CN105979930B - 药物递送系统 - Google Patents

药物递送系统 Download PDF

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Publication number
CN105979930B
CN105979930B CN201480067300.XA CN201480067300A CN105979930B CN 105979930 B CN105979930 B CN 105979930B CN 201480067300 A CN201480067300 A CN 201480067300A CN 105979930 B CN105979930 B CN 105979930B
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CN
China
Prior art keywords
vinyl acetate
sheath
drug delivery
ethylene
release
Prior art date
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Application number
CN201480067300.XA
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English (en)
Chinese (zh)
Other versions
CN105979930A (zh
Inventor
W.J.H.费尔赫文
W.德格拉夫
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme BV
Original Assignee
MSD Oss BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Publication of CN105979930A publication Critical patent/CN105979930A/zh
Application granted granted Critical
Publication of CN105979930B publication Critical patent/CN105979930B/zh
Active legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201480067300.XA 2013-12-11 2014-12-08 药物递送系统 Active CN105979930B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361914500P 2013-12-11 2013-12-11
EP13196737 2013-12-11
US61/914500 2013-12-11
EP13196737.4 2013-12-12
PCT/EP2014/076823 WO2015086491A1 (en) 2013-12-11 2014-12-08 Drug delivery system.

Publications (2)

Publication Number Publication Date
CN105979930A CN105979930A (zh) 2016-09-28
CN105979930B true CN105979930B (zh) 2019-11-19

Family

ID=49759119

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480067300.XA Active CN105979930B (zh) 2013-12-11 2014-12-08 药物递送系统

Country Status (23)

Country Link
US (1) US10413504B2 (https=)
EP (1) EP3079660B1 (https=)
JP (1) JP6251396B2 (https=)
KR (1) KR101808977B1 (https=)
CN (1) CN105979930B (https=)
AP (1) AP2016009223A0 (https=)
AU (1) AU2014363724B2 (https=)
BR (1) BR112016013325B1 (https=)
CA (1) CA2931559C (https=)
CR (1) CR20160261A (https=)
DO (1) DOP2016000132A (https=)
EA (1) EA031802B1 (https=)
HK (1) HK1224208A1 (https=)
IL (1) IL245544A0 (https=)
MA (1) MA39059A1 (https=)
MD (1) MD20160079A2 (https=)
MX (1) MX2016007681A (https=)
PE (1) PE20160680A1 (https=)
PH (1) PH12016501083A1 (https=)
SG (1) SG11201604660VA (https=)
SV (1) SV2016005214A (https=)
TW (1) TW201607563A (https=)
WO (1) WO2015086491A1 (https=)

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US10413504B2 (en) 2013-12-11 2019-09-17 Merck Sharp & Dohme Corp. Intravaginal ring drug delivery system
WO2015086489A1 (en) 2013-12-11 2015-06-18 Merck Sharp & Dohme B.V. Drug delivery system for delivery of anti-virals
WO2015094759A1 (en) 2013-12-19 2015-06-25 The Procter & Gamble Company Shaping keratin fibres using an active agent comprising at least two functional groups selected from: -c(oh)- and -c(=o)oh
EP3082735B1 (en) 2013-12-19 2018-05-02 The Procter and Gamble Company Shaping keratin fibres using oxoethanoic acid and/or derivatives thereof
MX361100B (es) 2013-12-19 2018-11-27 Procter & Gamble Modelado de fibras de queratina mediante el uso de un azucar.
MX376963B (es) 2013-12-19 2025-03-07 Procter & Gamble Modelado de fibras de queratina mediante el uso de éster de carbonato.
CN105828786B (zh) 2013-12-19 2020-07-07 宝洁公司 使用包含选自-c(＝o)-、-c(＝o)-h和-c(＝o)-o-的官能团的an活性剂使角蛋白纤维成形
EP3082750A1 (en) 2013-12-19 2016-10-26 The Procter & Gamble Company Shaping keratin fibres using a reducing composition and a fixing composition
MX357743B (es) 2013-12-19 2018-07-23 Procter & Gamble Formacion de fibras de queratina con 2-hidroxipropano-1,2,3-acido tricarboxilico y/o 1,2,3,4-acido butanetetracarboxilico.
EP3017809A1 (en) * 2014-11-07 2016-05-11 Ferring B.V. Drug-device unit containing quinagolide
EP3297731A1 (en) 2014-12-19 2018-03-28 The Procter and Gamble Company Shaping keratin fibres using arabinose and ethylene carbonate
EP3297730A1 (en) 2014-12-19 2018-03-28 The Procter and Gamble Company Method of shaping keratin fibres
US10945931B2 (en) 2015-06-18 2021-03-16 The Procter And Gamble Company Shaping keratin fibres using dialdehyde compounds
US20180228942A1 (en) * 2015-08-11 2018-08-16 Ptt Holding Aps A delivery device
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BR112023022439A2 (pt) 2021-04-26 2023-12-26 Celanese Eva Performance Polymers Llc Dispositivo implantável para liberação sustentada de um composto de fármaco macromolecular
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CN1794974A (zh) * 2003-05-23 2006-06-28 阿克佐诺贝尔公司 药物递送体系
CN100531800C (zh) * 2004-03-24 2009-08-26 奥尔加侬股份有限公司 基于聚乙烯乙酸乙烯酯共聚物的药物递送系统

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CN100531800C (zh) * 2004-03-24 2009-08-26 奥尔加侬股份有限公司 基于聚乙烯乙酸乙烯酯共聚物的药物递送系统

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Also Published As

Publication number Publication date
EP3079660B1 (en) 2021-03-03
AU2014363724A1 (en) 2016-05-26
PH12016501083A1 (en) 2016-07-25
SV2016005214A (es) 2016-11-21
US10413504B2 (en) 2019-09-17
HK1224208A1 (zh) 2017-08-18
PE20160680A1 (es) 2016-07-31
US20150157561A1 (en) 2015-06-11
DOP2016000132A (es) 2016-07-31
CA2931559A1 (en) 2015-06-18
JP6251396B2 (ja) 2017-12-20
BR112016013325B1 (pt) 2022-11-29
AU2014363724B2 (en) 2017-02-23
SG11201604660VA (en) 2016-07-28
MX2016007681A (es) 2016-10-14
EA201691193A1 (ru) 2016-09-30
WO2015086491A1 (en) 2015-06-18
IL245544A0 (en) 2016-06-30
EA031802B1 (ru) 2019-02-28
EP3079660A1 (en) 2016-10-19
JP2016539991A (ja) 2016-12-22
CN105979930A (zh) 2016-09-28
CR20160261A (es) 2016-08-16
BR112016013325A2 (https=) 2017-08-08
MD20160079A2 (ro) 2016-10-31
TW201607563A (zh) 2016-03-01
KR101808977B1 (ko) 2017-12-13
AP2016009223A0 (en) 2016-05-31
KR20160095110A (ko) 2016-08-10
MA39059A1 (fr) 2018-08-31
CA2931559C (en) 2018-03-13

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