CN106701698B - 羰基还原酶、突变体及其在制备抗真菌类药物中间体中的应用 - Google Patents
羰基还原酶、突变体及其在制备抗真菌类药物中间体中的应用 Download PDFInfo
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- C12N9/0004—Oxidoreductases (1.)
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- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
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CN110713991B (zh) * | 2018-07-13 | 2022-01-25 | 中国科学院天津工业生物技术研究所 | 羰基还原酶及其突变体在茚达特罗药物中间体合成中的应用 |
CN111118072A (zh) * | 2020-01-14 | 2020-05-08 | 长兴制药股份有限公司 | 一种酶法制备恩沙替尼中间体的方法 |
CN113174377B (zh) * | 2021-04-28 | 2022-11-25 | 华东理工大学 | 羰基还原酶、突变体及其在制备地尔硫卓中间体中的应用 |
CN113355366B (zh) * | 2021-05-07 | 2022-12-20 | 三峡大学 | 一种多酶级联制备2-苯乙醇的方法 |
CN115927224A (zh) * | 2021-08-05 | 2023-04-07 | 上海医药工业研究院 | 一种羰基还原酶突变体及其应用 |
CN117305258B (zh) * | 2023-09-27 | 2024-05-24 | 四川大学 | 手性内酯化合物的合成方法及羰基还原酶ChKRED20突变体和应用 |
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