CN106986862A - 丙型肝炎抑制剂及其用途 - Google Patents

丙型肝炎抑制剂及其用途 Download PDF

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Publication number
CN106986862A
CN106986862A CN201610903761.7A CN201610903761A CN106986862A CN 106986862 A CN106986862 A CN 106986862A CN 201610903761 A CN201610903761 A CN 201610903761A CN 106986862 A CN106986862 A CN 106986862A
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CN
China
Prior art keywords
benzofuran
cyclopropyl
fluorophenyl
imidazol
alkyl
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Pending
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CN201610903761.7A
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English (en)
Chinese (zh)
Inventor
C.J.梅林
J.K.普拉特
W.A.卡罗尔
刘大春
D.A.德贝本纳
D.K.哈钦森
M.D.塔法诺
T.W.罗克维
U.谢恩
A.帕尔
A.维特
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Abbott GmbH and Co KG
AbbVie Inc
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Abbott GmbH and Co KG
AbbVie Inc
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Publication of CN106986862A publication Critical patent/CN106986862A/zh
Pending legal-status Critical Current

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    • C07—ORGANIC CHEMISTRY
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    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
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    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
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    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201610903761.7A 2010-12-22 2011-12-16 丙型肝炎抑制剂及其用途 Pending CN106986862A (zh)

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US9303020B2 (en) * 2012-02-08 2016-04-05 Bristol-Myers Squibb Company Compounds for the treatment of hepatitis C
WO2014167008A1 (en) 2013-04-12 2014-10-16 Bayer Cropscience Ag Novel triazolinthione derivatives
JP6397483B2 (ja) 2013-04-12 2018-09-26 バイエル・クロップサイエンス・アクチェンゲゼルシャフト 新規トリアゾール誘導体
CA2909213A1 (en) 2013-04-12 2014-10-16 Bayer Cropscience Aktiengesellschaft Novel triazole derivatives
PL3043803T3 (pl) 2013-09-11 2022-11-07 Emory University Kompozycje nukleotydowe i nukleozydowe oraz ich zastosowanie
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CA2822357A1 (en) 2012-06-28
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