needle extract is prepared by the following method: get fresh needles, reflux, extract, 3 times, adds the water of 10-15 times amount for the 1st time, extracts 0.5-2h; Add 8-12 times of water 2nd time, extract 0.5-2h; Add 6-10 times of water 3rd time, extract 0.5-2h; Each three layers of filtered through gauze, merging filtrate, concentrates filtrate to 1-5 times of g/ml of Folium Pini weight, obtains pine needle extract.
Described Flos Chrysanthemi Indici extracting solution is prepared by the following method: get dry Flos Chrysanthemi Indici, reflux, extract, 3 times, adds 10-20 times amount 60% ethanol the 1st time, soaks 20-60min, extracts 0.5-2h; Add 8-18 doubly 60% ethanol for 2nd time, extract 0.5-2h; Add 6-12 doubly 60% ethanol for 3rd time, extract 0.5-2h; Each three layers of filtered through gauze, merging filtrate, concentrates filtrate to 1-5 times of g/ml of Flos Chrysanthemi Indici weight, obtains Flos Chrysanthemi Indici extracting solution.
Described Flos Lonicerae extractive solution is prepared by the following method: extracting honeysuckle dry flower, reflux, extract, 3 times, adds 65% ethanol of 10-18 times amount for the 1st time, extracts 0.5-2h; Add 8-15 doubly 60% ethanol for 2nd time, extract 0.5-2h; Add 6-10 doubly 60% ethanol for 3rd time, extract 0.5-2h; Each three layers of filtered through gauze, merging filtrate, concentrates filtrate to 1-5 times of g/ml of Flos Lonicerae weight, obtains Flos Lonicerae extractive solution.
Described Radix Solani Melongenae extracting solution is prepared by the following method: get Radix Solani Melongenae, be ground into coarse powder, and heating decocts extracts, and Extracting temperature is 80-100 DEG C, extracts 3 times, adds the water of 10-15 times amount for the 1st time, extracts 0.5-2h; Add the water of 8-12 times amount for 2nd time, extract 0.5-2h; Add the water of 6-10 times amount for 3rd time, extract 0.5-2h; Each use three layers of filtered through gauze, merging filtrate, concentrates filtrate to 1-5 times of g/ml of Radix Arctii weight, obtains Radix Solani Melongenae extracting solution.
Described royal jelly solution is prepared by the following method: royal jelly extracting lyophilized powder, adds the water of 50-100 times amount, and stir to obtain royal jelly solution.
Various composition of the present invention is as follows:
Fresh burdock root contains the compositions such as inulin, polyacetylene class, several amino acids, polyphenol, organic acid and aldehydes.Polyacetylene class material in Radix Arctii can play well antibacterial and antifungal effect, chlorogenic acid has anti-allergic effects, also can have certain inhibitory action to escherichia coli, bacillus subtilis, staphylococcus glucose bacterium and micrococcus luteus when its concentration reaches finite concentration.Fructus Arctii can clear up blood rubbish, impels the metabolism of cells in vivo, prevents aging, makes skin beauty careful, thus is beneficial to the reparation of small pox skin and reduces the generation of small pox.The traditional Chinese medical science thinks that Radix Arctii has the effects such as lung qi dispersing rash, can be used for measles, rubella etc.
Folium Pini contains the compositions such as volatile oil, flavonoid, resin, cellulose, lignin, chlorophyll, carotene, vitamin, trace element.Pine Needle Essential Oil class has the effects such as wind dispelling, anthelmintic, antibacterial, antiviral.The keratinization that extract from pine needles can correct pilosebaceous duct is abnormal, has the effect of anti-acne.
Flos Chrysanthemi Indici has the effect clearing away the dampness and heat, remove toxin, reducing swelling and alleviating pain, all has inhibitory action to staphylococcus aureus, diphtheria corynebacterium, streptococcus, bacillus pyocyaneus, dysentery bacterium, influenza virus.
Flos Lonicerae is the good medicine of dispelling wind-heat, heat-clearing and toxic substances removing, for various febrile disease, as fever of the body, dermexanthesis, sends out the diseases such as speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain.
Radix Solani Melongenae has effect of loose blood, detumescence, has antibacterial, treating chilblain, controls the effect of migratory arthralgia and skin pruritus.
Lac regis apis is containing protein, sugar, fatty acid, vitamin, enzyme, hormone, free amino acid and trace element etc.Protein and fatty acid are the main bioactive ingredients of Lac regis apis.Lac regis apis or royal jelly lyophilized powder have antiinflammatory and promote the effect such as skin wound healing and Promote cell's growth.Anti-oxidation efficacy is the effect that Lac regis apis is generally affirmed by masses, and it has very strong effect to the reparation of cell and regeneration.In addition the functions such as radiation-resistant are also had.
QM is that (abbreviation of the cross linked polymer of polyvinyl methyl ethermaleic anhydride/acrylic acid methyl ester. and decadinene is new gang's thickening agent, can makes emulsion-stabilizing, thickening, give fabulous skinfeel, almost imperceptible viscosity PVM/MA decadiene crosslinked polymer.
Glycerol is a kind of non-irritating and the natural plants wetting agent locking moisture, can be used as the softening agent of personal care product, moisturizing agent and emollient.The glycerol that purity is higher is watered rear use, and moisturizing effect is very good, with rear soft skin, touches up very comfortable.
Beneficial effect: in Chinese medicine blemish clearing gel of the present invention agent, Radix Arctii has well antibacterial, antifungal and anti-allergic effects, kill the antibacterial and fungus that cause acne to occur or suppress it to breed, and metal ion is had to the ability of good absorbability and removing, thus make skin more healthy.Folium Pini has antibacterial, antiviral function and energy blood circulation promoting, improves the function of blood capillary, thus the keratinization can correcting pilosebaceous duct is abnormal, makes the more remarkable effect of anti-acne; Flos Chrysanthemi Indici has the effect clearing away the dampness and heat, remove toxin, reducing swelling and alleviating pain; Flos Lonicerae has clearing away heat and cooling blood, effect of toxin expelling sore; Radix Solani Melongenae has effect of anti-bacterial, anti-itching; Lac regis apis has the effects such as antiinflammatory, radioprotective, antioxidation, promotion skin wound healing and Promote cell's growth; Glycerol has the effect of good moisturizing.
Adopt the blemish clearing gel agent that in said extracted liquid and cosmetics, common carrier is made, non-stimulated to skin gentleness, have no side effect, toxin expelling sore, removing dampness to relieve itching, clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, detumescence and promoting granulation, repair small pox flesh and reach comprehensive acne-removal function.Due to raw materials used be pure Chinese medicine not containing antibiotic and hormone, can not drug dependence be produced.Effectively can secrete in a large number sebaceous gland, propionibacterium acnes increment, the keratinization exception of pilosebaceous duct and inflammation etc. cause the factor of acne to provide comprehensive treatment, and focus on the reparation of small pox flesh and the maintenance of skin, thus do not stay cicatrix, without recurrence, to secure good health, beautiful, careful skin.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1
The agent of the present embodiment Chinese medicine blemish clearing gel obtains as follows:
Step one: take sodium carboxymethyl cellulose powder 0.09g, add 15ml distilled water, stirs, fully dissolves to obtain carboxymethylcellulose sodium solution;
Step 2: take sodium alginate powder 0.08g, adds 8ml distilled water, stirs, fully dissolves to obtain sodium alginate soln;
Step 3: take QM powder 0.08g, add 5ml distilled water, stirs, fully dissolves to obtain QM solution;
Step 4: by above-mentioned three kinds of solution mixing, fully stirs to obtain clear, gel substrate that viscosity is good;
Step 5: get above-mentioned Fructus Arctii extracting solution 1ml, pine needle extract 1 ml, Flos Chrysanthemi Indici extracting solution 1 ml, Radix Solani Melongenae extracting solution 1ml, royal jelly solution 1.5ml, Flos Lonicerae extractive solution 1.5ml, glycerol 3ml, 1,2-propylene glycol 3ml, essence 0.02g, 75% ethyl hydroxybenzoate alcoholic solution 0.05g, add in above-mentioned prepared gel-type vehicle successively, stir, make mix homogeneously, obtain the agent of Chinese medicine blemish clearing gel.Described essence can be one or more in rose essence, peach flavor, flavoring pineapple essence, Fructus Citri Limoniae essence, green cucumber essence, jasmin essence, osmanthus flower fragrance.
The wherein preparation of Fructus Arctii extracting solution: get fresh burdock root 100g, thinly slice, heating decocts extracts, and Extracting temperature is 100 DEG C, extracts 3 times, adds the water of 12 times amount for the 1st time, extracts 1.5h; Add the water of 10 times amount for 2nd time, extract 1h; Add the water of 10 times amount for 3rd time, extract 1h; Each use three layers of filtered through gauze, merging filtrate, concentrates filtrate to 3 times of g/ml of Radix Arctii weight, obtains Fructus Arctii extracting solution.
The wherein preparation of pine needle extract: take 50g fresh needles, reflux, extract, 3 times, adds the water of 13 times amount for the 1st time, extracts 1h; Add 11 times of water 2nd time, extract 1h; Add 10 times of water 3rd time, extract 1h; Each three layers of filtered through gauze, merging filtrate, concentrates filtrate to 3 times of g/ml of Folium Pini weight, obtains pine needle extract.
The wherein preparation of Flos Chrysanthemi Indici extracting solution: take dry Flos Chrysanthemi Indici 40g, reflux, extract, 3 times, adds 18 times amount 60% ethanol for the 1st time, soaks 30min, extracts 1.5h; Add 15 times of 60% ethanol 2nd time, extract 1.5h; Add 10 times of 60% ethanol 3rd time, extract 1h; Each three layers of filtered through gauze, merging filtrate, concentrates filtrate to 3 times of g/ml of Flos Chrysanthemi Indici weight, obtains Flos Chrysanthemi Indici extracting solution.
The wherein preparation of Flos Lonicerae extractive solution: take Flos Lonicerae dry flower 40g, reflux, extract, 3 times, adds 65% ethanol of 17 times amount for the 1st time, extracts 1.5h; Add 12 times of 60% ethanol 2nd time, extract 1.5h; Add 10 times of 60% ethanol 3rd time, extract 1h; Each three layers of filtered through gauze, merging filtrate, concentrates filtrate to 2 times of g/ml of Flos Lonicerae weight, obtains Flos Lonicerae extractive solution.
The wherein preparation of Radix Solani Melongenae extracting solution: get Radix Solani Melongenae appropriate, be ground into coarse powder, take coarse powder 100g, heating decocts extracts, and Extracting temperature is 100 DEG C, extracts 3 times, adds the water of 14 times amount for the 1st time, extracts 1.5h; Add the water of 11 times amount for 2nd time, extract 1.5h; Add the water of 10 times amount for 3rd time, extract 1h; Each use three layers of filtered through gauze, merging filtrate, concentrates filtrate to 2 times of g/ml of Radix Arctii weight, obtains Radix Solani Melongenae extracting solution.
The wherein preparation of royal jelly solution: royal jelly extracting lyophilized powder 0.5g, adds the water of 25ml, stir to obtain royal jelly solution.
Embodiment 2
The agent of the present embodiment Chinese medicine blemish clearing gel obtains as follows:
Step one: take sodium carboxymethyl cellulose powder 0.15g, add 20ml distilled water, stirs, fully dissolves to obtain carboxymethylcellulose sodium solution;
Step 2: take sodium alginate powder 0.2g, adds 12ml distilled water, stirs, fully dissolves to obtain sodium alginate soln;
Step 3: take QM powder 0.15g, add 10ml distilled water, stirs, fully dissolves to obtain QM solution;
Step 4: by above-mentioned three kinds of solution mixing, fully stirs to obtain clear, gel substrate that viscosity is good;
Step 5: get above-mentioned Fructus Arctii extracting solution 3ml, pine needle extract 3ml, Flos Chrysanthemi Indici extracting solution 3ml, Radix Solani Melongenae extracting solution 3ml, royal jelly solution 3ml, Flos Lonicerae extractive solution 3ml, glycerol 3ml, 1,2-propylene glycol 3ml, essence 0.02g, 75% ethyl hydroxybenzoate alcoholic solution 0.5g, add in above-mentioned prepared gel-type vehicle successively, stir, make mix homogeneously, obtain the agent of Chinese medicine blemish clearing gel.Described essence can be one or more in rose essence, peach flavor, flavoring pineapple essence, Fructus Citri Limoniae essence, green cucumber essence, jasmin essence, osmanthus flower fragrance.
The wherein preparation of Fructus Arctii extracting solution: get fresh burdock root 100g, thinly slice, heating decocts extracts, and Extracting temperature is 100 DEG C, extracts 3 times, adds the water of 14 times amount for the 1st time, extracts 1.5h; Add the water of 10 times amount for 2nd time, extract 1h; Add the water of 10 times amount for 3rd time, extract 0.5h; Each use three layers of filtered through gauze, merging filtrate, concentrates filtrate to 2 times of g/ml of Radix Arctii weight, obtains Fructus Arctii extracting solution.
The wherein preparation of pine needle extract: take fresh needles 30g, reflux, extract, 3 times, adds the water of 11 times amount for the 1st time, extracts 1h; Add 10 times of water 2nd time, extract 1h; Add 8 times of water 3rd time, extract 1h; Each three layers of filtered through gauze, merging filtrate, concentrates filtrate to 4 times of g/ml of Folium Pini weight, obtains pine needle extract.
The wherein preparation of Flos Chrysanthemi Indici extracting solution: take dry Flos Chrysanthemi Indici 40g, reflux, extract, 3 times, adds 18 times amount 60% ethanol for the 1st time, soaks 30min, extracts 1h; Add 15 times of 60% ethanol 2nd time, extract 1h; Add 10 times of 60% ethanol 3rd time, extract 1h; Each three layers of filtered through gauze, merging filtrate, concentrates filtrate to 4 times of g/ml of Flos Chrysanthemi Indici weight, obtains Flos Chrysanthemi Indici extracting solution.
The wherein preparation of Flos Lonicerae extractive solution: take Flos Lonicerae dry flower 50g, reflux, extract, 3 times, adds 65% ethanol of 15 times amount for the 1st time, extracts 1h; Add 12 times of 60% ethanol 2nd time, extract 1h; Add 8 times of 60% ethanol 3rd time, extract 0.5h; Each three layers of filtered through gauze, merging filtrate, concentrates filtrate to 3 times of g/ml of Flos Lonicerae weight, obtains Flos Lonicerae extractive solution.
The wherein preparation of Radix Solani Melongenae extracting solution: get Radix Solani Melongenae appropriate, be ground into coarse powder, take coarse powder 80g, heating decocts extracts, and Extracting temperature is 100 DEG C, extracts 3 times, adds the water of 12 times amount for the 1st time, extracts 1h; Add the water of 10 times amount for 2nd time, extract 1h; Add the water of 8 times amount for 3rd time, extract 1h; Each use three layers of filtered through gauze, merging filtrate, concentrates filtrate to 3 times of g/ml of Radix Arctii weight, obtains Radix Solani Melongenae extracting solution.
The wherein preparation of royal jelly solution: royal jelly extracting lyophilized powder 0.5g, adds the water of 60 times amount, stir to obtain royal jelly solution.
The physical and chemical index of embodiment 1,2 is as follows:
Character: this product be faint yellow, crystal clear, viscosity are suitable for, fine and smooth evenly, stretchability and the good gel of absorbability.
Dip a small amount of gel with pH reagent paper, recording pH value is 6-7.
Gel is packaged in respectively in transparence cosmetic bottle, observes without lamination in the refrigerator cold-storages about a week of 4 DEG C.In the calorstat of 55 DEG C, place 24h, gel is without the phenomenon such as layering, emulsifying is spoiled.
Gel is packaged in 3000r/min in centrifuge tube, centrifugal 20min, without lamination.
Embodiment 1,2 made gels are placed in bottle for cosmetics, and room temperature leaves standstill investigation 6 months, without lamination, with after feel unchanged, abnormal smells from the patient is unchanged, without denaturalization phenomenon.
Irritation test, anaphylaxis are tested
White mice back cuts off hair, smears the gel prepared by embodiment 1,2 respectively in cutting plucked position, and is not coated with position and compares, and result does not have zest and anaphylaxis.
Anti-acne effect is tested
Clinical experiment contrast is carried out in blemish clearing gel agent obtained for embodiment 1,2 and existing product for resolving poxes, and experimental result is as shown in table 1:
Table 1:
This gel resultant effect is investigated
Trial effect is below utilized to carry out the effect of the gel that Evaluation operation example 1,2 produces.Adopt public-opinion poll point system, choose 40 15-40 year age bracket women as object on probation, be divided into arbitrarily two groups, put face on the skin with the gel of embodiment 1,2 preparation respectively.Every day uses twice, and service time is two months.Every result of use total score is 5 points: 5 be divided into best result, represents very well, very satisfaction; 4 are divided into better; 3 are divided into and can accept; Less than 3 points is bad, can not accept.It is below every average.The results are shown in Table 2:
Table 2 resultant effect is investigated
In sum, this gel stretchability, absorbability are good, have good anti-acne, moisture retention, and during use, sensation is gentle comfortable, ruddy, glossy by rear skin exquisiteness, has the effect of anti-acne, skin protection.
The present invention is not limited to above-described embodiment; do not departing under the present invention's spirit and real situation thereof; those of ordinary skill in the art can make various corresponding change and distortion according to the present invention; these are tackled amendment that the present invention carries out mutually or equivalently to replace, and it all should be encompassed in the scope of claim of the present invention protection.
Claims (9)
1. the agent of Chinese medicine blemish clearing gel, is characterized in that, containing following material and content thereof in the agent of described Chinese medicine blemish clearing gel:
Fructus Arctii extracting solution 0.5-5ml
Pine needle extract 0.5-5ml
Flos Chrysanthemi Indici extracting solution 0.5-5ml
Radix Solani Melongenae extracting solution 0.5-5ml
Flos Lonicerae extractive solution 0.5-5ml
Royal jelly solution 0.5-5ml
Sodium carboxymethyl cellulose 0.01-1.5g
Sodium alginate 0.01-1g
The cross linked polymer QM 0.01-1g of polyvinyl methyl ethermaleic anhydride/acrylic acid methyl ester. and decadinene
Glycerol 1-6ml
1,2-PD 1-6ml
Essence 0.01-0.05g
75% ethyl hydroxybenzoate alcoholic solution 0.01-1.5g
Distilled water 21-35ml.
2. a kind of Chinese medicine blemish clearing gel according to claim 1 agent, is characterized in that: described essence is one or more in rose essence, peach flavor, flavoring pineapple essence, Fructus Citri Limoniae essence, green cucumber essence, jasmin essence, osmanthus flower fragrance.
3. a Chinese medicine blemish clearing gel agent preparation method described in claim 1, comprises the steps:
Step one: get sodium carboxymethyl cellulose powder 0.01-1.5g, add 10-20ml distilled water, stirs, fully dissolves to obtain carboxymethylcellulose sodium solution;
Step 2: get sodium alginate powder 0.01-1g, adds 5-16ml distilled water, stirs, fully dissolves to obtain sodium alginate soln;
Step 3: get QM powder 0.01-1g, add 1-10ml distilled water, stirs, fully dissolves to obtain QM solution;
Step 4: by above-mentioned three kinds of solution mixing, fully stirs to obtain clear, gel substrate that viscosity is good;
Step 5: get Fructus Arctii extracting solution 0.5-5ml, pine needle extract 0.5-5ml, Flos Chrysanthemi Indici extracting solution 0.5-5ml, Flos Chrysanthemi Indici get liquid 0.5-5ml, royal jelly solution 0.5-5ml, Flos Lonicerae extractive solution 0.5-5ml, glycerol 1-6ml, 1,2-propylene glycol 1-6ml, essence 0.01-0.05g, 75% ethyl hydroxybenzoate alcoholic solution 0.01-1.5g, add in above-mentioned prepared gel-type vehicle successively, stir, make mix homogeneously, obtain the agent of Chinese medicine blemish clearing gel.
4. Chinese medicine blemish clearing gel agent preparation method according to claim 3, it is characterized in that, described Fructus Arctii extracting solution is prepared by the following method: get fresh burdock root and thinly slice, heating decocts extracts, and Extracting temperature is 80-100 DEG C, extracts 3 times, add the water of 10-16 times amount for 1st time, extract 0.5-2h; Add the water of 8-15 times amount for 2nd time, extract 0.5-2h; Add the water of 6-10 times amount for 3rd time, extract 0.5-2h; Each use three layers of filtered through gauze, merging filtrate, concentrates filtrate to 1-5 times of g/ml of Radix Arctii weight, obtains Fructus Arctii extracting solution.
5. Chinese medicine blemish clearing gel agent preparation method according to claim 3, it is characterized in that, described pine needle extract is prepared by the following method: get fresh needles, reflux, extract, 3 times, adds the water of 10-15 times amount for the 1st time, extracts 0.5-2h; Add 8-12 times of water 2nd time, extract 0.5-2h; Add 6-10 times of water 3rd time, extract 0.5-2h; Each three layers of filtered through gauze, merging filtrate, concentrates filtrate to 1-5 times of g/ml of Folium Pini weight, obtains pine needle extract.
6. Chinese medicine blemish clearing gel agent preparation method according to claim 3, it is characterized in that, described Flos Chrysanthemi Indici extracting solution is prepared by the following method: get dry Flos Chrysanthemi Indici, reflux, extract, 3 times, add 10-20 times amount 60% ethanol 1st time, soak 20-60min, extract 0.5-2h; Add 8-18 doubly 60% ethanol for 2nd time, extract 0.5-2h; Add 6-12 doubly 60% ethanol for 3rd time, extract 0.5-2h; Each three layers of filtered through gauze, merging filtrate, concentrates filtrate to 1-5 times of g/ml of Flos Chrysanthemi Indici weight, obtains Flos Chrysanthemi Indici extracting solution.
7. Chinese medicine blemish clearing gel agent preparation method according to claim 3, it is characterized in that, described Flos Lonicerae extractive solution is prepared by the following method: extracting honeysuckle dry flower, reflux, extract, 3 times, adds 65% ethanol of 10-18 times amount for the 1st time, extracts 0.5-2h; Add 8-15 doubly 60% ethanol for 2nd time, extract 0.5-2h; Add 6-10 doubly 60% ethanol for 3rd time, extract 0.5-2h; Each three layers of filtered through gauze, merging filtrate, concentrates filtrate to 1-5 times of g/ml of Flos Lonicerae weight, obtains Flos Lonicerae extractive solution.
8. Chinese medicine blemish clearing gel agent preparation method according to claim 3, it is characterized in that, described Radix Solani Melongenae extracting solution is prepared by the following method: get Radix Solani Melongenae, be ground into coarse powder, heating decocts extracts, and Extracting temperature is 80-100 DEG C, extract 3 times, add the water of 10-15 times amount for the 1st time, extract 0.5-2h; Add the water of 8-12 times amount for 2nd time, extract 0.5-2h; Add the water of 6-10 times amount for 3rd time, extract 0.5-2h; Each use three layers of filtered through gauze, merging filtrate, concentrates filtrate to 1-5 times of g/ml of Radix Arctii weight, obtains Radix Solani Melongenae extracting solution.
9. Chinese medicine blemish clearing gel agent preparation method according to claim 3, it is characterized in that, described royal jelly solution is prepared by the following method: royal jelly extracting lyophilized powder, adds the water of 50-100 times amount, and stir to obtain royal jelly solution.
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| CN201410771987.7A CN104434740B (en) | 2014-12-16 | 2014-12-16 | A kind of Chinese medicine blemish clearing gel agent and preparation method thereof |
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Cited By (8)
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| CN106038423A (en) * | 2016-07-27 | 2016-10-26 | 陕西仁康药业有限公司 | Acne and scar removal gel and method for preparing same |
| CN107320403A (en) * | 2017-08-29 | 2017-11-07 | 山东维赫生物科技有限公司 | A kind of Chloranthus glaber shower condensation |
| CN107496792A (en) * | 2017-08-29 | 2017-12-22 | 皖南医学院 | A kind of gel of antiphlogistic antibacterial treatment onychomycosis and preparation method thereof |
| CN107550808A (en) * | 2017-08-29 | 2018-01-09 | 皖南医学院 | A kind of moisturizing baby's hip pad emulsion of diaper rash of dispelling and preparation method thereof |
| CN107929150A (en) * | 2017-12-23 | 2018-04-20 | 芜湖皖江知识产权运营中心有限公司 | A kind of pox-eliminating whitening gel |
| CN107929210A (en) * | 2017-12-23 | 2018-04-20 | 芜湖皖江知识产权运营中心有限公司 | A kind of anti-acne moisturizing gel and preparation method thereof |
| CN107961189A (en) * | 2017-12-23 | 2018-04-27 | 芜湖皖江知识产权运营中心有限公司 | A kind of preparation method of pox-eliminating whitening gel |
| CN113018238A (en) * | 2021-03-23 | 2021-06-25 | 皖南医学院 | Anti-bacterial, anti-inflammatory, refreshing and skin-benefiting acne-removing gel and preparation method thereof |
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| CN106038423A (en) * | 2016-07-27 | 2016-10-26 | 陕西仁康药业有限公司 | Acne and scar removal gel and method for preparing same |
| CN106038423B (en) * | 2016-07-27 | 2019-01-08 | 陕西仁康药业有限公司 | A kind of anti-acne, except scar gel and preparation method thereof |
| CN107320403A (en) * | 2017-08-29 | 2017-11-07 | 山东维赫生物科技有限公司 | A kind of Chloranthus glaber shower condensation |
| CN107496792A (en) * | 2017-08-29 | 2017-12-22 | 皖南医学院 | A kind of gel of antiphlogistic antibacterial treatment onychomycosis and preparation method thereof |
| CN107550808A (en) * | 2017-08-29 | 2018-01-09 | 皖南医学院 | A kind of moisturizing baby's hip pad emulsion of diaper rash of dispelling and preparation method thereof |
| CN107496792B (en) * | 2017-08-29 | 2020-05-26 | 皖南医学院 | Gel for treating onychomycosis by diminishing inflammation and resisting bacteria and preparation method thereof |
| CN107929150A (en) * | 2017-12-23 | 2018-04-20 | 芜湖皖江知识产权运营中心有限公司 | A kind of pox-eliminating whitening gel |
| CN107929210A (en) * | 2017-12-23 | 2018-04-20 | 芜湖皖江知识产权运营中心有限公司 | A kind of anti-acne moisturizing gel and preparation method thereof |
| CN107961189A (en) * | 2017-12-23 | 2018-04-27 | 芜湖皖江知识产权运营中心有限公司 | A kind of preparation method of pox-eliminating whitening gel |
| CN113018238A (en) * | 2021-03-23 | 2021-06-25 | 皖南医学院 | Anti-bacterial, anti-inflammatory, refreshing and skin-benefiting acne-removing gel and preparation method thereof |
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Inventor after: Sun Shuping Inventor after: Zhao Mei Inventor after: Li Kangcai Inventor after: Zhang Min Inventor after: Wu Yu Inventor after: Chen Xiaoli Inventor after: Qian Zhangchao Inventor after: Chai Zhilong Inventor before: Sun Shuping Inventor before: Zhao Mei Inventor before: Li Kangcai Inventor before: Zhang Min Inventor before: Wu Yu Inventor before: Chen Xiaoli Inventor before: Qian Zhangchao Inventor before: Chai Zhilong |
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Effective date of registration: 20190329 Address after: Room B606, Building No. 2, Dongjiaomin Lane, Dongcheng District, Beijing, 100000 Patentee after: Beijing Huadan Hospital Investment Management Co., Ltd. Address before: 241000 Pharmaceutical Department, School of Pharmacy, Southern Anhui Medical College, 22 Wenchang West Road, Wuhu Higher Education Park, Anhui Province Patentee before: Wannan Medical College |