CN111450036A - Product composition containing houttuynia cordata and application of product composition in skin care products - Google Patents

Product composition containing houttuynia cordata and application of product composition in skin care products Download PDF

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CN111450036A
CN111450036A CN202010388032.9A CN202010388032A CN111450036A CN 111450036 A CN111450036 A CN 111450036A CN 202010388032 A CN202010388032 A CN 202010388032A CN 111450036 A CN111450036 A CN 111450036A
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extract
houttuynia cordata
product composition
composition
root extract
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陈允斌
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Sichuan Materia Medica Health Technology Co.,Ltd.
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
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  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
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  • Microbiology (AREA)
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  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a product composition containing houttuynia cordata, which comprises the following components in percentage by mass: 10-40% of houttuynia cordata extract, 15-22% of astragalus membranaceus root extract, 8-13% of radix sileris root extract, 12-18% of calendula officinalis extract, 10-16% of albizia julibrissin flower extract and 15-21% of gastrodia elata root extract. Has the advantages of improving skin quality and eliminating skin acne. The invention also discloses application of the product composition containing the houttuynia cordata in skin care products.

Description

Product composition containing houttuynia cordata and application of product composition in skin care products
Technical Field
The invention relates to the technical field of skin care, in particular to a product composition containing houttuynia cordata and application thereof in skin care products.
Background
Many personal care products are now available to consumers primarily for the purpose of improving skin health and/or physical appearance. Many of these skin care products are directed to delaying, reducing, or even eliminating skin wrinkles and other histological changes, which are generally associated with natural aging of the skin and environmental damage to human skin. A variety of compounds have been described in current research for regulating skin conditions, including regulating fine lines, wrinkles and other skin irregularities, roughness problems associated with aging, photodamage, and the like.
The skin is subject to insults by many extrinsic and intrinsic factors. Extrinsic factors include ultraviolet radiation (e.g., from exposure to sunlight), environmental pollution, wind, heat, low humidity, irritating surfactants, abrasives, etc. Intrinsic factors include chronic aging, endocrine disorders and other biochemical changes within the skin. These extrinsic and intrinsic factors lead to the appearance of wrinkles, spots, puffiness, acne and the formation of pox marks or pits at a later stage of the skin.
Disclosure of Invention
In order to solve the problems in the prior art, the invention provides a product composition containing houttuynia cordata and application thereof in skin care products, and the product composition has the advantages of improving skin quality, eliminating skin acne and the like.
In order to achieve the purpose, the invention adopts the technical scheme that: a product composition containing houttuynia cordata, which comprises the following components in percentage by mass: 10-40% of houttuynia cordata extract, 15-22% of astragalus membranaceus root extract, 8-13% of radix sileris root extract, 12-18% of calendula officinalis extract, 10-16% of albizia julibrissin flower extract and 15-21% of gastrodia elata root extract.
Preferably, the composition further comprises tortoise shell powder 3-5%.
Preferably, the composition further comprises 6-7% of coptis extract.
Herba Houttuyniae has effects of clearing away heat and toxic materials, relieving swelling and treating sore, and can be used for treating pyocutaneous disease and pyogenic infection; radix astragali has effects in invigorating qi, invigorating yang, invigorating defensive system, consolidating superficial resistance, inducing diuresis, relieving swelling, promoting wound healing, and promoting granulation; radix Saposhnikoviae has effects in relieving exterior syndrome, inducing perspiration, dispelling pathogenic wind, and removing dampness; the calendula can prevent pigmentation, enhance skin luster and elasticity, slow aging and avoid skin relaxation and wrinkles; flos Albizziae has effects of treating eye diseases and neurasthenia; the rhizoma gastrodiae has the efficacy of eliminating carbuncle and swelling; the tortoise plastron and the coptis are externally applied to the affected part to treat sore and furuncle, skin ulceration, pus running and water running, and unhealed for a long time; coptis root, rhizoma Coptidis, being bitter and cold in nature, can be used externally to treat eczema, eczema and suppuration in the auditory canal.
Use of a product composition comprising houttuynia cordata in a skin care product comprising the composition according to any one of claims 1 to 3 and conventional adjuvants.
Preferably, the conventional auxiliary materials comprise a humectant, a thickener, a preservative, an emulsifier and deionized water.
Preferably, the skin care product comprises a facial mask, a face cream, an eye cream, a body lotion and a hand cream.
The invention has the beneficial effects that:
the compound skin external product has the effects of relieving swelling, treating sore, promoting tissue regeneration, preventing skin infection and the like by adding the traditional Chinese medicines such as the houttuynia cordata, the astragalus membranaceus root, the divaricate saposhnikovia root, the calendula, the albizia flower and the rhizoma gastrodiae into the composition, wherein the calendula has the effects of preventing pigmentation, improving skin luster and elasticity, slowing down aging, avoiding skin relaxation and wrinkle formation, so that the product has the skin care functions of moistening, brightening the skin, improving wrinkles, increasing elasticity and the like in a skin care product, is suitable for adolescents in adolescence, and is suitable for reducing the problems that the adolescents cannot be cured for a long time and leave acne marks and the like.
Detailed Description
The following provides a detailed description of embodiments of the invention.
Example 1:
a product composition containing houttuynia cordata, which comprises the following components in percentage by mass: 40% of houttuynia cordata extract, 15% of astragalus membranaceus root extract, 8% of saposhnikovia divaricata root extract, 12% of calendula officinalis extract, 10% of albizia julibrissin flower extract and 15% of gastrodia elata root extract.
The composition also includes tortoise shell powder 3%.
The composition also comprises 6% of coptis extract.
Example 2:
a product composition containing houttuynia cordata, which comprises the following components in percentage by mass: 25% of houttuynia cordata extract, 18% of astragalus membranaceus root extract, 10.5% of saposhnikovia divaricata root extract, 14.5% of calendula officinalis extract, 13.5% of albizia julibrissin flower extract and 18.5% of gastrodia elata root extract.
The composition also includes tortoise shell powder 4%.
The composition also comprises 6.5% of coptis extract.
Example 3:
a product composition containing houttuynia cordata, which comprises the following components in percentage by mass: 10% of houttuynia cordata extract, 22% of astragalus membranaceus root extract, 13% of saposhnikovia divaricata root extract, 18% of calendula officinalis extract, 16% of albizia julibrissin flower extract and 21% of gastrodia elata root extract.
The composition also includes tortoise shell powder 5%.
The composition also comprises 7% of coptis extract.
Example 4:
a product composition containing houttuynia cordata, which comprises the following components in percentage by mass: 40% of houttuynia cordata extract, 15% of astragalus membranaceus root extract, 8% of saposhnikovia divaricata root extract, 12% of calendula officinalis extract, 10% of albizia julibrissin flower extract and 15% of gastrodia elata root extract.
The composition also includes tortoise shell powder 3%.
The composition also comprises 6% of coptis extract.
The embodiment also provides application of a facial mask prepared according to the compound skin external preparation, and the facial mask comprises 94% of conventional auxiliary materials and 6% of the compound skin external preparation in percentage by mass. In particular to 0.6g of compound skin external preparation and 9.4g of conventional auxiliary materials.
Conventional adjuvants include humectant, thickener, antiseptic, emulsifier and deionized water.
Wherein the humectant is one or more of butanediol, betaine, biogum-1, 2-pentanediol and 1, 2-hexanediol; the thickener accounts for 0.4 percent of the mass of the conventional auxiliary materials.
Example 5:
a product composition containing houttuynia cordata, which comprises the following components in percentage by mass: 25% of houttuynia cordata extract, 18% of astragalus membranaceus root extract, 10.5% of saposhnikovia divaricata root extract, 14.5% of calendula officinalis extract, 13.5% of albizia julibrissin flower extract and 18.5% of gastrodia elata root extract.
The composition also includes tortoise shell powder 4%.
The composition also comprises 6.5% of coptis extract.
The embodiment also provides application of a facial mask prepared according to the compound skin external preparation, and the facial mask comprises 90% of conventional auxiliary materials and 10% of the compound skin external preparation in percentage by mass. In particular to 1g of compound skin external preparation and 9g of conventional auxiliary materials.
Conventional adjuvants include humectant, thickener, antiseptic, emulsifier and deionized water.
Wherein the humectant is one or more of butanediol, betaine, biogum-1, 2-pentanediol and 1, 2-hexanediol; the thickener accounts for 0.3 percent of the mass of the conventional auxiliary materials.
Example 6:
a product composition containing houttuynia cordata, which comprises the following components in percentage by mass: 10% of houttuynia cordata extract, 22% of astragalus membranaceus root extract, 13% of saposhnikovia divaricata root extract, 18% of calendula officinalis extract, 16% of albizia julibrissin flower extract and 21% of gastrodia elata root extract.
The composition also includes tortoise shell powder 5%.
The composition also comprises 7% of coptis extract.
The embodiment also provides application of a facial mask prepared according to the compound skin external preparation, and the facial mask comprises 85% of conventional auxiliary materials and 15% of the compound skin external preparation in percentage by mass. In particular to 1.5g of compound skin external preparation and 8.5g of conventional auxiliary materials.
Conventional adjuvants include humectant, thickener, antiseptic, emulsifier and deionized water.
Wherein the humectant is one or more of butanediol, betaine, biogum-1, 2-pentanediol and 1, 2-hexanediol; the thickener accounts for 0.2 percent of the mass of the conventional auxiliary materials.
Example 7:
a product composition containing houttuynia cordata, which comprises the following components in percentage by mass: 40% of houttuynia cordata extract, 15% of astragalus membranaceus root extract, 8% of saposhnikovia divaricata root extract, 12% of calendula officinalis extract, 10% of albizia julibrissin flower extract and 15% of gastrodia elata root extract.
The composition also includes tortoise shell powder 3%.
The composition also comprises 6% of coptis extract.
The embodiment also provides application of a cream prepared according to the compound skin external preparation, and the cream comprises 95% of conventional auxiliary materials and 5% of the compound skin external preparation in percentage by mass. In particular to 0.5g of compound skin external preparation and 9.5g of conventional auxiliary materials.
Conventional adjuvants include humectant, thickener, antiseptic, emulsifier and deionized water.
Wherein the humectant is one or more of butanediol, betaine, biogum-1, 2-pentanediol and 1, 2-hexanediol; the thickener accounts for 0.8 percent of the mass of the conventional auxiliary materials.
Example 8:
a product composition containing houttuynia cordata, which comprises the following components in percentage by mass: 25% of houttuynia cordata extract, 18% of astragalus membranaceus root extract, 10.5% of saposhnikovia divaricata root extract, 14.5% of calendula officinalis extract, 13.5% of albizia julibrissin flower extract and 18.5% of gastrodia elata root extract.
The composition also includes tortoise shell powder 4%.
The composition also comprises 6.5% of coptis extract.
The embodiment also provides application of a cream prepared according to the compound skin external preparation, and the cream comprises 90% of conventional auxiliary materials and 10% of the compound skin external preparation in percentage by mass. In particular to 1g of compound skin external preparation and 9g of conventional auxiliary materials.
Conventional adjuvants include humectant, thickener, antiseptic, emulsifier and deionized water.
Wherein the humectant is one or more of butanediol, betaine, biogum-1, 2-pentanediol and 1, 2-hexanediol; the thickener accounts for 0.6 percent of the mass of the conventional auxiliary materials.
Example 9:
a product composition containing houttuynia cordata, which comprises the following components in percentage by mass: 10% of houttuynia cordata extract, 22% of astragalus membranaceus root extract, 13% of saposhnikovia divaricata root extract, 18% of calendula officinalis extract, 16% of albizia julibrissin flower extract and 21% of gastrodia elata root extract.
The composition also includes tortoise shell powder 5%.
The composition also comprises 7% of coptis extract.
The embodiment also provides application of a cream prepared according to the compound skin external preparation, and the cream comprises 80% of conventional auxiliary materials and 20% of the compound skin external preparation in percentage by mass. In particular to 2g of compound skin external preparation and 8g of conventional auxiliary materials.
Conventional adjuvants include humectant, thickener, antiseptic, emulsifier and deionized water.
Wherein the humectant is one or more of butanediol, betaine, biogum-1, 2-pentanediol and 1, 2-hexanediol; the thickener accounts for 0.5 percent of the mass of the conventional auxiliary materials.
Example 10:
a product composition containing houttuynia cordata, which comprises the following components in percentage by mass: 10% of houttuynia cordata extract, 22% of astragalus membranaceus root extract, 13% of saposhnikovia divaricata root extract, 18% of calendula officinalis extract, 16% of albizia julibrissin flower extract and 21% of gastrodia elata root extract.
The composition also includes tortoise shell powder 5%.
The composition also comprises 7% of coptis extract.
The embodiment also provides application of the eye cream prepared according to the compound skin external preparation, and the eye cream comprises 97% of conventional auxiliary materials and 3% of the compound skin external preparation in percentage by mass. In particular to 0.3g of compound skin external preparation and 9.7g of conventional auxiliary materials.
Conventional adjuvants include humectant, thickener, antiseptic, emulsifier and deionized water.
Wherein the humectant is one or more of butanediol, betaine, biogum-1, 2-pentanediol and 1, 2-hexanediol; the thickener accounts for 0.3 percent of the mass of the conventional auxiliary materials.
Example 11:
a product composition containing houttuynia cordata, which comprises the following components in percentage by mass: 10% of houttuynia cordata extract, 22% of astragalus membranaceus root extract, 13% of saposhnikovia divaricata root extract, 18% of calendula officinalis extract, 16% of albizia julibrissin flower extract and 21% of gastrodia elata root extract.
The composition also includes tortoise shell powder 5%.
The composition also comprises 7% of coptis extract.
The embodiment also provides application of the body lotion prepared according to the compound skin external preparation, and the body lotion comprises 95% of conventional auxiliary materials and 5% of the compound skin external preparation in percentage by mass. In particular to 0.5g of compound skin external preparation and 9.5g of conventional auxiliary materials.
Conventional adjuvants include humectant, thickener, antiseptic, emulsifier and deionized water.
Wherein the humectant is one or more of butanediol, betaine, biogum-1, 2-pentanediol and 1, 2-hexanediol; the thickener accounts for 0.2 percent of the mass of the conventional auxiliary materials.
Example 12:
a product composition containing houttuynia cordata, which comprises the following components in percentage by mass: 10% of houttuynia cordata extract, 22% of astragalus membranaceus root extract, 13% of saposhnikovia divaricata root extract, 18% of calendula officinalis extract, 16% of albizia julibrissin flower extract and 21% of gastrodia elata root extract.
The composition also includes tortoise shell powder 5%.
The composition also comprises 7% of coptis extract.
The embodiment also provides application of the hand cream prepared according to the compound skin external preparation, and the hand cream comprises 96% of conventional auxiliary materials and 4% of the compound skin external preparation in percentage by mass. In particular to 0.4g of compound skin external preparation and 0.96g of conventional auxiliary materials.
Conventional adjuvants include humectant, thickener, antiseptic, emulsifier and deionized water.
Wherein the humectant is one or more of butanediol, betaine, biogum-1, 2-pentanediol and 1, 2-hexanediol; the thickener accounts for 0.1 percent of the mass of the conventional auxiliary materials.
And (3) efficacy verification:
aiming at the products of the embodiments, skin care varieties are classified into facial masks, face creams, eye creams, body lotions and hand creams, test objects are selected aiming at different kinds of skin care products, and the screening conditions of the test objects are as follows: age 14-25 years, gender male-female ratio 1: and 2, dividing a product group and a placebo, wherein 30 product groups and 30 placebo groups are selected for each product, and the product groups and the placebo groups are used in the same method. The using cycle of the mask is 2 times per week, 15 minutes each time, and four weeks; the service cycle of the face cream is four weeks, and the face cream is uniformly coated on the face after being cleaned in the morning and evening to avoid entering eyes; the using cycle of the eye cream is four weeks, and the eye cream is applied to the eye periphery after face cleaning in the morning and evening to avoid entering eyes; the using period of the body lotion is four weeks, and the body lotion is rubbed and smeared on the whole body after bathing every day; the use period of the hand cream is 4 weeks, and the hand cream is used after hand washing.
The improvement effect mainly takes the chief complaint of a test object as the standard, and in order to avoid the influence of subjective consciousness on the accuracy of a test result, before the test, the product group and the placebo group are subjected to blind test by random numbers and only recorded on a host test party. After the test is finished, the test object is revisited, and whether the facial skin moisturizes and the facial acne mark is improved or not is mainly recorded aiming at the facial mask test object; mainly recording whether facial skin moisturizes and facial acne marks and pockmarks fade or not aiming at a facial cream test object; for the body cream test subjects, the improvement of body skin elasticity and wrinkles was mainly recorded; for the eye cream test object, mainly recording whether the improvement of the bags under the eyes and the black eyes exists; for the test object of the hand cream, whether the hand skin moisturizes is improved or not is mainly recorded, the number of the improvement is finally recorded, and the proportion of the number of the improvement to the total number is calculated, so that the effective rate is obtained.
Effective rate is 100% of main complaint obvious effective samples/effective test samples
The experimental effects of the above examples are as follows:
experimental effect comparison table
Figure BDA0002484809520000091
In the experimental process, the compound skin external preparation and the skin care product prepared by the compound skin external preparation can generate certain effects under different crowds, have the most obvious effect on whelks, acnes and comedos, have certain effect on relieving skin relaxation for older experimental subjects, and have the effects of removing acne marks and whitening for younger experimental subjects. Compared with a placebo group, the product of the invention has remarkable improvement on various efficacies.
The above-mentioned embodiments only express the specific embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the present invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention.

Claims (6)

1. A product composition containing houttuynia cordata is characterized by comprising the following components in percentage by mass: 10-40% of houttuynia cordata extract, 15-22% of astragalus membranaceus root extract, 8-13% of radix sileris root extract, 12-18% of calendula officinalis extract, 10-16% of albizia julibrissin flower extract and 15-21% of gastrodia elata root extract.
2. The houttuynia cordata Thunb-containing product composition according to claim 1, wherein the composition further comprises tortoise shell powder 3-5%.
3. The houttuynia cordata-containing product composition according to claim 2, wherein the composition further comprises 6-7% of coptis chinensis extract.
4. Use of a product composition comprising houttuynia cordata in a skin care product, wherein the skin care product comprises the composition of any one of claims 1 to 3 and conventional adjuvants.
5. The use of a product composition comprising houttuynia cordata Thunb as claimed in claim 4, wherein the conventional adjuvants comprise a humectant, a thickener, a preservative, an emulsifier and deionized water.
6. The use of the product composition comprising houttuynia cordata Thunb as claimed in claim 4, wherein the skin care product comprises facial mask, face cream, eye cream, body lotion and hand cream.
CN202010388032.9A 2020-05-09 2020-05-09 Product composition containing houttuynia cordata and application of product composition in skin care products Pending CN111450036A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1857513A (en) * 2006-03-13 2006-11-08 张世麟 Chinese medicine composition for strengthening immunity, beautifying and treating skin disease
CN107789301A (en) * 2017-12-06 2018-03-13 广州赛莱拉干细胞科技股份有限公司 A kind of anti-acne skin care compositions and its application
CN110292546A (en) * 2019-07-25 2019-10-01 重庆菩璞生物科技有限公司 A kind of composition and its preparation method and application being used to prepare coptis facial mask liquid

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1857513A (en) * 2006-03-13 2006-11-08 张世麟 Chinese medicine composition for strengthening immunity, beautifying and treating skin disease
CN107789301A (en) * 2017-12-06 2018-03-13 广州赛莱拉干细胞科技股份有限公司 A kind of anti-acne skin care compositions and its application
CN110292546A (en) * 2019-07-25 2019-10-01 重庆菩璞生物科技有限公司 A kind of composition and its preparation method and application being used to prepare coptis facial mask liquid

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
广州万物本草健康科技有限公司: "《国产非特殊用途化妆品备案信息服务平台》", 26 October 2018 *

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