CN105473737B - 用于检测细菌污染的方法和组合物 - Google Patents

用于检测细菌污染的方法和组合物 Download PDF

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Publication number
CN105473737B
CN105473737B CN201480041899.XA CN201480041899A CN105473737B CN 105473737 B CN105473737 B CN 105473737B CN 201480041899 A CN201480041899 A CN 201480041899A CN 105473737 B CN105473737 B CN 105473737B
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primer
sequence
seq
probe
sample
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CN105473737A (zh
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王建全
崔相民
陈晓岚
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DCH MOLECULAR DIAGNOSTICS Inc
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DCH MOLECULAR DIAGNOSTICS Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/15—Modifications characterised by incorporating a consensus or conserved sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2531/00—Reactions of nucleic acids characterised by
    • C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
    • C12Q2531/113—PCR

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN201480041899.XA 2013-07-25 2014-07-23 用于检测细菌污染的方法和组合物 Active CN105473737B (zh)

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US201361858495P 2013-07-25 2013-07-25
US61/858,495 2013-07-25
PCT/US2014/047914 WO2015013465A2 (en) 2013-07-25 2014-07-23 Methods and compositions for detecting bacterial contamination

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US (2) US10392670B2 (https=)
EP (1) EP3024947B1 (https=)
JP (3) JP2016525359A (https=)
KR (1) KR102245110B1 (https=)
CN (2) CN105473737B (https=)
AU (1) AU2014293075A1 (https=)
CA (1) CA2917430C (https=)
MX (1) MX2016000997A (https=)
SG (1) SG11201600550WA (https=)
TW (1) TWI697560B (https=)
WO (1) WO2015013465A2 (https=)

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CN105368961A (zh) * 2015-12-15 2016-03-02 天津脉络生物科技有限公司 一种沙雷菌定量检测荧光pcr试剂盒及其应用
CA3185611A1 (en) * 2016-03-25 2017-09-28 Karius, Inc. Synthetic nucleic acid spike-ins
CN105734164B (zh) * 2016-05-06 2019-05-17 苏州大学 一种检测细菌性脑膜炎病原体的多重pcr试剂盒
CN111073987B (zh) * 2016-08-30 2022-09-20 上海市生物医药技术研究院 小肠结肠炎耶尔森氏菌的快速恒温检测方法、引物组及试剂盒
US20190062809A1 (en) * 2017-08-24 2019-02-28 Clinical Micro Sensors, Inc. (dba GenMark Diagnostics, Inc.) Electrochemical detection of bacterial and/or fungal infections
CN111801429A (zh) * 2017-11-06 2020-10-20 密歇根大学董事会 用于检测微生物的组合物和方法
CN111527216A (zh) * 2017-11-13 2020-08-11 生命技术公司 用于尿路微生物检测的组合物、方法和试剂盒
EP3746565B1 (en) * 2018-01-30 2025-12-03 BioFire Defense, LLC Methods and systems for validation of a nucleic acid amplification assay
CN108148834B (zh) * 2018-03-14 2018-11-13 北京理工大学 用于检测空间环境中的真菌的引物组合、试剂盒及方法
US20210172004A1 (en) * 2018-04-13 2021-06-10 National Agricultural Genotyping Center Universal lactic acid bacteria quantification kit for fermentation monitoring
WO2020068881A1 (en) * 2018-09-24 2020-04-02 Second Genome, Inc. Compositions, systems, apparatuses, and methods for validation of microbiome sequence processing and differential abundance analyses via multiple bespoke spike-in mixtures
CN109337967A (zh) * 2018-09-27 2019-02-15 华中科技大学鄂州工业技术研究院 一种实验室的微生物污染鉴别方法
FR3097560B1 (fr) * 2019-06-24 2021-06-25 Oreal Méthode de diagnostic d’une exposition chronique à la pollution
CN111209895B (zh) * 2020-02-14 2022-03-25 李淑媛 静脉药物配制样品的细菌污染检测系统、方法及存储介质
CN112575097B (zh) * 2020-10-12 2022-05-10 南开大学 一种用于检测蜡样芽孢杆菌的液相芯片及应用
WO2022081815A1 (en) * 2020-10-14 2022-04-21 Pickens Peter Vincent Optimized detection of blood-borne microbes
JP7553323B2 (ja) 2020-10-30 2024-09-18 株式会社Kri スタフィロコッカス細菌の同定方法
CN112226528B (zh) * 2020-12-14 2021-03-16 臻和(北京)生物科技有限公司 一种用于生物组织样本检测细菌污染的质检方法
KR20240107097A (ko) * 2021-09-03 2024-07-08 마이크로노마, 인크. 암 관련 미생물 바이오마커를 식별하는 방법
CN114480596A (zh) * 2022-02-11 2022-05-13 宁波市中心血站 一种微流控血液及血制品细菌污染检测方法
US12529106B2 (en) 2023-06-09 2026-01-20 Inti Taiwan, Inc. Assays and methods to assist in vitro fertilization

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Also Published As

Publication number Publication date
EP3024947A2 (en) 2016-06-01
JP2019187431A (ja) 2019-10-31
JP2016525359A (ja) 2016-08-25
EP3024947B1 (en) 2020-10-28
US20160355871A1 (en) 2016-12-08
CA2917430C (en) 2020-10-06
US10392670B2 (en) 2019-08-27
EP3024947A4 (en) 2017-03-15
MX2016000997A (es) 2016-04-19
SG11201600550WA (en) 2016-02-26
US11274351B2 (en) 2022-03-15
KR20160034318A (ko) 2016-03-29
CA2917430A1 (en) 2015-01-29
TWI697560B (zh) 2020-07-01
AU2014293075A1 (en) 2015-12-17
JP2022023068A (ja) 2022-02-07
HK1219298A1 (en) 2017-03-31
KR102245110B1 (ko) 2021-04-27
WO2015013465A2 (en) 2015-01-29
TW201525145A (zh) 2015-07-01
CN110592244A (zh) 2019-12-20
US20200080134A1 (en) 2020-03-12
WO2015013465A3 (en) 2015-04-23
CN105473737A (zh) 2016-04-06

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