CN106488916A - 作为pde抑制剂的新型2,5‑取代的嘧啶类 - Google Patents

作为pde抑制剂的新型2,5‑取代的嘧啶类 Download PDF

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Publication number
CN106488916A
CN106488916A CN201580038254.5A CN201580038254A CN106488916A CN 106488916 A CN106488916 A CN 106488916A CN 201580038254 A CN201580038254 A CN 201580038254A CN 106488916 A CN106488916 A CN 106488916A
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alkyl
alkylene
pyrimidin
compound
mmol
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Chinese (zh)
Inventor
I.科内茨基
T.克兰
F.雅各布
A.纳迪
C.黑斯林格
A.韦尔伯斯
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Gruenenthal GmbH
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Gruenenthal GmbH
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    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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CN201580038254.5A 2014-07-16 2015-07-16 作为pde抑制剂的新型2,5‑取代的嘧啶类 Pending CN106488916A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14002451.4 2014-07-16
EP14002451 2014-07-16
PCT/EP2015/001475 WO2016008592A1 (en) 2014-07-16 2015-07-16 Novel 2,5-substituted pyrimidines as pde inhibitors

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CN106488916A true CN106488916A (zh) 2017-03-08

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US9315490B2 (en) 2016-04-19
JP6726655B2 (ja) 2020-07-22
EP3169680A1 (en) 2017-05-24
MX2017000522A (es) 2017-05-01
IL250025A0 (en) 2017-03-30
CO2017001523A2 (es) 2017-05-10
US20160024053A1 (en) 2016-01-28
WO2016008592A1 (en) 2016-01-21
BR112017000826A2 (pt) 2017-12-05
TW201609708A (zh) 2016-03-16
AR101197A1 (es) 2016-11-30
KR20170032420A (ko) 2017-03-22
EP3415509A1 (en) 2018-12-19
PE20170119A1 (es) 2017-03-30
MX366840B (es) 2019-07-26
CA2955062A1 (en) 2016-01-21
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ZA201701132B (en) 2019-07-31
JP2017520600A (ja) 2017-07-27

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