CN105592848A - 高剂量普利多匹定用于治疗亨廷顿舞蹈症的用途 - Google Patents

高剂量普利多匹定用于治疗亨廷顿舞蹈症的用途 Download PDF

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Publication number
CN105592848A
CN105592848A CN201480035525.7A CN201480035525A CN105592848A CN 105592848 A CN105592848 A CN 105592848A CN 201480035525 A CN201480035525 A CN 201480035525A CN 105592848 A CN105592848 A CN 105592848A
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China
Prior art keywords
patient
uhdrs
treatment
pharmaceutical composition
huntington chorea
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Pending
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CN201480035525.7A
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English (en)
Chinese (zh)
Inventor
梅拉夫·巴森
伊莱·埃亚勒
埃丝特·卢卡西维茨·哈加伊
安娜·克里斯蒂娜·斯韦恩斯多特泰格威肯伯格
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Teva Pharmaceuticals International GmbH
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Teva Pharmaceuticals International GmbH
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52105289&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN105592848(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Teva Pharmaceuticals International GmbH filed Critical Teva Pharmaceuticals International GmbH
Publication of CN105592848A publication Critical patent/CN105592848A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN201480035525.7A 2013-06-21 2014-06-19 高剂量普利多匹定用于治疗亨廷顿舞蹈症的用途 Pending CN105592848A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361837928P 2013-06-21 2013-06-21
US61/837,928 2013-06-21
US201361877832P 2013-09-13 2013-09-13
US61/877,832 2013-09-13
PCT/US2014/043204 WO2014205229A1 (en) 2013-06-21 2014-06-19 Use of high dose pridopidine for treating huntington's disease

Publications (1)

Publication Number Publication Date
CN105592848A true CN105592848A (zh) 2016-05-18

Family

ID=52105289

Family Applications (1)

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CN201480035525.7A Pending CN105592848A (zh) 2013-06-21 2014-06-19 高剂量普利多匹定用于治疗亨廷顿舞蹈症的用途

Country Status (24)

Country Link
US (1) US10322119B2 (https=)
EP (1) EP3010506B1 (https=)
JP (1) JP2016523862A (https=)
KR (1) KR102316933B1 (https=)
CN (1) CN105592848A (https=)
AU (1) AU2014281414A1 (https=)
BR (1) BR112015029918A2 (https=)
CA (1) CA2913781C (https=)
CL (1) CL2015003690A1 (https=)
DK (1) DK3010506T3 (https=)
EA (1) EA201690069A1 (https=)
ES (1) ES2879631T3 (https=)
HK (1) HK1221646A1 (https=)
HU (1) HUE054783T2 (https=)
IL (1) IL242804B (https=)
MX (1) MX384234B (https=)
PE (2) PE20160195A1 (https=)
PH (1) PH12015502691A1 (https=)
PL (1) PL3010506T3 (https=)
SG (1) SG11201509729YA (https=)
TW (1) TW201529069A (https=)
UA (1) UA122999C2 (https=)
UY (1) UY35624A (https=)
WO (1) WO2014205229A1 (https=)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109923102A (zh) * 2016-08-24 2019-06-21 普瑞尼亚医疗发展有限公司 普利多匹定用于治疗功能下降的用途
CN110012661A (zh) * 2016-08-24 2019-07-12 普瑞尼亚医疗发展有限公司 普利多匹定用于治疗肌张力障碍的用途
CN111278440A (zh) * 2017-08-14 2020-06-12 普里莱尼亚神经治疗有限公司 用普利多匹定治疗肌萎缩性脊髓侧索硬化症的方法
CN111278431A (zh) * 2017-08-30 2020-06-12 普瑞尼亚神经治疗有限公司 普利多匹定的高浓度剂型
CN113950328A (zh) * 2019-06-12 2022-01-18 普瑞尼亚神经治疗有限公司 用于治疗亨廷顿病及其症状的包含普利多匹定及其类似物的组合物

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USRE46117E1 (en) 1999-12-22 2016-08-23 Teva Pharmaceuticals International Gmbh Modulators of dopamine neurotransmission
SG188298A1 (en) 2010-09-03 2013-04-30 Ivax Int Gmbh Deuterated analogs of pridopidine useful as dopaminergic stabilizers
MX347209B (es) 2011-12-08 2017-04-19 Teva Pharmaceuticals Int Gmbh La sal de bromhidrato de pridopidina.
US11090297B2 (en) 2013-06-21 2021-08-17 Prilenia Neurotherapeutics Ltd. Pridopidine for treating huntington's disease
PE20161220A1 (es) * 2014-01-22 2016-11-23 Teva Pharmaceuticals Int Gmbh Formulaciones de pridopidina de liberacion modificada
TW201613859A (en) 2014-06-30 2016-04-16 Teva Pharma Analogs of PRIDOPIDINE, their preparation and use
EP3236964A4 (en) 2014-12-22 2018-09-19 Teva Pharmaceuticals International GmbH L-tartrate salt of pridopidine
EP4282479A3 (en) 2015-02-25 2024-02-21 Prilenia Neurotherapeutics Ltd. Use of pridopidine to treat depression or anxiety
US11471449B2 (en) 2015-02-25 2022-10-18 Prilenia Neurotherapeutics Ltd. Use of pridopidine to improve cognitive function and for treating Alzheimer's disease
CA2993183A1 (en) * 2015-07-22 2017-01-26 Teva Pharmaceuticals International Gmbh Pridopidine base formulations and their use
AR105434A1 (es) 2015-07-22 2017-10-04 Teva Pharmaceuticals Int Gmbh Proceso para preparar pridopidina
US11738012B2 (en) 2016-02-24 2023-08-29 Prilenia Neurotherapeutics Ltd. Treatment of neurodegenerative eye disease using pridopidine
AU2017326436A1 (en) 2016-09-15 2019-04-11 Prilenia Neurotherapeutics Ltd Use of pridopidine for the treatment of anxiety and depression
ES2909557T3 (es) 2016-09-16 2022-05-09 Prilenia Neurotherapeutics Ltd Utilización de la pridopidina para el tratamiento del síndrome de Rett
US12102627B2 (en) 2016-09-16 2024-10-01 Prilenia Neurotherapeutics Ltd. Use of pridopidine for treating rett syndrome
CA3050700C (en) 2017-01-20 2023-10-03 Prilenia Neurotherapeutics Ltd. Use of pridopidine for the treatment of fragile x syndrome
US12036213B2 (en) 2017-09-08 2024-07-16 Prilenia Neurotherapeutics Ltd. Pridopidine for treating drug induced dyskinesias
AU2018329628B2 (en) 2017-09-08 2021-04-22 Prilenia Neurotherapeutics Ltd. Pridopidine for treating drug induced dyskinesias
EP3917380B1 (en) * 2019-01-31 2025-03-19 F. Hoffmann-La Roche AG Assessing progression of huntington's disease
EP3920924A4 (en) 2019-02-04 2022-11-16 Prilenia Neurotherapeutics Ltd. LOW-DOSE PRIDOIDIN FOR THE TREATMENT OF PARKINSON'S DISEASE AND OTHER PARKINSONIC-RELATED DISEASES
US20220346699A1 (en) * 2019-09-17 2022-11-03 Hoffmann-La Roche Inc. Improvements in Personalized Healthcare for Patients with Movement Disorders
US20230390232A1 (en) * 2020-10-28 2023-12-07 Buck Institute For Research On Aging N-propargylglycine: a unique inhibitor of proline dehydrogenase with brain-enhancing mitohormesis properties capable of mitigating the pathogenesis of neurodegenerative disorders
WO2025181805A1 (en) * 2024-02-27 2025-09-04 Prilenia Neurotherapeutics Ltd. Pridopidine and sigma 2 antagonist agent for treating huntington disease and symptoms thereof

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109923102A (zh) * 2016-08-24 2019-06-21 普瑞尼亚医疗发展有限公司 普利多匹定用于治疗功能下降的用途
CN110012661A (zh) * 2016-08-24 2019-07-12 普瑞尼亚医疗发展有限公司 普利多匹定用于治疗肌张力障碍的用途
CN109923102B (zh) * 2016-08-24 2022-11-15 普瑞尼亚神经治疗有限公司 普利多匹定用于治疗功能下降的用途
CN115671103A (zh) * 2016-08-24 2023-02-03 普瑞尼亚神经治疗有限公司 普利多匹定用于治疗功能下降的用途
CN111278440A (zh) * 2017-08-14 2020-06-12 普里莱尼亚神经治疗有限公司 用普利多匹定治疗肌萎缩性脊髓侧索硬化症的方法
CN111278440B (zh) * 2017-08-14 2023-04-25 普瑞尼亚神经治疗有限公司 用普利多匹定治疗肌萎缩性脊髓侧索硬化症的方法
CN111278431A (zh) * 2017-08-30 2020-06-12 普瑞尼亚神经治疗有限公司 普利多匹定的高浓度剂型
CN113950328A (zh) * 2019-06-12 2022-01-18 普瑞尼亚神经治疗有限公司 用于治疗亨廷顿病及其症状的包含普利多匹定及其类似物的组合物

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HK1221646A1 (zh) 2017-06-09
DK3010506T3 (da) 2021-07-12
US10322119B2 (en) 2019-06-18
EP3010506A4 (en) 2017-02-08
EP3010506A1 (en) 2016-04-27
KR20160055122A (ko) 2016-05-17
MX2015017307A (es) 2016-08-03
MX384234B (es) 2025-03-14
PH12015502691A1 (en) 2016-03-14
PL3010506T3 (pl) 2021-11-02
UA122999C2 (uk) 2021-02-03
JP2016523862A (ja) 2016-08-12
PE20170302A1 (es) 2017-03-31
PE20160195A1 (es) 2016-05-14
TW201529069A (zh) 2015-08-01
ES2879631T3 (es) 2021-11-22
CA2913781C (en) 2022-05-10
US20140378508A1 (en) 2014-12-25
EA201690069A1 (ru) 2016-06-30
UY35624A (es) 2015-01-30
WO2014205229A1 (en) 2014-12-24
KR102316933B1 (ko) 2021-10-26
SG11201509729YA (en) 2015-12-30
CL2015003690A1 (es) 2016-10-28
CA2913781A1 (en) 2014-12-24
IL242804B (en) 2022-02-01
WO2014205229A8 (en) 2015-04-09
AU2014281414A1 (en) 2016-01-21
BR112015029918A2 (pt) 2017-07-25
HUE054783T2 (hu) 2021-09-28
EP3010506B1 (en) 2021-05-12

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